-
1
-
-
33749011163
-
The NCI60 human tumour cell line anticancer drug screen
-
Shoemaker RH. The NCI60 human tumour cell line anticancer drug screen. Nat Rev Cancer 2006;6:813-23.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 813-823
-
-
Shoemaker, R.H.1
-
2
-
-
8444248220
-
Integromic analysis of the NCI-60 cancer cell lines
-
Weinstein JN. Integromic analysis of the NCI-60 cancer cell lines. Breast Dis 2004;19:11-22.
-
(2004)
Breast Dis
, vol.19
, pp. 11-22
-
-
Weinstein, J.N.1
-
4
-
-
0030846212
-
Alterations in DNA methylation: A fundamental aspect of neoplasia
-
Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP. Alterations in DNA methylation: a fundamental aspect of neoplasia. Advances in Cancer Research 1998;72:141-96.
-
(1998)
Advances in Cancer Research
, vol.72
, pp. 141-196
-
-
Baylin, S.B.1
Herman, J.G.2
Graff, J.R.3
Vertino, P.M.4
Issa, J.P.5
-
5
-
-
0018370141
-
Direct detection of methylated cytosine in DNA by use of the restriction enzyme Mspi
-
Cedar H, Solage A, Glaser G, Razin A. Direct detection of methylated cytosine in DNA by use of the restriction enzyme Mspi. Nucleic Acids Research 1979;6:2125-32.
-
(1979)
Nucleic Acids Research
, vol.6
, pp. 2125-2132
-
-
Cedar, H.1
Solage, A.2
Glaser, G.3
Razin, A.4
-
6
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones PA, Laird PW. Cancer epigenetics comes of age. Nature Genetics 1999;21:163-7.
-
(1999)
Nature Genetics
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
7
-
-
29244438955
-
DNA methylation in the treatment of hematologic malignancies
-
Issa JP. DNA methylation in the treatment of hematologic malignancies. Clin Adv Hematol Oncol 2005;3:684-6.
-
(2005)
Clin Adv Hematol Oncol
, vol.3
, pp. 684-686
-
-
Issa, J.P.1
-
8
-
-
0029784608
-
Methylation of the estrogen receptor CpG island in lung tumors is related to the specific type of carcinogen exposure
-
Issa JPJ, Baylin SB, Belinsky SA. Methylation of the estrogen receptor CpG island in lung tumors is related to the specific type of carcinogen exposure. Cancer Research 1996;56:3655-8.
-
(1996)
Cancer Research
, vol.56
, pp. 3655-3658
-
-
Issa, J.P.J.1
Baylin, S.B.2
Belinsky, S.A.3
-
9
-
-
0032949084
-
Estrogen receptor methylation is associated with improved survival in adult acute myeloid leukemia
-
Li Q, Kopecky KJ, Mohan A, et al. Estrogen receptor methylation is associated with improved survival in adult acute myeloid leukemia. Clinical Cancer Research 1999;5:1077-84.
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 1077-1084
-
-
Li, Q.1
Kopecky, K.J.2
Mohan, A.3
-
10
-
-
33745056414
-
Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer
-
Agrelo R, Cheng WH, Setien F, et al. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. Proc Natl Acad Sci U S A 2006;103:8822-7.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 8822-8827
-
-
Agrelo, R.1
Cheng, W.H.2
Setien, F.3
-
11
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000;343:1350-4.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
12
-
-
9144239265
-
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer
-
Satoh A, Toyota M, Itoh F, et al . Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer. Cancer Res 2003;63:8606-13.
-
(2003)
Cancer Res
, vol.63
, pp. 8606-8613
-
-
Satoh, A.1
Toyota, M.2
Itoh, F.3
-
14
-
-
0030825309
-
COBRA: A sensitive and quantitative DNA methylation assay
-
Xiong ZG, Laird PW. COBRA: A sensitive and quantitative DNA methylation assay. Nucleic Acids Research 1997;25:2532-4.
-
(1997)
Nucleic Acids Research
, vol.25
, pp. 2532-2534
-
-
Xiong, Z.G.1
Laird, P.W.2
-
15
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996;93:9821-6.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
16
-
-
0032401808
-
Aging and DNA methylation in colorectal mucosa and cancer
-
Ahuja N, Li Q, Mohan AL, Baylin SB, Issa JPJ. Aging and DNA methylation in colorectal mucosa and cancer. Cancer Research 1998;58:5489-94.
