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Volumn 67, Issue 23, 2007, Pages 11455-11462

The cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine activates the extracellular signal-regulated kinase mitogen-activated protein kinase pathway

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; ESTROGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 37049033647     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-2821     Document Type: Article
Times cited : (25)

References (54)
  • 2
    • 0028128437 scopus 로고
    • Dietary carcinogens and mammary carcinogenesis. Induction of rat mammary carcinomas by administration of heterocyclic amines in cooked foods
    • Nagao M, Ushijima T, Wakabayashi K, et al. Dietary carcinogens and mammary carcinogenesis. Induction of rat mammary carcinomas by administration of heterocyclic amines in cooked foods. Cancer 1994;74:1063-9.
    • (1994) Cancer , vol.74 , pp. 1063-1069
    • Nagao, M.1    Ushijima, T.2    Wakabayashi, K.3
  • 3
    • 0030981184 scopus 로고    scopus 로고
    • Overview of carcinogenic heterocyclic amines
    • Sugimura T. Overview of carcinogenic heterocyclic amines. Mutat Res 1997;376:211-9.
    • (1997) Mutat Res , vol.376 , pp. 211-219
    • Sugimura, T.1
  • 4
    • 0025768966 scopus 로고
    • A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
    • Ito N, Hasegawa R, Sano M, et al. A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis 1991;12:1503-6.
    • (1991) Carcinogenesis , vol.12 , pp. 1503-1506
    • Ito, N.1    Hasegawa, R.2    Sano, M.3
  • 5
    • 14444288520 scopus 로고    scopus 로고
    • The prostate: A target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine (PhIP) derived from cooked foods
    • Shirai T, Sano M, Tamano S, et al. The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine (PhIP) derived from cooked foods. Cancer Res 1997;57:195-8.
    • (1997) Cancer Res , vol.57 , pp. 195-198
    • Shirai, T.1    Sano, M.2    Tamano, S.3
  • 6
    • 0141675056 scopus 로고    scopus 로고
    • Detection of 2-amino-1-methyl-6- phenylimidazo[4,5-b]-pyridine-DNA adducts in normal breast tissues and risk of breast cancer
    • Zhu J, Chang P, Bondy ML, et al. Detection of 2-amino-1-methyl-6- phenylimidazo[4,5-b]-pyridine-DNA adducts in normal breast tissues and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2003;12:830-7.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 830-837
    • Zhu, J.1    Chang, P.2    Bondy, M.L.3
  • 7
    • 34547661669 scopus 로고    scopus 로고
    • Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells
    • Ambrosone CB, Abrams SM, Gorlewska-Roberts K, Kadlubar FF. Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells. Arch Biochem Biophys 2007;464:169-75.
    • (2007) Arch Biochem Biophys , vol.464 , pp. 169-175
    • Ambrosone, C.B.1    Abrams, S.M.2    Gorlewska-Roberts, K.3    Kadlubar, F.F.4
  • 8
    • 33751357589 scopus 로고    scopus 로고
    • The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans
    • Malfatti MA, Dingley KH, Nowell-Kadlubar S, et al. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 2006;66:10541-7.
    • (2006) Cancer Res , vol.66 , pp. 10541-10547
    • Malfatti, M.A.1    Dingley, K.H.2    Nowell-Kadlubar, S.3
  • 9
    • 34247479530 scopus 로고    scopus 로고
    • Grilled meat consumption and PhIP-DNA adducts in prostate carcinogenesis
    • Tang D, Liu JJ, Rundle A, et al. Grilled meat consumption and PhIP-DNA adducts in prostate carcinogenesis. Cancer Epidemiol Biomarkers Prev 2007;16:803-8.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 803-808
    • Tang, D.1    Liu, J.J.2    Rundle, A.3
  • 10
    • 34548457350 scopus 로고    scopus 로고
    • Highly elevated PSA and dietary PhIP intake in a prospective clinic-based study among African Americans
    • Bogen KT, Keating GA, Chan JM, et al. Highly elevated PSA and dietary PhIP intake in a prospective clinic-based study among African Americans. Prostate Cancer Prostatic Dis 2007;10:261-9.
    • (2007) Prostate Cancer Prostatic Dis , vol.10 , pp. 261-269
    • Bogen, K.T.1    Keating, G.A.2    Chan, J.M.3
  • 11
    • 29244460064 scopus 로고    scopus 로고
    • A prospective study of meat and meat mutagens and prostate cancer risk
    • Cross AJ, Peters U, Kirsh VA, et al. A prospective study of meat and meat mutagens and prostate cancer risk. Cancer Res 2005;65:11779-84.
