Mammary gland carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine in Sprague-Dawley rats on high- and low-fat diets

Nutrition and Cancer

Volumn 31, Issue 3, 1998, Pages 160-167

  Snyderwine, Elizabeth G ^a,c   Thorgeirsson, Unnur P ^a   Venugopal, Meenakshi ^a   Roberts Thomson, Sarah J ^a,b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; CORN OIL; CYCLINE; DNA NUCLEOTIDYLEXOTRANSFERASE; HETEROCYCLIC AMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST ADENOMA; BREAST CARCINOGENESIS; BREAST CARCINOMA; BREAST FIBROADENOMA; CANCER INCIDENCE; CARCINOGENICITY; CONTROLLED STUDY; FAT INTAKE; FEMALE; LIPID DIET; LOW FAT DIET; NONHUMAN; RAT;

ANIMALIA; ZEA MAYS;

EID: 0031788510     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635589809514698     Document Type: Article

References (53)

1. Kelsey, JL, and Horn-Ross, PL: Breast cancer: magnitude of the problem and descriptive epidemiology. Epidemiol Rev 15, 7-17, 1993.
2. Greenwald, P, Sherwood, K, and McDonald, SS: Fat, caloric intake, and obesity: lifestyle risk factors for breast cancer. J Am Diet Assoc 97 Suppl, S24-S30, 1997.
3. Wynder, EL, Cohen, LA, Muscat, JE, Winters, B, Dwyer, JT, et al.: Breast cancer: weighing the evidence for a promoting role of dietary fat. JNCI 89, 766-775, 1997.
4. Adlercreutz, H, Mousavi, Y, and Hockerstedt, K: Diet and breast cancer. Acta Oncol 31, 175-181, 1992.
5. Greenwald, P, Clifford, C, Pilch, S, Heimendinger, J, and Kelloff, G: New directions in dietary studies in cancer: The National Cancer Institute. In Nutrition and Biotechnology in Heart Disease and Cancer, JB Longenecker, D. Kritchevsky, and M. K. Drezner. New York: Plenum, 1995, pp 229-239.
6. Hunter, KJ, and Willett, WC: Diet, body build, and breast cancer. Annu Rev Nutr 14, 393-418, 1994.
7. Carroll, KK, Braden, LM, Bell, JA, and Kalamegham, R: Fat and cancer. Cancer 58, 1818-1825, 1986.
8. Knekt, P, Steineck, G, Järvinen, R, Hakulinen, T, and Aromaa, A: Intake of fried meat and risk of cancer: a follow-up study in Finland. Int J Cancer 59, 756-760, 1994.
9. Ronco, A, De Stefani, E, Mendilaharsu, M, and Deneo-Pellegrini, H: Meat, fat and risk of breast cancer: a case-control study from Uruguay. Int J Cancer 65, 328-331, 1996.
10. De Stefani, E, Ronco, A, Mendilaharsu, M, Guidobono, M, and Deneo-Pellegrini, H: Meat intake, heterocyclic amines, and risk of breast cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 6, 573-581, 1997.
11. Weisburger, JH, Rivenson, A, Kingston, DGI, Wilkins, TD, Van-Tassell, RL, et al.: Dietary modulation of the carcinogenicity of the heterocyclic amines. In Heterocyclic Amines in Cooked Foods: Possible Human Carcinogens, RH Adamson, J-Å Gustafsson, N Ito, M Nagao, T Sugimura et al. (eds). Princeton, NJ: Princeton Scientific, 1995, pp 240-250.
12. Snyderwine, EG: Some perspectives of the nutritional aspects of breast cancer research. Cancer 74, 1070-1077, 1994.
13. Hunter, DJ, and Willett, WC: Nutrition and breast cancer. Cancer Causes Control 7, 56-68, 1996.
14. Sugimura, T: Mutagens, carcinogens, and tumor promoters in our daily food. Cancer 49, 1970-1984, 1982.
15. Sugimura, T: Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process. Mutat Res 150, 33-41, 1985.
16. Felton, JS, Knize, MG, Shen, NH, Andresen, BD, Bjeldanes, LF, et al.: Identification of the mutagens in cooked beef. Environ Health Perspect 67, 17-24, 1986.
17. Wakabayashi, K, Ushiyama, H, Makoto, T, Nukaya, H, Kim, S-B, et al.: Exposure to heterocyclic amines. Environ Health Perspect 99, 129-133, 1993.
