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Volumn 298, Issue 1-2, 2008, Pages 33-38

Structural requirements for uptake and recognition of CpG oligonucleotides

Author keywords

Adjuvant; CpG DNA; Dendritic cells; Epigenetic; IL 12

Indexed keywords

BACTERIAL DNA; CPG OLIGODEOXYNUCLEOTIDE; DOUBLE STRANDED DNA; IMMUNOLOGICAL ADJUVANT; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12P40; PATTERN RECOGNITION RECEPTOR; SINGLE STRANDED DNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9;

EID: 36749081174     PISSN: 14384221     EISSN: 16180607     Source Type: Journal    
DOI: 10.1016/j.ijmm.2007.07.007     Document Type: Short Survey
Times cited : (44)

References (30)
  • 1
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira S., and Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol. Lett. 85 (2003) 85-95
    • (2003) Immunol. Lett. , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 2
    • 1642527864 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) selective nucleosomal remodeling at the IL-12p40 promoter
    • Albrecht I., Tapmeier T., Zimmermann S., Frey M., Heeg K., and Dalpke A. Toll-like receptor (TLR) selective nucleosomal remodeling at the IL-12p40 promoter. EMBO Rep 5 (2004) 172-177
    • (2004) EMBO Rep , vol.5 , pp. 172-177
    • Albrecht, I.1    Tapmeier, T.2    Zimmermann, S.3    Frey, M.4    Heeg, K.5    Dalpke, A.6
  • 3
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of TLR9 prevents recognition of self DNA but facilitates access to viral DNA
    • Barton G.M., Kagan J.C., and Medzhitov R. Intracellular localization of TLR9 prevents recognition of self DNA but facilitates access to viral DNA. Nat. Immunol. 7 (2006) 49-56
    • (2006) Nat. Immunol. , vol.7 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 4
    • 8644242379 scopus 로고    scopus 로고
    • Poly-guanosine strings improve cellular uptake and stimulatory activity of phosphodiester CpG oligonucleotides in human leukocytes
    • Bartz H., Mendoza Y., Gebker M., Fischborn T., Heeg K., and Dalpke A. Poly-guanosine strings improve cellular uptake and stimulatory activity of phosphodiester CpG oligonucleotides in human leukocytes. Vaccine 23 (2004) 148-155
    • (2004) Vaccine , vol.23 , pp. 148-155
    • Bartz, H.1    Mendoza, Y.2    Gebker, M.3    Fischborn, T.4    Heeg, K.5    Dalpke, A.6
  • 9
    • 6044242049 scopus 로고    scopus 로고
    • CpG DNA as immune response modifier
    • Dalpke A., and Heeg K. CpG DNA as immune response modifier. Int. J. Med. Microbiol. 294 (2004) 345-354
    • (2004) Int. J. Med. Microbiol. , vol.294 , pp. 345-354
    • Dalpke, A.1    Heeg, K.2
  • 10
    • 0035712854 scopus 로고    scopus 로고
    • CpG oligonucleotides in vaccination: signaling and mechanisms of action
    • Dalpke A., Zimmermann S., and Heeg K. CpG oligonucleotides in vaccination: signaling and mechanisms of action. Immunobiology 204 (2001) 667-676
    • (2001) Immunobiology , vol.204 , pp. 667-676
    • Dalpke, A.1    Zimmermann, S.2    Heeg, K.3
  • 11
    • 0036242206 scopus 로고    scopus 로고
    • Phosphodiester CpG oligonucleotides as adjuvants: Poly-guanosine runs enhance cellular uptake and improve immunostimulative activity of phosphodiester CpG oligonucleotides in vitro and in vivo
    • Dalpke A., Zimmermann S., Albrecht I., and Heeg K. Phosphodiester CpG oligonucleotides as adjuvants: Poly-guanosine runs enhance cellular uptake and improve immunostimulative activity of phosphodiester CpG oligonucleotides in vitro and in vivo. Immunology 106 (2002) 102-112
