Protein geranylgeranyltransferase-I of Trypanosoma cruzi

Molecular and Biochemical Parasitology

Volumn 157, Issue 1, 2008, Pages 32-43

  Yokoyama, Kohei ^a   Gillespie, John R ^a   Van Voorhis, Wesley C ^a   Buckner, Frederick S ^a   Gelb, Michael H ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

CaaX motif; Chagas' disease; Prenylation; Protein farnesyltransferase; Protein geranylgeranyltransferase I; Trypanosoma cruzi

Indexed keywords

COMPLEMENTARY DNA; ENZYME INHIBITOR; GENOMIC DNA; GERANYLGERANYL PYROPHOSPHATE; GERANYLTRANSFERASE; GGTI 2151; GGTI 2154; GGTI 297; GGTI DU40; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN GERANYLGERANYLTRANSFERASE I; RECOMBINANT ENZYME; RNA; TETRAPEPTIDE; TRITIUM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BACULOVIRUS; BINDING SITE; CHAGAS DISEASE; CONTROLLED STUDY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME SUBSTRATE; ENZYME SUBUNIT; EPIMASTIGOTE; LIFE CYCLE; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PARASITE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRENYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; RAT; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE; VIRUS RECOMBINANT;

ALKYL AND ARYL TRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CLONING, MOLECULAR; CONSERVED SEQUENCE; CYTOSOL; DNA, PROTOZOAN; ENZYME INHIBITORS; ISOTOPE LABELING; MOLECULAR SEQUENCE DATA; POLYISOPRENYL PHOSPHATES; PROTEIN BINDING; PROTOZOAN PROTEINS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; TRITIUM; TRYPANOSOMA CRUZI;

EUKARYOTA; HEXAPODA; MAMMALIA; PROTOZOA; TRYPANOSOMA CRUZI;

EID: 36348947954     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2007.09.006     Document Type: Article

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