-
(1998)
Cancer Research
, vol.58
, pp. 5489-5494
-
-
Ahuja, N.1
Li, Q.2
Mohan, A.L.3
Baylin, S.B.4
Issa, J.P.J.5
-
17
-
-
33947218451
-
RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis
-
Boumber YA, Kondo Y, Chen X, et al. RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. Cancer Res 2007;67:1997-2005.
-
(2007)
Cancer Res
, vol.67
, pp. 1997-2005
-
-
Boumber, Y.A.1
Kondo, Y.2
Chen, X.3
-
18
-
-
0035795676
-
Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression
-
Burbee DG, Forgacs E, Zochbauer-Muller S, et al. Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J Natl Cancer Inst 2001;93:691-9.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 691-699
-
-
Burbee, D.G.1
Forgacs, E.2
Zochbauer-Muller, S.3
-
19
-
-
0038678777
-
Sensitive and quantitative universal Pyrosequencing (TM) methylation analysis of CpG sites
-
Colella S, Shen L, Baggerly KA, Issa JPJ, Krahe R. Sensitive and quantitative universal Pyrosequencing (TM) methylation analysis of CpG sites. Biotechniques 2003;35:146-50.
-
(2003)
Biotechniques
, vol.35
, pp. 146-150
-
-
Colella, S.1
Shen, L.2
Baggerly, K.A.3
Issa, J.P.J.4
Krahe, R.5
-
20
-
-
0033565514
-
Transcriptionalsil encing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5′ CpG island methylation
-
Corn PG, Kuerbitz SJ, van Noesel MM, et al. Transcriptionalsil encing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5′ CpG island methylation. Cancer Research 1999;59:3352-6.
-
(1999)
Cancer Research
, vol.59
, pp. 3352-3356
-
-
Corn, P.G.1
Kuerbitz, S.J.2
van Noesel, M.M.3
-
21
-
-
0033740401
-
E-cadherin expression is silenced by 5′ CpG island methylation in acute leukemia
-
Corn PG, Smith BD, Ruckdeschel ES, Douglas D, Baylin SB, Herman JG. E-cadherin expression is silenced by 5′ CpG island methylation in acute leukemia. Clinical Cancer Research 2000;6:4243-8.
-
(2000)
Clinical Cancer Research
, vol.6
, pp. 4243-4248
-
-
Corn, P.G.1
Smith, B.D.2
Ruckdeschel, E.S.3
Douglas, D.4
Baylin, S.B.5
Herman, J.G.6
-
22
-
-
0035890771
-
Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily
-
Du Y, Carling T, Fang W, Piao Z, Sheu JC, Huang S. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res 2001;61:8094-9.
-
(2001)
Cancer Res
, vol.61
, pp. 8094-8099
-
-
Du, Y.1
Carling, T.2
Fang, W.3
Piao, Z.4
Sheu, J.C.5
Huang, S.6
-
23
-
-
0032532092
-
Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia
-
Esteller M, Corn PG, Urena JM, Gabrielson E, Baylin SB, Herman JG. Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia. Cancer Research 1998;58:4515-8.
-
(1998)
Cancer Research
, vol.58
, pp. 4515-4518
-
-
Esteller, M.1
Corn, P.G.2
Urena, J.M.3
Gabrielson, E.4
Baylin, S.B.5
Herman, J.G.6
-
24
-
-
2442577021
-
Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation
-
Kondo Y, Shen L, Yan PS, Huang THM, Issa JPJ. Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Proc Natl Acad Sci U S A 2004;101:7398-403.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7398-7403
-
-
Kondo, Y.1
Shen, L.2
Yan, P.S.3
Huang, T.H.M.4
Issa, J.P.J.5
-
25
-
-
20244368980
-
Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours
-
Murai M, Toyota M, Satoh A, et al. Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours. Br J Cancer 2005;92:1165-72.
-
(2005)
Br J Cancer
, vol.92
, pp. 1165-1172
-
-
Murai, M.1
Toyota, M.2
Satoh, A.3
-
26
-
-
0037372967
-
p14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53
-
Shen L, Kondo Y, Hamilton SR, Rashid A, Issa JPJ. p14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53. Gastroenterology 2003;124:626-33.
-
(2003)
Gastroenterology
, vol.124
, pp. 626-633
-
-
Shen, L.1
Kondo, Y.2
Hamilton, S.R.3
Rashid, A.4
Issa, J.P.J.5
-
27
-
-
25144518262
-
MGMT promoter methylation and field defect in sporadic colorectal cancer
-
Shen L, Kondo Y, Rosner GL, et al. MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst 2005;97:1330-8.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1330-1338
-
-
Shen, L.1
Kondo, Y.2
Rosner, G.L.3
-
28
-
-
0037625237
-
Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia
-
Shen LL, Toyota M, Kondo Y, et al. Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. Blood 2003;101:4131-6.
