메뉴 건너뛰기




Volumn 33, Issue 8, 2007, Pages 757-761

Oxygen carriers and cancer chemo- and radiotherapy sensitization: Bench to bedside and back

Author keywords

Cancer therapy; Drug resistance; Hypoxia; Oxygen carriers; Radiation sensitizing agents

Indexed keywords

BLEOMYCIN; BLOOD SUBSTITUTE; CARBOGEN; CARBOPLATIN; CARMUSTINE; CATALASE; CHLOROZOTOCIN; CISPLATIN; CROSS LINKED HEMOGLOBIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOSOL; FLUOSOL DA; HEMOGLOBIN; IFOSFAMIDE; LOMUSTINE; MACROGOL; MELPHALAN; MONOPHENOL MONOOXYGENASE; NITROSOUREA; OXYGEN; PERFLUORO COMPOUND; PERFLUOROOCTYL BROMIDE; PERFLUOROPENTANE; PLASMA SUBSTITUTE; POLYMERIZED HEMOGLOBIN; PORPHYRIN; SUPEROXIDE DISMUTASE; THIOTEPA; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 36148991843     PISSN: 03057372     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ctrv.2007.08.002     Document Type: Review
Times cited : (38)

References (63)
  • 1
    • 34547098129 scopus 로고    scopus 로고
    • Targeting hypoxia cell signaling for cancer therapy
    • Melillo G. Targeting hypoxia cell signaling for cancer therapy. Cancer Metastasis Rev 26 (2007) 341-352
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 341-352
    • Melillo, G.1
  • 2
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown J.M., and Wilson W.R. Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 4 (2004) 437-447
    • (2004) Nat Rev Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 3
    • 0030069889 scopus 로고    scopus 로고
    • Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers
    • Overgaard J., and Horsman M.R. Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol 6 (1996) 10-21
    • (1996) Semin Radiat Oncol , vol.6 , pp. 10-21
    • Overgaard, J.1    Horsman, M.R.2
  • 4
    • 0036898268 scopus 로고    scopus 로고
    • ARCON: a novel biology-based approach in radiotherapy
    • Kaanders J.H., Bussink J., and van der Kogel A.J. ARCON: a novel biology-based approach in radiotherapy. Lancet Oncol 3 (2002) 728-737
    • (2002) Lancet Oncol , vol.3 , pp. 728-737
    • Kaanders, J.H.1    Bussink, J.2    van der Kogel, A.J.3
  • 5
    • 29244472455 scopus 로고    scopus 로고
    • Oxygen-modifying treatment with ARCON reduces the prognostic significance of hemoglobin in squamous cell carcinoma of the head and neck
    • Hoogsteen I.J., Pop L.A., Marres H.A., et al. Oxygen-modifying treatment with ARCON reduces the prognostic significance of hemoglobin in squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 64 (2006) 83-89
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 83-89
    • Hoogsteen, I.J.1    Pop, L.A.2    Marres, H.A.3
  • 6
    • 33845888257 scopus 로고    scopus 로고
    • Red cell substitutes
    • Winslow R.M. Red cell substitutes. Semin Hematol 44 (2007) 51-59
    • (2007) Semin Hematol , vol.44 , pp. 51-59
    • Winslow, R.M.1
  • 7
    • 0035465476 scopus 로고    scopus 로고
    • Oxygen carriers ("blood substitutes") - raison d'etre, chemistry, and some physiology
    • Riess J.G. Oxygen carriers ("blood substitutes") - raison d'etre, chemistry, and some physiology. Chem Rev 101 (2001) 2797-2920
    • (2001) Chem Rev , vol.101 , pp. 2797-2920
    • Riess, J.G.1
  • 8
    • 0023697247 scopus 로고
    • Preclinical studies of a perfluorochemical emulsion as an adjunct to radiotherapy
    • Rockwell S., Irvin C.G., and Kelley M. Preclinical studies of a perfluorochemical emulsion as an adjunct to radiotherapy. Int J Radiat Oncol Biol Phys 15 (1988) 913-920
    • (1988) Int J Radiat Oncol Biol Phys , vol.15 , pp. 913-920
    • Rockwell, S.1    Irvin, C.G.2    Kelley, M.3
