-
1
-
-
14944385553
-
Global cancer statistics 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 2005, 55:74-108.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
3
-
-
0032915392
-
Epidermal growth factor receptors: Critical mediators of multiple receptor pathways
-
Hackel PO, Zwick E, Prenzel N, Ullrich A: Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr Opin Cell Biol 1999, 11:184-189.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 184-189
-
-
Hackel, P.O.1
Zwick, E.2
Prenzel, N.3
Ullrich, A.4
-
4
-
-
14644392200
-
Epidermal growth factor receptor coexpression modulates susceptibility to herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation
-
Diermeier S, Horvath G, Knuechel-Clarke R, et al.: Epidermal growth factor receptor coexpression modulates susceptibility to herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation. Exp Cell Res 2005, 304:604-619.
-
(2005)
Exp Cell Res
, vol.304
, pp. 604-619
-
-
Diermeier, S.1
Horvath, G.2
Knuechel-Clarke, R.3
-
5
-
-
0035447953
-
Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma: Implications for a standardized scoring system
-
Goldstein NS, Armin M: Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma: implications for a standardized scoring system. Cancer 2001, 92:1331-1346.
-
(2001)
Cancer
, vol.92
, pp. 1331-1346
-
-
Goldstein, N.S.1
Armin, M.2
-
6
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, Normanno N: Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995, 19:183-232.
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
7
-
-
0027415146
-
The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer
-
Mayer A, Takimoto M, Fritz E, et al.: The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer. Cancer 1993, 71:2454-2460.
-
(1993)
Cancer
, vol.71
, pp. 2454-2460
-
-
Mayer, A.1
Takimoto, M.2
Fritz, E.3
-
8
-
-
0026471016
-
Prognostic markers of colorectal cancer: An evaluation of DNA content, epidermal growth factor receptor, and Ki-67
-
Hemming AW, Davis NL, Kluftinger A, et al.: Prognostic markers of colorectal cancer: an evaluation of DNA content, epidermal growth factor receptor, and Ki-67. J Surg Oncol 1992, 51:147-152.
-
(1992)
J Surg Oncol
, vol.51
, pp. 147-152
-
-
Hemming, A.W.1
Davis, N.L.2
Kluftinger, A.3
-
9
-
-
0027442527
-
Therapeutic potential of chimeric and murine anti-(epidermal growth factor receptor) antibodies in a metastasis model for human melanoma
-
Naramura M, Gillies SD, Mendelsohn J, et al.: Therapeutic potential of chimeric and murine anti-(epidermal growth factor receptor) antibodies in a metastasis model for human melanoma. Cancer Immunol Immunother 1993, 37:343-349.
-
(1993)
Cancer Immunol Immunother
, vol.37
, pp. 343-349
-
-
Naramura, M.1
Gillies, S.D.2
Mendelsohn, J.3
-
10
-
-
0002823211
-
Cetuximab (IMC-C225) plus irinotecan (CPT-11) is active in CPT-11-refractory colorectal cancer (CRC) that expresses epidermal growth factor receptor (EGFR)
-
Saltz L, Rubin M, Hochster H, et al.: Cetuximab (IMC-C225) plus irinotecan (CPT-11) is active in CPT- 11-refractory colorectal cancer (CRC) that expresses epidermal growth factor receptor (EGFR). Proc Am Soc Clin Oncol 2001, 20:3.
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
, pp. 3
-
-
Saltz, L.1
Rubin, M.2
Hochster, H.3
-
11
-
-
2142641698
-
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
-
Saltz LB, Meropol NJ, Loehrer PJ Sr, et al.: Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004, 22:1201-1208.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1201-1208
-
-
Saltz, L.B.1
Meropol, N.J.2
Loehrer Sr., P.J.3
-
12
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan- refractory metastatic colorectal cancer
-
Cunningham D, Humblet Y, Siena S, et al.: Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan- refractory metastatic colorectal cancer. N Engl J Med 2004, 351:337-345.
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
13
-
-
3543053772
-
Activity of cetuximab in patients with colorectal cancer refractory to both irinotecan and oxaliplatin
-
Lenz HJ, Mayer RJ, Gold PJ, et al.: Activity of cetuximab in patients with colorectal cancer refractory to both irinotecan and oxaliplatin. Proc Am Soc Clin Oncol 2004, 22:247.
