Dynein participates in chromosome segregation in fission yeast

Biology of the Cell

Volumn 99, Issue 11, 2007, Pages 627-637

  Courtheoux, Thibault ^a   Gay, Guillaume ^a   Reyes, Céline ^a   Goldstone, Sherilyn ^a   Gachet, Yannick ^a   Tournier, Sylvie ^a  

^a Université de Toulouse Paul Sabatier   (France)

Author keywords

Chromosome segregation; Dynein; Fission yeast; Kinetochore; Mad2; Spindle checkpoint

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; DYNEIN ADENOSINE TRIPHOSPHATASE HEAVY CHAIN; DYNEIN ADENOSINE TRIPHOSPHATASE LIGHT CHAIN; PROTEIN MAD2; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CENTROMERE; CHROMOSOME ABERRATION; CHROMOSOME LOSS; CHROMOSOME SEGREGATION; CONTROLLED STUDY; METAPHASE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; YEAST; YEAST CELL;

ANAPHASE; CELL CYCLE PROTEINS; CHROMATIDS; CHROMOSOME SEGREGATION; CHROMOSOMES, FUNGAL; DYNEIN ATPASE; GENE DELETION; KINETOCHORES; METAPHASE; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; NUCLEAR PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

EUKARYOTA; SCHIZOSACCHAROMYCETACEAE;

EID: 36249017213     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1042/BC20070047     Document Type: Article

References (55)