-
(2003)
Blood
, vol.101
, pp. 4131-4136
-
-
Shen, L.L.1
Toyota, M.2
Kondo, Y.3
-
29
-
-
0032739329
-
CpG island methylator phenotypes in aging and cancer
-
Toyota M, Issa JPJ. CpG island methylator phenotypes in aging and cancer. Semin Cancer Biol199 9;9:349-57.
-
Semin Cancer Biol199 9
, vol.9
, pp. 349-357
-
-
Toyota, M.1
Issa, J.P.J.2
-
30
-
-
0033894117
-
Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors
-
Toyota M, Shen L, Ohe-Toyota M, Hamilton SR, Sinicrope FA, Issa JPJ. Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors. Cancer Research 2000;60:4044-8.
-
(2000)
Cancer Research
, vol.60
, pp. 4044-4048
-
-
Toyota, M.1
Shen, L.2
Ohe-Toyota, M.3
Hamilton, S.R.4
Sinicrope, F.A.5
Issa, J.P.J.6
-
31
-
-
0034674916
-
Promoter methylation and silencing of the retinoic acid receptor-β gene in lung carcinomas
-
Virmani AK, Rathi A, Zochbauer-Muller S, et al. Promoter methylation and silencing of the retinoic acid receptor-β gene in lung carcinomas. J Natl Cancer Inst 2000;92:1303-7.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1303-1307
-
-
Virmani, A.K.1
Rathi, A.2
Zochbauer-Muller, S.3
-
32
-
-
0034088857
-
A gene expression database for the molecular pharmacology of cancer
-
Scherf U, Ross DT, Waltham M, et al. A gene expression database for the molecular pharmacology of cancer. Nat Genet 2000;24:236-44.
-
(2000)
Nat Genet
, vol.24
, pp. 236-244
-
-
Scherf, U.1
Ross, D.T.2
Waltham, M.3
-
33
-
-
0024312538
-
Display and analysis of patterns of differential activity of drugs against human tumor cell lines: Development of mean graph and COMPARE algorithm
-
Paull KD, Shoemaker RH, Hodes L, et al. Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm. J Natl Cancer Inst 1989;81:1088-92.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 1088-1092
-
-
Paull, K.D.1
Shoemaker, R.H.2
Hodes, L.3
-
34
-
-
0026498426
-
Neural computing in cancer drug development: Predicting mechanism of action
-
Weinstein JN, Kohn KW, Grever MR, et al. Neural computing in cancer drug development: predicting mechanism of action. Science 1992;258:447-51.
-
(1992)
Science
, vol.258
, pp. 447-451
-
-
Weinstein, J.N.1
Kohn, K.W.2
Grever, M.R.3
-
35
-
-
0031741138
-
Viral oncoproteins discriminate between p53 and the p53 homolog p73
-
Marin MC, Jost CA, Irwin MS, DeCaprio JA, Caput D, Kaelin WG, Jr. Viral oncoproteins discriminate between p53 and the p53 homolog p73. Mol Cell Biol 1998;18:6316-24.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6316-6324
-
-
Marin, M.C.1
Jost, C.A.2
Irwin, M.S.3
DeCaprio, J.A.4
Caput, D.5
Kaelin Jr, W.G.6
-
36
-
-
0041997348
-
Chemosensitivity linked to p73 function
-
Irwin MS, Kondo K, Marin MC, Cheng LS, Hahn WC, Kaelin WG, Jr. Chemosensitivity linked to p73 function. Cancer Cell 2003;3:403-10.
-
(2003)
Cancer Cell
, vol.3
, pp. 403-410
-
-
Irwin, M.S.1
Kondo, K.2
Marin, M.C.3
Cheng, L.S.4
Hahn, W.C.5
Kaelin Jr., W.G.6
-
37
-
-
0025894092
-
Cadherin cell adhesion receptors as a morphogenetic regulator
-
Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 1991;251:1451-5.
-
(1991)
Science
, vol.251
, pp. 1451-1455
-
-
Takeichi, M.1
-
38
-
-
0028152397
-
Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis
-
Lee WH, Morton RA, Epstein JI, et al. Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. Proc Natl Acad Sci U S A 1994;91:11733-7.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11733-11737
-
-
Lee, W.H.1
Morton, R.A.2
Epstein, J.I.3
-
39
-
-
33744789155
-
CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus
-
Chang MS, Uozaki H, Chong JM, et al. CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus. Clin Cancer Res 2006;12:2995-3002.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2995-3002
-
-
Chang, M.S.1
Uozaki, H.2
Chong, J.M.3
-
40
-
-
0034662645
-
Aberrant methylation of the estrogen receptor and E-cadherin 5′ CpG islands increases with malignant progression in human breast cancer
-
Nass SJ, Herman JG, Gabrielson E, et al. Aberrant methylation of the estrogen receptor and E-cadherin 5′ CpG islands increases with malignant progression in human breast cancer. Cancer Res 2000;60:4346-8.