-
(2004)
Proc Am Soc Clin Oncol
, vol.22
, pp. 247
-
-
Lenz, H.J.1
Mayer, R.J.2
Gold, P.J.3
-
14
-
-
33645551909
-
Cetuximab + FOLFOX 6 as first line therapy for metastatic colorectal cancer
-
Scott J, Dakhil S, Cosgriff T, et al.: Cetuximab + FOLFOX 6 as first line therapy for metastatic colorectal cancer. Proc Am Soc Clin Oncol 2005, 23:3705.
-
(2005)
Proc Am Soc Clin Oncol
, vol.23
, pp. 3705
-
-
Scott, J.1
Dakhil, S.2
Cosgriff, T.3
-
15
-
-
21244475037
-
Randomized phase II trial of cetuximab/bevacizumab/irinotecan (CBI) versus cetuximab/bevacizumab (CB) in irinotecan-refractory colorectal cancer
-
Saltz LB, Lenz H, Kindler H, et al.: Randomized phase II trial of cetuximab/bevacizumab/irinotecan (CBI) versus cetuximab/bevacizumab (CB) in irinotecan-refractory colorectal cancer. Proc Am Soc Clin Oncol 2005, 23:248s.
-
(2005)
Proc Am Soc Clin Oncol
, vol.23
-
-
Saltz, L.B.1
Lenz, H.2
Kindler, H.3
-
17
-
-
23844454976
-
Safety and efficacy of panitumumab monotherapy in patients with metastatic colorectal cancer
-
Malik I, Hecht JR, Patnaik A, et al.: Safety and efficacy of panitumumab monotherapy in patients with metastatic colorectal cancer. Proc Am Soc Clin Oncol 2005, 23:251.
-
(2005)
Proc Am Soc Clin Oncol
, vol.23
, pp. 251
-
-
Malik, I.1
Hecht, J.R.2
Patnaik, A.3
-
18
-
-
22944444890
-
Monoclonal antibodies, immunogenicity, and associated infusion reactions
-
Cheifetz A, Mayer L: Monoclonal antibodies, immunogenicity, and associated infusion reactions. Mt Sinai J Med 2005, 72:250-256.
-
(2005)
Mt Sinai J Med
, vol.72
, pp. 250-256
-
-
Cheifetz, A.1
Mayer, L.2
-
20
-
-
0033762498
-
The EGF receptor-an essential regulator of multiple epidermal functions
-
Jost M, Kari C, Rodeck U: The EGF receptor-an essential regulator of multiple epidermal functions. Eur J Dermatol 2000, 10:505-510.
-
(2000)
Eur J Dermatol
, vol.10
, pp. 505-510
-
-
Jost, M.1
Kari, C.2
Rodeck, U.3
-
21
-
-
24044500971
-
Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors
-
Segaert S, Van Cutsem E: Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors. Ann Oncol 2005, 16:1425-1433.
-
(2005)
Ann Oncol
, vol.16
, pp. 1425-1433
-
-
Segaert, S.1
Van Cutsem, E.2
-
22
-
-
0035724536
-
Cutaneous sideeffects in cancer patients treated with the antiepidermal growth factor receptor antibody C225
-
Busam KJ, Capodieci P, Motzer R, et al.: Cutaneous sideeffects in cancer patients treated with the antiepidermal growth factor receptor antibody C225. Br J Dermatol 2001, 144:1169-1176.
-
(2001)
Br J Dermatol
, vol.144
, pp. 1169-1176
-
-
Busam, K.J.1
Capodieci, P.2
Motzer, R.3
-
23
-
-
0038306878
-
Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation
-
Mascia F, Mariani V, Girolomoni G, Pastore S: Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation. Am J Pathol 2003, 163:303-312.
-
(2003)
Am J Pathol
, vol.163
, pp. 303-312
-
-
Mascia, F.1
Mariani, V.2
Girolomoni, G.3
Pastore, S.4
-
24
-
-
25444456158
-
Efficacy of treatment with tetracyclines to prevent acneiform eruption secondary to cetuximab therapy
-
Micantonio T, Fargnoli MC, Ricevuto E, et al.: Efficacy of treatment with tetracyclines to prevent acneiform eruption secondary to cetuximab therapy. Arch Dermatol 2005, 141:1173-1174.
