-
1
-
-
0028559753
-
The effect of the perflubron emulsion Oxygent™ on the calibration characteristics of polaragraphic oxygen electrodes
-
[1] Brizel, D.M., Dodge, R. and Dewhirst, M.W. The effect of the perflubron emulsion Oxygent™ on the calibration characteristics of polaragraphic oxygen electrodes. Radiother. Oncol. 33: 262-265, 1994.
-
(1994)
Radiother. Oncol.
, vol.33
, pp. 262-265
-
-
Brizel, D.M.1
Dodge, R.2
Dewhirst, M.W.3
-
2
-
-
0025646401
-
Potentiation by the hypoxic cytotoxin SR4233 of cell killing produced by fractionated irradiation of mouse tumors
-
[2] Brown, J.M. and Lemmon, M.J. Potentiation by the hypoxic cytotoxin SR4233 of cell killing produced by fractionated irradiation of mouse tumors. Cancer Res. 50: 7745-7749, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 7745-7749
-
-
Brown, J.M.1
Lemmon, M.J.2
-
3
-
-
0025968030
-
SR 4233: A tumor specific radiosensitizer active in fractionated radiation regimes
-
[3] Brown, J.M. and Lemmon, M.J. SR 4233: a tumor specific radiosensitizer active in fractionated radiation regimes. Radiother. Oncol. Suppl. 20: 151-156, 1991.
-
(1991)
Radiother. Oncol. Suppl.
, vol.20
, pp. 151-156
-
-
Brown, J.M.1
Lemmon, M.J.2
-
4
-
-
0025972731
-
Tumor hypoxia can be exploited to preferentially sensitize tumors to fractionated irradiation
-
[4] Brown, J.M. and Lemmon, M.J. Tumor hypoxia can be exploited to preferentially sensitize tumors to fractionated irradiation. Int. J. Radiat. Oncol. Biol. Phys. 20: 457-461, 1991.
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.20
, pp. 457-461
-
-
Brown, J.M.1
Lemmon, M.J.2
-
5
-
-
0011276770
-
Fractionation increases the anti-tumor effect of adding a hypoxic cytotoxin to irradiation
-
Editors: W.C. Dewey, M. Edington, R.J.M. Fry, E.J. Hall and G.F. Whitmore. Academic Press Inc., San Diego
-
[5] Brown, J.M. and Lemmon, M.J. Fractionation increases the anti-tumor effect of adding a hypoxic cytotoxin to irradiation. In: Radiation Research, A Twentieth-Century Perspective, pp. 807-812. Editors: W.C. Dewey, M. Edington, R.J.M. Fry, E.J. Hall and G.F. Whitmore. Academic Press Inc., San Diego, 1991.
-
(1991)
Radiation Research, A Twentieth-Century Perspective
, pp. 807-812
-
-
Brown, J.M.1
Lemmon, M.J.2
-
6
-
-
0027288316
-
SR4233 (Tirapazamine): A new anticancer drug exploiting hypoxia in solid tumours
-
[6] Brown, J.M. SR4233 (Tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours. Br. J. Cancer 67: 1163-1170, 1993.
-
(1993)
Br. J. Cancer
, vol.67
, pp. 1163-1170
-
-
Brown, J.M.1
-
7
-
-
0024557638
-
Liver, spleen, and vessels: Preliminary clinical results of CT with perfluorooctylbromide
-
[7] Bruneton, J.N., Falewée, M.N., François, E., Cambon, P., Philip, C., Riess, J.G., Balu-Maestro, C. and Rogopoulos, A. Liver, spleen, and vessels: preliminary clinical results of CT with perfluorooctylbromide. Radiology 170: 179-183, 1989.
-
(1989)
Radiology
, vol.170
, pp. 179-183
-
-
Bruneton, J.N.1
Falewée, M.N.2
François, E.3
Cambon, P.4
Philip, C.5
Riess, J.G.6
Balu-Maestro, C.7
Rogopoulos, A.8
-
8
-
-
85047696164
-
Tissue NAD levels and the response to irradiation or cytotoxic drugs
-
[8] Calcutt, G., Ting, S.M. and Preece, A.W. Tissue NAD levels and the response to irradiation or cytotoxic drugs. Br. J. Cancer 24: 380-388, 1970.
