-
1
-
-
0028144758
-
Close similarity of baculovirus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors
-
Areces LB, Kazanietz MG, Blumberg PM. Close similarity of baculovirus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors. J Biol Chem 1994; 269:19553-8.
-
(1994)
J Biol Chem
, vol.269
, pp. 19553-19558
-
-
Areces, L.B.1
Kazanietz, M.G.2
Blumberg, P.M.3
-
2
-
-
0030611884
-
Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters
-
Caloca MJ, Fernandez N, Lewin NE, Ching D, Modali R, Blumberg PM, Kazanietz MG. Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters. J Biol Chem 1997; 272:26488-96.
-
(1997)
J Biol Chem
, vol.272
, pp. 26488-26496
-
-
Caloca, M.J.1
Fernandez, N.2
Lewin, N.E.3
Ching, D.4
Modali, R.5
Blumberg, P.M.6
Kazanietz, M.G.7
-
3
-
-
0027282112
-
Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n- chimerin gene, is selectively expressed in brain regions and testes
-
Hall C, Sin WC, Teo M, Michael GJ, Smith P, Dong JM, Lim HH, Manser E, Spurr NK, Jones TA, et al. Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n- chimerin gene, is selectively expressed in brain regions and testes. Mol Cell Biol 1993; 13:4986-98.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4986-4998
-
-
Hall, C.1
Sin, W.C.2
Teo, M.3
Michael, G.J.4
Smith, P.5
Dong, J.M.6
Lim, H.H.7
Manser, E.8
Spurr, N.K.9
Jones, T.A.10
-
4
-
-
0028180706
-
Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21 ras- related rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain
-
Leung T, How BE, Manser E, Lim L. Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21 ras- related rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain. J Biol Chem 1994; 269:12888-92.
-
(1994)
J Biol Chem
, vol.269
, pp. 12888-12892
-
-
Leung, T.1
How, B.E.2
Manser, E.3
Lim, L.4
-
5
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature 2002; 420:629-35.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
7
-
-
0035913909
-
Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway
-
Billuart P, Winter CG, Maresh A, Zhao X, Luo L. Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway. Cell 2001; 107:195-207.
-
(2001)
Cell
, vol.107
, pp. 195-207
-
-
Billuart, P.1
Winter, C.G.2
Maresh, A.3
Zhao, X.4
Luo, L.5
-
8
-
-
2342418629
-
-
Wennerberg K, Der CJ. Rho-family GTPases: It's not only Rac and Rho (and I like it). J Cell Sci 2004; 117:1301-12.
-
Wennerberg K, Der CJ. Rho-family GTPases: It's not only Rac and Rho (and I like it). J Cell Sci 2004; 117:1301-12.
-
-
-
-
9
-
-
33747293858
-
Rho GTPase activating proteins in cancer phenotypes
-
Kandpal RP. Rho GTPase activating proteins in cancer phenotypes. Curr Protein Pept Sci 2006; 7:355-65.
-
(2006)
Curr Protein Pept Sci
, vol.7
, pp. 355-365
-
-
Kandpal, R.P.1
-
11
-
-
0029133178
-
Identification and characterization of human beta 2-chimaerin: Association with malignant transformation in astrocytoma
-
Yuan S, Miller DW, Barnett GH, Hahn JF, Williams BR. Identification and characterization of human beta 2-chimaerin: Association with malignant transformation in astrocytoma. Cancer Res 1995; 55:3456-61.
-
(1995)
Cancer Res
, vol.55
, pp. 3456-3461
-
-
Yuan, S.1
Miller, D.W.2
Barnett, G.H.3
Hahn, J.F.4
Williams, B.R.5
-
12
-
-
0038375063
-
Inhibition of aggressiveness of metastatic mouse mammary carcinoma cells by the beta2-chimaerin GAP domain
-
Menna PL, Skilton G, Leskow FC, Alonso DF, Gomez DE, Kazanietz MG. Inhibition of aggressiveness of metastatic mouse mammary carcinoma cells by the beta2-chimaerin GAP domain. Cancer Res 2003; 63:2284-91.
