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Volumn 293, Issue 5, 2007, Pages

Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells

Author keywords

Focal adhesion; Rac; Sphingosine 1 phosphate receptor type 1; Transmonolayer electrical resistance

Indexed keywords

CELL PROTEIN; FOCAL ADHESION KINASE; GUANOSINE TRIPHOSPHATASE; HYDROXYL RADICAL; IMMUNOGLOBULIN G; NORPHENAZONE; PAXILLIN; RAC PROTEIN; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE;

EID: 36048961354     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00524.2006     Document Type: Article
Times cited : (7)

References (59)
  • 2
    • 0034614621 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5
    • An S, Zheng Y, Bleu T. Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. J Biol Chem 275: 288-296, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 288-296
    • An, S.1    Zheng, Y.2    Bleu, T.3
  • 5
    • 0033543988 scopus 로고    scopus 로고
    • Vascular endothelial (VE)-cadherin: Only an intercellular glue?
    • Dejana E, Bazzoni G, Lampugnani MG. Vascular endothelial (VE)-cadherin: only an intercellular glue? Exp Cell Res 252: 13-19, 1999.
    • (1999) Exp Cell Res , vol.252 , pp. 13-19
    • Dejana, E.1    Bazzoni, G.2    Lampugnani, M.G.3
  • 6
    • 0029972351 scopus 로고    scopus 로고
    • Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions
    • Del Maschio A, Zanetti A, Corada M, Rival Y, Ruco L, Lampugnani MG, Dejana E. Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions. J Cell Biol 135: 497-510, 1996.
    • (1996) J Cell Biol , vol.135 , pp. 497-510
    • Del Maschio, A.1    Zanetti, A.2    Corada, M.3    Rival, Y.4    Ruco, L.5    Lampugnani, M.G.6    Dejana, E.7
  • 7
    • 0034807581 scopus 로고    scopus 로고
    • Cytoskeletal regulation of pulmonary vascular permeability
    • Dudek SM, Garcia JG. Cytoskeletal regulation of pulmonary vascular permeability. J Appl Physiol 91: 1487-1500, 2001.
    • (2001) J Appl Physiol , vol.91 , pp. 1487-1500
    • Dudek, S.M.1    Garcia, J.G.2
  • 8
    • 0037229213 scopus 로고    scopus 로고
    • Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters
    • Edaravone Acute Infarction Study Group
    • Edaravone Acute Infarction Study Group. Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. Cerebrovasc Dis 15: 222-229, 2003.
    • (2003) Cerebrovasc Dis , vol.15 , pp. 222-229
  • 9
    • 0035895735 scopus 로고    scopus 로고
    • Platelet-released phospholipids link haemostasis and angiogenesis
    • English D, Garcia JG, Brindley DN. Platelet-released phospholipids link haemostasis and angiogenesis. Cardiovasc Res 49: 588-599, 2001.
    • (2001) Cardiovasc Res , vol.49 , pp. 588-599
    • English, D.1    Garcia, J.G.2    Brindley, D.N.3
  • 10
    • 17044427680 scopus 로고    scopus 로고
    • Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation
    • Feistritzer C, Riewald M. Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation. Blood 105: 3178-3184, 2005.
    • (2005) Blood , vol.105 , pp. 3178-3184
    • Feistritzer, C.1    Riewald, M.2
  • 11
    • 20444443508 scopus 로고    scopus 로고
    • Activated protein C mediates novel lung endothelial barrier enhancement: Role of sphingosine 1-phosphate receptor transactivation
    • Finigan JH, Dudek SM, Singleton PA, Chiang ET, Jacobson JR, Camp SM, Ye SQ, Garcia JG. Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation. J Biol Chem 280: 17286-17293, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 17286-17293
    • Finigan, J.H.1    Dudek, S.M.2    Singleton, P.A.3    Chiang, E.T.4    Jacobson, J.R.5    Camp, S.M.6    Ye, S.Q.7    Garcia, J.G.8
  • 13
    • 0035516140 scopus 로고    scopus 로고
    • Transmembrane crosstalk between the extracellular matrix-cytoskeleton crosstalk
    • Geiger B, Bershadsky A, Pankov R, Yamada KM. Transmembrane crosstalk between the extracellular matrix-cytoskeleton crosstalk. Nat Rev Mol Cell Biol 2: 793-805, 2001.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 793-805
    • Geiger, B.1    Bershadsky, A.2    Pankov, R.3    Yamada, K.M.4
  • 14
    • 0031729124 scopus 로고    scopus 로고
    • Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate
    • Goetzl EJ, An S. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J 12: 1589-1598, 1998.