  • 9
    • 0023796743 scopus 로고
    • Intermittent use of a perfluorochemical emulsion (Fluosol-DA 20%) and carbogen breathing with fractionated irradiation
    • Moulder J.E., and Fish B.L. Intermittent use of a perfluorochemical emulsion (Fluosol-DA 20%) and carbogen breathing with fractionated irradiation. Int J Radiat Oncol Biol Phys 15 (1988) 1193-1196
    • (1988) Int J Radiat Oncol Biol Phys , vol.15 , pp. 1193-1196
    • Moulder, J.E.1    Fish, B.L.2
  • 10
    • 0021324649 scopus 로고
    • Perfluorochemical emulsions can increase tumor radiosensitivity
    • Teicher B.A., and Rose C.M. Perfluorochemical emulsions can increase tumor radiosensitivity. Science 223 (1984) 934-936
    • (1984) Science , vol.223 , pp. 934-936
    • Teicher, B.A.1    Rose, C.M.2
  • 11
    • 0021192849 scopus 로고
    • Oxygen-carrying perfluorochemical emulsion as an adjuvant to radiation therapy in mice
    • Teicher B.A., and Rose C.M. Oxygen-carrying perfluorochemical emulsion as an adjuvant to radiation therapy in mice. Cancer Res 44 (1984) 4285-4288
    • (1984) Cancer Res , vol.44 , pp. 4285-4288
    • Teicher, B.A.1    Rose, C.M.2
  • 12
    • 0022457633 scopus 로고
    • Reactions of tumors and normal tissues in mice to irradiation in the presence and absence of a perfluorochemical emulsion
    • Rockwell S., Mate T.P., Irvin C.G., and Nierenburg M. Reactions of tumors and normal tissues in mice to irradiation in the presence and absence of a perfluorochemical emulsion. Int J Radiat Oncol Biol Phys 12 (1986) 1315-1318
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1315-1318
    • Rockwell, S.1    Mate, T.P.2    Irvin, C.G.3    Nierenburg, M.4
  • 13
    • 0021926012 scopus 로고
    • Use of a perfluorochemical emulsion to improve oxygenation in a solid tumor
    • Rockwell S. Use of a perfluorochemical emulsion to improve oxygenation in a solid tumor. Int J Radiat Oncol Biol Phys 11 (1985) 97-103
    • (1985) Int J Radiat Oncol Biol Phys , vol.11 , pp. 97-103
    • Rockwell, S.1
  • 14
    • 0025685158 scopus 로고
    • Effects of a perfluorochemical emulsion on the response of BA1112 rat rhabdomyosarcomas to continuous low-dose-rate irradiation
    • Morton J.D., Porter E., Yabuki H., Nath R., and Rockwell S. Effects of a perfluorochemical emulsion on the response of BA1112 rat rhabdomyosarcomas to continuous low-dose-rate irradiation. Radiat Res 124 (1990) 178-182
    • (1990) Radiat Res , vol.124 , pp. 178-182
    • Morton, J.D.1    Porter, E.2    Yabuki, H.3    Nath, R.4    Rockwell, S.5
  • 15
    • 0023185229 scopus 로고
    • Enhancement of tumor radiation response by the combination of a perfluorochemical emulsion and hyperbaric oxygen
    • Martin D.F., Porter E.A., Rockwell S., and Fischer J.J. Enhancement of tumor radiation response by the combination of a perfluorochemical emulsion and hyperbaric oxygen. Int J Radiat Oncol Biol Phys 13 (1987) 747-751
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 747-751
    • Martin, D.F.1    Porter, E.A.2    Rockwell, S.3    Fischer, J.J.4
  • 16
    • 0023634812 scopus 로고
    • Effect of a perfluorochemical emulsion on the radiation response of BA1112 rhabdomyosarcomas
    • Martin D.F., Porter E.A., Fischer J.J., and Rockwell S. Effect of a perfluorochemical emulsion on the radiation response of BA1112 rhabdomyosarcomas. Radiat Res 112 (1987) 45-53
    • (1987) Radiat Res , vol.112 , pp. 45-53
    • Martin, D.F.1    Porter, E.A.2    Fischer, J.J.3    Rockwell, S.4
  • 19
    • 0027240060 scopus 로고