-
(2003)
Cancer Res
, vol.63
, pp. 2284-2291
-
-
Menna, P.L.1
Skilton, G.2
Leskow, F.C.3
Alonso, D.F.4
Gomez, D.E.5
Kazanietz, M.G.6
-
13
-
-
33645784615
-
The zebrafish homologue of mammalian chimerin Rac-GAPs is implicated in epiboly progression during development
-
Leskow FC, Holloway BA, Wang H, Mullins MC, Kazanietz MG. The zebrafish homologue of mammalian chimerin Rac-GAPs is implicated in epiboly progression during development. Proc Natl Acad Sci USA 2006; 103:5373-8.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5373-5378
-
-
Leskow, F.C.1
Holloway, B.A.2
Wang, H.3
Mullins, M.C.4
Kazanietz, M.G.5
-
14
-
-
34249854727
-
Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye
-
Bruinsma SP, Cagan RL, Baranski TJ. Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye. Proc Natl Acad Sci USA 2007; 104:7098-103.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7098-7103
-
-
Bruinsma, S.P.1
Cagan, R.L.2
Baranski, T.J.3
-
15
-
-
23144434969
-
Using Drosophila melanogaster to map human cancer pathways
-
Brumby AM, Richardson HE. Using Drosophila melanogaster to map human cancer pathways. Nat Rev Cancer 2005; 5:626-39.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 626-639
-
-
Brumby, A.M.1
Richardson, H.E.2
-
16
-
-
30644469503
-
Drosophila models for cancer research
-
Vidal M, Cagan RL. Drosophila models for cancer research. Curr Opin Genet Dev 2006; 16:10-6.
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 10-16
-
-
Vidal, M.1
Cagan, R.L.2
-
17
-
-
29744462234
-
Csk-deficient boundary cells are eliminated from normal Drosophila epithelia by exclusion, migration, and apoptosis
-
Vidal M, Larson DE, Cagan RL. Csk-deficient boundary cells are eliminated from normal Drosophila epithelia by exclusion, migration, and apoptosis. Dev Cell 2006; 10:33-44.
-
(2006)
Dev Cell
, vol.10
, pp. 33-44
-
-
Vidal, M.1
Larson, D.E.2
Cagan, R.L.3
-
18
-
-
18144392678
-
ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma
-
Vidal M, Wells S, Ryan A, Cagan R. ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma. Cancer Res 2005; 65:3538-41.
-
(2005)
Cancer Res
, vol.65
, pp. 3538-3541
-
-
Vidal, M.1
Wells, S.2
Ryan, A.3
Cagan, R.4
-
19
-
-
0035921928
-
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines
-
Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK. Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines. Nature 2001; 413:311-6.
-
(2001)
Nature
, vol.413
, pp. 311-316
-
-
Moberg, K.H.1
Bell, D.W.2
Wahrer, D.C.3
Haber, D.A.4
Hariharan, I.K.5
-
20
-
-
0142137116
-
Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response
-
Jassim OW, Fink JL, Cagan RL. Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response. Embo J 2003; 22:5622-32.
-
(2003)
Embo J
, vol.22
, pp. 5622-5632
-
-
Jassim, O.W.1
Fink, J.L.2
Cagan, R.L.3
-
21
-
-
33846064113
-
-
Barrett T, Troup DB, Wilhite SE, Ledoux P, Rudnev D, Evangelista C, Kim IF, Soboleva A, Tomashevsky M, Edgar R. NCBI GEO: Mining tens of millions of expression profiles-database and tools update. Nucleic Acids Res 2007; 35:D760-5.
-
Barrett T, Troup DB, Wilhite SE, Ledoux P, Rudnev D, Evangelista C, Kim IF, Soboleva A, Tomashevsky M, Edgar R. NCBI GEO: Mining tens of millions of expression profiles-database and tools update. Nucleic Acids Res 2007; 35:D760-5.
-
-
-
-
23
-
-
19944432938
-
Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis
-
Fernandez-Zapico ME, Gonzalez-Paz NC, Weiss E, Savoy DN, Molina JR, Fonseca R, Smyrk TC, Chari ST, Urrutia R, Billadeau DD. Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis. Cancer Cell 2005; 7:39-49.
-
(2005)
Cancer Cell
, vol.7
, pp. 39-49
-
-
Fernandez-Zapico, M.E.1
Gonzalez-Paz, N.C.2
Weiss, E.3
Savoy, D.N.4
Molina, J.R.5
Fonseca, R.6
Smyrk, T.C.7
Chari, S.T.8
Urrutia, R.9
Billadeau, D.D.10
-
24
-
-
0033578005
-
G-protein-coupled receptor heterodimerization modulates receptor function
-
Jordan BA, Devi LA. G-protein-coupled receptor heterodimerization modulates receptor function. Nature 1999; 399:697-700.