    • (2005) Cancer Res , vol.65 , pp. 11779-11784
    • Cross, A.J.1    Peters, U.2    Kirsh, V.A.3
  • 12
    • 0034674913 scopus 로고    scopus 로고
    • 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk
    • Sinha R, Gustafson DR, Kulldorff M, et al. 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk. J Natl Cancer Inst 2000;92:1352-4.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1352-1354
    • Sinha, R.1    Gustafson, D.R.2    Kulldorff, M.3
  • 13
    • 24744436428 scopus 로고    scopus 로고
    • Meat, meat cooking methods and preservation, and risk for colorectal adenoma
    • Sinha R, Peters U, Cross AJ, et al. Meat, meat cooking methods and preservation, and risk for colorectal adenoma. Cancer Res 2005;65:8034-41.
    • (2005) Cancer Res , vol.65 , pp. 8034-8041
    • Sinha, R.1    Peters, U.2    Cross, A.J.3
  • 14
    • 0028301237 scopus 로고
    • Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5- b)pyridine (PhIP) by human liver microsomes
    • Zhao K, Murray S, Davies DS, Boobis AR, Gooderham NJ. Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5- b)pyridine (PhIP) by human liver microsomes. Carcinogenesis 1994;15:1285-8.
    • (1994) Carcinogenesis , vol.15 , pp. 1285-1288
    • Zhao, K.1    Murray, S.2    Davies, D.S.3    Boobis, A.R.4    Gooderham, N.J.5
  • 15
    • 0028881705 scopus 로고
    • Determination of in vitro formed DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine using capillary liquid chromatography/electrospray ionization/tandem mass spectrometry
    • Rindgen D, Turesky RJ, Vouros P. Determination of in vitro formed DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine using capillary liquid chromatography/electrospray ionization/tandem mass spectrometry. Chem Res Toxicol 1995;8:1005-13.
    • (1995) Chem Res Toxicol , vol.8 , pp. 1005-1013
    • Rindgen, D.1    Turesky, R.J.2    Vouros, P.3
  • 16
    • 0031788510 scopus 로고    scopus 로고
    • Mammary gland carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Sprague-Dawley rats on high- and low-fat diets
    • Snyderwine EG, Thorgeirsson UP, Venugopal M, Roberts-Thomson SJ. Mammary gland carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Sprague-Dawley rats on high- and low-fat diets. Nutr Cancer 1998;31:160-7.
    • (1998) Nutr Cancer , vol.31 , pp. 160-167
    • Snyderwine, E.G.1    Thorgeirsson, U.P.2    Venugopal, M.3    Roberts-Thomson, S.J.4
  • 17
    • 0032789243 scopus 로고    scopus 로고
    • 2-Amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP) retards mammary gland involution in lactating Sprague-Dawley rats
    • Venugopal M, Callaway A, Snyderwine EG. 2-Amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP) retards mammary gland involution in lactating Sprague-Dawley rats. Carcinogenesis 1999;20:1309-14.
    • (1999) Carcinogenesis , vol.20 , pp. 1309-1314
    • Venugopal, M.1    Callaway, A.2    Snyderwine, E.G.3
  • 18
    • 0033539902 scopus 로고    scopus 로고
    • Inhibition of cell death in human mammary epithelial cells by the cooked meat-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine
    • Venugopal M, Agarwal R, Callaway A, Schut HA, Snyderwine EG. Inhibition of cell death in human mammary epithelial cells by the cooked meat-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine. Biochem Biophys Res Commun 1999;266:203-7.
    • (1999) Biochem Biophys Res Commun , vol.266 , pp. 203-207
    • Venugopal, M.1    Agarwal, R.2    Callaway, A.3    Schut, H.A.4    Snyderwine, E.G.5
  • 19
    • 10344222094 scopus 로고    scopus 로고
    • The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine is a potent oestrogen: A mechanistic basis for its tissue-specific carcinogenicity
    • Lauber SN, Ali S, Gooderham NJ. The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity. Carcinogenesis 2004;25:2509-17.
    • (2004) Carcinogenesis , vol.25 , pp. 2509-2517
    • Lauber, S.N.1    Ali, S.2    Gooderham, N.J.3
  • 20
    • 0027983664 scopus 로고
    • Environmental estrogens stir debate
    • Stone R. Environmental estrogens stir debate. Science 1994;265:308-10.
    • (1994) Science , vol.265 , pp. 308-310
    • Stone, R.1
  • 21
    • 0035931273 scopus 로고    scopus 로고
    • Estrogen metabolism and malignancy: Analysis of the expression and function of 17β-hydroxysteroid dehydrogenases in colonic cancer
    • English MA, Stewart PM, Hewison M. Estrogen metabolism and malignancy: analysis of the expression and function of 17β-hydroxysteroid dehydrogenases in colonic cancer. Mol Cell Endocrinol 2001;171:53-60.
