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Volumn 67, Issue 21, 2007, Pages 10099-10102

Keeping out the bad guys: Gateway to cellular target therapy

Author keywords

[No Author keywords available]

Indexed keywords

1 [5 CHLORO 2 [2 [4 (4 FLUOROBENZYL) 2 METHYL 1 PIPERAZINYL] 2 OXOETHOXY]PHENYL]UREA; CHEMOKINE; CHEMOKINE CCL9; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR1 ANTAGONIST; MATRIX METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 35948951564     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-2100     Document Type: Review
Times cited : (36)

References (33)
  • 3
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004;432:332-7.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 5
    • 0034721666 scopus 로고    scopus 로고
    • MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
    • Coussens LM, Tinkle CL, Hanahan D, Werb Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 2000;103:481-90.
    • (2000) Cell , vol.103 , pp. 481-490
    • Coussens, L.M.1    Tinkle, C.L.2    Hanahan, D.3    Werb, Z.4
  • 6
    • 0033215242 scopus 로고    scopus 로고
    • Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
    • Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999;59:5002-11.
    • (1999) Cancer Res , vol.59 , pp. 5002-5011
    • Olumi, A.F.1    Grossfeld, G.D.2    Hayward, S.W.3    Carroll, P.R.4    Tlsty, T.D.5    Cunha, G.R.6
  • 7
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: An organizing principle for drug discovery?
    • Folkman J. Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 2007;6:273-86.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 273-286
    • Folkman, J.1
  • 9
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005;121:335-48.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3
  • 10
    • 0035911221 scopus 로고    scopus 로고
    • Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin EY, Nguyen AV, Russel RG, Pollard JW. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 2001;193:727-39.
    • (2001) J Exp Med , vol.193 , pp. 727-739
    • Lin, E.Y.1    Nguyen, A.V.2    Russel, R.G.3    Pollard, J.W.4
  • 11
    • 0032489508 scopus 로고    scopus 로고
    • Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF, Taketo MM. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 1998;92:645-56.
    • Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF, Taketo MM. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 1998;92:645-56.
  • 12
    • 0038049137 scopus 로고    scopus 로고
    • Tumor-cell invasion and migration: Diversity and escape mechanisms
    • Friedl P, Wolf K. Tumor-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 2003;3:362-74.
    • (2003) Nat Rev Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 13
    • 34047138860 scopus 로고    scopus 로고
    • SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion
    • Kitamura T, Kometani K, Hashida H, et al. SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nat Genet 2007;39:467-75.
    • (2007) Nat Genet , vol.39 , pp. 467-475
    • Kitamura, T.1    Kometani, K.2    Hashida, H.3
  • 14
    • 34249280238 scopus 로고    scopus 로고
    • Moving out: Invasion and metastasis. The biology of cancer
    • Chapter 14, New York, NY
    • Weinberg RA. Moving out: invasion and metastasis. The biology of cancer. Chapter 14. New York: Garland Science, Taylor & Francis Group, LLC; New York, NY. 2007. p. 587-654.
    • (2007) New York: Garland Science, Taylor & Francis Group, LLC , pp. 587-654
    • Weinberg, R.A.1
  • 15
    • 24944587964 scopus 로고    scopus 로고
    • Tie2identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
    • De Palma M, Venneri MA. Galli R, et al. Tie2identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell 2005;8:211-226.
    • (2005) Cancer Cell , vol.8 , pp. 211-226
    • De Palma, M.1    Venneri, M.A.2    Galli, R.3
  • 16
    • 5444225991 scopus 로고    scopus 로고
    • + cells in tumor-bearing host directly promotes tumor angiogenesis
    • + cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 2004;6:409-421.
    • (2004) Cancer Cell , vol.6 , pp. 409-421
    • Yang, L.1    DeBusk, L.M.2    Fukuda, K.3
  • 17
    • 26944437515 scopus 로고    scopus 로고
    • + perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival
    • + perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival. Nat Cell Biol 2005;7:870-9.
    • (2005) Nat Cell Biol , vol.7 , pp. 870-879
    • Song, S.1    Ewald, A.J.2    Stallcup, W.3    Werb, Z.4    Bergers, G.5
  • 18
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
    • Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005;438:820-7.
    • (2005) Nature , vol.438 , pp. 820-827