    • (2002) Immunology , vol.106 , pp. 102-112
    • Dalpke, A.1    Zimmermann, S.2    Albrecht, I.3    Heeg, K.4
  • 12
    • 0036917474 scopus 로고    scopus 로고
    • CpG-DNA in the prevention and treatment of infections
    • Dalpke A., Zimmermann S., and Heeg K. CpG-DNA in the prevention and treatment of infections. BioDrugs 16 (2002) 419-431
    • (2002) BioDrugs , vol.16 , pp. 419-431
    • Dalpke, A.1    Zimmermann, S.2    Heeg, K.3
  • 13
    • 0036803563 scopus 로고    scopus 로고
    • Immunopharmacology of CpG DNA
    • Dalpke A., Zimmermann S., and Heeg K. Immunopharmacology of CpG DNA. Biol. Chem. 383 (2002) 1491-1500
    • (2002) Biol. Chem. , vol.383 , pp. 1491-1500
    • Dalpke, A.1    Zimmermann, S.2    Heeg, K.3
  • 14
    • 33845905223 scopus 로고    scopus 로고
    • Adjuvant-enhanced antibody responses in the absence of Toll-like receptor signaling
    • Gavin A.L., Hoebe K., Duong B., Ota T., Martin C., Beutler B., and Nemazee D. Adjuvant-enhanced antibody responses in the absence of Toll-like receptor signaling. Science 314 (2006) 1936-1938
    • (2006) Science , vol.314 , pp. 1936-1938
    • Gavin, A.L.1    Hoebe, K.2    Duong, B.3    Ota, T.4    Martin, C.5    Beutler, B.6    Nemazee, D.7
  • 15
    • 36749097758 scopus 로고    scopus 로고
    • Immunostimulatory CpG oligonucleotides form defined three-dimensional structures: results from an NMR study
    • He G., Patra A., Siegmund K., Peter M., Heeg K., Dalpke A., and Richert C. Immunostimulatory CpG oligonucleotides form defined three-dimensional structures: results from an NMR study. Chem. Med. Chem 2 (2007) 549-560
    • (2007) Chem. Med. Chem , vol.2 , pp. 549-560
    • He, G.1    Patra, A.2    Siegmund, K.3    Peter, M.4    Heeg, K.5    Dalpke, A.6    Richert, C.7
  • 17
    • 33846194125 scopus 로고    scopus 로고
    • Innate immunity - cross-talk with adaptive immunity through pattern recognition receptors and cytokines
    • Kabelitz D., and Medzhitov R. Innate immunity - cross-talk with adaptive immunity through pattern recognition receptors and cytokines. Curr. Opin. Immunol. 19 (2007) 1-3
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 1-3
    • Kabelitz, D.1    Medzhitov, R.2
  • 18
    • 0038330766 scopus 로고    scopus 로고
    • CpG DNA as a vaccine adjuvant
    • Klinman D.M. CpG DNA as a vaccine adjuvant. Expert Rev. Vaccines 2 (2003) 305-315
    • (2003) Expert Rev. Vaccines , vol.2 , pp. 305-315
    • Klinman, D.M.1
  • 19
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • Krieg A.M. Therapeutic potential of Toll-like receptor 9 activation. Nat. Rev. Drug Discov. 5 (2006) 471-484
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 471-484
    • Krieg, A.M.1
  • 20
    • 0030850462 scopus 로고    scopus 로고
    • CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants
    • Lipford G.B., Bauer M., Blank C., Reiter R., Wagner H., and Heeg K. CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants. Eur. J. Immunol. 27 (1997) 2340-2344
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2340-2344
    • Lipford, G.B.1    Bauer, M.2    Blank, C.3    Reiter, R.4    Wagner, H.5    Heeg, K.6
  • 21
    • 0033806950 scopus 로고    scopus 로고
    • Poly-guanosine motifs costimulate antigen reactive CD8T cells while bacterial CpG-DNA affect T-cell activation via antigen-presenting cell-derived cytokines