    • Lack of complications in long-term survivors after treatment with Fluosol and oxygen as an adjuvant to radiation therapy for high-grade brain tumors
    • Evans R.G., Kimler B.F., Morantz R.A., and Batnitzky S. Lack of complications in long-term survivors after treatment with Fluosol and oxygen as an adjuvant to radiation therapy for high-grade brain tumors. Int J Radiat Oncol Biol Phys 26 (1993) 649-652
    • (1993) Int J Radiat Oncol Biol Phys , vol.26 , pp. 649-652
    • Evans, R.G.1    Kimler, B.F.2    Morantz, R.A.3    Batnitzky, S.4
  • 20
    • 0024380933 scopus 로고
    • Phase I/II study of Fluosol-DA and 100% oxygen as an adjuvant to radiation in the treatment of advanced squamous cell tumors of the head and neck
    • Lustig R., McIntosh-Lowe N., Rose C., et al. Phase I/II study of Fluosol-DA and 100% oxygen as an adjuvant to radiation in the treatment of advanced squamous cell tumors of the head and neck. Int J Radiat Oncol Biol Phys 16 (1989) 1587-1593
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1587-1593
    • Lustig, R.1    McIntosh-Lowe, N.2    Rose, C.3
  • 21
    • 0025194034 scopus 로고
    • Fluosol and oxygen breathing as an adjuvant to radiation therapy in the treatment of locally advanced non-small cell carcinoma of the lung: results of a phase I/II study
    • Lustig R., Lowe N., Prosnitz L., et al. Fluosol and oxygen breathing as an adjuvant to radiation therapy in the treatment of locally advanced non-small cell carcinoma of the lung: results of a phase I/II study. Int J Radiat Oncol Biol Phys 19 (1990) 97-102
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 97-102
    • Lustig, R.1    Lowe, N.2    Prosnitz, L.3
  • 22
    • 0025182414 scopus 로고
    • A phase I/II study of the use of Fluosol as an adjuvant to radiation therapy in the treatment of primary high-grade brain tumors
    • Evans R.G., Kimler B.F., Morantz R.A., et al. A phase I/II study of the use of Fluosol as an adjuvant to radiation therapy in the treatment of primary high-grade brain tumors. Int J Radiat Oncol Biol Phys 19 (1990) 415-420
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 415-420
    • Evans, R.G.1    Kimler, B.F.2    Morantz, R.A.3
  • 23
    • 0026665129 scopus 로고
    • Fluosol and hyperbaric oxygen as an adjunct to radiation therapy in the treatment of malignant gliomas: a pilot study
    • Dowling S., Fischer J.J., and Rockwell S. Fluosol and hyperbaric oxygen as an adjunct to radiation therapy in the treatment of malignant gliomas: a pilot study. Biomater Artif Cells Immobil Biotechnol 20 (1992) 903-905
    • (1992) Biomater Artif Cells Immobil Biotechnol , vol.20 , pp. 903-905
    • Dowling, S.1    Fischer, J.J.2    Rockwell, S.3
  • 24
    • 0024349643 scopus 로고
    • Optimization of perfluorochemical levels with radiation therapy in mice
    • Teicher B.A., Herman T.S., and Jones S.M. Optimization of perfluorochemical levels with radiation therapy in mice. Cancer Res 49 (1989) 2693-2697
    • (1989) Cancer Res , vol.49 , pp. 2693-2697
    • Teicher, B.A.1    Herman, T.S.2    Jones, S.M.3
  • 25
    • 0025162889 scopus 로고
    • Influence of scheduling, dose, and volume of administration of a perfluorochemical emulsion on tumor response to radiation therapy
    • Teicher B.A., Herman T.S., and Jones S.M. Influence of scheduling, dose, and volume of administration of a perfluorochemical emulsion on tumor response to radiation therapy. Int J Radiat Oncol Biol Phys 19 (1990) 945-951
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 945-951
    • Teicher, B.A.1    Herman, T.S.2    Jones, S.M.3
  • 26
    • 0026091775 scopus 로고