-
(2005)
Arch Dermatol
, vol.141
, pp. 1173-1174
-
-
Micantonio, T.1
Fargnoli, M.C.2
Ricevuto, E.3
-
25
-
-
26244449709
-
Successful treatment with oral isotretinoin of acneiform skin lesions associated with cetuximab therapy
-
Gutzmer R, Werfel T, Mao R, et al.: Successful treatment with oral isotretinoin of acneiform skin lesions associated with cetuximab therapy. Br J Dermatol 2005, 153:849-851.
-
(2005)
Br J Dermatol
, vol.153
, pp. 849-851
-
-
Gutzmer, R.1
Werfel, T.2
Mao, R.3
-
26
-
-
31344476048
-
Tetracyclines: Nonantibiotic properties and their clinical implications
-
Sapadin AN, Fleischmajer R: Tetracyclines: nonantibiotic properties and their clinical implications. J Am Acad Dermatol 2006, 54:258-265.
-
(2006)
J Am Acad Dermatol
, vol.54
, pp. 258-265
-
-
Sapadin, A.N.1
Fleischmajer, R.2
-
27
-
-
23844555670
-
Cetuximab therapy and symptomatic hypomagnesemia
-
Schrag D, Chung KY, Flombaum C, Saltz L: Cetuximab therapy and symptomatic hypomagnesemia. J Natl Cancer Inst 2005, 97:1221-1224.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1221-1224
-
-
Schrag, D.1
Chung, K.Y.2
Flombaum, C.3
Saltz, L.4
-
28
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al.: Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004, 350:2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
29
-
-
21244481589
-
High-dose bevacizumab improves survival when combined with FOLFOX4 in patients with previously treated advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group (ECOG) Study E3200
-
Giantonio BJ, Catalano PJ, Meropol NJ, et al.: High-dose bevacizumab improves survival when combined with FOLFOX4 in patients with previously treated advanced colorectal cancer: results from the Eastern Cooperative Oncology Group (ECOG) Study E3200. Proc Am Soc Clin Oncol 2005, 23:1.
-
(2005)
Proc Am Soc Clin Oncol
, vol.23
, pp. 1
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
-
30
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
31
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J: Tumor angiogenesis: therapeutic implications. N Engl J Med 1971, 285:1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
32
-
-
0025141337
-
What is the evidence that tumors are angiogenesis dependent?
-
Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990, 82:4-6.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 4-6
-
-
Folkman, J.1
-
33
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G, Benjamin LE: Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003, 3:401-410.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
34
-
-
0038443099
-
Anti-angiogenic therapy: Rationale, challenges and clinical studies
-
Longo R, Sarmiento R, Fanelli M, et al.: Anti-angiogenic therapy: rationale, challenges and clinical studies. Angiogenesis 2002, 5:237-256.
-
(2002)
Angiogenesis
, vol.5
, pp. 237-256
-
-
Longo, R.1
Sarmiento, R.2
Fanelli, M.3
-
35
-
-
0034979159
-
Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis
-
Dor Y, Porat R, Keshet E: Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis. Am J Physiol Cell Physiol 2001, 280: C1367-1374.
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Dor, Y.1
Porat, R.2
Keshet, E.3
-
36
-
-
2342426506
-
Hypoxia and hypoxia inducible factors (HIF) as important regulators of tumor physiology
-
Acker T, Plate KH: Hypoxia and hypoxia inducible factors (HIF) as important regulators of tumor physiology. Cancer Treat Res 2004, 117:219-248.
-
(2004)
Cancer Treat Res
, vol.117
, pp. 219-248
-
-
Acker, T.1
Plate, K.H.2
-
38
-
-
0025999033
-
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
-
Tischer E, Mitchell R, Hartman T, et al.: The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem 1991, 266:11947-11954.
-
(1991)
J Biol Chem
, vol.266
, pp. 11947-11954
-
-
Tischer, E.1
Mitchell, R.2
Hartman, T.3
-
39
-
-
0025259592
-
Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family
-
Shibuya M, Yamaguchi S, Yamane A, et al.: Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 1990, 5:519-524.