    • (1998) FASEB J , vol.12 , pp. 1589-1598
    • Goetzl, E.J.1    An, S.2
  • 16
  • 17
    • 0033564744 scopus 로고    scopus 로고
    • Induction and suppression of endothelial cell apoptosis by sphingolipids: A possible in vitro model for cell-cell interactions between platelets and endothelial cells
    • Hisano N, Yatomi Y, Satoh K, Akimoto S, Mitsumata M, Fujino MA, Ozaki Y. Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cells. Blood 93: 4293-4299, 1999.
    • (1999) Blood , vol.93 , pp. 4293-4299
    • Hisano, N.1    Yatomi, Y.2    Satoh, K.3    Akimoto, S.4    Mitsumata, M.5    Fujino, M.A.6    Ozaki, Y.7
  • 18
    • 0035853775 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. Differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells
    • Igarashi J, Bernier SG, Michel T. Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. Differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells. J Biol Chem 276: 12420-12426, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 12420-12426
    • Igarashi, J.1    Bernier, S.G.2    Michel, T.3
  • 19
    • 2142851264 scopus 로고    scopus 로고
    • Lysophospholipid receptors: Signaling and biology
    • Ishii I, Fukushima N, Ye X, Chun J. Lysophospholipid receptors: signaling and biology. Annu Rev Biochem 73: 321-354, 2004.
    • (2004) Annu Rev Biochem , vol.73 , pp. 321-354
    • Ishii, I.1    Fukushima, N.2    Ye, X.3    Chun, J.4
  • 20
    • 11344260687 scopus 로고    scopus 로고
    • Edaravone protects against lung injury induced by intestinal ischemia/reperfusion in rat
    • Ito K, Ozasa H, Horikawa S. Edaravone protects against lung injury induced by intestinal ischemia/reperfusion in rat. Free Radic Biol Med 38: 369-374, 2005.
    • (2005) Free Radic Biol Med , vol.38 , pp. 369-374
    • Ito, K.1    Ozasa, H.2    Horikawa, S.3
  • 22
    • 0032859045 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases
    • Kaibuchi K, Kuroda S, Fukata M, Nakagawa M. Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases. Curr Opin Cell Biol 11: 591-596, 1999.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 591-596
    • Kaibuchi, K.1    Kuroda, S.2    Fukata, M.3    Nakagawa, M.4
  • 27
    • 16644394172 scopus 로고    scopus 로고
    • Endothelial cell barrier regulation by sphingosine 1-phosphate
    • McVerry BJ, Garcia JG. Endothelial cell barrier regulation by sphingosine 1-phosphate. J Cell Biochem 92: 1075-1085, 2004.
    • (2004) J Cell Biochem , vol.92 , pp. 1075-1085
    • McVerry, B.J.1    Garcia, J.G.2
  • 28
    • 5644287793 scopus 로고    scopus 로고
    • In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: Mechanistic insights
    • McVerry BJ, Garcia JG. In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights. Cell Signal 17: 131-139, 2005.
    • (2005) Cell Signal , vol.17 , pp. 131-139
    • McVerry, B.J.1    Garcia, J.G.2
  • 29
    • 0037088851 scopus 로고    scopus 로고
    • Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function
    • Mehta D, Tiruppathi C, Sandoval R, Minshall RD, Holinstat M, Malik AB. Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function. J Physiol 539: 779-789, 2002.
    • (2002) J Physiol , vol.539 , pp. 779-789
    • Mehta, D.1    Tiruppathi, C.2    Sandoval, R.3    Minshall, R.D.4    Holinstat, M.5    Malik, A.B.6
  • 30
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Metha D, Malik AB. Signaling mechanisms regulating endothelial permeability. Physiol Rev 86: 279-367, 2006.
    • (2006) Physiol Rev , vol.86 , pp. 279-367
    • Metha, D.1    Malik, A.B.2
  • 31
    • 0034659907 scopus 로고    scopus 로고
    • Quantitative measurement of sphingosine 1-phosphate by radioreceptor-binding assay
    • Murata N, Sato K, Kon J, Tomura H, Okajima F. Quantitative measurement of sphingosine 1-phosphate by radioreceptor-binding assay. Anal Biochem 282: 15-120, 2000.
    • (2000) Anal Biochem , vol.282 , pp. 15-120
    • Murata, N.1    Sato, K.2    Kon, J.3    Tomura, H.4    Okajima, F.5
  • 32
    • 0025684851 scopus 로고
    • The control of vascular endothelial cell injury
    • Murota S, Morita I, Suda N. The control of vascular endothelial cell injury. Ann NY Acad Sci 598: 182-187, 1990.
    • (1990) Ann NY Acad Sci , vol.598 , pp. 182-187
    • Murota, S.1    Morita, I.2    Suda, N.3
  • 33