    • Effect of oxygen level on the enhancement of tumor response to radiation by perfluorochemical emulsions or a bovine hemoglobin preparation
    • Teicher B.A., Herman T.S., Hopkins R.E., and Menon K. Effect of oxygen level on the enhancement of tumor response to radiation by perfluorochemical emulsions or a bovine hemoglobin preparation. Int J Radiat Oncol Biol Phys 21 (1991) 969-974
    • (1991) Int J Radiat Oncol Biol Phys , vol.21 , pp. 969-974
    • Teicher, B.A.1    Herman, T.S.2    Hopkins, R.E.3    Menon, K.4
  • 27
    • 0026641450 scopus 로고
    • Response of subpopulations of the FSall C fibrosarcoma to low dose X-rays and various potential enhancing agents
    • Tanaka J., Holden S.A., Herman T.S., and Teicher B.A. Response of subpopulations of the FSall C fibrosarcoma to low dose X-rays and various potential enhancing agents. Anticancer Res 12 (1992) 1029-1033
    • (1992) Anticancer Res , vol.12 , pp. 1029-1033
    • Tanaka, J.1    Holden, S.A.2    Herman, T.S.3    Teicher, B.A.4
  • 28
    • 0024474683 scopus 로고
    • New high O2 carrying perfluorochemical emulsions and/or carbogen: reactions of a human tumor xenograft to irradiation
    • Thomas C., Lartigau E., Malaise E.P., and Guichard M. New high O2 carrying perfluorochemical emulsions and/or carbogen: reactions of a human tumor xenograft to irradiation. Int J Radiat Oncol Biol Phys 16 (1989) 1157-1160
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1157-1160
    • Thomas, C.1    Lartigau, E.2    Malaise, E.P.3    Guichard, M.4
  • 30
    • 0026671081 scopus 로고
    • Enhancement of fractionated radiation therapy by an experimental concentrated perflubron emulsion (Oxygent) in the Lewis lung carcinoma
    • Teicher B.A., Herman T.S., and Menon K. Enhancement of fractionated radiation therapy by an experimental concentrated perflubron emulsion (Oxygent) in the Lewis lung carcinoma. Biomater Artif Cells Immobil Biotechnol 20 (1992) 899-902
    • (1992) Biomater Artif Cells Immobil Biotechnol , vol.20 , pp. 899-902
    • Teicher, B.A.1    Herman, T.S.2    Menon, K.3
  • 31
    • 0027930494 scopus 로고
    • Tumor oxygenation after (1) carbogen and/or perflubron emulsion administration in tumor xenografts (2) carbogen administration in patients
    • Guichard M., Lartigau E., Martin L., et al. Tumor oxygenation after (1) carbogen and/or perflubron emulsion administration in tumor xenografts (2) carbogen administration in patients. Artif Cells Blood Substit Immobil Biotechnol 22 (1994) 1355-1360
    • (1994) Artif Cells Blood Substit Immobil Biotechnol , vol.22 , pp. 1355-1360
    • Guichard, M.1    Lartigau, E.2    Martin, L.3
  • 32
    • 0028048012 scopus 로고
    • Combination of perfluorochemical emulsions and carbogen breathing with cancer chemotherapy
    • Teicher B.A. Combination of perfluorochemical emulsions and carbogen breathing with cancer chemotherapy. Artif Cells Blood Substit Immobil Biotechnol 22 (1994) 1109-1120
    • (1994) Artif Cells Blood Substit Immobil Biotechnol , vol.22 , pp. 1109-1120
    • Teicher, B.A.1
  • 33
    • 0030294383 scopus 로고    scopus 로고
    • Efficacy of agents counteracting hypoxia in fractionated radiation regimes
    • Stern S., and Guichard M. Efficacy of agents counteracting hypoxia in fractionated radiation regimes. Radiother Oncol 41 (1996) 143-149
    • (1996) Radiother Oncol , vol.41 , pp. 143-149
    • Stern, S.1    Guichard, M.2
  • 34
    • 0036645420 scopus 로고    scopus 로고
    • Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion
    • Koch C.J., Oprysko P.R., Shuman A.L., Jenkins W.T., Brandt G., and Evans S.M. Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion. Cancer Res 62 (2002) 3626-3629
