HAP1 can sequester a subset of TBP in cytoplasmic inclusions via specific interaction with the conserved TBPCORE

BMC Molecular Biology

Volumn 8, Issue , 2007, Pages

  Prigge, Justin R ^a   Schmidt, Edward E ^a,b  

^a MONTANA STATE UNIVERSITY   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANDROGEN RECEPTOR; CYTOPLASM PROTEIN; HUNTINGTIN; HUNTINGTIN ASSOCIATED PROTEIN 1; POLYGLUTAMINE; TATA BINDING PROTEIN; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN; HAP1 PROTEIN, MOUSE; HUNTINGTON PROTEIN, MOUSE; HYBRID PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; PEPTIDE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL INCLUSION; CELL LOSS; CELL NUCLEUS; CELL STRAIN COS7; CELLULAR DISTRIBUTION; CEREBELLAR ATAXIA; CONTROLLED STUDY; DISEASE COURSE; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; KENNEDY DISEASE; MAMMAL CELL; MOLECULAR CLONING; NERVE CELL; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM; ANIMAL; CELL LINE; CHEMISTRY; CYTOPLASM; GENETIC TRANSFECTION; GENETICS; IMMUNOPRECIPITATION; METABOLISM; METHODOLOGY; MOUSE; PROTEIN BINDING; SPINOCEREBELLAR DEGENERATION;

MAMMALIA;

ANIMALS; APOPTOSIS; CELL LINE; CELL NUCLEUS; CYTOPLASM; GREEN FLUORESCENT PROTEINS; HUMANS; HUNTINGTON DISEASE; IMMUNOPRECIPITATION; INCLUSION BODIES; MICE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PROTEIN BINDING; RECEPTORS, ANDROGEN; RECOMBINANT FUSION PROTEINS; SPINOCEREBELLAR ATAXIAS; TATA-BOX BINDING PROTEIN; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 36348971109     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-8-76     Document Type: Article

References (63)