-
(1990)
Oncogene
, vol.5
, pp. 519-524
-
-
Shibuya, M.1
Yamaguchi, S.2
Yamane, A.3
-
40
-
-
0026702970
-
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
-
Terman BI, Dougher-Vermazen M, Carrion ME, et al.: Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 1992, 187:1579-1586.
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 1579-1586
-
-
Terman, B.I.1
Dougher-Vermazen, M.2
Carrion, M.E.3
-
41
-
-
0025998533
-
A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit
-
Matthews W, Jordan CT, Gavin M, et al.: A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc Natl Acad Sci U S A 1991, 88:9026-9030.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 9026-9030
-
-
Matthews, W.1
Jordan, C.T.2
Gavin, M.3
-
42
-
-
0027380823
-
Two human FLT4 receptor tyrosine kinase isoforms with distinct carboxy terminal tails are produced by alternative processing of primary transcripts
-
Pajusola K, Aprelikova O, Armstrong E, et al.: Two human FLT4 receptor tyrosine kinase isoforms with distinct carboxy terminal tails are produced by alternative processing of primary transcripts. Oncogene 1993, 8:2931-2937.
-
(1993)
Oncogene
, vol.8
, pp. 2931-2937
-
-
Pajusola, K.1
Aprelikova, O.2
Armstrong, E.3
-
43
-
-
0027232628
-
The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor
-
Galland F, Karamysheva A, Pebusque MJ, et al.: The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor. Oncogene 1993, 8:1233-1240.
-
(1993)
Oncogene
, vol.8
, pp. 1233-1240
-
-
Galland, F.1
Karamysheva, A.2
Pebusque, M.J.3
-
44
-
-
0035114105
-
Involvement of flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis
-
Hiratsuka S, Maru Y, Okada A, et al.: Involvement of flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis. Cancer Res 2001, 61:1207-1213.
-
(2001)
Cancer Res
, vol.61
, pp. 1207-1213
-
-
Hiratsuka, S.1
Maru, Y.2
Okada, A.3
-
45
-
-
0036842215
-
Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
-
Dvorak HF: Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 2002, 20:4368-4380.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4368-4380
-
-
Dvorak, H.F.1
-
46
-
-
0035920244
-
Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinasedependent pathways
-
Zeng H, Dvorak HF, Mukhopadhyay D: Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinasedependent pathways. J Biol Chem 2001, 276:26969-26979.
-
(2001)
J Biol Chem
, vol.276
, pp. 26969-26979
-
-
Zeng, H.1
Dvorak, H.F.2
Mukhopadhyay, D.3
-
47
-
-
0032933883
-
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
-
Valtola R, Salven P, Heikkila P, et al.: VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer. Am J Pathol 1999, 154:1381-1390.
-
(1999)
Am J Pathol
, vol.154
, pp. 1381-1390
-
-
Valtola, R.1
Salven, P.2
Heikkila, P.3
-
48
-
-
0029562097
-
Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs
-
Kitsukawa T, Shimono A, Kawakami A, et al.: Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development 1995, 121:4309-4318.
-
(1995)
Development
, vol.121
, pp. 4309-4318
-
-
Kitsukawa, T.1
Shimono, A.2
Kawakami, A.3
-
49
-
-
0037133617
-
Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis
-
Takashima S, Kitakaze M, Asakura M, et al.: Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci U S A 2002, 99:3657-3662.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3657-3662
-
-
Takashima, S.1
Kitakaze, M.2
Asakura, M.3
-
50
-
-
0028803509
-
Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
-
Alon T, Hemo I, Itin A, et al.: Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med 1995, 1:1024-1028.
-
(1995)
Nat Med
, vol.1
, pp. 1024-1028
-
-
Alon, T.1
Hemo, I.2
Itin, A.3
-
51
-
-
0035895711
-
Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
-
Zachary I, Gliki G: Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc Res 2001, 49:568-581.
-
(2001)
Cardiovasc Res
, vol.49
, pp. 568-581
-
-
Zachary, I.1
Gliki, G.2
-
52
-
-
0035966004
-
Vascular endothelial growth factor induction of the angiogenic phenotype requires Ras activation
-
Meadows KN, Bryant P, Pumiglia K: Vascular endothelial growth factor induction of the angiogenic phenotype requires Ras activation. J Biol Chem 2001, 276:49289-49298.