-
(1970)
Br. J. Cancer
, vol.24
, pp. 380-388
-
-
Calcutt, G.1
Ting, S.M.2
Preece, A.W.3
-
9
-
-
0025264546
-
Effect of nicotinamide on the microregional heterogeneity of oxygen delivery within a murine tumor
-
[9] Chaplin, D.J., Horsman, M.R. and Trotter, M.J. Effect of nicotinamide on the microregional heterogeneity of oxygen delivery within a murine tumor. J. Natl. Cancer Inst. 82: 672-676, 1990.
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 672-676
-
-
Chaplin, D.J.1
Horsman, M.R.2
Trotter, M.J.3
-
10
-
-
0026098826
-
Nicotinamide, Fluosol DA and carbogen: A strategy to reoxygenate acutely and chronically hypoxic cell in vivo
-
[10] Chaplin, D.J., Horsman, M.R. and Aoki, D.S. Nicotinamide, Fluosol DA and carbogen: a strategy to reoxygenate acutely and chronically hypoxic cell in vivo. Br. J. Cancer 63: 109-113, 1991.
-
(1991)
Br. J. Cancer
, vol.63
, pp. 109-113
-
-
Chaplin, D.J.1
Horsman, M.R.2
Aoki, D.S.3
-
11
-
-
0022469972
-
Acute hypoxia in tumors; implications for modifiers of radiation effects
-
[11] Chaplin, D.J. Acute hypoxia in tumors; implications for modifiers of radiation effects. Int. J. Radiat. Oncol. Biol. Phys. 12: 1279-1282, 1986.
-
(1986)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.12
, pp. 1279-1282
-
-
Chaplin, D.J.1
-
12
-
-
0025968029
-
Measurement of tumor hypoxia by invasive and non-invasive procedures: A review of recent clinical studies. Radiother
-
[12] Chapman, J.D. Measurement of tumor hypoxia by invasive and non-invasive procedures: a review of recent clinical studies. Radiother. Oncol. Suppl. 20: 13-19, 1991.
-
(1991)
Oncol.
, vol.20
, Issue.SUPPL.
, pp. 13-19
-
-
Chapman, J.D.1
-
13
-
-
0028200683
-
Muscle cramping in phase I clinical trials of tirapazamine (SR4233) with and without radiation
-
[13] Doherty, N., Hancock, S.L., Kaye, S., Coleman, C.N., Shulman, L., Marquez, C., Mariscal, C., Rampling, R., Senan, S. and Roemeling, R.V. Muscle cramping in phase I clinical trials of tirapazamine (SR4233) with and without radiation. Int. J. Radiat. Oncol. Biol. Phys. 29: 379-382, 1994.
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 379-382
-
-
Doherty, N.1
Hancock, S.L.2
Kaye, S.3
Coleman, C.N.4
Shulman, L.5
Marquez, C.6
Mariscal, C.7
Rampling, R.8
Senan, S.9
Roemeling, R.V.10
-
14
-
-
0028079669
-
Comparison of the enhancement of tumor responses to fractionated irradiation by SR 4233 (tirapazamine) and by nicotinamide with carbogen
-
[14] Dorie, M.J., Menke, D. and Brown, J.M. Comparison of the enhancement of tumor responses to fractionated irradiation by SR 4233 (tirapazamine) and by nicotinamide with carbogen. Int. J. Radiat. Oncol. Biol. Phys. 28: 145-150, 1993.
-
(1993)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.28
, pp. 145-150
-
-
Dorie, M.J.1
Menke, D.2
Brown, J.M.3
-
15
-
-
0017749125
-
Measurement of RBE, OER and recovery of potentially lethal damage of a 645 MeV helium ion beam using EMT6 cells
-
[15] Guichard, M., Lachet, B. and Malaise, E.P. Measurement of RBE, OER and recovery of potentially lethal damage of a 645 MeV helium ion beam using EMT6 cells. Radiat. Res. 71: 413-420, 1977.
-
(1977)
Radiat. Res.
, vol.71
, pp. 413-420
-
-
Guichard, M.1
Lachet, B.2
Malaise, E.P.3
-
16
-
-
0020525454
-
Radiosensitivity of four human tumor xenografts. Influence of hypoxia and cell-cell contact
-
[16] Guichard, M., Dertinger, H. and Malaise, E.P. Radiosensitivity of four human tumor xenografts. Influence of hypoxia and cell-cell contact. Radiat. Res. 95: 602-609, 1983.
-
(1983)
Radiat. Res.