-
(1999)
Nature
, vol.399
, pp. 697-700
-
-
Jordan, B.A.1
Devi, L.A.2
-
25
-
-
0038556694
-
Tumor progression: Small GTPases and loss of cell-cell adhesion
-
Lozano E, Betson M, Braga VM. Tumor progression: Small GTPases and loss of cell-cell adhesion. Bioessays 2003; 25:452-63.
-
(2003)
Bioessays
, vol.25
, pp. 452-463
-
-
Lozano, E.1
Betson, M.2
Braga, V.M.3
-
27
-
-
33646788066
-
Phospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signaling
-
Wang H, Yang C, Leskow FC, Sun J, Canagarajah B, Hurley JH, Kazanietz MG. Phospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signaling. Embo J 2006; 25:2062-74.
-
(2006)
Embo J
, vol.25
, pp. 2062-2074
-
-
Wang, H.1
Yang, C.2
Leskow, F.C.3
Sun, J.4
Canagarajah, B.5
Hurley, J.H.6
Kazanietz, M.G.7
-
28
-
-
33846444740
-
Diacylglycerol kinase gamma interacts with and activates beta2-chimaerin, a Rac-specific GAP, in response to epidermal growth factor
-
Yasuda S, Kai M, Imai S, Kanoh H, Sakane F. Diacylglycerol kinase gamma interacts with and activates beta2-chimaerin, a Rac-specific GAP, in response to epidermal growth factor. FEBS Lett 2007; 581:551-7.
-
(2007)
FEBS Lett
, vol.581
, pp. 551-557
-
-
Yasuda, S.1
Kai, M.2
Imai, S.3
Kanoh, H.4
Sakane, F.5
-
29
-
-
31344467784
-
Essential role for Rac in heregulin beta1 mitogenic signaling: A mechanism that involves epidermal growth factor receptor and is independent of ErbB4
-
Yang C, Liu Y, Lemmon MA, Kazanietz MG. Essential role for Rac in heregulin beta1 mitogenic signaling: A mechanism that involves epidermal growth factor receptor and is independent of ErbB4. Mol Cell Biol 2006; 26:831-42.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 831-842
-
-
Yang, C.1
Liu, Y.2
Lemmon, M.A.3
Kazanietz, M.G.4
-
30
-
-
23844494402
-
The duration, magnitude and compartmentalization of ERK MAP kinase activity: Mechanisms for providing signaling specificity
-
Ebisuya M, Kondoh K, Nishida E. The duration, magnitude and compartmentalization of ERK MAP kinase activity: Mechanisms for providing signaling specificity. J Cell Sci 2005; 118:2997-3002.
-
(2005)
J Cell Sci
, vol.118
, pp. 2997-3002
-
-
Ebisuya, M.1
Kondoh, K.2
Nishida, E.3
-
31
-
-
30944447568
-
The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
-
Yoon S, Seger R. The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions. Growth Factors 2006; 24:21-44.
-
(2006)
Growth Factors
, vol.24
, pp. 21-44
-
-
Yoon, S.1
Seger, R.2
-
32
-
-
0033081066
-
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
-
Brunet A, Roux D, Lenormand P, Dowd S, Keyse S, Pouyssegur J. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. Embo J 1999; 18:664-74.
-
(1999)
Embo J
, vol.18
, pp. 664-674
-
-
Brunet, A.1
Roux, D.2
Lenormand, P.3
Dowd, S.4
Keyse, S.5
Pouyssegur, J.6
-
33
-
-
31644444050
-
MAP kinase subcellular localization controls both pattern and proliferation in the developing Drosophila wing
-
Marenda DR, Vrailas AD, Rodrigues AB, Cook S, Powers MA, Lorenzen JA, Perkins LA, Moses K. MAP kinase subcellular localization controls both pattern and proliferation in the developing Drosophila wing. Development 2006; 133:43-51.