    • (2002) Cancer Res , vol.62 , pp. 3626-3629
    • Koch, C.J.1    Oprysko, P.R.2    Shuman, A.L.3    Jenkins, W.T.4    Brandt, G.5    Evans, S.M.6
  • 35
    • 0023925469 scopus 로고
    • Modification of photodynamic therapy-induced hypoxia by FLuosol-DA (20%) and carbogen breathing in mice
    • Fingar V.H., Mang T.S., and Henderson B.W. Modification of photodynamic therapy-induced hypoxia by FLuosol-DA (20%) and carbogen breathing in mice. Cancer Res 48 (1988) 3350-3354
    • (1988) Cancer Res , vol.48 , pp. 3350-3354
    • Fingar, V.H.1    Mang, T.S.2    Henderson, B.W.3
  • 36
    • 0025411922 scopus 로고
    • Influence of fluorocarbon emulsions on porphyrin-sensitised oxidation of histidine
    • Chowdhary R.K., Cundall R.B., and Morgan C.G. Influence of fluorocarbon emulsions on porphyrin-sensitised oxidation of histidine. Photochem Photobiol 51 (1990) 395-399
    • (1990) Photochem Photobiol , vol.51 , pp. 395-399
    • Chowdhary, R.K.1    Cundall, R.B.2    Morgan, C.G.3
  • 37
    • 33645222038 scopus 로고    scopus 로고
    • Enhancing the photodynamic effect of hypericin in human bladder transitional cell carcinoma spheroids by the use of the oxygen carrier, perfluorodecalin
    • Kamuhabwa A.R., Huygens A., Roskams T., and De Witte P.A. Enhancing the photodynamic effect of hypericin in human bladder transitional cell carcinoma spheroids by the use of the oxygen carrier, perfluorodecalin. Int J Oncol 28 (2006) 775-780
    • (2006) Int J Oncol , vol.28 , pp. 775-780
    • Kamuhabwa, A.R.1    Huygens, A.2    Roskams, T.3    De Witte, P.A.4
  • 41
    • 0023757153 scopus 로고
    • Effect of Fluosol-DA on the response of intracranial 9L tumors to X rays and BCNU
    • Teicher B.A., Herman T.S., and Rose C.M. Effect of Fluosol-DA on the response of intracranial 9L tumors to X rays and BCNU. Int J Radiat Oncol Biol Phys 15 (1988) 1187-1192
    • (1988) Int J Radiat Oncol Biol Phys , vol.15 , pp. 1187-1192
    • Teicher, B.A.1    Herman, T.S.2    Rose, C.M.3
  • 42
    • 0022497349 scopus 로고
    • 2 on tumor-cell and bone-marrow cytotoxicity of nitrosoureas in mice bearing FSA-II fibrosarcoma
    • 2 on tumor-cell and bone-marrow cytotoxicity of nitrosoureas in mice bearing FSA-II fibrosarcoma. Int J Cancer 38 (1986) 285-288
    • (1986) Int J Cancer , vol.38 , pp. 285-288
    • Teicher, B.A.1    Holden, S.A.2    Rose, C.M.3
  • 43
    • 0023775083 scopus 로고
    • Effect of various oxygenation conditions and fluosol-DA on cancer chemotherapeutic agents
    • Teicher B.A., McIntosh-Lowe N.L., and Rose C.M. Effect of various oxygenation conditions and fluosol-DA on cancer chemotherapeutic agents. Biomater Artif Cells Artif Organs 16 (1988) 533-546
    • (1988) Biomater Artif Cells Artif Organs , vol.16 , pp. 533-546
    • Teicher, B.A.1    McIntosh-Lowe, N.L.2    Rose, C.M.3
  • 44
    • 0024351631 scopus 로고
    • The influence of Fluosol-DA and carbogen breathing on the antitumor effects of cyclophosphamide in vivo
    • Kim G.E., and Song C.W. The influence of Fluosol-DA and carbogen breathing on the antitumor effects of cyclophosphamide in vivo. Cancer Chemother Pharmacol 25 (1989) 99-102
    • (1989) Cancer Chemother Pharmacol , vol.25 , pp. 99-102
    • Kim, G.E.1    Song, C.W.2
  • 45
    • 0023092376 scopus 로고
    • Approaches to defining the mechanism of enhancement by Fluosol-DA 20% with carbogen of melphalan antitumor activity
    • Teicher B.A., Holden S.A., and Jacobs J.L. Approaches to defining the mechanism of enhancement by Fluosol-DA 20% with carbogen of melphalan antitumor activity. Cancer Res 47 (1987) 513-518
