Immunostimulatory DNA as adjuvant: Efficacy of phosphodiester CpG oligonucleotides is enhanced by 3′ sequence modifications

Vaccine

Volumn 21, Issue 9-10, 2003, Pages 990-995

  Zimmermann, Stefan ^a   Heeg, Klaus ^a   Dalpke, Alexander ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

CpG oligonucleotides; Immunostimulatory DNA; Vaccination adjuvant

Indexed keywords

GUANOSINE DERIVATIVE; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; INTERLEUKIN 12; INTERLEUKIN 6; NITRITE; OLIGONUCLEOTIDE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; CPG ISLAND; CYTOKINE RELEASE; DRUG ACTIVITY; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; FEMALE; IMMUNE RESPONSE; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; LEISHMANIASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SPLEEN CELL; SUPPLEMENTATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BASE SEQUENCE; CELL LINE; CYTOKINES; FEMALE; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGES; MICE; MICE, INBRED BALB C; NITRIC OXIDE; OLIGODEOXYRIBONUCLEOTIDES; SPLEEN;

EID: 0037435890     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(02)00550-9     Document Type: Conference Paper

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