Physiological modeling of butadiene disposition in mice and rats

Chemico-Biological Interactions

Volumn 135-136, Issue , 2001, Pages 285-301

  Kohn, Michael C ^a   Melnick, Ronald L ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Butadiene; Enzymatic channeling; Metabolic mechanisms; PBPK modeling

Indexed keywords

1,2 EPOXY 3 BUTENE; 1,3 BUTADIENE; 3,4 EPOXYBUTANE 1,2 DIOL; BUTADIENE DIEPOXIDE; CYTOCHROME P450; EPOXIDE HYDROLASE; UNCLASSIFIED DRUG;

BLOOD LEVEL; CONFERENCE PAPER; DETOXIFICATION; DNA ADDUCT; ENDOPLASMIC RETICULUM; EXPERIMENTAL MODEL; INHALATION; STEADY STATE; TOXICOKINETICS;

ANIMALS; BUTADIENES; CYTOCHROME P-450 ENZYME SYSTEM; DNA ADDUCTS; EPOXIDE HYDROLASES; EPOXY COMPOUNDS; KINETICS; MALE; MICE; MODELS, BIOLOGICAL; OXIDATION-REDUCTION; RATS; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0035369313     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(01)00176-4     Document Type: Conference Paper

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