Approaches to acrylamide physiologically based toxicokinetic modeling for exploring child-adult dosimetry differences

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 70, Issue 24, 2007, Pages 2033-2055

  Walker, Katherine ^a   Hattis, Dale ^a   Russ, Abel ^a   Sonawane, Bob ^b   Ginsberg, Gary ^c  

^a CLARK UNIVERSITY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c CDC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLAMIDE; CYTOCHROME P450 2E1; DNA; EPOXIDE HYDROLASE; GLUTATHIONE; GLYCIDAMIDE;

AREA UNDER THE CURVE; ARTICLE; CALIBRATION; DNA ADDUCT; DOSIMETRY; LIVER MICROSOME METABOLISM; METABOLIC CAPACITY; MONTE CARLO METHOD; PRIORITY JOURNAL; TOXICOKINETICS;

ACRYLAMIDE; ADOLESCENT; ADULT; ANIMALS; CHILD; CHILD, PRESCHOOL; CYTOCHROME P-450 CYP2E1; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOXIDE HYDROLASES; EPOXY COMPOUNDS; FOOD CONTAMINATION; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; INFANT; INFANT, NEWBORN; LIVER; MODELS, BIOLOGICAL; MONTE CARLO METHOD; RATS;

RATTUS;

EID: 36749060059     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390701601202     Document Type: Article

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