Synthesis of unsymmetrical and regio-defined 2,3,6-quinoxaline and 2,3,7-pyridopyrazine derivatives

Tetrahedron Letters

Volumn 48, Issue 51, 2007, Pages 8943-8946

  Sherman, Dan ^a   Kawakami, Joel ^a   He, Hai Ying ^a   Dhun, Farah ^a   Rios, Raphael ^a   Liu, Hu ^a   Pan, Weitao ^a   Xu, Yong Jiang ^a   Hong, Sang phyo ^a   Arbour, Melissa ^a   Labelle, Marc ^a   Duncton, Matthew A J ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,6 QUINOXALINE DERIVATIVE; 2,3,7 PYRIDOPYRAZINE DERIVATIVE; PYRAZINE DERIVATIVE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUZUKI REACTION; SYNTHESIS;

EID: 36248989120     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.10.117     Document Type: Article

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31. 2, or ligand, was not performed. However, previous efforts to directly displace the chloro-group from compound 15 using either an alcohol or an alkoxide were unsuccessful.