Salmonella efficiently enter and survive within cultured CD11c+ dendritic cells initiating cytokine expression

European Journal of Immunology

Volumn 29, Issue 4, 1999, Pages 1107-1115

  Marriott, Ian ^a   Hammond, Timothy G ^b   Thomas, Elaine K ^c   Bost, Kenneth L ^a  

^a UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c AMGEN INC   (United States)

Author keywords

Cellular activation; Cytokine; Dendritic cell; Infectious immunity bacteria; Rodent

Indexed keywords

ANTIBODY; CD11 ANTIGEN; CD8 ANTIGEN; CYTOKINE; FLT3 LIGAND; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CELL POPULATION; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FLUORESCENCE ACTIVATED CELL SORTER; HOST CELL; HUMAN; IMMUNE RESPONSE; IN VIVO STUDY; INTERNALIZATION; MACROPHAGE; MAGNET; MUCOSA; PEYER PATCH; PRIORITY JOURNAL; SALMONELLA; SALMONELLA DUBLIN; SURVIVAL;

EID: 0032932839     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199904)29:04<1107::AID-IMMU1107>3.0.CO;2-0     Document Type: Article

References (34)

1. Maier, T. and Oels, H. C., Role of the macrophage in natural resistance to salmonellosis in mice. Infect. Immun. 1972. 6: 438-443.
2. Jones, B. D., Host responses to pathogenic Salmonella infection. Genes Dev. 1997. 11: 679-687.
3. Finlay, B. B., Molecular and cellular mechanisms of Salmonella pathogenesis. Curr. Top. Microbiol. Immunol. 1994. 192: 163-185.
4. Kelsall, B. L. and Strober, W., Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patch. J. Exp. Med. 1996. 183: 237-247.
5. Pavli, P., Woodhams, C. E., Doe, W. F. and Hume, D. A., Isolation and characterization of antigen-presenting dendritic cells from the mouse intestinal lamina propria. Immunology 1990. 70: 40-47.
6. + dendritic cell population in mouse Peyer's patches. Eur. J. Immunol. 1996. 26: 1801-1806.
7. McWilliam, A. S., Nelson, D., Thomas, J. A. and Holt, P. G., Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces. J. Exp. Med. 1994. 179: 1331-1336.
8. Sousa, C. R., Hieny, S., Scharton-Kersten, T., Jankovic, D., Charest, H., Germain, R. N. and Sher, A., In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas [see comments]. J. Exp. Med. 1997. 186: 1819-1829.
9. Austyn, J. M., New insights into the mobilization and phagocytic activity of dendritic cells [comment]. J. Exp. Med. 1996. 183: 1287-1292.
10. Filgueira, L., Nestle, F. O., Rittig, M., Joller, H. I. and Groscurth, P., Human dendritic cells phagocytose and process Borrelia burgdorferi. J. Immunol. 1996. 157: 2998-3005.
11. Guzman, C. A., Rohde, M., Bock, M. and Timmis, T., Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells. Infect. Immun. 1994. 62: 5528-5537.
12. Henderson, R. A., Watkins, S. C. and Flynn, J. L., Activation of human dendritic cells following infection with Mycobacterium tuberculosis. J. Immunol. 1997. 159: 635-643.
13. Inaba, K., Inaba, M., Naito, M. and Steinman, R. M., Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo. J. Exp. Med. 1993. 178: 479-488.
14. Leenen, P. J., Radosevic, K., Voerman, J. S., Salomon, B., van Rooijen, N., Klatzmann, D. and van Ewijk, W., Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnover. J. Immunol. 1998. 160: 2166-2173.
15. Matsuno, K., Ezaki, T., Kudo, S. and Uehara, Y., A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph [see comments]. J. Exp. Med. 1996. 183: 1865-1878.
16. Reis e Sousa, C., Stahl, P. D. and Austyn, J. M., Phagocytosis of antigens by Langerhans cells in vitro. J. Exp. Med. 1993. 178: 509-519.
