The DnaJ family of protein chaperones in Trypanosoma cruzi

Molecular and Biochemical Parasitology

Volumn 91, Issue 2, 1998, Pages

  Tibbetts, Randal S ^a,b   Jensen, Jennifer L ^a   Olson, Cheryl L ^a   Wang, Fred D ^a   Engman, David M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b MAYO CLINIC   (United States)

Author keywords

DnaJ; Heat shock protein; Molecular chaperone; Trypanosoma cruzi

Indexed keywords

CHAPERONE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 40; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; EPIMASTIGOTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MODIFICATION; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CLONING, MOLECULAR; GENES, PROTOZOAN; HEAT-SHOCK PROTEINS; HEAT-SHOCK RESPONSE; HSP40 HEAT-SHOCK PROTEINS; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; PROTOZOAN PROTEINS; SEQUENCE ALIGNMENT; TRYPANOSOMA CRUZI;

PROTOZOA; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0032520954     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00214-4     Document Type: Article

References (31)

1. [1] Craig EA, Gambill BD, Nelson RJ. Heat shock proteins: molecular chaperones of protein biogenesis. Microbiol Rev 1993;57:402-14.
2. [2] Hartl FU, Hlodan R, Langer T. Molecular chaperones in protein folding: the art of avoiding sticky situations. Trends Biochem Sci 1994;19:20-5.
3. [3] Cyr DM, Lu X, Douglas MG. Regulation of Hsp70 function by a eukaryotic DnaJ homolog. J Biol Chem 1992;267:20927-31.
4. [4] Cyr DM, Langer T, Douglas MG. DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70. Trends Biochem Sci 1994;19:176-81.
5. [5] Wawrzynow A, Zylicz M. Divergent effects of ATP on the binding of the DnaK and DnaJ chaperones to each other, or to their various native and denatured protein substrates. J Biol Chem 1995;270:19300-6.
6. [6] Schroder H, Langer T, Hartl FU, Bukau B. DnaK, DnaJ and GrpE form a cellular chaperone machinery capable of repairing heat-induced protein damage. EMBO J 1993;12:4137-44.
7. [7] Caplan AJ, Douglas MG. Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein. J Cell Biol 1991;114:609-21.
8. [8] Sadler I, Chiang A, Kurihara T, Rothblatt J, Way J, Silver P. A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein. J Cell Biol 1989;109:2665-75.
9. [9] Blumberg H, Silver PA. A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast. Nature 1991;349:627-30.
10. [10] Atencio DP, Yaffe MP. MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import. Mol Cell Biol 1992;12:283-91.
11. [11] Luke MM, Sutton A, Arndt KT. Characterization of SIS1, a Saccharomyces cerevisiae homologue of bacterial dnaJ proteins. J Cell Biol 1991;114:623-38.
12. [12] Mukai H, Shuntoh H, Chang CD, Asami M, Ueno M, Suzuki K, Kuno T. Isolation and characterization of CAJ1, a novel yeast homolog of dnaJ. Gene 1994;145:125-7.
13. [13] Rowley N, Prip-Buus C, Westermann B, Brown C, Schwarz E, Barrell B, Neupert W. Mdj1p, a novel chaperone of the dnaJ family, is involved in mitochondrial biogenesis and protein folding. Cell 1994;77:249-59.
14. [14] Caplan AJ, Cyr DM, Douglas MG. Eukaryotic homologues of Escherichia coli dnaJ: a diverse protein family that functions with hsp70 stress proteins. Mol Biol Cell 1993;4:555-63.
15. [15] Schwarz E, Westermann B, Caplan AJ, Ludwig G, Neupert W. XDJ1, a gene encoding a novel non-essential DnaJ homologue from Saccharomyces cerevisiae. Gene 1994;145:121-4.
16. [16] Silver PA, Way JC. Eukaryotic DnaJ homologs and the specificity of hsp70 activity. Cell 1993;74:5-6.
17. [17] Szabo A, Korszun R, Hartl FU, Flanagan J. A zinc finger-like domain of the molecular chaperone DnaJ is involved in binding to denatured protein substrates. EMBO J 1996;15:408-17.
18. [18] Engman DM, Sias SR, Gabe JD, Donelson JE, Dragon EA. Comparison of HSP70 genes from two strains of Trypanosoma cruzi. Mol Biochem Parasitol 1989;37:285-7.
19. [19] Olson CL, Nadeau KC, Sullivan MA, Winquist AG, Donelson JE, Walsh CT, Engman DM. Molecular and biochemical comparison of the 70 kDa heat shock proteins of Trypanosoma cruzi. J Biol Chem 1994;269:3868-74.
20. [20] Engman DM, Kirchhoff LV, Donelson JE. Molecular cloning of mtp70, a mitochondrial member of the hsp70 family. Mol Cell Biol 1989;9:5163-8.
21. [21] Engman DM, Fehr SC, Donelson JE. Specific functional domains of mitochondrial hsp70s suggested by sequence comparison of the trypanosome and yeast proteins. Mol Biochem Parasitol 1992;51:153-5.
22. [22] Tibbetts RS, Kim IY, Olson CL, Barthel LM, Sullivan MA, Winquist AG, Miller SD, Engman DM. Molecular cloning and characterization of the 78 kDa glucose regulated protein of Trypanosoma cruzi. Infect Immun 1994;62:2499-507.
23. [23] Kirchhoff LV, Neva FA. Chagas' disease in Latin American immigrants. J Am Med Assoc 1985;254:3058-60.
24. [24] Kirchhoff LV, Hieny S, Shiver GM, Snary D, Sher A. Cryptic epitope explains the failure of a monoclonal antibody to bind to certain isolates of Trypanosoma cruzi. J Immunol 1984;133:2731-5.
25. [25] Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
26. [26] Gross-Bellard M, Oudet P, Chambon P. Isolation of high-molecular-weight DNA from mammalian cells. Eur J Biochem 1973;36:32-8.
27. [27] Walder JA, Eder PS, Engman DM, Brentano ST, Walder RY, Knutzon DS, Dorfman DM, Donelson JE. The 35-nucleotide spliced leader sequence is common to all trypanosome messenger RNAs. Science 1986;233:569-71.
28. [28] Caplan AJ, Tsai J, Casey PJ, Douglas MG. Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae. J Biol Chem 1992;267:18990-5.
29. [29] Zhu JK, Bressan RA, Hasegawa PM. Isoprenylation of the plant molecular chaperone ANJ1 facilitates membrane association and function at high temperature. Proc Natl Acad Sci USA 1993;90:8557-61.
30. [30] Dragon EA, Sias SR, Kato EA, Gabe JD. The genome of Trypanosoma cruzi contains a constitutively expressed, tandemly arranged multicopy gene homologous to a major heat shock protein. Mol Cell Biol 1987;7:1271-5.
31. [31] Sullivan MA, Olson CL, Winquist AG, Engman DM. Expression and localization of Trypanosoma cruzi hsp60. Mol Biochem Parasitol 1994;68:197-208.