    • Kaplan, R.N.1    Riba, R.D.2    Zacharoulis, S.3
  • 19
    • 4944229701 scopus 로고    scopus 로고
    • A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
    • Wyckoff J, Wang W, Lin EY, et al. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res 2004;64:7022-9.
    • (2004) Cancer Res , vol.64 , pp. 7022-7029
    • Wyckoff, J.1    Wang, W.2    Lin, E.Y.3
  • 20
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F. Cancer and the chemokine network. Nat Rev Cancer 2004;4:540-50.
    • (2004) Nat Rev Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 21
    • 2542612840 scopus 로고    scopus 로고
    • Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes
    • Kawada K, Sonoshita M, Sakashita H, et al. Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes. Cancer Res 2004;64:4010-7.
    • (2004) Cancer Res , vol.64 , pp. 4010-4017
    • Kawada, K.1    Sonoshita, M.2    Sakashita, H.3
  • 22
    • 34447524931 scopus 로고    scopus 로고
    • Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes
    • Kawada K, Hosogi H, Sonoshita M, et al. Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes. Oncogene 2007;26:4679-88.
    • (2007) Oncogene , vol.26 , pp. 4679-4688
    • Kawada, K.1    Hosogi, H.2    Sonoshita, M.3
  • 23
    • 2342587509 scopus 로고    scopus 로고
    • Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice
    • Oshima H, Oshima M, Inaba K, Taketo MM. Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice. EMBO J 2004;23:1669-78.
    • (2004) EMBO J , vol.23 , pp. 1669-1678
    • Oshima, H.1    Oshima, M.2    Inaba, K.3    Taketo, M.M.4
  • 24
    • 23844544931 scopus 로고    scopus 로고
    • BX471: A CCR1 antagonist with antiinflammatory activity in man
    • Horuk R. BX471: a CCR1 antagonist with antiinflammatory activity in man. Mini Rev Med Chem 2005;5:791-804.
    • (2005) Mini Rev Med Chem , vol.5 , pp. 791-804
    • Horuk, R.1
  • 25
    • 0034705618 scopus 로고    scopus 로고
    • Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1
    • Liang M, Mallari C, Rosser M, et al. Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. J Biol Chem 2000;275:19000-8.
    • (2000) J Biol Chem , vol.275 , pp. 19000-19008
    • Liang, M.1    Mallari, C.2    Rosser, M.3
  • 26
    • 0035830871 scopus 로고    scopus 로고
    • A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection
    • Horuk H, Clayberger C, Krensky AM, et al. A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection. J Biol Chem 2001;276:4199-204.
    • (2001) J Biol Chem , vol.276 , pp. 4199-4204
    • Horuk, H.1    Clayberger, C.2    Krensky, A.M.3
  • 27
    • 9944258056 scopus 로고    scopus 로고
    • The role of gelatinases in colorectal cancer progression and metastasis
    • Mook ORF, Frederiks WM, Van Noorden CJF. The role of gelatinases in colorectal cancer progression and metastasis. Biochim Biophys Acta 2004;1705:69-89.
    • (2004) Biochim Biophys Acta , vol.1705 , pp. 69-89
    • Mook, O.R.F.1    Frederiks, W.M.2    Van Noorden, C.J.F.3
  • 28
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 2002;295:2387-92.
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 29
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002;2:161-74.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 30
    • 33644545381 scopus 로고    scopus 로고
    • Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
    • Overall CM, Kleifeld O. Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat Rev Cancer 2006;6:227-39.
    • (2006) Nat Rev Cancer , vol.6 , pp. 227-239
    • Overall, C.M.1    Kleifeld, O.2
  • 31
    • 33846643454 scopus 로고    scopus 로고
    • Cysteine cathepsins and the cutting edge of cancer invasion
    • Gocheva V, Joyce JA. Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle 2007;6:60-4.
    • (2007) Cell Cycle , vol.6 , pp. 60-64
    • Gocheva, V.1    Joyce, J.A.2
  • 32
    • 22344436842 scopus 로고    scopus 로고
    • Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy
    • Curino AC, Engelholm LH, Yamada SS, et al. Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy. J Cell Biol 2005;169:977-85.
    • (2005) J Cell Biol , vol.169 , pp. 977-985
    • Curino, A.C.1    Engelholm, L.H.2    Yamada, S.S.3
  • 33
    • 0030913175 scopus 로고    scopus 로고
    • Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2cy tokine balance in mice lacking CC chemokine receptor 1
    • Gao J-L, Wynn TA, Chang Y, et al. Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2cy tokine balance in mice lacking CC chemokine receptor 1. J Exp Med 1997;185:1959-68.
    • (1997) J Exp Med , vol.185 , pp. 1959-1968
    • Gao, J.-L.1    Wynn, T.A.2    Chang, Y.3


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