17. Cella, M., Sallusto, F. and Lanzavecchia, A., Origin, maturation and antigen presenting function of dendritic cells. Curr. Opin. Immunol. 1997. 9: 10-16.
18. Steinman, R. M., The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 1991. 9: 271-296.
19. Winzler, C., Rovere, P., Rescigno, M., Granucci, F., Penna, G., Adorini, L., Zimmermann, V. S., Davoust, J. and Ricciardi-Castagnoli, P., Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J. Exp. Med. 1997. 185: 317-328.
20. + T cells. J. Immunol. 1995. 154: 5071-5079.
21. Koch, F., Stanzl, U., Jennewein, P., Janke, K., Heufler, C., Kampgen, E., Romani, N. and Schuler, G., High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and down-regulation by IL-4 and IL-10 [published erratum appears in J Exp Med 1996 Oct 1; 184(4): following 1590]. J. Exp. Med. 1996. 184: 741-746.
22. Heufler, C., Koch, F., Stanzl, U., Topar, G., Wysocka, M., Trinchieri, G., Enk, A., Steinman, R. M., Romani, N. and Schuler, G., Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells. Eur. J. Immunol. 1996. 26: 659-668.
23. Cella, M., Scheidegger, D., Palmer-Lehmann, K., Lane, P., Lanzavecchia, A. and Alber, G., Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 1996. 184: 747-752.
24. Drakes, M. L., Lu, L., Subbotin, V. M. and Thomson, A. W., In vivo administration of ftl3 ligand markedly stimulates generation of dendritic cell progenitors from mouse liver. J. Immunol. 1997. 159: 4268-4278.
25. Maraskovsky, E., Brasel, K., Teepe, M., Roux, E. R., Lyman, S. D., Shortman, K. and McKenna, H. J., Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. J. Exp. Med. 1996. 184: 1953-1962.
26. Pulendran, B., Lingappa, J., Kennedy, M. K., Smith, J., Teepe, M., Rudensky, A., Maliszewski, C. R. and Maraskovsky, E., Development pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice. J. Immunol. 1997. 159: 2222-2231.
27. Shurin, M.R., Pandharipande, P. P., Zorina, T. D., Haluszczak, C., Subbotin, V. M., Hunter, O., Brumfield, A., Storkus, W. J., Maraskovsky, E. and Lotze, M. T., FLT3 ligand induces the generation of functionally active dendritic cells in mice. Cell. Immunol. 1997. 179: 174-184.
28. Williams, D. E., In vivo effects of flt3 ligand [letter]. Blood 1997. 90: 5022.
29. Bost, K. L. and Clements, J. D., Intracellular Salmonella dublin induces substantial secretion of the 40-kilodalton subunit of interleukin-12 (IL-12) but minimal secretion of IL-12 as a 70-kilodalton protein in murine macrophages. Infect. Immun. 1997. 65: 3186-3192.
30. Elsinghorst, E. A., Measurement of invasion by gentamicin resistance. Methods Enzymol. 1994. 236: 405-420.
31. Kincy-Cain, T. and Bost, K. L., Increased susceptibility of mice to Salmonella infection following in vivo treatment with the substance P antagonist, spantide II. J. Immunol. 1996. 157: 255-264.
32. Bost, K. L., Bieligk, S. C. and Jaffe, B. M., Lymphokine mRNA expression by transplantable murine B lymphocytic malignancies. Tumor-derived IL-10 as a possible mechanism for modulating the anti-tumor response. J. Immunol. 1995. 154: 718-729.
33. Bost, K. L. and Clements, J. D., In vivo induction of interleukin-12 mRNA expression after oral immunization with Salmonella dublin or the B subunit of Escherichia coli heat-labile enterotoxin. Infect. Immun. 1995. 63: 1076-1083.
34. Bost, K. L. and Mason, M. J., Thapsigargin and cyclopiazonic acid initiate rapid and dramatic increases of IL-6 mRNA expression and IL-6 secretion in murine peritoneal macrophages. J. Immunol. 1995. 155: 285-296.