A Non-peptide Functional Antagonist of the CCR1 Chemokine Receptor Is Effective in Rat Heart Transplant Rejection

Journal of Biological Chemistry

Volumn 276, Issue 6, 2001, Pages 4199-4204

  Horuk, Richard ^a   Clayberger, Carol ^c   Krensky, Alan M ^d   Wang, Zhaohui ^c   Gröne, Hermann Josef ^d   Weber, Christian ^e   Weber, Kim S C ^e   Nelson, Peter J ^e   May, Karen ^b   Rosser, Mary ^b   Dunning, Laura ^b   Liang, Meina ^b   Buckman, Brad ^b   Ghannam, Ameen ^b   Ng, Howard P ^b   Islam, Imadul ^b   Bauman, John G ^b   Wei, Guo Ping ^b   Monahan, Sean ^b   Xu, Wei ^b   Snider, R Michael ^b   Morrissey, Michael M ^b   Hesselgesser, Joseph ^a   Perez, H Daniel ^a   more..

^a BAYER AG   (Germany)

^b Discovery Research Group   (United States)

^c STANFORD UNIVERSITY   (United States)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; BIOASSAY; TRANSPLANTATION (SURGICAL);

CHEMOKINES;

BIOCHEMISTRY;

1 [5 CHLORO 2 [2 [4 (4 FLUOROBENZYL) 2 METHYL 1 PIPERAZINYL] 2 OXOETHOXY]PHENYL]UREA; CHEMOKINE RECEPTOR CCR1; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; RANTES; UNCLASSIFIED DRUG; CARBANILAMIDE DERIVATIVE; CC CHEMOKINE RECEPTOR 1; CHEMOKINE RECEPTOR; PIPERIDINE DERIVATIVE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM; GRAFT REJECTION; HEART GRAFT; HETEROTOPIC TRANSPLANTATION; HISTOPATHOLOGY; IN VITRO STUDY; MALE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CELL LINE; DRUG ANTAGONISM; GRAFT SURVIVAL; HEART TRANSPLANTATION; HUMAN; LEWIS RAT; PHYSIOLOGY;

ANIMALIA;

ANIMALS; CELL LINE; CYCLOSPORINE; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HUMANS; MALE; PHENYLUREA COMPOUNDS; PIPERIDINES; RATS; RATS, INBRED LEW; RECEPTORS, CHEMOKINE;

EID: 0035830871     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007457200     Document Type: Article

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