1. Asakawa, K. and Toda, T. (2006) Cooperation of EB1-Mal3 and the Bub1 spindle checkpoint. Cell Cycle 5, 27-30
2. Asakawa, K., Toya, M., Sato, M., Kanal, M., Kume, K., Goshima, T, Garcia, M.A., Hirata, D. and Toda, T (2005) Mal3, the fission yeast EB1 homologue, cooperates with Bub1 spindle checkpoint to prevent monopolar attachment. EMBO Rep. 6, 1194-1200
3. Bernard, R, Hardwick, K. and Javerzat, J.P. (1998) Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploldy through mitosis. J. Cell Biol. 143, 1775-1787
4. Chen, R.H., Brady, D.M., Smith, D., Murray, A.W. and Hardwick, K.G. (1999) The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins. Mol. Biol. Cell 10, 2607-2618
5. Cleveland, D.W., Mao, Y. and Sullivan, K.F. (2003) Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 112, 407-421
6. DeLuca, J.G., Gall, W.E., Ciferri, C., Cimini, D., Musacchio, A. and Salmon, E.D. (2006) Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell 127, 969-982
7. Ding, D.Q., Chikashige, Y, Haraguchi, T. and Hiraoka, Y. (1998) Oscillatory nuclear movement in fission yeast meiotic prophase is driven by astral microtubules, as revealed by continuous observation of chromosomes and microtubules in living cells. J. Cell Sci. 111, 701-712
8. Funabiki, H., Hagan, I., Uzawa, S. and Yanagida, M. (1993) Cell cycle-dependent specific positioning and clustering of centromeres; and telomeres; in fission yeast. J. Cell Biol. 121, 961-976
9. Gachet, Y., Tournier, S., Millar, J.B. and Hyams, J.S. (2004) Mechanism controlling perpendicular alignment of the spindle to the axis of cell division in fission yeast. EMBO J. 23, 1289-1300
10. Gaglio, T, Dionne, M.A. and Compton, D.A. (1997) Mitotic spindle poles are organized by structural and motor proteins in addition to centrosomes. J. Cell Biol. 138, 1055-1066
11. Garcia, M.A., Koonrugsa, N. and Toda, T. (2002) Spindle-kinetochore attachment requires the combined action of Kin I-like Klp5/6 and Alp14/ Dis1-MAPs in fission yeast. EMBO J. 21, 6015-6024
12. Goshima, G. and Vale, R.D. (2003) The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line. J. Cell Biol. 162, 1003-1016
13. Grallert, A., Beuter, C., Craven, R.A., Bagley, S., Wilks, D., Fleig, U. and Hagan, I.M. (2006) S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner. Genes Dev. 20, 2421-2436
14. Grishchuk, E.L. and McIntosh, J.R. (2006) Microtubule depolymerization can drive poleward chromosome motion in fission yeast. EMBO J. 25, 4888-4896
15. Grishchuk, E.L., Spiridonov, I.S. and McIntosh, J.R. (2007) Mitotic chromosome biorientation in fission yeast is enhanced by dynein and a minus-end-directed, kinesin-like protein. Mol. Biol. Cell 18, 2216-2225
16. Hartwell, L.H. and Weinert, T.A. (1989) Checkpoints: controls that ensure the order of cell cycle events. Science 246, 629-634
17. He, X., Patterson, T.E. and Sazer, S. (1997) The Schizoseccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex. Proc. Natl. Acad. Sci. U.S.A. 94, 7965-7970
18. Heald, R., Tournebize, R., Blank, T., Sandaltzopoulos, R., Becker, P., Hyman, A. and Karsenti, E. (1996) Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature 382, 420-425
19. Hoffman, D.B., Pearson, C.G., Yen, T.J., Howell, B.J. and Salmon, E.D. (2001) Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores. Mol. Biol. Cell 12, 1995-2009
20. Howell, B.J., McEwen, B.F, Canman, J.C., Hoffman, D.B., Farrar, E.M., Rieder, C.L. and Salmon, E.D. (2001) Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint Inactivation. J. Cell Biol. 155, 1159-1172
21. Ikui, A.E., Furuya, K., Yanagida, M. and Matsumoto, T. (2002) Control of localization of a spindle checkpoint protein, Mad2, in fission yeast. J. Cell Sci. 115, 1603-1610
22. Javerzat, J.P., Cranston, G. and Allshire, R.C. (1996) Fission yeast genes which disrupt mitotic chromosome segregation when overexpressed. Nucleic Acids Res. 24, 4676-4683
23. King, J.M. and Nicklas, R.B. (2000) Tension on chromosomes increases the number of kinetochore microtubules but only within limits. J. Cell Sci. 113, 3815-3823
24. Li, X. and Nickles, R.B. (1995) Mitotic forces control a cell-cycle checkpoint. Nature 373, 630-632
25. Li, Y. and Benezra, R. (1996) Identification of a human mitotic checkpoint gene: hsMAD2. Science 274, 246-248
26. Maiato, H., DeLuca, J., Salmon, E.D. and Eamshaw, W.C. (2004) The dynamic kinetochore-microtubule interface. J. Cell Sci. 117, 5461-5477
27. Mao, Y, Desai, A. and Cleveland, D.W. (2005) Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. J. Cell Biol. 170, 873-880
28. McIntosh, J.R. and Hering, G.E. (1991) Spindle fiber action and chromosome movement. Annu. Rev. Cell Biol. 7, 403-426
