PPARα agonists positively and negatively regulate the expression of several nutrient/drug transporters in mouse small intestine

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 11, 2007, Pages 2185-2190

  Hirai, Toshitake ^a   Fukui, Yuka ^a   Motojima, Kiyoto ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Drug drug interaction; GW7647; Microarray; Peroxisome proliferator activated receptor; Small intestine; Transporter

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; MESSENGER RNA; PEPTIDE TRANSPORTER 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PROTEIN DERIVATIVE; PROTEIN SLC22A5; UNCLASSIFIED DRUG; ABC TRANSPORTER; ABCD3 PROTEIN, MOUSE; BCRP PROTEIN, MOUSE; COTRANSPORTER; FATP2 PROTEIN, MOUSE; LONG CHAIN FATTY ACID COENZYME A LIGASE; MCT13 PROTEIN, MOUSE; MEMBRANE PROTEIN; MONOCARBOXYLATE TRANSPORTER; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; ORGANIC ANION TRANSPORTER; ORGANIC CATION TRANSPORTER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SLC22A5 PROTEIN, MOUSE; SODIUM DEPENDENT VITAMIN C TRANSPORTER 2; SODIUM-DEPENDENT VITAMIN C TRANSPORTER 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUTRIENT; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; SMALL INTESTINE; ANIMAL; C57BL MOUSE; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; COENZYME A LIGASES; GENE EXPRESSION REGULATION; INTESTINE, SMALL; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MONOCARBOXYLIC ACID TRANSPORTERS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; ORGANIC CATION TRANSPORT PROTEINS; PPAR ALPHA; SYMPORTERS;

EID: 36048940510     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.2185     Document Type: Article

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