, vol.95
, pp. 602-609
-
-
Guichard, M.1
Dertinger, H.2
Malaise, E.P.3
-
17
-
-
0001439690
-
New trends for improving radiation sensitivity by counteracting chronic and acute hypoxia
-
[17] Guichard, M. and Lartigau, E. New trends for improving radiation sensitivity by counteracting chronic and acute hypoxia. Adv. Radiat. Biol. 18: 123-147, 1994.
-
(1994)
Adv. Radiat. Biol.
, vol.18
, pp. 123-147
-
-
Guichard, M.1
Lartigau, E.2
-
19
-
-
0023682830
-
Mechanism of action of the selective tumor radiosensitizer nicotinamide
-
[19] Horsman, M.R., Brown, J.M., Hirst, V.K., Lemmon, M.J., Wood, P.J., Dunphy, E.P. and Overgaard, J. Mechanism of action of the selective tumor radiosensitizer nicotinamide. Int. J. Radiat. Oncol. Biol. Phys. 15: 685-690, 1988.
-
(1988)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.15
, pp. 685-690
-
-
Horsman, M.R.1
Brown, J.M.2
Hirst, V.K.3
Lemmon, M.J.4
Wood, P.J.5
Dunphy, E.P.6
Overgaard, J.7
-
20
-
-
0024563098
-
Tumor radiosensitization by nicotinamide: A result of improved perfusion and oxygenation
-
[20] Horsman, M.R., Chaplin, D.J. and Brown, J.M. Tumor radiosensitization by nicotinamide: a result of improved perfusion and oxygenation. Radiat. Res. 118: 139-150, 1989.
-
(1989)
Radiat. Res.
, vol.118
, pp. 139-150
-
-
Horsman, M.R.1
Chaplin, D.J.2
Brown, J.M.3
-
21
-
-
0027254194
-
Nicotinamide pharmacokinetics in humans and mice: A comparative assessment and the implications for radiotherapy
-
[21] Horsman, M.R., Hoyer, M., Honess, D.J., Dennis, I.F. and Overgaard, J. Nicotinamide pharmacokinetics in humans and mice: a comparative assessment and the implications for radiotherapy. Radiother. Oncol. 27: 131-139, 1993.
-
(1993)
Radiother. Oncol.
, vol.27
, pp. 131-139
-
-
Horsman, M.R.1
Hoyer, M.2
Honess, D.J.3
Dennis, I.F.4
Overgaard, J.5
-
22
-
-
0025939872
-
A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments
-
[22] Kjellen, E., Joiner, M.C., Collier, J.M., Johns, H. and Rojas, A. A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments. Radiother. Oncol. 22: 81-91, 1991.
-
(1991)
Radiother. Oncol.
, vol.22
, pp. 81-91
-
-
Kjellen, E.1
Joiner, M.C.2
Collier, J.M.3
Johns, H.4
Rojas, A.5
-
23
-
-
0026687291
-
The effect of the hypoxic cell drug SR-4233 alone or combined with the ionizing radiations on two human tumor cell lines having different radiosensitivity
-
[23] Lambin, P., Guichard, M., Chavaudra, N. and Malaise, E.P. The effect of the hypoxic cell drug SR-4233 alone or combined with the ionizing radiations on two human tumor cell lines having different radiosensitivity. Radiother. Oncol. 24: 201-204, 1992.
-
(1992)
Radiother. Oncol.
, vol.24
, pp. 201-204
-
-
Lambin, P.1
Guichard, M.2
Chavaudra, N.3
Malaise, E.P.4
-
24
-
-
0030018650
-
The effect of tirapazamine (SR-4233) alone or combined with chemotherapeutic agents on xenografted human tumours
-
[24] Lartigau, E. and Guichard, M. The effect of tirapazamine (SR-4233) alone or combined with chemotherapeutic agents on xenografted human tumours. Br. J. Cancer 73: 1480-1485, 1996.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 1480-1485
-
-
Lartigau, E.1
Guichard, M.2
-
25
-
-
0021276479
-
Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data
-
[25] Moulder, J.E. and Rockwell, S. Hypoxic fractions of solid tumors: experimental techniques, methods of analysis, and a survey of existing data. Int. J. Radiat. Oncol. Biol. Phys. 10: 695-712, 1984.
-
(1984)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.10
, pp. 695-712
-
-
Moulder, J.E.1
Rockwell, S.2
-
26
-
-
0026665123
-
Development of highly fluid, concentrated and stable fluorocarbon emulsions for diagnosis and therapy
-
[26] Riess, J.G., Dalfors, J.L., Hanna, G.K., Klein, D.H., Krafft, M.P., Pelura, T.J. and Schutt, E.G. Development of highly fluid, concentrated and stable fluorocarbon emulsions for diagnosis and therapy. Biomat. Art. Cells Immob. Biotech. 20: 839-842, 1992.