    • Lipford G.B., Bendigs S., Heeg K., and Wagner H. Poly-guanosine motifs costimulate antigen reactive CD8T cells while bacterial CpG-DNA affect T-cell activation via antigen-presenting cell-derived cytokines. Immunology 101 (2000) 46-52
    • (2000) Immunology , vol.101 , pp. 46-52
    • Lipford, G.B.1    Bendigs, S.2    Heeg, K.3    Wagner, H.4
  • 22
    • 0031050034 scopus 로고    scopus 로고
    • Innate immunity: impact on the adaptive immune response
    • Medzhitov R., and Janeway C.A. Innate immunity: impact on the adaptive immune response. Curr. Opin. Immunol. 9 (1997) 4-9
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 4-9
    • Medzhitov, R.1    Janeway, C.A.2
  • 23
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: the virtues of a nonclonal system of recognition
    • Medzhitov R., and Janeway C.A. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91 (1997) 295-298
    • (1997) Cell , vol.91 , pp. 295-298
    • Medzhitov, R.1    Janeway, C.A.2
  • 24
    • 0242267902 scopus 로고    scopus 로고
    • CpG oligonucleotides with modified termini and nicked dumbbell structure show enhanced immunostimulaty activity
    • Narayanan S., Dalpke A.H., Siegmund K., Heeg K., and Richert C. CpG oligonucleotides with modified termini and nicked dumbbell structure show enhanced immunostimulaty activity. J. Med. Chem. 46 (2003) 5031-5044
    • (2003) J. Med. Chem. , vol.46 , pp. 5031-5044
    • Narayanan, S.1    Dalpke, A.H.2    Siegmund, K.3    Heeg, K.4    Richert, C.5
  • 25
    • 0026091287 scopus 로고
    • Efficiency of peptides and lipopeptides for in vivo priming of virus-specific cytotoxic T cells
    • Schild H., Deres K., Wiesmüller K.H., Jung G., and Rammensee H.G. Efficiency of peptides and lipopeptides for in vivo priming of virus-specific cytotoxic T cells. Eur. J. Immunol. 21 (1991) 2649-2654
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2649-2654
    • Schild, H.1    Deres, K.2    Wiesmüller, K.H.3    Jung, G.4    Rammensee, H.G.5
  • 27
    • 0035213770 scopus 로고    scopus 로고
    • Muramyl dipeptide-Lys stimulates the function of human dendritic cells
    • Todate A., Suda T., Kuwata H., Chida K., and Nakamura H. Muramyl dipeptide-Lys stimulates the function of human dendritic cells. J. Leukoc. Biol. 70 (2001) 723-729
    • (2001) J. Leukoc. Biol. , vol.70 , pp. 723-729
    • Todate, A.1    Suda, T.2    Kuwata, H.3    Chida, K.4    Nakamura, H.5
  • 28
    • 2942679083 scopus 로고    scopus 로고
    • The immunobiology of the TLR9 subfamily
    • Wagner H. The immunobiology of the TLR9 subfamily. Trends Immunol 25 (2004) 381-386
    • (2004) Trends Immunol , vol.25 , pp. 381-386
    • Wagner, H.1
  • 29
    • 0032521881 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis
    • Zimmermann S., Egeter O., Hausmann S., Lipford G.B., Röcken M., Wagner H., and Heeg K. CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J. Immunol. 160 (1998) 3627-3630
    • (1998) J. Immunol. , vol.160 , pp. 3627-3630
    • Zimmermann, S.1    Egeter, O.2    Hausmann, S.3    Lipford, G.B.4    Röcken, M.5    Wagner, H.6    Heeg, K.7
  • 30
    • 0037435890 scopus 로고    scopus 로고
    • Immunostimulatory DNA as adjuvants: efficacy of phosphodiester CpG oligonucleotides is enhanced by 5′ sequence modifications
    • Zimmermann S., Dalpke A., and Heeg K. Immunostimulatory DNA as adjuvants: efficacy of phosphodiester CpG oligonucleotides is enhanced by 5′ sequence modifications. Vaccine 21 (2003) 990-995
    • (2003) Vaccine , vol.21 , pp. 990-995
    • Zimmermann, S.1    Dalpke, A.2    Heeg, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.