    • 0037162066 scopus 로고    scopus 로고
    • Differential effects of sphingosine 1-phosphate and lysophosphatidic acid on endothelial cells
    • Panetti TS. Differential effects of sphingosine 1-phosphate and lysophosphatidic acid on endothelial cells. Biochim Biophys Acta 1582: 190-196, 2002.
    • (2002) Biochim Biophys Acta , vol.1582 , pp. 190-196
    • Panetti, T.S.1
  • 34
    • 0038338507 scopus 로고    scopus 로고
    • Leucine-zipper-mediated homo- and hetero-dimerization of GIT family p95-ARF GTPase-activating protein, PIX-, paxillin-interacting proteins 1 and 2
    • Paris S, Longhi R, Santambrogio P, de Curtis I. Leucine-zipper-mediated homo- and hetero-dimerization of GIT family p95-ARF GTPase-activating protein, PIX-, paxillin-interacting proteins 1 and 2. Biochem J 372: 391-398, 2003.
    • (2003) Biochem J , vol.372 , pp. 391-398
    • Paris, S.1    Longhi, R.2    Santambrogio, P.3    de Curtis, I.4
  • 35
    • 0142169969 scopus 로고    scopus 로고
    • Antioxidant MCI-186 inhibits mitochondrial permeability transition pore and upregulates Bcl-2 expression
    • Rajesh KG, Sasaguri S, Suzuki R, Maeda H. Antioxidant MCI-186 inhibits mitochondrial permeability transition pore and upregulates Bcl-2 expression. Am J Physiol Heart Circ Physiol 285: H2171-H2178, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Rajesh, K.G.1    Sasaguri, S.2    Suzuki, R.3    Maeda, H.4
  • 36
    • 0035196711 scopus 로고    scopus 로고
    • EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration
    • Rosenfeldt HM, Hobson JP, Maceyka M, Olivera A, Nava VE, Milstien S, Spiegel S. EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration. FASEB J 15: 2649-2659, 2001.
    • (2001) FASEB J , vol.15 , pp. 2649-2659
    • Rosenfeldt, H.M.1    Hobson, J.P.2    Maceyka, M.3    Olivera, A.4    Nava, V.E.5    Milstien, S.6    Spiegel, S.7
  • 37
    • 34249280944 scopus 로고    scopus 로고
    • Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN
    • Sanchez T, Skoura A, Wu MT, Casserly B, Harrington EO, Hia T. Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. Arterioscler Thromb Vasc Biol 27: 1312-1318, 2007.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1312-1318
    • Sanchez, T.1    Skoura, A.2    Wu, M.T.3    Casserly, B.4    Harrington, E.O.5    Hia, T.6
  • 40
    • 0035948579 scopus 로고    scopus 로고
    • Biochemical signals and biological responses elicited by the focal adhesion kinase
    • Schaller MD. Biochemical signals and biological responses elicited by the focal adhesion kinase. Biochim Biophys Acta 1540: 1-21, 2001.
    • (2001) Biochim Biophys Acta , vol.1540 , pp. 1-21
    • Schaller, M.D.1
  • 41
    • 0035344650 scopus 로고    scopus 로고
    • Cell control by membrane-cytoskeleton adhesion
    • Sheetz MP. Cell control by membrane-cytoskeleton adhesion. Nat Rev Mol Cell Biol 2: 392-396, 2001.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 392-396
    • Sheetz, M.P.1
  • 42
    • 0037370946 scopus 로고    scopus 로고
    • S1P induces FA remodeling in human pulmonary endothelial cells: Role of Rac, GIT1, FAK and paxillin
    • Shikata Y, Birukov KG, Garcia JG. S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK and paxillin. J Appl Physiol 94: 1193-1203, 2003a.
    • (2003) J Appl Physiol , vol.94 , pp. 1193-1203
    • Shikata, Y.1    Birukov, K.G.2    Garcia, J.G.3
  • 43
    • 0345529916 scopus 로고    scopus 로고
    • Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate-and thrombin-induced focal adhesion remodeling: Role of Src and GIT
    • Shikata Y, Birukov KG, Birukova AA, Verin A, Garcia JG. Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate-and thrombin-induced focal adhesion remodeling: role of Src and GIT. FASEB J 17: 2240-2249, 2003b.
    • (2003) FASEB J , vol.17 , pp. 2240-2249
    • Shikata, Y.1    Birukov, K.G.2    Birukova, A.A.3    Verin, A.4    Garcia, J.G.5
  • 44
    • 13544264582 scopus 로고    scopus 로고
    • Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells
    • Shikata Y, Rios A, Kawkitinarong K, DePaola N, Garcia JG, Birukov KG. Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells. Exp Cell Res 304: 40-49, 2005.
    • (2005) Exp Cell Res , vol.304 , pp. 40-49
    • Shikata, Y.1    Rios, A.2    Kawkitinarong, K.3    DePaola, N.4    Garcia, J.G.5    Birukov, K.G.6