18. Felton, JS, and Knize, MG: Heterocyclic-amine mutagens/carcinogens in foods. In Handbook of Experimental Pharmacology, CS Cooper and PL Grover (eds). Berlin: Springer-Verlag, 1990, vol 94/I, pp 471-502.
19. Layton, DW, Bogen, KT, Knize, MG, Hatch, FT, Johnson, VM, et al.: Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research. Carcinogenesis 16, 39-52, 1995.
20. Sinha, R, Rothman, N, Brown, ED, Salmon, CP, Knize, MG, et al.: High concentrations of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) occur in chicken but are dependent on the cooking method. Cancer Res 55, 4516-4519, 1995.
21. Ho, N, Hasegawa, R, Sano, M, Tamano, S, Esumi, H, et al.: A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis 12, 1503-1506, 1991.
22. Hasegawa, R, Sano, M, Tamano, S, Imaida, K, Shirai, T, et al.: Dose dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenicity in rats. Carcinogenesis 14, 2553-2557, 1993.
23. Imaida, K, Hagiwara, A, Yada, H, Masui, T, Hasegawa, R, et al.: Dose-dependent induction of mammary carcinomas in female Sprague-Dawley rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. JPNJ Cancer Res 87, 116-1120, 1996.
24. Ghoshal, A, Preisegger, K-H, Takayama, S, Thorgeirsson, SS, and Snyderwine, EG: Induction of mammary tumors in female Sprague-Dawley rats by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and effect of dietary fat. Carcinogenesis 15, 2429-2433, 1994.
25. El-Bayoumy, K, Chae, Y-H, Upadhyaya, P, Rivenson, A, Kurtzke, C, et al.: Comparative tumorigenicity of benzo[a]pyrene, 1-nitropyrene, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine administered by gavage to female CD rats. Carcinogenesis 16, 431-434, 1995.
26. Gammal, EB, Carroll, KK, and Plunkett, ER: Effects of dietary fat on mammary Carcinogenesis by 7,12-dimethylbenz[a]anthracene in rats. Cancer Res 27, 1737-1742, 1967.
27. Carroll, KK, and Khor, HT: Effects of dietary fat and dose level of 7,12-dimethylbenz[a]anthracene on mammary tumor incidence in rats. Cancer Res 30, 2260-2264, 1970.
28. Carroll, KK, and Khor, HT: Effects of level and type of dietary fat on incidence of mammary tumors induced in female Sprague-Dawley rats by 7,12-dimethylbenz[a]anthracene. Lipids 6, 415-420, 1971.
29. Hopkins, GJ, Kennedy, TG, and Carroll, KK: Polyunsaturated fatty acids as promoters of mammary carcinogenesis induced in Sprague-Dawley rats by 7,12-dimethylbenz[a]anthracene. JNCI 66, 517-522, 1981.
30. Rogers, AE, Conner, B, Boulanger, C, and Lee, S: Mammary tumorigenesis in rats fed diets high in lard. Lipids 21, 275-280, 1986.
31. Chan, P-C, Ferguson, KA, and Dao, TL: Effects of different dietary fats on mammary carcinogenesis. Cancer Res 43, 1079-1083, 1983.
32. Rogers, AE, and Lee, SY: Chemically induced mammary gland tumors in rats: modulation by dietary fat. In Progress in Clinical and Biological Research. Dietary Fat and Cancer, C Ip, DF Birt, AE Rogers, and C Mettlin (eds). New York: Liss, 1986, vol 222, pp 255-282.
33. Ip, C, Carter, CA, and Ip, MM: Requirement of essential fatty acid for mammary tumorigenesis in the rat. Cancer Res 45, 1997-2001, 1985.
34. Rose, DP, Connolly, JM, and Liu, X-H: Effects of linoleic acid on the growth and metastasis of two human breast cancer cell lines in nude mice and the invasive capacity of these cell lines in vitro. Cancer Res 54, 6557-6562, 1994.
35. Liu, X-H, Connolly, JM, and Rose, DP: Eicosanoids and mediators of linoleic acid-stimulated invasion and type IV collagenase production by a metastatic human breast cancer cell line. Clin Exp Metastasis 14, 145-152, 1996.