    • (2001) Mol Cell Endocrinol , vol.171 , pp. 53-60
    • English, M.A.1    Stewart, P.M.2    Hewison, M.3
  • 22
    • 0017379672 scopus 로고
    • The development of prostatic adenocarcinoma in Nb rats following prolonged sex hormone administration
    • Noble RL. The development of prostatic adenocarcinoma in Nb rats following prolonged sex hormone administration. Cancer Res 1977;37:1929-33.
    • (1977) Cancer Res , vol.37 , pp. 1929-1933
    • Noble, R.L.1
  • 24
    • 0033555967 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase associated with prostate cancer progression
    • Gioeli D, Mandell JW, Petroni GR, Frierson HF, Jr., Weber MJ. Activation of mitogen-activated protein kinase associated with prostate cancer progression. Cancer Res 1999;59:279-84.
    • (1999) Cancer Res , vol.59 , pp. 279-284
    • Gioeli, D.1    Mandell, J.W.2    Petroni, G.R.3    Frierson Jr., H.F.4    Weber, M.J.5
  • 25
    • 33846889945 scopus 로고    scopus 로고
    • Hplc/ electrospray ionization mass spectrometric analysis of the heterocyclic aromatic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in human milk
    • Scott KA, Turesky RJ, Wainman BC, Josephy PD. Hplc/ electrospray ionization mass spectrometric analysis of the heterocyclic aromatic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in human milk. Chem Res Toxicol 2007;20:88-94.
    • (2007) Chem Res Toxicol , vol.20 , pp. 88-94
    • Scott, K.A.1    Turesky, R.J.2    Wainman, B.C.3    Josephy, P.D.4
  • 28
    • 0026447831 scopus 로고
    • Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[ 4,5-f]quinoxaline and 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef
    • Lynch AM, Knize MG, Boobis AR, Gooderham NJ, Davies DS, Murray S. Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[ 4,5-f]quinoxaline and 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef. Cancer Res 1992;52:6216-23.
    • (1992) Cancer Res , vol.52 , pp. 6216-6223
    • Lynch, A.M.1    Knize, M.G.2    Boobis, A.R.3    Gooderham, N.J.4    Davies, D.S.5    Murray, S.6
  • 29
    • 0031595405 scopus 로고    scopus 로고
    • Benzo[a] pyrene- and TCDD-induced alterations in tyrosine phosphorylation and insulin-like growth factor signaling pathways in the MCF-10A human mammary epithelial cell line
    • Tannheimer SL, Ethier SP, Caldwell KK, Burchiel SW. Benzo[a] pyrene- and TCDD-induced alterations in tyrosine phosphorylation and insulin-like growth factor signaling pathways in the MCF-10A human mammary epithelial cell line. Carcinogenesis 1998;19:1291-7.
    • (1998) Carcinogenesis , vol.19 , pp. 1291-1297
    • Tannheimer, S.L.1    Ethier, S.P.2    Caldwell, K.K.3    Burchiel, S.W.4
  • 30
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 31
    • 0030812439 scopus 로고    scopus 로고
    • Signaling mechanisms in growth factor-stimulated cell motility
    • Anand-Apte B, Zetter B. Signaling mechanisms in growth factor-stimulated cell motility. Stem Cells 1997;15:259-67.
    • (1997) Stem Cells , vol.15 , pp. 259-267
    • Anand-Apte, B.1    Zetter, B.2
  • 32
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • Soule HD, Maloney TM, Wolman SR, et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res 1990;50:6075-86.
    • (1990) Cancer Res , vol.50 , pp. 6075-6086
    • Soule, H.D.1    Maloney, T.M.2    Wolman, S.R.3
  • 33
    • 0035677301 scopus 로고    scopus 로고
    • Characterization of morphological and cytoskeletal changes in MCF10A breast epithelial cells plated on laminin-5: Comparison with breast cancer cell line MCF7
    • Kiosses WB, Hahn KM, Giannelli G, Quaranta V. Characterization of morphological and cytoskeletal changes in MCF10A breast epithelial cells plated on laminin-5: comparison with breast cancer cell line MCF7. Cell Commun Adhes 2001;8:29-44.
