Glucose increases endothelial-dependent superoxide formation in coronary arteries by NAD(P)H oxidase activation: Attenuation by the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor atorvastatin

Diabetes

Volumn 51, Issue 8, 2002, Pages 2648-2652

  Christ, Michael ^a,b   Bauersachs, Johann ^c   Liebetrau, Claudia ^c   Heck, Marina ^a   Günther, Andreas ^a   Wehling, Martin ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MESSENGER RNA; MEVALONIC ACID; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUCROSE; SUPEROXIDE;

ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; SWINE; VASCULAR ENDOTHELIUM;

EID: 0036321078     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.51.8.2648     Document Type: Article

References (22)

1. Oxidative stress and diabetic vascular complications
2. Pathophysiology of oxidative stress in diabetes mellitus
3. High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H(2) receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells
4. p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats
5. p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells
6. Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II
7. Expression of phagocyte NADPH oxidase components in human endothelial cells
8. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
9. Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction: Role of vascular superoxide anion formation and endothelial nitric oxide synthase expression
10. Rapid colorimetric assay for cell growth and survival: Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
11. Aldosterone, not estradiol, is the physiological agonist for rapid increases in cAMP in vascular smooth muscle cells
12. Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: Role of enhanced vascular superoxide production
13. Pulsatile stretch stimulates superoxide production and activates nuclear factor-kappa B in human coronary smooth muscle
14. Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes
15. Expression of NADH/NADPH oxidase p22phox in human coronary arteries
16. Protein kinase C activation and the development of diabetic complications
17. Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells
18. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
19. Direct vascular effects of HMG-CoA reductase inhibitors
20. Effect of lovastatin on small GTP binding proteins and on TGF-beta1 and fibronectin expression
21. Effect of statin therapy on C-reactive protein levels: The pravastatin inflammation/CRP evaluation (PRINCE): A randomized trial and cohort study
22. Statin therapy, lipid levels, C-reactive protein and the survival of patients with angiographically severe coronary artery disease