pH regulated scavenging activity of beer antioxidants through modified DPPH assay

Toxicology and Industrial Health

Volumn 23, Issue 2, 2007, Pages 75-81

  Singh, Neetu ^a   Sharma, Ramesh ^a   Balapure, Anil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

antioxidants; ascorbic acid; beer; DPPH; pH; scavenging activity

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ALCOHOL; ANTIOXIDANT; ASCORBIC ACID; SCAVENGER;

ANTIOXIDANT ACTIVITY; ARTICLE; BEER; PH; QUANTITATIVE ASSAY;

ANTIOXIDANTS; BEER; CHEMISTRY, ANALYTICAL; FREE RADICAL SCAVENGERS; FREE RADICALS; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; PICRATES;

EID: 36348975683     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/0748233707077429     Document Type: Article

References (46)

1. Halliwell, B. and Gutteridge, J.M.C. 1999: Free radicals in biology and medicine, Clarendon Press.
2. Rice-Evans, C.A. ed. 2000: Wake up to flavonoids, Royal Society of Medicine International Congress and Symposium Series. RSM Press.
3. Andersen, M.L., Outtrup, H. and Skibsted, L.H. 2000: Potential antioxidants in beer assessed by ESR spin trapping. J Agric Food Chem 483, 106—11.
4. Miranda, C.L., Stevens, J.F., Ivanov, V., McCall, M., Frei, B., Deinzer, M.L. and Buhler, D.R. 2000a: Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro. J Agric Food Chem 48, 3876—84.
5. Stevens, J.F., Taylor, A.W. and Deinzer, M.L. 1999: Quantitative analysis of xanthohumol and related flavonoids in hops and beer by liquid chromatography-tandem mass spectrometry. J Chromatogr A832, 97—107.
6. Wohlfart, R. Humulus. In Hänsel, R. Keller, K. Rimpler, H. and Schneider, G. eds. Hagers Handbuch der Pharmazeutischen Praxis (volume 5). Springer, 47—458.
7. Stevens, J.F., Miranda, C.L., Buhler, D.R. and Deinzer, M.L. Chemistry and biology of hop flavonoids. J Am Soc Brew Chem 56, 136—45.
8. Hopfenzapfen, Lupuli flos. 2000: In Europä isches Arzneibuch, Nachtrag 2000, Deutsche Ausgabe, Deutscher Apotheker-Verlag, Stuttgart: Govi-Verlag - Pharmazeutischer Verlag GmbH Eschborn.
9. Gerhauser, C., Alt, A., Heiss, E., Gamal-Eldeen, A., Klimo, K., Knauft, J., Neumann, I., Scherf, H.-R., Frank, N., Bartsch, H. and Becker, H. 2002: Cancer chemopreventive activity of xanthohumol, a natural product derived from hop. Mol Canc Therapeut 1, 959—69.
10. Henderson, M.C., Miranda, C.L., Stevens, J.F., Deinzer, M.L. and Buhler, D.R. 2000: In vitro inhibition of human P450 enzymes by prenylated flavonoids from hop, Humulus lupulus. Xenobiotica 30, 235—51.
11. Miranda, C.L., Aponso, G.L., Stevens, J.F., Deinzer, M.L. and Buhler, D.R. 2000b: Prenylated chalcones and flavanones as inducers of quinine reductase in mouse Hepa 1c1c7 cells, Cancer Lett 149, 21—29.
12. Milligan, S.R., Kalita, J.C., Pocock, V., Van De Kauter, V., Stevens, J.F., Deinzer, M.L., Rong, H. and De Keukeleire, D. 2000: The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids. J Clin Endol Metab 85, 4912—15.
13. Anonymous. 1996: Good news for beer drinkers. Science 274, 1309—10.
14. Arimoto-Kobayashi, S., Sugiyama, C., Harada, N., Takeuchi, M., Takemura, M. and Hayatsu, H.J. 1999: Inhibitory effects of beer and other alcoholic beverages on mutagenesis and DNA adduct formation induced by several carcinogens. Agric Food Chem 47, 221—30.