-
(2006)
Development
, vol.133
, pp. 43-51
-
-
Marenda, D.R.1
Vrailas, A.D.2
Rodrigues, A.B.3
Cook, S.4
Powers, M.A.5
Lorenzen, J.A.6
Perkins, L.A.7
Moses, K.8
-
34
-
-
33644506760
-
Scaffold proteins in MAP kinase signaling: More than simple passive activating platforms
-
Dard N, Peter M. Scaffold proteins in MAP kinase signaling: More than simple passive activating platforms. Bioessays 2006; 28:146-56.
-
(2006)
Bioessays
, vol.28
, pp. 146-156
-
-
Dard, N.1
Peter, M.2
-
35
-
-
27644575157
-
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
-
Kolch W. Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat Rev Mol Cell Biol 2005; 6:827-37.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 827-837
-
-
Kolch, W.1
-
36
-
-
0036899420
-
Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction
-
Teis D, Wunderlich W, Huber LA. Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction. Dev Cell 2002; 3:803-14.
-
(2002)
Dev Cell
, vol.3
, pp. 803-814
-
-
Teis, D.1
Wunderlich, W.2
Huber, L.A.3
-
37
-
-
4143070533
-
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
-
Ahn S, Shenoy SK, Wei H, Lefkowitz RJ. Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. J Biol Chem 2004; 279:35518-25.
-
(2004)
J Biol Chem
, vol.279
, pp. 35518-35525
-
-
Ahn, S.1
Shenoy, S.K.2
Wei, H.3
Lefkowitz, R.J.4
-
38
-
-
33847759815
-
PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2
-
Glading A, Koziol JA, Krueger J, Ginsberg MH. PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2. Cancer Res 2007; 67:1536-44.
-
(2007)
Cancer Res
, vol.67
, pp. 1536-1544
-
-
Glading, A.1
Koziol, J.A.2
Krueger, J.3
Ginsberg, M.H.4
-
39
-
-
0036774217
-
Cell-cell adhesion and signalling
-
Braga VM. Cell-cell adhesion and signalling. Curr Opin Cell Biol 2002; 14:546-56.
-
(2002)
Curr Opin Cell Biol
, vol.14
, pp. 546-556
-
-
Braga, V.M.1
-
40
-
-
1042267263
-
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
-
Cavallaro U, Christofori G. Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat Rev Cancer 2004; 4:118-32.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 118-132
-
-
Cavallaro, U.1
Christofori, G.2
-
41
-
-
0032510494
-
A causal role for E-cadherin in the transition from adenoma to carcinoma
-
Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 1998; 392:190-3.
-
(1998)
Nature
, vol.392
, pp. 190-193
-
-
Perl, A.K.1
Wilgenbus, P.2
Dahl, U.3
Semb, H.4
Christofori, G.5
-
42
-
-
0033730417
-
Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes
-
Braga VM, Betson M, Li X, Lamarche-Vane N. Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes. Mol Biol Cell 2000; 11:3703-21.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 3703-3721
-
-
Braga, V.M.1
Betson, M.2
Li, X.3
Lamarche-Vane, N.4
-
43
-
-
0037386182
-
Rac promotes epithelial cell rearrangement during tracheal tubulogenesis in Drosophila
-
Chihara T, Kato K, Taniguchi M, Ng J, Hayashi S. Rac promotes epithelial cell rearrangement during tracheal tubulogenesis in Drosophila. Development 2003; 130:1419-28.
-
(2003)
Development
, vol.130
, pp. 1419-1428
-
-
Chihara, T.1
Kato, K.2
Taniguchi, M.3
Ng, J.4
Hayashi, S.5
-
44
-
-
0037020084
-
Rac activation upon cell-cell contact formation is dependent on signaling from the epidermal growth factor receptor
-
Betson M, Lozano E, Zhang J, Braga VM. Rac activation upon cell-cell contact formation is dependent on signaling from the epidermal growth factor receptor. J Biol Chem 2002; 277:36962-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 36962-36969
-
-
Betson, M.1
Lozano, E.2
Zhang, J.3
Braga, V.M.4
-
45
-
-
0030718609
-
Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells
-
Takaishi K, Sasaki T, Kotani H, Nishioka H, Takai Y. Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J Cell Biol 1997; 139:1047-59.
-
(1997)
J Cell Biol
, vol.139
, pp. 1047-1059
-
-
Takaishi, K.1
Sasaki, T.2
Kotani, H.3
Nishioka, H.4
Takai, Y.5
-
46
-
-
0037079003
-
Rules for making human tumor cells
-
Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med 2002; 347:1593-603.