    • (2001) Cell Commun Adhes , vol.8 , pp. 29-44
    • Kiosses, W.B.1    Hahn, K.M.2    Giannelli, G.3    Quaranta, V.4
  • 34
    • 0032910168 scopus 로고    scopus 로고
    • Organization and regulation of mitogen-activated protein kinase signaling pathways
    • Garrington TP, Johnson GL. Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol 1999;11:211-8.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 211-218
    • Garrington, T.P.1    Johnson, G.L.2
  • 35
    • 15044351008 scopus 로고    scopus 로고
    • Regulation of tumor cell motility by ERK mitogen-activated protein kinases
    • Viala E, Pouyssegur J. Regulation of tumor cell motility by ERK mitogen-activated protein kinases. Ann N Y Acad Sci 2004;1030:208-18.
    • (2004) Ann N Y Acad Sci , vol.1030 , pp. 208-218
    • Viala, E.1    Pouyssegur, J.2
  • 36
    • 0036738640 scopus 로고    scopus 로고
    • AP-1, NF-κB, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model
    • Suzukawa K, Weber TJ, Colburn NH. AP-1, NF-κB, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model. Environ Health Perspect 2002;110:865-70.
    • (2002) Environ Health Perspect , vol.110 , pp. 865-870
    • Suzukawa, K.1    Weber, T.J.2    Colburn, N.H.3
  • 37
    • 0032530222 scopus 로고
    • Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells
    • Coutts AS, Murphy LC. Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells. Cancer Res 1988;58:4071-4.
    • (1988) Cancer Res , vol.58 , pp. 4071-4074
    • Coutts, A.S.1    Murphy, L.C.2
  • 38
    • 0032982818 scopus 로고    scopus 로고
    • Overexpression of c-erbB2 is an independent marker of resistance to endocrine therapy in advanced breast cancer
    • Houston SJ, Plunkett TA, Barnes DM, et al. Overexpression of c-erbB2 is an independent marker of resistance to endocrine therapy in advanced breast cancer. Br J Cancer 1999;79:1220-6.
    • (1999) Br J Cancer , vol.79 , pp. 1220-1226
    • Houston, S.J.1    Plunkett, T.A.2    Barnes, D.M.3
  • 39
    • 18844427567 scopus 로고    scopus 로고
    • Up-regulation of PKC-δ contributes to antiestrogen resistance in mammary tumor cells
    • Nabha SM, Glaros S, Hong M, et al. Up-regulation of PKC-δ contributes to antiestrogen resistance in mammary tumor cells. Oncogene 2005;24:3166-76.
    • (2005) Oncogene , vol.24 , pp. 3166-3176
    • Nabha, S.M.1    Glaros, S.2    Hong, M.3
  • 40
    • 0027309375 scopus 로고
    • Relationship between EGF-R, c-erbB-2 protein expression and Ki67 immunostaining in breast cancer and hormone sensitivity
    • Nicholson RI, McClelland RA, Finlay P, et al. Relationship between EGF-R, c-erbB-2 protein expression and Ki67 immunostaining in breast cancer and hormone sensitivity. Eur J Cancer 1993;29A:1018-23.
    • (1993) Eur J Cancer , vol.29 A , pp. 1018-1023
    • Nicholson, R.I.1    McClelland, R.A.2    Finlay, P.3
  • 41
    • 0031051830 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: Correlation with clinical parameters and disease-free survival
    • Rocha RL, Hilsenbeck SG, Jackson JG, et al. Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival. Clin Cancer Res 1997;3:103-9.
    • (1997) Clin Cancer Res , vol.3 , pp. 103-109
    • Rocha, R.L.1    Hilsenbeck, S.G.2    Jackson, J.G.3
  • 42
    • 0032819983 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase in human prostate cancer
    • Price DT, Della RG, Guo C, et al. Activation of extracellular signal-regulated kinase in human prostate cancer. J Urol 1999;162:1537-42.
    • (1999) J Urol , vol.162 , pp. 1537-1542
    • Price, D.T.1    Della, R.G.2    Guo, C.3
  • 43
    • 0043163868 scopus 로고    scopus 로고
    • EGFR family signaling and its association with breast cancer development and resistance to chemotherapy
    • Navolanic PM, Steelman LS, McCubrey JA. EGFR family signaling and its association with breast cancer development and resistance to chemotherapy. Int J Oncol 2003;22:237-52.
    • (2003) Int J Oncol , vol.22 , pp. 237-252
    • Navolanic, P.M.1    Steelman, L.S.2    McCubrey, J.A.3
  • 44
    • 0033913213 scopus 로고    scopus 로고
    • Signaling pathways in insulin action: Molecular targets of insulin resistance
    • Pessin JE, Saltiel AR. Signaling pathways in insulin action: molecular targets of insulin resistance. J Clin Invest 2000;106:165-9.