15. Kimura, S., Hayatsu, H. and Arimoto-Kobayashi, S. 1999: Glycine betaine in beer as an antimutagenic substance against 2-chloro-4-methylthiobutanoic acid, the sanma-fish mutagen. Mutat Res 439, 267—76.
16. Miranda, C.L., Stevens, J.F., Ivanov, V., McCall, M., Frei, B., Deinzer, M.L. and Buhler, D.R. 2000c: Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro. J Agric Food Chem 48, 3876—84.
17. Miranda, C.L., Stevens, J.F., Helmrich, A., Henderson, M.C., Rodriguez, R.J., Yang, Y.H., Deinzer, M.L., Barnes, D.W. and Buhler, D.R. 1999: Antiproliferative and cytotoxic effects of prenylated flavonoids from hop (Humulus lupulus) in human cancer cell lines. Food Chem Toxicol 37, 271—85.
18. West, E.S., Todd, W.R., Mason, H.S. and Van Bruggen, J.T. 1967: Text book of biochemistry, (fourth edition). The Macmillan Company, Collier-Macmillan Canada, Ltd.
19. Jourd'heuil, D., Morise, Z., Conner, E.M. and Grisham, M.B. 1997: Oxidants, transcription factors and intestinal inflammation. J Clin Gastroenterol 25, S61—72.
20. Inoue, M., Nishikawa, M., Sato, E.F., Ah-Mee, P., Kashiba, M., Takehara, Y. and Utsumi, K. 1999: Cross-talk of NO, super-oxide and molecular oxygen, a majesty of aerobic life. Free Radic Res 31, 251—60.
21. Ames, B.N. 1989: Mutagenesis and carcinogenesis: endogenous and exogenous factors. Environ Mol Mutagen 14, S66-77.
22. Waring, A.J., Drake, I.M., Scorah, C.J., White, K.L., Lynch, D.A., Axon, A.T. and Dixon, M.F. 1996: Ascorbic and total vitamin C concentrations in plasma, gastric juice and gastrointestinal mucosa: effects of gastritis and oral supplementation. Gut 38, 171—76.
23. Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. 1994: The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. New England Journal of Medicine 330, 1029—35.
24. Blois, M.S. 1958: Antioxidant determinations by the use of a stable free radical. Nature 181, 1199—200.
25. Sánchez-Moreno, C. 2002: Review: methods used to evaluate the free radical scavenging activity in foods and biological systems. Food Sci Tech Int 8, 121—37.
26. Schwarz, K., Bertelsen, G., Nissen, L.R., Gardner, P.T., Heinonen, M.I., Hopia, A., Huynh-Ba, T., Lambelet, P., McPhail, D., Skibsted, L.H. and Tijburg, L. 2001: Investigation of plant extracts for the protection of processed foods against lipid oxidation. Comparison of antioxidant assays based on radical scavenging, lipid oxidation and analysis of the principal antioxidant compounds. Eur Food Res Technol 212, 319—28.
27. Kim, J.-K., Noh, J.H., Lee, S., Choi, J.S. Suh, H., Chung, H.Y., Song, Y.-O. and Choi, W.C. 2002: The first total synthesis of 2,3,6-tribromo-4,5-dihydroxybenzyl methyl ether (TDB) and its antioxidant activity. Bull Korean Chem Soc 23, 661—62.
28. Molyneux, P. 2004: The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin J Sci Technol 26, 211—19.
29. Brand-Williams, W., Cuvelier, M.E., Berset C. 1995: Use of a free radical method to evaluate antioxidant activity. Lebensmittel-Wissenschaft und Technologie 28, 25—30.
30. Lu, Y. and Foo, L.Y. 2000: Antioxidant and radical scavenging activities of polyphenols from apple pomace. Food Chemistry 68, 81—85.