-
(1992)
Biomat. Art. Cells Immob. Biotech.
, vol.20
, pp. 839-842
-
-
Riess, J.G.1
Dalfors, J.L.2
Hanna, G.K.3
Klein, D.H.4
Krafft, M.P.5
Pelura, T.J.6
Schutt, E.G.7
-
27
-
-
0028410182
-
Highly fluorinated systems for oxygen transport, diagnosis and drug delivery
-
[27] Riess, J.G. Highly fluorinated systems for oxygen transport, diagnosis and drug delivery. Colloids Surfaces A: Physicochem. Eng. Aspects 84: 33-48, 1994.
-
(1994)
Colloids Surfaces A: Physicochem. Eng. Aspects
, vol.84
, pp. 33-48
-
-
Riess, J.G.1
-
28
-
-
0025328583
-
Hypoxic fractions of human tumors xenografted into mice: A review
-
[28] Rockwell, S. and Moulder, J.E. Hypoxic fractions of human tumors xenografted into mice: a review. Int. J. Radiat. Oncol. Biol. Phys. 19: 197-202, 1990.
-
(1990)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.19
, pp. 197-202
-
-
Rockwell, S.1
Moulder, J.E.2
-
29
-
-
0025917891
-
Modulation of tumor oxygenation and radiosensitivity by a perfluorooctylbromide emulsion
-
[29] Rockwell, S., Kelley, M., Irvin, C.G., Hughes, C.S., Porter, E., Yabuky, H. and Fischer, J. Modulation of tumor oxygenation and radiosensitivity by a perfluorooctylbromide emulsion. Radiother. Oncol. 22: 92-98, 1991.
-
(1991)
Radiother. Oncol.
, vol.22
, pp. 92-98
-
-
Rockwell, S.1
Kelley, M.2
Irvin, C.G.3
Hughes, C.S.4
Porter, E.5
Yabuky, H.6
Fischer, J.7
-
30
-
-
0027368549
-
Pharmacokinetics of varying doses of nicotinamide and tumour radiosensitisation with carbogen and nicotinamide: Clinical considerations
-
[30] Rojas, A., Hodgkiss, R.J., Stratford, M.R.L., Dennis, M.F. and Johns, H. Pharmacokinetics of varying doses of nicotinamide and tumour radiosensitisation with carbogen and nicotinamide: clinical considerations. Br. J. Cancer 68: 1115-1121, 1993.
-
(1993)
Br. J. Cancer
, vol.68
, pp. 1115-1121
-
-
Rojas, A.1
Hodgkiss, R.J.2
Stratford, M.R.L.3
Dennis, M.F.4
Johns, H.5
-
31
-
-
0027453666
-
Nicotinamide and carbogen: Major effect on the radiosensitivity of EMT6 and HRT18 tumours
-
[31] Simon, J.M., Lartigau, E. and Guichard, M. Nicotinamide and carbogen: major effect on the radiosensitivity of EMT6 and HRT18 tumours. Radiother. Oncol. 28: 203-207, 1993.
-
(1993)
Radiother. Oncol.
, vol.28
, pp. 203-207
-
-
Simon, J.M.1
Lartigau, E.2
Guichard, M.3
-
32
-
-
0029878416
-
Comparison of two techniques for detecting tumour hypoxia: A fluorescent immunochemical method and an in vitro colony assay
-
[32] Stern, S., Hodgkiss, R.J. and Guichard, M. Comparison of two techniques for detecting tumour hypoxia: a fluorescent immunochemical method and an in vitro colony assay. Radiother. Oncol. 39: 129-135, 1996.
-
(1996)
Radiother. Oncol.
, vol.39
, pp. 129-135
-
-
Stern, S.1
Hodgkiss, R.J.2
Guichard, M.3
-
33
-
-
0025162889
-
Influence of schedule dose, and volume of administration of perfluorochemical emulsion on tumor response to radiation therapy
-
[33] Teicher, B.A., Herman, T.S. and Jones, S.M. Influence of schedule dose, and volume of administration of perfluorochemical emulsion on tumor response to radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 19: 945-951, 1990.