1. Everett CM Wood NW Trinucleotide repeats and neurodegenerative disease Brain 2004, 127(Pt 11):2385-2405. 10.1093/brain/awh278 15329351
2. MacDonald ME Ambrose CM Duyao MP Myers RH Lin C Srinidhi L Barnes G Taylor SA James M Groot N MacFarlane H Jenkins B Anderson MA Wexler NS Gusella JF Bates GP Baxendale S Hummerich H Kirby S North M Youngman S Mott R Zehetner G Sedlacek Z Poustka A Frischauf A-M Lehrach H Buckler AJ Church D Doucette-Stamm L A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group Cell 1993, 72(6):971-983. 10.1016/0092-8674(93)90585-E 8458085
3. Landles C Bates GP Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series EMBO Rep 2004, 5(10):958-963. 1299150 15459747 10.1038/sj.embor.7400250
4. Li SH Hosseini SH Gutekunst CA Hersch SM Ferrante RJ Li XJ A human HAP1 homologue. Cloning, expression, and interaction with huntingtin J Biol Chem 1998, 273(30):19220-19227. 10.1074/jbc.273.30.19220 9668110
5. Li XJ Li SH Sharp AH Nucifora FC Jr Schilling G Lanahan A Worley P Snyder SH Ross CA A huntingtin-associated protein enriched in brain with implications for pathology Nature 1995, 378(6555):398-402. 10.1038/ 378398a0 7477378
6. van Roon-Mom WM Reid SJ Faull RL Snell RG TATA-binding protein in neurodegenerative disease Neuroscience 2005, 133(4):863-872. 10.1016/ j.neuroscience.2005.03.024 15916858
7. Koide R Ikeuchi T Onodera O Tanaka H Igarashi S Endo K Takahashi H Kondo R Ishikawa A Hayashi T Saito M Tomoda A Miike T Naito H Ikuta F Tsuji S Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA) Nat Genet 1994, 6(1):9-13. 10.1038/ng0194-9 8136840
8. Nagafuchi S Yanagisawa H Sato K Shirayama T Ohsaki E Bundo M Takeda T Tadokoro K Kondo I Murayama N Tanaka Y Kikushima H Umino K Kurosawa H Furukawa T Nihei K Inoue T Sano A Komure O Takahashi M Yoshizawa T Kanazawa I Yamada M Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p Nat Genet 1994, 6(1):14-18. 10.1038/ng0194-14 8136826
9. La Spada AR Roling DB Harding AE Warner CL Spiegel R Hausmanowa-Petrusewicz I Yee WC Fischbeck KH Meiotic stability and genotype-phenotype correlation of the trinucleotide repeat in X-linked spinal and bulbar muscular atrophy Nat Genet 1992, 2(4):301-304. 10.1038/ ng1292-301 1303283
10. Li M Miwa S Kobayashi Y Merry DE Yamamoto M Tanaka F Doyu M Hashizume Y Fischbeck KH Sobue G Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy Ann Neurol 1998, 44(2):249-254. 10.1002/ana.410440216 9708548
11. Beitel LK Scanlon T Gottlieb B Trifiro MA Progress in Spinobulbar muscular atrophy research: Insights into neuronal dysfunction caused by the polyglutamineexpanded androgen receptor Neurotox Res 2005, 7(3):219-230. 15897156
12. Walling HW Baldassare JJ Westfall TC Molecular aspects of Huntington's disease J Neurosci Res 1998, 54(3):301-308. 10.1002/ (SICI)1097-4547(19981101)54:3<301::AID-JNR1>3.0.CO;2-W 9819135
13. Saudou F Finkbeiner S Devys D Greenberg ME Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions Cell 1998, 95(1):55-66. 10.1016/ S0092-8674(00)81782-1 9778247
14. Schaffar G Breuer P Boteva R Behrends C Tzvetkov N Strippel N Sakahira H Siegers K Hayer-Hartl M Hartl FU Cellular toxicity of polyglutamine expansion proteins: Mechanism of transcription factor deactivation Mol Cell 2004, 15(1):95-105. 10.1016/j.molcel.2004.06.029 15225551
15. Ciechanover A Brundin P The ubiquitin proteasome system in neurodegenerative diseases: Sometimes the chicken, sometimes the egg Neuron 2003, 40(2):427-446. 10.1016/S0896-6273(03)00606-8 14556719
16. Sakahira H Breuer P Hayer-Hartl MK Hartl FU Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity Proc Natl Acad Sci USA 2002, 99(Suppl 4):16412-16418. 139902 12189209 10.1073/ pnas.182426899
17. McCampbell A Taylor JP Taye AA Robitschek J Li M Walcott J Merry D Chai Y Paulson H Sobue G Fischbeck KH CREB-binding protein sequestration by expanded polyglutamine Hum Mol Genet 2000, 9(14):2197-2202. 10.1093/hmg/ 9.14.2197 10958659
18. Perez MK Paulson HL Pendse SJ Saionz SJ Bonini NM Pittman RN Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation J Cell Biol 1998, 143(6):1457-1470. 10.1083/jcb.143.6.1457 9852144
19. Hernandez N TBP, a universal eukaryotic transcription factor? Genes Dev 1993, 7(7B):1291-1308. 10.1101/gad.7.7b.1291 8330735
20. Nakamura K Jeong SY Uchihara T Anno M Nagashima K Nagashima T Ikeda S Tsuji S Kanazawa I SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein Hum Mol Genet 2001, 10(14):1441-1448. 10.1093/hmg/10.14.1441 11448935