-
(2001)
J Biol Chem
, vol.276
, pp. 49289-49298
-
-
Meadows, K.N.1
Bryant, P.2
Pumiglia, K.3
-
53
-
-
0031039243
-
The biology of vascular endothelial growth factor
-
Ferrara N, Davis-Smyth T: The biology of vascular endothelial growth factor. Endocr Rev 1997, 18:4-25.
-
(1997)
Endocr Rev
, vol.18
, pp. 4-25
-
-
Ferrara, N.1
Davis-Smyth, T.2
-
54
-
-
0034979275
-
Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor
-
Zachary I: Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor. Am J Physiol Cell Physiol 2001, 280:C1375-1386.
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Zachary, I.1
-
55
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak HF, Brown LF, Detmar M, Dvorak AM: Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995, 146:1029-1039.
-
(1995)
Am J Pathol
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
56
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J, et al.: Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993, 362:841-844.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
-
57
-
-
0035253586
-
Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: Pharmacologic and long-term safety data
-
Margolin K, Gordon MS, Holmgren E, et al.: Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: pharmacologic and long-term safety data. J Clin Oncol 2001, 19:851-856.
-
(2001)
J Clin Oncol
, vol.19
, pp. 851-856
-
-
Margolin, K.1
Gordon, M.S.2
Holmgren, E.3
-
58
-
-
0035253739
-
Phase i safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
-
Gordon MS, Margolin K, Talpaz M, et al.: Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J Clin Oncol 2001, 19:843-850.
-
(2001)
J Clin Oncol
, vol.19
, pp. 843-850
-
-
Gordon, M.S.1
Margolin, K.2
Talpaz, M.3
-
59
-
-
0037208589
-
Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
-
Kabbinavar F, Hurwitz HI, Fehrenbacher L, et al.: Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003, 21:60-65.
-
(2003)
J Clin Oncol
, vol.21
, pp. 60-65
-
-
Kabbinavar, F.1
Hurwitz, H.I.2
Fehrenbacher, L.3
-
60
-
-
28344438302
-
Arterial thromboembolic events in a pooled analysis of 5 randomized, controlled trials of bevacizumab with chemotherapy
-
Skillings JR, Johnson DH, Miller K, et al.: Arterial thromboembolic events in a pooled analysis of 5 randomized, controlled trials of bevacizumab with chemotherapy. J Clin Oncol 2005, 23:3019.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3019
-
-
Skillings, J.R.1
Johnson, D.H.2
Miller, K.3
-
61
-
-
20544478429
-
Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial
-
Kabbinavar FF, Schulz J, McCleod M, et al.: Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial. J Clin Oncol 2005, 23:3697-3705.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3697-3705
-
-
Kabbinavar, F.F.1
Schulz, J.2
McCleod, M.3
-
62
-
-
20544471876
-
Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
-
Kabbinavar FF, Hambleton J, Mass RD, et al.: Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 2005, 23:3706-3712.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
-
63
-
-
0038460302
-
The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: The JNC 7 report
-
Chobanian AV, Bakris GL, Black HR, et al.: The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 2003, 289:2560-2572.
-
(2003)
JAMA
, vol.289
, pp. 2560-2572
-
-
Chobanian, A.V.1
Bakris, G.L.2
Black, H.R.3
-
64
-
-
18744405611
-
-
San Francisco CA: Genentech
-
Avastin [package insert]. San Francisco, CA: Genentech; 2004. Available at www.avastin.com.
-
(2004)
Avastin [Package Insert]
-
-
-
65
-
-
0031008458
-
Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor- induced angiogenesis
-
Ziche M, Morbidelli L, Choudhuri R, et al.: Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor- induced angiogenesis. J Clin Invest 1997, 99:2625-2634.
-
(1997)
J Clin Invest
, vol.99
, pp. 2625-2634
-
-
Ziche, M.1
Morbidelli, L.2
Choudhuri, R.3
-
67
-
-
0037233310
-
Endothelial damage and angiogenesis in hypertensive patients: Relationship to cardiovascular risk factors and risk factor management
-
Felmeden DC, Spencer CG, Belgore FM, et al.: Endothelial damage and angiogenesis in hypertensive patients: relationship to cardiovascular risk factors and risk factor management. Am J Hypertens 2003, 16:11-20.
