Intrinsic deuterium kinetic isotope effects in glutamate mutase measured by an intramolecular competition experiment

Angewandte Chemie - International Edition

Volumn 46, Issue 44, 2007, Pages 8455-8459

  Yoon, Min ^a   Kalli, Anastasia ^a   Lee, Hyang Yeol ^a   Håkansson, Kristina ^a   Marsh, E Neil G ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Cobalamins; Coenzyme B12; Enzymes; Mass spectrometry; Radicals

Indexed keywords

COBALAMINS; COENZYME B12; GLUTAMATE MUTASE; HYDROGEN TRANSFER; KINETIC ISOTOPE EFFECTS;

COENZYMES; DEUTERIUM; ELECTRON ENERGY LEVELS; ELECTRON TRANSITIONS; MASS SPECTROMETRY; MOLECULAR DYNAMICS; MOLECULAR MODELING;

ENZYME ACTIVITY;

2 METHYLASPARTIC ACID; 2-METHYLASPARTIC ACID; COBAMAMIDE; DEUTERIUM; DRUG DERIVATIVE; ENZYME; HYDROGEN; METHYLASPARTATE MUTASE; MUTASE; N METHYLASPARTIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; BIOTECHNOLOGY; CATALYSIS; CHEMICAL MODEL; CHEMISTRY; CONFORMATION; ELECTROSPRAY MASS SPECTROMETRY; KINETICS; METHODOLOGY; TEMPERATURE;

BINDING, COMPETITIVE; BIOTECHNOLOGY; CATALYSIS; CHEMISTRY; COBAMIDES; DEUTERIUM; ENZYMES; HYDROGEN; INTRAMOLECULAR TRANSFERASES; KINETICS; MODELS, CHEMICAL; MOLECULAR CONFORMATION; N-METHYLASPARTATE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TEMPERATURE;

EID: 36148974695     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200702448     Document Type: Article

References (39)

1. W. W. Cleland, CRC Crit. Rev. Biochem. 1982, 13, 385-428.
2. W. W. Cleland in Isotopes in Organic Chemistry, Vol. 7 (Eds.: E. Buncel, C. C. Lee), Elsevier, Amsterdam 1987.
3. V. L. Schramm, Curr. Opin. Chem. Biol. 2001, 5, 556-563.
4. Z. D. Nagel, J. P. Klinman, Chem. Rev. 2006, 106, 3095-3118.
5. P. A. Frey, A. D. Hegerman, G. H. Reed, Chem. Rev. 2006, 106, 3302-3316.
6. R. Banerjee, Chem. Rev. 2003, 103, 2083-2094.
7. E. N. G. Marsh, C. L. Drennan, Curr. Opin. Chem. Biol. 2001, 5, 499-505.
8. P. A. Frey, Annu. Rev. Biochem. 2001, 70, 121-148.
9. R. Banerjee, Biochemistry 2001, 40, 6191-96198.
10. E. N. G. Marsh, Bioorg. Chem. 2000, 28, 176-189.
11. E. N. G. Marsh, D. P. Ballou, Biochemistry 1998, 37, 11864-11872.
12. H.-W. Chih, E. N. G. Marsh, Biochemistry 2001, 40, 13060-13067.
13. M.-C. Cheng, E. N. G. Marsh, Biochemistry 2004, 43, 2155-2158.
14. M.-C. Cheng, E. N. G. Marsh, Biochemistry 2005, 44, 2686-2691.
15. M. C. Cheng, E. N. G. Marsh, Biochemistry 2007, 46, 883-889.
16. S. S. Licht, C. C. Lawrence, J. Stubbe, Biochemistry 1999, 38, 1234-1242.
17. R. Padmakumar, R. Banerjee, Biochemistry 1997, 36, 3713-3718.
18. V. Bandarian, G. H. Reed, Biochemistry 2000, 39, 12069-12075.
19. S. Chowdhury, R. Banerjee, J. Am. Chem. Soc. 2000, 122, 5417-5418.
20. D. E. Holloway, E. N. G. Marsh, J. Biol. Chem. 1994, 269, 20425-20430.
21. D. A. Weisblat, B. M. Babior, J. Biol. Chem. 1971, 246, 6064-6071.
22. M. K. Essenberg, P. A. Frey, R. H. Abeles, J. Am. Chem. Soc. 1971, 93, 1242-1251.
23. K. R. Iyer, J. P. Jones, J. F. Darbyshire, W. F. Trager, Biochemistry 1997, 36, 7136-7143.
24. H.-Y. Lee, M. Yoon, E. N. G. Marsh, Tetrahedron 2007, 63, 4663-4668.
25. H. P. Chen, E. N. G. Marsh, Biochemistry 1997, 36, 14939-14945.
26. H. W. Chin, E. N. G. Marsh, Biochemistry 1999, 38, 13684-13691.
27. F. He, C. L. Hendrickson, A. G. Marshall, Anal. Chem. 2001, 73, 647-650.
28. S. D. H. Shi, C. L. Hendrickson, A. G. Marshall, Proc. Natl. Acad. Sci. USA 1998, 95, 11532-11537.
29. E. N. G. Marsh, Biochemistry 1995, 34, 7542-7547.
30. K. M. Doll, B. R. Bender, R. G. Finke, J. Am. Chem. Soc. 2003, 125, 10877-10884.
31. K. M. Doll, R. G. Finke, Inorg. Chem. 2003, 42, 4849-4856.
32. L. Masgrau, A. Roujeinikova, L. O. Johannissen, P. Hothi, J. Basran, K. E. Ranaghan, A. J. Mulholland, M. J. Sutcliffe, N. S. Scrutton, D. Leys, Science 2006, 312, 237-241.
33. M. J. Sutcliffe, N. S. Scrutton, Eur. J. Biochem. 2002, 269, 3096-3102.
34. A. Kohen, R. Cannio, S. Bartolucci, J. P. Klinman, Nature 1999, 399, 496-499.
35. J. Suhnel, R. L. Schowen in Enzyme Mechanism from Isotope Effects (Ed.: P. F. Cook), CRC, Boca Raton, FL, 1991, pp. 3-35.
36. N. J. Turro, Acc. Chem. Res. 2000, 33, 637-646.
37. T. T. Harkins, C. B. Grissom, Science 1994, 263, 958-960.
38. C. B. Grissom, Chem. Rev. 1995, 95, 3-24.
39. J. Yang, J. J. Mo, J. T. Adamson, K. Hakansson, Anal. Chem. 2005, 77, 1876-1882.