    • (1987) Cancer Res , vol.47 , pp. 513-518
    • Teicher, B.A.1    Holden, S.A.2    Jacobs, J.L.3
  • 46
    • 0024459584 scopus 로고
    • Evidence for enzymatic activation and oxygen involvement in cytotoxicity and antitumor activity of N,N′,N″- triethylenethiophosphoramide
    • Teicher B.A., Waxman D.J., Holden S.A., et al. Evidence for enzymatic activation and oxygen involvement in cytotoxicity and antitumor activity of N,N′,N″- triethylenethiophosphoramide. Cancer Res 49 (1989) 4996-5001
    • (1989) Cancer Res , vol.49 , pp. 4996-5001
    • Teicher, B.A.1    Waxman, D.J.2    Holden, S.A.3
  • 47
    • 0026616256 scopus 로고
    • Enhancement by perflusion emulsion (Oxygent) and carbogen breathing of the tumor growth delay of the FSaIIC fibrosarcoma after treatment with antitumor alkylating agents
    • Holden S.A., Teicher B.A., Ha C., Ara G., and Herman T.S. Enhancement by perflusion emulsion (Oxygent) and carbogen breathing of the tumor growth delay of the FSaIIC fibrosarcoma after treatment with antitumor alkylating agents. Biomater Artif Cells Immobil Biotechnol 20 (1992) 895-898
    • (1992) Biomater Artif Cells Immobil Biotechnol , vol.20 , pp. 895-898
    • Holden, S.A.1    Teicher, B.A.2    Ha, C.3    Ara, G.4    Herman, T.S.5
  • 48
    • 0026663911 scopus 로고
    • A new concentrated perfluorochemical emulsion and carbogen breathing as an adjuvant to treatment with antitumor alkylating agents
    • Teicher B.A., Holden S.A., Ara G., Ha C.S., Herman T.S., and Northey D. A new concentrated perfluorochemical emulsion and carbogen breathing as an adjuvant to treatment with antitumor alkylating agents. J Cancer Res Clin Oncol 118 (1992) 509-514
    • (1992) J Cancer Res Clin Oncol , vol.118 , pp. 509-514
    • Teicher, B.A.1    Holden, S.A.2    Ara, G.3    Ha, C.S.4    Herman, T.S.5    Northey, D.6
  • 49
    • 0028070110 scopus 로고
    • Oxygenation of the rat 9L gliosarcoma and the rat 13672 mammary carcinoma with various doses of a hemoglobin solution
    • Teicher B.A., Holden S.A., Dupuis N.P., et al. Oxygenation of the rat 9L gliosarcoma and the rat 13672 mammary carcinoma with various doses of a hemoglobin solution. Artif Cells Blood Substit Immobil Biotechnol 22 (1994) 827-833
    • (1994) Artif Cells Blood Substit Immobil Biotechnol , vol.22 , pp. 827-833
    • Teicher, B.A.1    Holden, S.A.2    Dupuis, N.P.3
  • 52
    • 0026673272 scopus 로고
    • Effect of a bovine hemoglobin preparation (SBHS) on the response of two murine solid tumors to radiation therapy or chemotherapeutic alkylating agents
    • Teicher B.A., Holden S.A., Ara G., Herman T.S., Hopkins R.E., and Menon K. Effect of a bovine hemoglobin preparation (SBHS) on the response of two murine solid tumors to radiation therapy or chemotherapeutic alkylating agents. Biomater Artif Cells Immobil Biotechnol 20 (1992) 657-660
    • (1992) Biomater Artif Cells Immobil Biotechnol , vol.20 , pp. 657-660
    • Teicher, B.A.1    Holden, S.A.2    Ara, G.3    Herman, T.S.4    Hopkins, R.E.5    Menon, K.6
  • 53
    • 0028923874 scopus 로고
    • Increased efficacy of chemo- and radio-therapy by a hemoglobin solution in the 9L gliosarcoma
    • Teicher B.A., Dupuis N.P., Emi Y., Ikebe M., Kakeji Y., and Menon K. Increased efficacy of chemo- and radio-therapy by a hemoglobin solution in the 9L gliosarcoma. In Vivo 9 (1995) 11-18
    • (1995) In Vivo , vol.9 , pp. 11-18
    • Teicher, B.A.1    Dupuis, N.P.2    Emi, Y.3    Ikebe, M.4    Kakeji, Y.5    Menon, K.6
  • 54