31. Sánchez-Moreno, C., Larrauri, J.A. and Saura-Calixto, F. New- parameter for evaluation of free radical scavenging capacity of polyphenols, 2nd International Electronic Conference on Synthetic Organic Chemistry (ESCOC-2), http://www.mdpi.org/escoc/, 1—30 September 1998. [dp130];http://ecsoc2.hcc.ru/DP_TOP1/dp130/dp130.htm.
32. Sánchez-Moreno, C., Larrauri, J.A. and Saura-Calixto, F. 1999: Free radical scavenging capacity and inhibition of lipid oxidation of wines, grape juices and related polyphenolic constituents. Food Res Int 32, 407—12.
33. Guo, J.-T., Lee, H.-L., Chiang, S.-H., Lin, F.I. and Chang, C.-Y. 2001: Antioxidant properties of the extracts from different parts of broccoli in Taiwan. J Food Drug Anal 9, 96—101.
34. Bondet, V., Brand-Williams, W. and Berset, C. 1997: Kinetics and mechanisms of antioxidant activity using the DPPH free radical method. Lebensmittel-Wissenschaft und Technologie 30, 609—15.
35. Gómez-Alonso, S., Fregapane, G., Salvador, M.D. and Gordon, M.H. 2003: Changes in phenolic composition and antioxidant activity of virgin olive oil during frying. J Agric Food Chem 51, 667—72.
36. Lebeau, J., Furman, C., Bernier, J.-L., Duriez, P., Teissier, E. and Cotelle, N. 2000: Antioxidant properties of di-tert-butyl-hydroxylated flavonoids. Free Radic Biol Med 29, 900—12.
37. Zhu, Q.Y., Hackman, R.M., Ensunsa, J.L., Holt, R.R. and Keen, C.L. Antioxidative activities of oolong tea. J Agric Food Chem 50, 6929—34.
38. Leitão, G.G., Leitão, S.G. and Vilegas, W. 2002: Quick preparative separation of natural naphthoquinones with antioxidant activity by high-speed counter-current chromatography. Z Naturforsch 57c, 1051—55.
39. Yepez, B., Espinosa, M., López, S. and Bolãnos, G. 2002: Producing antioxidant fractions from herbaceous matrices by supercritical fluid extraction. Fluid Phase Equil 194—197, 879—884.
40. Llesuy, S., Evelson, P., Campos, A.M. and Lissi, E. 2001: Methodologies for evaluation of total antioxidant activities in complex mixtures. A critical review. Biol Res 34, 1—20.
41. Nielsen, I.L., Haren, G.R., Magnussen, E.L., Dragsted, L.O. and Rasmussen, S.E. 2003: Quantification of anthocyanins in commercial black currant juices by simple high-performance liquid chromatography: investigation of their pH stability and antioxidant potency. J Agric Food Chem 51, 5861—68.
42. Walle, T. 2004: Absorption and metabolism of flavonoids. Free Radic Biol Med 36, 829—37.
43. Struck, M., Watkins, T., Tomeo, A., Halley, J. and Bierenbaum, M. 1994: Effect of red and white wine on serum lipids, platelet aggregation, oxidation products and antioxidants: a preliminary report. Nutr Res 14, 1811—19.
44. Williams, R.J., Spencer, J.P.E. and Rice-Evans, C. 2004: Flavonoids: antioxidants or signaling molecules? Free Radic Biol Med 37, 287—303.
45. Webb, R.M. and Ebeler, E.S. 2004: Comparative analysis of topoisomerase IB inhibition and DNA intercalation by flavonoids and similar compounds: structural determinates of activity. Biochem J 384, 527—41.
46. Halliwell, B., Zhao, K. and Whiteman, M. 2000: The gastrointestinal tract: A major site of antioxidant action. Free Radic Res 33, 819—30.