29. Merdes, A. and De Mey, J. (1990) The mechanism of kinetochore-spindle attachment and polowards movement analyzed in PtK2 cells at the prophase-prometaphase transition. Eur. J. Cell Biol. 53, 313-325
30. Merdes, A., Heald, R., Samejima, K., Eamshaw, W.C. and Cleveland, D.W. (2000) Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. J. Cell Biol. 149, 851-862
31. Miki, F., Okazaki, K., Shimanuki, M., Yamamoto, A., Hiraoka, Y. and Niwa, O. (2002) The 14-kDa dynein light chain-family protein Dlc1 is required for regular oscillatory nuclear movement and efficient recombination during meiotic prophase in fission yeast. Mol. Biol. Cell 13, 930-946
32. Millband, D.N. and Hardwick, K.G. (2002) Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores; in a Bub1p-, Bub3p-, and Mph1p-dependent manner. Mol. Cell Biol. 22, 2728-2742
33. Moreno, S., Klar, A. and Nurse, P. (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194, 795-823
34. Mulvihill, D.P., Barretto, C. and Hyams, J.S. (2001) Localization of fission yeast typell myosin, Myo2, to the cytokinetic actin ring is regulated by phosphorylation of a C-terminal coiled-coil domain and requires a functional septation initiation network. Mol. Biol. Cell 12, 4044-4053
35. Nabeshima, K., Nakagawa, T, Straight, A.F., Murray, A., Chikashige, Y., Yamashita, Y.M., Hiraoka, Y. and Yanagida, M. (1998) Dynamics of centromeres during metaphase-anaphase transition in fission yeast: Dis1 is implicated in force balance in metaphase bipolar spindle. Mol. Biol. Cell 9, 3211-3225
36. Rieder, C.L. and Alexander, S.P. (1990) Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells. J. Cell Biol. 110, 81-95
37. Rieder, C.L., Schultz, A., Cole, R. and Sluder, G. (1994) Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle. J. Cell Biol. 127, 1301-1310
38. Rieder, C.L., Cole, R.W., Khodjakov, A. and Sluder, G. (1995) The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores. J. Cell Biol. 130, 941-948
39. Savoian, M.S., Goldberg, M.L. and Rieder, C.L. (2000) The rate of poleward chromosome motion is attenuated in Drosophila zw10 and rod mutants. Nat. Cell Biol. 2, 948-952
40. Shannon, K.B., Canman, J.C. and Salmon, E.D. (2002) Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension. Mol. Blol. Cell 13, 3706-3719
41. Sharp, D.J., Rogers, G.C. and Scholey, J.M. (2000) Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos. Nat. Cell Biol. 2, 922-930
42. Skoufias, D.A., Andreassen, P.R., Lacroix, F.B., Wilson, L. and Margolis, R.L. (2001) Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints. Proc. Natl. Acad. Sci. U.S.A. 98, 4492-4497
43. Stern, B.M. and Murray, A.W. (2001) Lack of tension at kinetochores activates the spindle checkpoint in budding yeast. Curr. Biol. 11, 1462-1467
44. Tanaka, K., Mukae, N., Dewar, H., van Breugel, M., James, E.K., Prescott, A.R., Antony, C. and Tanaka, T.U. (2005) Molecular mechanisms of kinetochore capture by spindle microtubules. Nature 434, 987-994
45. Tatebe, H., Goshima, G., Takeda, K., Nakagawa, T, Kinoshita, K. and Yanagida, M. (2001) Fission yeast living mitosis visualized by GFP-tagged gene products. Micron 32, 67-74
46. Tournier, S., Gachet, Y., Buck, V., Hyams, J.S. and Millar, J.B. (2004) Disruption of astral microtubule contact with the cell cortex activates a Bub1, Bub3, and Mad3-dependent checkpoint in fission yeast. Mol. Biol. Cell 15, 3345-3356
47. +: two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis. Mol. Biol. Cell 12, 3476-3488
48. Vale, R.D. (2003) The molecular motor toolbox for intracellular transport. Cell 112, 467-480
49. Walczak, C.E., Vernos, I., Mitchison, T.J., Karsenti, E. and Heald, R. (1998) A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity. Curr. Biol. 8, 903-913
50. Waters, J.C., Chen, R.H., Murray, A.W. and Salmon, E.D. (1998) Localization of Mad2 to kinetochores depends on microtubule attachment, not tension. J. Cell Biol. 141, 1181-1191
51. Weiss, E. and Winey, M. (1996) The Saccharomyces cerevisiae spindle pole body duplication gone MPS1 is part of a mitotic checkpoint. J. Cell Biol. 132, 111-123
52. Wu, J.Q., Kuhn, J.R., Kovar, D.R. and Pollard, T.D. (2003) Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis. Dev. Cell 5, 723-734
53. Yamamoto, A., West, R.R., McIntosh, J.R. and Hiraoka, Y. (1999) A cytoplasmic dynein heavy chain is required for oscillatory nuclear movement of meiotic prophase and efficient meiotic recombination in fission yeast. J. Cell Biol. 145, 1233-1249
54. Yu, H. (2002) Regulation of APC-Cdc20 by the spindle checkpoint. Curr. Opin. Cell Biol. 14, 706-714
55. Zhou, J., Yao, J. and Joshi, H.C. (2002) Attachment and tension in the spindle assembly checkpoint. J. Cell Sci. 115, 3547-3555