    • 0027421073 scopus 로고
    • Effect of hemoglobin solution on the response of intracranial and subcutaneous 9L tumors to antitumor alkylating agents
    • Teicher B.A., Holden S.A., Menon K., Hopkins R.E., and Gawryl M.S. Effect of hemoglobin solution on the response of intracranial and subcutaneous 9L tumors to antitumor alkylating agents. Cancer Chemother Pharmacol 33 (1993) 57-62
    • (1993) Cancer Chemother Pharmacol , vol.33 , pp. 57-62
    • Teicher, B.A.1    Holden, S.A.2    Menon, K.3    Hopkins, R.E.4    Gawryl, M.S.5
  • 55
    • 0031806430 scopus 로고    scopus 로고
    • Increased tissue oxygenation and enhanced radiation sensitivity of solid tumors in rodents following polyethylene glycol conjugated bovine hemoglobin administration
    • Linberg R., Conover C.D., Shum K.L., and Shorr R.G. Increased tissue oxygenation and enhanced radiation sensitivity of solid tumors in rodents following polyethylene glycol conjugated bovine hemoglobin administration. In Vivo 12 (1998) 167-173
    • (1998) In Vivo , vol.12 , pp. 167-173
    • Linberg, R.1    Conover, C.D.2    Shum, K.L.3    Shorr, R.G.4
  • 57
    • 0032966010 scopus 로고    scopus 로고
    • Changes in the functional properties of bovine hemoglobin induced by covalent modification with polyethylene glycol
    • Shorr R.G., Kwong S., Gilbert C., and Benesch R.E. Changes in the functional properties of bovine hemoglobin induced by covalent modification with polyethylene glycol. Artif Cells Blood Substit Immobil Biotechnol 27 (1999) 185-202
    • (1999) Artif Cells Blood Substit Immobil Biotechnol , vol.27 , pp. 185-202
    • Shorr, R.G.1    Kwong, S.2    Gilbert, C.3    Benesch, R.E.4
  • 58
    • 27544483180 scopus 로고    scopus 로고
    • No effect of the hemoglobin solution HBOC-201 on the response of the rat R1H tumor to fractionated irradiation
    • Raabe A., Gottschalk A., Hommel M., Dubben H.H., and Strandl T. No effect of the hemoglobin solution HBOC-201 on the response of the rat R1H tumor to fractionated irradiation. Strahlenther Onkol 181 (2005) 730-737
    • (2005) Strahlenther Onkol , vol.181 , pp. 730-737
    • Raabe, A.1    Gottschalk, A.2    Hommel, M.3    Dubben, H.H.4    Strandl, T.5
  • 60
    • 0029766826 scopus 로고    scopus 로고
    • Bovine haemoglobin is more potent than autologous red blood cells in restoring muscular tissue oxygenation after profound isovolaemic haemodilution in dogs
    • Standl T., Horn P., Wilhelm S., et al. Bovine haemoglobin is more potent than autologous red blood cells in restoring muscular tissue oxygenation after profound isovolaemic haemodilution in dogs. Can J Anaesth 43 (1996) 714-723
    • (1996) Can J Anaesth , vol.43 , pp. 714-723
    • Standl, T.1    Horn, P.2    Wilhelm, S.3
  • 61
    • 33745926240 scopus 로고    scopus 로고
    • Blood substitutes based on nanobiotechnology
    • Chang T.M. Blood substitutes based on nanobiotechnology. Trends Biotechnol 24 (2006) 372-377
    • (2006) Trends Biotechnol , vol.24 , pp. 372-377
    • Chang, T.M.1
  • 63
    • 33748417743 scopus 로고    scopus 로고
    • A polymerized bovine hemoglobin oxygen carrier preserves regional myocardial function and reduces infarct size after acute myocardial ischemia
    • George I., Yi G.H., Schulman A.R., et al. A polymerized bovine hemoglobin oxygen carrier preserves regional myocardial function and reduces infarct size after acute myocardial ischemia. Am J Physiol Heart Circ Physiol 291 (2006) H1126-H1137
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • George, I.1    Yi, G.H.2    Schulman, A.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.