  • 45
    • 26444551684 scopus 로고    scopus 로고
    • Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin
    • Singleton PA, Dudek SM, Chiang ET, Garcia JG. Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin. FASEB J 19: 1646-1656, 2005.
    • (2005) FASEB J , vol.19 , pp. 1646-1656
    • Singleton, P.A.1    Dudek, S.M.2    Chiang, E.T.3    Garcia, J.G.4
  • 47
    • 0037044854 scopus 로고    scopus 로고
    • Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitricoxide synthase (eNOS)
    • Tanimoto T, Jin ZG, Berk BC. Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitricoxide synthase (eNOS). J Biol Chem 277: 42997-43001, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 42997-43001
    • Tanimoto, T.1    Jin, Z.G.2    Berk, B.C.3
  • 48
    • 2342587454 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate transactivates the platelet-derived growth factor β receptor and epidermal growth factor receptor in vascular smooth muscle cells
    • Tanimoto T, Lungu AO, Berk BC. Sphingosine 1-phosphate transactivates the platelet-derived growth factor β receptor and epidermal growth factor receptor in vascular smooth muscle cells. Circ Res 94: 1050-1058, 2004.
    • (2004) Circ Res , vol.94 , pp. 1050-1058
    • Tanimoto, T.1    Lungu, A.O.2    Berk, B.C.3
  • 50
  • 53
    • 0037096160 scopus 로고    scopus 로고
    • Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells
    • Vouret-Craviari V, Bourcier C, Boulter E, van Obberghen-Schilling E. Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells. J Cell Sci 115: 2475-2484, 2002.
    • (2002) J Cell Sci , vol.115 , pp. 2475-2484
    • Vouret-Craviari, V.1    Bourcier, C.2    Boulter, E.3    van Obberghen-Schilling, E.4
  • 55
    • 0035338471 scopus 로고    scopus 로고
    • Integrin binding to fibronectin and vitronectin maintains the barrier function of isolated porcine coronary venules
    • Wu MH, Ustinova E, Granger HJ. Integrin binding to fibronectin and vitronectin maintains the barrier function of isolated porcine coronary venules. J Physiol 532: 785-791, 2001.
    • (2001) J Physiol , vol.532 , pp. 785-791
    • Wu, M.H.1    Ustinova, E.2    Granger, H.J.3
  • 56
    • 0029128576 scopus 로고
    • Quantitative measurement of sphingosine 1-phosphate in biological samples by acylation with radioactive acetic anhydride
    • Yatomi Y, Ruan F, Ohta J, Welch RJ, Hakomori S, Igarashi Y. Quantitative measurement of sphingosine 1-phosphate in biological samples by acylation with radioactive acetic anhydride. Anal Biochem 230: 315-320, 1995.
    • (1995) Anal Biochem , vol.230 , pp. 315-320
    • Yatomi, Y.1    Ruan, F.2    Ohta, J.3    Welch, R.J.4    Hakomori, S.5    Igarashi, Y.6
  • 57
    • 13844275484 scopus 로고    scopus 로고
    • Yoshida H, Sasaki K, Namiki Y, Sato N, Tada N. Edaravone, a novel radical scavenger, inhibits oxidative modification of low-density lipoprotein (LDL) and reverses oxidized LDL-mediated reduction in the expression of endothelial nitric oxide synthase. Atherosclerosis 179: 97-102, 2005.
    • Yoshida H, Sasaki K, Namiki Y, Sato N, Tada N. Edaravone, a novel radical scavenger, inhibits oxidative modification of low-density lipoprotein (LDL) and reverses oxidized LDL-mediated reduction in the expression of endothelial nitric oxide synthase. Atherosclerosis 179: 97-102, 2005.
  • 58
    • 0042344708 scopus 로고    scopus 로고
    • Protein kinase signaling in the modulation of microvascular permeability
    • Yuan SY. Protein kinase signaling in the modulation of microvascular permeability. Vasc Pharmacol 39: 213-223, 2002.
    • (2002) Vasc Pharmacol , vol.39 , pp. 213-223
    • Yuan, S.Y.1
  • 59
    • 0142231502 scopus 로고    scopus 로고
    • Normalization by edaravone, a free radical scavenger, of irradiation-reduced endothelial nitric oxide synthase expression
    • Zhang XH, Matsuda N, Jesmin S, Sakuraya F, Gando S, Kemmotsu O, Hattori Y. Normalization by edaravone, a free radical scavenger, of irradiation-reduced endothelial nitric oxide synthase expression. Eur J Pharmacol 476: 131-137, 2003.
    • (2003) Eur J Pharmacol , vol.476 , pp. 131-137
    • Zhang, X.H.1    Matsuda, N.2    Jesmin, S.3    Sakuraya, F.4    Gando, S.5    Kemmotsu, O.6    Hattori, Y.7


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