21. Schmidt EE Schibler U High accumulation of components of the RNA polymerase II transcription machinery in rodent spermatids Development 1995, 121(8):2373-2383. 7671803
22. Schmidt EE Schibler U Cell size regulation, a mechanism that controls cellular RNA accumulation: Consequences on regulation of the ubiquitous transcription factors Oct1 and NF-Y and the liver-enriched transcription factor DBP J Cell Biol 1995, 128(4):467-483. 10.1083/jcb.128.4.467 7532171
23. Toyoshima Y Yamada M Onodera O Shimohata M Inenaga C Fujita N Morita M Tsuji S Takahashi H SCA17 homozygote showing Huntington's disease-like phenotype Ann Neurol 2004, 55(2):281-286. 10.1002/ana.10824 14755733
24. Li SH Yu ZX Li CL Nguyen HP Zhou YX Deng C Li XJ Lack of huntingtinassociated protein-1 causes neuronal death resembling hypothalamic degeneration in Huntington's disease J Neurosci 2003, 23(17):6956-6964. 12890790
25. Fujinaga R Kawano J Matsuzaki Y Kamei K Yanai A Sheng Z Tanaka M Nakahama K Nagano M Shinoda K Neuroanatomical distribution of Huntingtin-associated protein 1-mRNA in the male mouse brain J Comp Neurol 2004, 478(1):88-109. 10.1002/cne.20277 15334651
26. Zucker B Luthi-Carter R Kama JA Dunah AW Stern EA Fox JH Standaert DG Young AB Augood SJ Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: Neuronal selectivity and potential neuroprotective role of HAP1 Hum Mol Genet 2005, 14(2):179-189. 10.1093/hmg/ddi014 15548548
27. Takeshita Y Fujinaga R Zhao C Yanai A Shinoda K Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-ARinduced apoptosis Hum Mol Genet 2006, 15(15):2298-2312. 10.1093/hmg/ddl156 16782802
28. Li XJ Sharp AH Li SH Dawson TM Snyder SH Ross CA Huntingtin-associated protein (HAP1): Discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase Proc Natl Acad Sci USA 1996, 93(10):4839-4844. 39366 8643490 10.1073/pnas.93.10.4839
29. Page KJ Potter L Aronni S Everitt BJ Dunnett SB The expression of Huntingtinassociated protein (HAP1) mRNA in developing, adult and ageing rat CNS: Implications for Huntington's disease neuropathology Eur J Neurosci 1998, 10(5):1835-1845. 10.1046/j.1460-9568.1998.00185.x 9751154
30. Bertaux F Sharp AH Ross CA Lehrach H Bates GP Wanker E HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice FEBS Lett 1998, 426(2):229-232. 10.1016/S0014-5793(98)00352-4 9599014
31. Nasir J Duan K Nichol K Engelender S Ashworth R Colomer V Thomas S Disteche CM Hayden MR Ross CA Gene structure and map location of the murine homolog of the Huntington-associated protein, Hap1 Mamm Genome 1998, 9(7):565-570. 10.1007/s003359900819 9657855
32. Martin EJ Kim M Velier J Sapp E Lee HS Laforet G Won L Chase K Bhide PG Heller A Aronin N Difiglia M Analysis of Huntingtin-associated protein 1 in mouse brain and immortalized striatal neurons J Comp Neurol 1999, 403(4):421-430. 10.1002/ (SICI)1096-9861(19990125)403:4<421::AID-CNE1>3.0.CO;2-5 9888310
33. Li Y Chin LS Levey AI Li L Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking J Biol Chem 2002, 277(31):28212-28221. 10.1074/jbc.M111612200 12021262
34. Gutekunst CA Li SH Yi H Ferrante RJ Li XJ Hersch SM The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human J Neurosci 1998, 18(19):7674-7686. 9742138
35. Shinoda K Nagano M Osawa Y An aromatase-associated cytoplasmic inclusion, the "stigmoid body," in the rat brain: II. Ultrastructure (with a review of its history and nomenclature) J Comp Neurol 1993, 329(1):1-19. 10.1002/cne.903290102 8384220
36. Li SH Gutekunst CA Hersch SM Li XJ Association of HAP1 isoforms with a unique cytoplasmic structure J Neurochem 1998, 71(5):2178-2185. 9798945
37. Shen Y Kassavetis GA Bryant GO Berk AJ Polymerase (Pol) III TATA box-binding protein (TBP)-associated factor Brf binds to a surface on TBP also required for activated Pol II transcription Mol Cell Biol 1998, 18(3):1692-1700. 108884 9488486
38. Hertel KJ Maniatis T Serine-arginine (SR)-rich splicing factors have an exonindependent function in pre-mRNA splicing Proc Natl Acad Sci USA 1999, 96(6):2651-2655. 15823 10077565 10.1073/pnas.96.6.2651
39. Canaves JM Taylor SS Classification and phylogenetic analysis of the cAMPdependent protein kinase regulatory subunit family J Mol Evol 2002, 54(1):7-29. 10.1007/s00239-001-0013-1 11734894
40. Hori R Carey M Transcription: TRF walks the walk but can it talk the talk? Curr Biol 1998, 8(4):R124-127. 10.1016/S0960-9822(98)70987-X 9501975