-
(1990)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.19
, pp. 945-951
-
-
Teicher, B.A.1
Herman, T.S.2
Jones, S.M.3
-
34
-
-
0028132666
-
Reduced oxygenation in a rat mammary carcinoma after chemo-or radiation therapy and reoxygenation with perflubron emulsion/carbogen breathing
-
[34] Teicher, B.A., Sotomayor, E.A., Dupuis, N.P., Kusumoto, T. and Menon, K. Reduced oxygenation in a rat mammary carcinoma after chemo-or radiation therapy and reoxygenation with perflubron emulsion/carbogen breathing. J. Cancer Res. Clin. Oncol. 120: 593-598, 1994.
-
(1994)
J. Cancer Res. Clin. Oncol.
, vol.120
, pp. 593-598
-
-
Teicher, B.A.1
Sotomayor, E.A.2
Dupuis, N.P.3
Kusumoto, T.4
Menon, K.5
-
36
-
-
0029077492
-
Tumour oxygenation, radiosensitivity, and necrosis before and/or after nicotinamide, carbogen and perflubron emulsion administration
-
[36] Thomas, C.D., Prade, M. and Guichard, M. Tumour oxygenation, radiosensitivity, and necrosis before and/or after nicotinamide, carbogen and perflubron emulsion administration. Int. J. Radiat. Biol. 67: 597-606, 1995.
-
(1995)
Int. J. Radiat. Biol.
, vol.67
, pp. 597-606
-
-
Thomas, C.D.1
Prade, M.2
Guichard, M.3
-
37
-
-
0026026246
-
Influence of the 100% w/v perfluorooctyl bromide (PFOB) emulsion dose on tumour radiosensitivity
-
[37] Thomas, C., Riess, J. and Guichard, M. Influence of the 100% w/v perfluorooctyl bromide (PFOB) emulsion dose on tumour radiosensitivity. Int. J. Radiat. Biol. 59: 433-445, 1991.
-
(1991)
Int. J. Radiat. Biol.
, vol.59
, pp. 433-445
-
-
Thomas, C.1
Riess, J.2
Guichard, M.3
-
38
-
-
0024365790
-
The use of fluorescent probes to identify regions of transient perfusion in murine tumors
-
[38] Trotter, M.J., Chaplin, D.J., Durand, R.E. and Olive, P.L. The use of fluorescent probes to identify regions of transient perfusion in murine tumors. Int. J. Radiat. Oncol. Biol. Phys. 16: 931-934, 1989.
-
(1989)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.16
, pp. 931-934
-
-
Trotter, M.J.1
Chaplin, D.J.2
Durand, R.E.3
Olive, P.L.4
-
39
-
-
0025329088
-
Oxygenation of human tumors
-
[39] Vaupel, P. Oxygenation of human tumors. Strahlenther Onkol. 166: 377-386, 1990.
-
(1990)
Strahlenther Onkol.
, vol.166
, pp. 377-386
-
-
Vaupel, P.1
-
40
-
-
0027258630
-
Radiosensitivity, blood perfusion and tumour oxygenation after perflubron emulsion injection
-
[40] Vitu-Loas, L., Thomas, C., Chavaudra, N. and Guichard, M. Radiosensitivity, blood perfusion and tumour oxygenation after perflubron emulsion injection. Radiother. Oncol. 27: 149-155, 1993.
-
(1993)
Radiother. Oncol.
, vol.27
, pp. 149-155
-
-
Vitu-Loas, L.1
Thomas, C.2
Chavaudra, N.3
Guichard, M.4
-
41
-
-
0022493495
-
SR4233: A new bioreductive agent with high selective toxicity for hypoxic mammalian cells
-
[41] Zeman, E.M., Brown, J.M., Lemmon, M.J., Hirst, V.K. and Lee, W.W. SR4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells. Int. J. Radiat. Oncol. Biol. Phys. 12: 1239-1242, 1986.
-
(1986)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.12
, pp. 1239-1242
-
-
Zeman, E.M.1
Brown, J.M.2
Lemmon, M.J.3
Hirst, V.K.4
Lee, W.W.5
-
42
-
-
0023750547
-
Enhancement of radiation-induced tumor cell killing by the hypoxic cell toxin SR4233
-
[42] Zeman, E.M., Hirst, V.K., Lemmon, M.J. and Brown, J.M. Enhancement of radiation-induced tumor cell killing by the hypoxic cell toxin SR4233. Radiother. Oncol. 12: 209-218, 1988.
-
(1988)
Radiother. Oncol.
, vol.12
, pp. 209-218
-
-
Zeman, E.M.1
Hirst, V.K.2
Lemmon, M.J.3
Brown, J.M.4
|