-
(2000)
Cancer Res
, vol.60
, pp. 4346-4348
-
-
Nass, S.J.1
Herman, J.G.2
Gabrielson, E.3
-
41
-
-
0037531563
-
Distinct methylation profiles of glioma subtypes
-
Uhlmann K, Rohde K, Zeller C, et al. Distinct methylation profiles of glioma subtypes. Int J Cancer 2003;106:52-9.
-
(2003)
Int J Cancer
, vol.106
, pp. 52-59
-
-
Uhlmann, K.1
Rohde, K.2
Zeller, C.3
-
42
-
-
5144220196
-
Molecular detection of prostate cancer: A role for GSTP1 hypermethylation
-
Henrique R, Jeronimo C. Molecular detection of prostate cancer: a role for GSTP1 hypermethylation. Eur Urol200 4;46:660-9.
-
Eur Urol200 4
, vol.46
, pp. 660-669
-
-
Henrique, R.1
Jeronimo, C.2
-
43
-
-
0034307067
-
Allelic loss of chromosome 1p and radiotherapy plus chemotherapy in patients with oligodendrogliomas
-
Bauman GS, Ino Y, Ueki K, et al. Allelic loss of chromosome 1p and radiotherapy plus chemotherapy in patients with oligodendrogliomas. Int J Radiat Oncol Biol Phys 2000;48:825-30.
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.48
, pp. 825-830
-
-
Bauman, G.S.1
Ino, Y.2
Ueki, K.3
-
44
-
-
0033600235
-
p73 is regulated by tyrosine kinase c-Ablin the apoptotic response to DNA damage
-
Yuan ZM, Shioya H, Ishiko T, et al. p73 is regulated by tyrosine kinase c-Ablin the apoptotic response to DNA damage. Nature 1999;399:814-7.
-
(1999)
Nature
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
-
45
-
-
0035161816
-
Functional interactions and signaling properties of mammalian DNA mismatch repair proteins
-
Bellacosa A. Functional interactions and signaling properties of mammalian DNA mismatch repair proteins. Cell Death Differ 2001;8:1076-92.
-
(2001)
Cell Death Differ
, vol.8
, pp. 1076-1092
-
-
Bellacosa, A.1
-
46
-
-
0032476743
-
Two new p73 splice variants, γ and δ, with different transcriptional activity
-
De LV, Costanzo A, Barcaroli D, et al. Two new p73 splice variants, γ and δ, with different transcriptional activity. J Exp Med 1998;188:1763-8.
-
(1998)
J Exp Med
, vol.188
, pp. 1763-1768
-
-
LV, D.1
Costanzo, A.2
Barcaroli, D.3
-
47
-
-
0032533514
-
The potential tumor suppressor p73 differentially regulates cellular p53 target genes
-
Zhu J, Jiang J, Zhou W, Chen X. The potential tumor suppressor p73 differentially regulates cellular p53 target genes. Cancer Res 1998;58:5061-5.
-
(1998)
Cancer Res
, vol.58
, pp. 5061-5065
-
-
Zhu, J.1
Jiang, J.2
Zhou, W.3
Chen, X.4
-
48
-
-
0036125352
-
Role of p73 in malignancy: Tumor suppressor or oncogene?
-
Stiewe T, Putzer BM. Role of p73 in malignancy: tumor suppressor or oncogene? Cell Death Differ 2002;9:237-45.
-
(2002)
Cell Death Differ
, vol.9
, pp. 237-245
-
-
Stiewe, T.1
Putzer, B.M.2
-
49
-
-
0034745717
-
P73a overexpression is associated with resistance to treatment with DNA-damaging agents in a human ovarian cancer cell line
-
Vikhanskaya F, Marchini S, Marabese M, Galliera E, Broggini M. P73a overexpression is associated with resistance to treatment with DNA-damaging agents in a human ovarian cancer cell line. Cancer Res 2001;61:935-8.
-
(2001)
Cancer Res
, vol.61
, pp. 935-938
-
-
Vikhanskaya, F.1
Marchini, S.2
Marabese, M.3
Galliera, E.4
Broggini, M.5
|