-
(2003)
Am J Hypertens
, vol.16
, pp. 11-20
-
-
Felmeden, D.C.1
Spencer, C.G.2
Belgore, F.M.3
-
68
-
-
3242749316
-
The role of VEGF-A in glomerular development and function
-
Eremina V, Quaggin SE: The role of VEGF-A in glomerular development and function. Curr Opin Nephrol Hypertens 2004, 13:9-15.
-
(2004)
Curr Opin Nephrol Hypertens
, vol.13
, pp. 9-15
-
-
Eremina, V.1
Quaggin, S.E.2
-
69
-
-
0032589378
-
VEGF(165) mediates glomerular endothelial repair
-
Ostendorf T, Kunter U, Eitner F, et al.: VEGF(165) mediates glomerular endothelial repair. J Clin Invest 1999, 104:913-923.
-
(1999)
J Clin Invest
, vol.104
, pp. 913-923
-
-
Ostendorf, T.1
Kunter, U.2
Eitner, F.3
-
70
-
-
0034575632
-
The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing
-
Bloch W, Huggel K, Sasaki T, et al.: The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing. Faseb J 2000, 14:2373-2376.
-
(2000)
Faseb J
, vol.14
, pp. 2373-2376
-
-
Bloch, W.1
Huggel, K.2
Sasaki, T.3
-
71
-
-
0032864848
-
Angiogenesis inhibitor TNP-470 inhibits murine cutaneous wound healing
-
Klein SA, Bond SJ, Gupta SC, et al.: Angiogenesis inhibitor TNP-470 inhibits murine cutaneous wound healing. J Surg Res 1999, 82:268-274.
-
(1999)
J Surg Res
, vol.82
, pp. 268-274
-
-
Klein, S.A.1
Bond, S.J.2
Gupta, S.C.3
-
72
-
-
0034600837
-
Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice
-
Streit M, Velasco P, Riccardi L, et al.: Thrombospondin- 1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice. Embo J 2000, 19:3272-3282.
-
(2000)
Embo J
, vol.19
, pp. 3272-3282
-
-
Streit, M.1
Velasco, P.2
Riccardi, L.3
-
73
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson DH, Fehrenbacher L, Novotny WF, et al.: Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2004, 22:2184-2191.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
74
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
Yang JC, Haworth L, Sherry RM, et al.: A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003, 349:427-434.
-
(2003)
N Engl J Med
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
75
-
-
33646780432
-
A randomized phase III trial of paclitaxel versus paclitaxel plus bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer. in
-
Orlando, FL; May 13-17
-
Miller KD, Wang M, Gralow J, et al.: A randomized phase III trial of paclitaxel versus paclitaxel plus bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer. In the Proceedings of the American Society of Clinical Oncology. Orlando, FL; May 13-17, 2005.
-
(2005)
Proceedings of the American Society of Clinical Oncology
-
-
Miller, K.D.1
Wang, M.2
Gralow, J.3
-
76
-
-
24344442899
-
Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab
-
Scappaticci FA, Fehrenbacher L, Cartwright T, et al.: Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab. J Surg Oncol 2005, 91:173-180.
-
(2005)
J Surg Oncol
, vol.91
, pp. 173-180
-
-
Scappaticci, F.A.1
Fehrenbacher, L.2
Cartwright, T.3
-
77
-
-
24644454338
-
Surgical resection after downsizing of colorectal liver metastasis in the era of bevacizumab
-
Ellis LM, Curley SA, Grothey A: Surgical resection after downsizing of colorectal liver metastasis in the era of bevacizumab. J Clin Oncol 2005, 23:4853-4855.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4853-4855
-
-
Ellis, L.M.1
Curley, S.A.2
Grothey, A.3
-
78
-
-
0142121282
-
Bevacizumab, bleeding, thrombosis, and warfarin
-
author reply 3
-
Kilickap S, Abali H, Celik I: Bevacizumab, bleeding, thrombosis, and warfarin. J Clin Oncol 2003, 21:3542,author reply 3.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3542
-
-
Kilickap, S.1
Abali, H.2
Celik, I.3
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