41. Persengiev SP Zhu X Dixit BL Maston GA Kittler EL Green MR TRF3, a TATAbox-binding protein-related factor, is vertebrate-specific and widely expressed Proc Natl Acad Sci USA 2003, 100(25):14887-14891. 299843 14634207 10.1073/pnas.2036440100
42. Li XJ Li SH HAP1 and intracellular trafficking Trends Pharmacol Sci 2005, 26(1):1-3. 10.1016/j.tips.2004.11.001 15629196
43. Berti L Mittler G Przemeck GK Stelzer G Gunzler B Amati F Conti E Dallapiccola B Hrabe de Angelis M Novelli G Meisterernst M Isolation and characterization of a novel gene from the DiGeorge chromosomal region that encodes for a mediator subunit Genomics 2001, 74(3):320-332. 10.1006/geno.2001.6566 11414760
44. Thomas MC Chiang CM The general transcription machinery and general cofactors Crit Rev Biochem Mol Biol 2006, 41(3):105-178. 10.1080/ 10409230600648736 16858867
45. Lechner MS Levitan I Dressler GR PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin Nucleic Acids Res 2000, 28(14):2741-2751. 102659 10908331 10.1093/nar/ 28.14.2741
46. Sailer A MacDonald NJ Weissmann C Cloning and sequencing of the murine homologue of the human splicing factor U2AF65 Nucleic Acids Res 1992, 20(9):2374. 312357 1594454 10.1093/nar/20.9.2374
47. Zhang M Zamore PD Carmo-Fonseca M Lamond AI Green MR Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit Proc Natl Acad Sci USA 1992, 89(18):8769-8773. 50002 1388271 10.1073/pnas.89.18.8769
48. Li SH Li H Torre ER Li XJ Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth Mol Cell Neurosci 2000, 16(2):168-183. 10.1006/mcne.2000.0858 10924259
49. van Roon-Mom WM Reid SJ Jones AL MacDonald ME Faull RL Snell RG Insoluble TATA-binding protein accumulation in Huntington's disease cortex Brain Res Mol Brain Res 2002, 109(1-2):1-10. 10.1016/ S0169-328X(02)00450-3 12531510
50. Bondareva AA Schmidt EE Early vertebrate evolution of the TATA-binding protein, TBP Mol Biol Evol 2003, 20(11):1932-1939. 10.1093/molbev/msg205 12885957
51. Schmidt EE Davies CJ The origins of polypeptide domains Bioessays 2007, 29(3):262-270. 10.1002/bies.20546 17295290 1994825
52. Sumita K Makino Y Katoh K Kishimoto T Muramatsu M Mikoshiba K Tamura T Structure of a mammalian TBP (TATA-binding protein) gene: Isolation of the mouse TBP genome Nucleic Acids Res 1993, 21(11):2769. 309619 8332475 10.1093/nar/21.11.2769
53. Li SH Li XJ Huntingtin-protein interactions and the pathogenesis of Huntington's disease Trends Genet 2004, 20(3):146-154. 10.1016/ j.tig.2004.01.008 15036808
54. Li SH Gutekunst CA Hersch SM Li XJ Interaction of huntingtin-associated protein with dynactin P150Glued J Neurosci 1998, 18(4):1261-1269. 9454836
55. Colomer V Engelender S Sharp AH Duan K Cooper JK Lanahan A Lyford G Worley P Ross CA Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain Hum Mol Genet 1997, 6(9):1519-1525. 10.1093/hmg/6.9.1519 9285789
56. Kittler JT Thomas P Tretter V Bogdanov YD Haucke V Smart TG Moss SJ Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking Proc Natl Acad Sci USA 2004, 101(34):12736-12741. 515122 15310851 10.1073/pnas.0401860101
57. Marcora E Gowan K Lee JE Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2 Proc Natl Acad Sci USA 2003, 100(16):9578-9583. 170960 12881483 10.1073/pnas.1133382100
58. Gunther C von Hadeln K Muller-Thomsen T Alberici A Binetti G Hock C Nitsch RM Stoppe G Reiss J Gal A Finckh U Possible association of mitochondrial transcription factor A (TFAM) genotype with sporadic Alzheimer disease Neurosci Lett 2004, 369(3):219-223. 10.1016/ j.neulet.2004.07.070 15464268
59. Graveland GA Williams RS DiFiglia M Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease Science 1985, 227(4688):770-773. 10.1126/science.3155875 3155875
60. Ohbayashi T Schmidt EE Makino Y Kishimoto T Nabeshima Y Muramatsu M Tamura T Promoter structure of the mouse TATA-binding protein (TBP) gene Biochem Biophys Res Commun 1996, 225(1):275-280. 10.1006/bbrc.1996.1166 8769130
61. Prigge JR Schmidt EE Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP J Biol Chem 2006, 281(18):12260-12269. 10.1074/jbc.M510835200 16522640 2030495
62. Gietz RD Schiestl RH Willems AR Woods RA Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure Yeast 1995, 11(4):355-360. 10.1002/yea.320110408 7785336
63. Hoffman CS Winston F A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli Gene 1987, 57(2-3):267-272. 10.1016/0378-1119(87)90131-4 3319781