Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside

Integrative Cancer Therapies

Volumn 6, Issue 4, 2007, Pages 354-364

  Newman, Robert A ^a   Kondo, Yasuko ^a   Yokoyama, Tomohisa ^a   Dixon, Susan ^a   Cartwright, Carrie ^a   Chan, Diana ^a   Johansen, Mary ^a   Peiying Yang, ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Autophagosome; Autophagy; Cardiac glycoside; Mitochondria; Nerium oleander; Oleandrin; Pancreatic cancer

Indexed keywords

CARDIAC GLYCOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; OLEANDRIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL PROLIFERATION; CELL VACUOLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; DRUG MECHANISM; HUMAN; HUMAN CELL; LYSOSOME; MITOCHONDRION; PANCREAS TUMOR; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL; UPREGULATION;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; BLOTTING, WESTERN; CARDENOLIDES; CARDIAC GLYCOSIDES; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIPIDS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MOLECULAR STRUCTURE; ORGANIC CHEMICALS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SOLUBILITY; TRANSFECTION;

EID: 36249023658     PISSN: 15347354     EISSN: 1552695X     Source Type: Journal    
DOI: 10.1177/1534735407309623     Document Type: Article

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