36. Rose, DP, Connolly, JM, and Liu, X-H: Effects of linoleic acid and γ-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. Nutr Cancer 24, 33-45, 1995.
37. Huggins, C, Grand, LC, and Brillantes, FP: Mammary cancer induced by a single feeding of polynuclear hydrocarbon and its suppression. Nature 189, 204-207, 1961.
38. Russo, J, Russo, IH, van Zwieten, MJ, Rogers, AE, and Gusterson, B: Classification of neoplastic and nonneoplastic lesions of the rats mammary gland. In Integument and Mammary Glands, TC Jones and U Mohr (eds). New York: Springer-Verlag, 1989, pp 275-304.
39. Russo, J, Gusterson, BA, Robers, AE, Russo, IH, Wellings, SR, et al.: Biology of disease. Comparative study of human and rat mammary tumorigenesis. Lab Invest 62, 244-278, 1990.
40. Sasa, M, Komaki, K, Tsuzuki, H, Kamamura, Y, Mon, T, et al.: Tumor progression accompanied by increase in proliferation rate in breast cancer: a preliminary report. J Surg Oncol 54, 255-259, 1993.
41. Wyllie, AH: Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview. Cancer Metastasis Rev 11, 95-103, 1992.
42. Grasl-Kraupp, B, Bursch, W, Ruttkay-Nedecky, B, Wagner, A, Lauer, B, et al.: Food restriction eliminates preneoplastic cells through apoptosis and antagonizes carcinogenesis in rat liver. Proc Natl Acad Sci USA 91, 9995-9999, 1994.
43. Aylsworth, CF, Cullum, ME, Zile, MH, and Welsh, CW: Influence of dietary retinyl acetate on normal rat mammary gland development and on the enhancement of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumorigenesis by high levels of dietary fat. JNCI 76, 339-345, 1986.
44. Kumaki, T, and Noguchi, M: Effects of high dietary fat on the total DNA and receptor content in rats with 7,12-dimethylbenz[a]anthra-cene-induced mammary carcinoma. Oncology 47, 352-358, 1990.
45. Snyderwine, EG, Davis, CD, Schut, HAJ, and Roberts-Thomson, SJ: Proliferation, development and DNA adduct levels in the mammary gland of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high fat diet. Carcinogenesis 19, 1209-1215, 1998.
46. Nagao, M, Ushijima, T, Wakabayashi, K, Ochiai, M, Kushida, H, et al.: Dietary carcinogens and mammary carcinogenesis. Induction of rat mammary carcinomas by administration of heterocyclic amines in cooked foods. Cancer 74, 1063-1069, 1994.
47. Toyota, M, Ushijima, T, Weisburger, JH, Hosoya, Y, Canzian, F, et al.: Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Mol Carcinog 15, 176-182, 1996.
48. Roberts-Thomson, SJ, and Snyderwine, EG: Effect of dietary fat on codon 12 and 13 Ha-ras gene mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced rat mammary gland tumors. Mol Carcinog 20, 348-354, 1997.
49. Davis CD, and Snyderwine, EG: Analysis of EGFR, TGF-α, Neu and c-Myc in 2-amino-1-methyl-6-phenyumidazo[4,5-fc]pyridine-induced mammary tumors using RT-PCR. Carcinogenesis 16, 3087-3092, 1995
50. Welsch, CW, House, JL, Herr, BL, Eliasberg, SJ, and Welsch, MA: Enhancement of mammary carcinogenesis by high levels of dietary fat: a phenomenon dependent on ad libitum feeding. JNCI 82, 1615-1620, 1990.
51. Hunter, DJ, and Willett, WC: Nutrition and breast cancer. Cancer Causes Control 7, 56-68, 1996.
52. Brinton, LA, and Swanson, CA: Height and weight at various ages and risk of breast cancer. Ann Epidemiol 2, 597-609, 1992.
53. Huang, Z, Hankinson, SE, Colditz, GA, Stampfer, MJ, Hunter, DJ, et al.: Dual effects of weight and weight gain on breast cancer risk. J Am Med Assoc 278, 1407-1411, 1997.