    • (2000) J Clin Invest , vol.106 , pp. 165-169
    • Pessin, J.E.1    Saltiel, A.R.2
  • 45
    • 15044339847 scopus 로고    scopus 로고
    • Role of p44/ 42 mitogen activated protein kinase signal transduction in PC-3 cells, a line of hormone independent prostate cancer cells
    • Koul HK, Chaturvedi L, Haung MY, et al. Role of p44/ 42 mitogen activated protein kinase signal transduction in PC-3 cells, a line of hormone independent prostate cancer cells. Proc Am Assoc Cancer Res 2003;44:852.
    • (2003) Proc Am Assoc Cancer Res , vol.44 , pp. 852
    • Koul, H.K.1    Chaturvedi, L.2    Haung, M.Y.3
  • 46
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E, Mahadevan LC. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 1995;20:117-22.
    • (1995) Trends Biochem Sci , vol.20 , pp. 117-122
    • Cano, E.1    Mahadevan, L.C.2
  • 47
    • 11144220883 scopus 로고    scopus 로고
    • Stimulation of catecholamine synthesis by environmental estrogenic pollutants
    • Yanagihara N, Toyohira Y, Ueno S, et al. Stimulation of catecholamine synthesis by environmental estrogenic pollutants. Endocrinology 2005;146:265-72.
    • (2005) Endocrinology , vol.146 , pp. 265-272
    • Yanagihara, N.1    Toyohira, Y.2    Ueno, S.3
  • 48
    • 3042547161 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates c-fos upregulation by 17β-estradiol and phytoestrogens in breast cancer cells
    • Maggiolini M, Vivacqua A, Fasanella G, et al. The G protein-coupled receptor GPR30 mediates c-fos upregulation by 17β-estradiol and phytoestrogens in breast cancer cells. J Biol Chem 2004;279:27008-16.
    • (2004) J Biol Chem , vol.279 , pp. 27008-27016
    • Maggiolini, M.1    Vivacqua, A.2    Fasanella, G.3
  • 49
    • 0031878769 scopus 로고    scopus 로고
    • Proliferation, development and DNA adduct levels in the mammary gland of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a high fat diet
    • Snyderwine EG, Davis CD, Schut HA, Roberts-Thomson SJ. Proliferation, development and DNA adduct levels in the mammary gland of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a high fat diet. Carcinogenesis 1998;19:1209-15.
    • (1998) Carcinogenesis , vol.19 , pp. 1209-1215
    • Snyderwine, E.G.1    Davis, C.D.2    Schut, H.A.3    Roberts-Thomson, S.J.4
  • 51
    • 33846220744 scopus 로고    scopus 로고
    • Mechanisms of action of the carcinogenic heterocyclic amine PhIP
    • Gooderham NJ, Creton S, Lauber SN, Zhu H. Mechanisms of action of the carcinogenic heterocyclic amine PhIP. Toxicol Lett 2007;168:269-77.
    • (2007) Toxicol Lett , vol.168 , pp. 269-277
    • Gooderham, N.J.1    Creton, S.2    Lauber, S.N.3    Zhu, H.4
  • 52
    • 27144488095 scopus 로고    scopus 로고
    • PhIP carcinogenicity in breast cancer: Computational and experimental evidence for competitive interactions with human estrogen receptor
    • Bennion BJ, Cosman M, Lightstone FC, et al. PhIP carcinogenicity in breast cancer: computational and experimental evidence for competitive interactions with human estrogen receptor. Chem Res Toxicol 2005;18:1528-36.
    • (2005) Chem Res Toxicol , vol.18 , pp. 1528-1536
    • Bennion, B.J.1    Cosman, M.2    Lightstone, F.C.3
  • 53
    • 33847065970 scopus 로고    scopus 로고
    • The dietary charred meat carcinogen 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine acts as both a tumor initiator and promoter in the rat ventral prostate
    • Nakai Y, Nelson WG, De Marzo AM. The dietary charred meat carcinogen 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine acts as both a tumor initiator and promoter in the rat ventral prostate. Cancer Res 2007;67:1378-84.
    • (2007) Cancer Res , vol.67 , pp. 1378-1384
    • Nakai, Y.1    Nelson, W.G.2    De Marzo, A.M.3
  • 54
    • 0031721084 scopus 로고    scopus 로고
    • Metabolism of 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1
    • Crofts FG, Sutter TR, Strickland PT. Metabolism of 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1. Carcinogenesis 1998;19:1969-73.
    • (1998) Carcinogenesis , vol.19 , pp. 1969-1973
    • Crofts, F.G.1    Sutter, T.R.2    Strickland, P.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.