-
(2002)
N Engl J Med
, vol.347
, pp. 1593-1603
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
47
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
48
-
-
27744521323
-
Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors
-
Beeser A, Jaffer ZM, Hofmann C, Chernoff J. Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors. J Biol Chem 2005; 280:36609-15.
-
(2005)
J Biol Chem
, vol.280
, pp. 36609-36615
-
-
Beeser, A.1
Jaffer, Z.M.2
Hofmann, C.3
Chernoff, J.4
-
49
-
-
0036333485
-
Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes
-
Eblen ST, Slack JK, Weber MJ, Catling AD. Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes. Mol Cell Biol 2002; 22:6023-33.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6023-6033
-
-
Eblen, S.T.1
Slack, J.K.2
Weber, M.J.3
Catling, A.D.4
-
50
-
-
0347155585
-
Phosphorylation of p85 beta PIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth
-
Shin EY, Shin KS, Lee CS, Woo KN, Quan SH, Soung NK, Kim YG, Cha CI, Kim SR, Park D, Bokoch GM, Kim EG. Phosphorylation of p85 beta PIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth. J Biol Chem 2002; 277:44417-30.
-
(2002)
J Biol Chem
, vol.277
, pp. 44417-44430
-
-
Shin, E.Y.1
Shin, K.S.2
Lee, C.S.3
Woo, K.N.4
Quan, S.H.5
Soung, N.K.6
Kim, Y.G.7
Cha, C.I.8
Kim, S.R.9
Park, D.10
Bokoch, G.M.11
Kim, E.G.12
-
51
-
-
12544256298
-
Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation
-
Sundberg-Smith LJ, Doherty JT, Mack CP, Taylor JM. Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation. J Biol Chem 2005; 280:2055-64.
-
(2005)
J Biol Chem
, vol.280
, pp. 2055-2064
-
-
Sundberg-Smith, L.J.1
Doherty, J.T.2
Mack, C.P.3
Taylor, J.M.4
-
52
-
-
33751256003
-
-
Wildenberg GA, Dohn MR, Carnahan RH, Davis MA, Lobdell NA, Settleman J, Reynolds AB. p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell 2006; 127:1027-39.
-
Wildenberg GA, Dohn MR, Carnahan RH, Davis MA, Lobdell NA, Settleman J, Reynolds AB. p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell 2006; 127:1027-39.
-
-
-
-
53
-
-
33847236288
-
MEK/ERK regulates adherens junctions and migration through Rac1
-
Ray RM, Vaidya RJ, Johnson LR. MEK/ERK regulates adherens junctions and migration through Rac1. Cell Motil Cytoskeleton 2007; 64:143-56.
-
(2007)
Cell Motil Cytoskeleton
, vol.64
, pp. 143-156
-
-
Ray, R.M.1
Vaidya, R.J.2
Johnson, L.R.3
-
54
-
-
0042320953
-
Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesions by mitogen-activated protein kinases
-
Wu J, Sheibani N. Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesions by mitogen-activated protein kinases. J Cell Biochem 2003; 90:121-37.
-
(2003)
J Cell Biochem
, vol.90
, pp. 121-137
-
-
Wu, J.1
Sheibani, N.2
-
55
-
-
23144455311
-
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration
-
Rajalingam K, Wunder C, Brinkmann V, Churin Y, Hekman M, Sievers C, Rapp UR, Rudel T. Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration. Nat Cell Biol 2005; 7:837-43.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 837-843
-
-
Rajalingam, K.1
Wunder, C.2
Brinkmann, V.3
Churin, Y.4
Hekman, M.5
Sievers, C.6
Rapp, U.R.7
Rudel, T.8
-
56
-
-
34547957796
-
Flesh and blood: The story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies
-
Katzav S. Flesh and blood: The story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies. Cancer Lett 2007.
-
(2007)
Cancer Lett
-
-
Katzav, S.1
-
57
-
-
35848954347
-
Deleted in liver cancer-1 (DLC-1): A tumor suppressor not just for liver
-
Liao YC, Lo SH. Deleted in liver cancer-1 (DLC-1): A tumor suppressor not just for liver. Int J Biochem Cell Biol 2007.
-
(2007)
Int J Biochem Cell Biol
-
-
Liao, Y.C.1
SH, L.2
-
58
-
-
6344262173
-
An alternative transcript derived from the trio locus encodes a guanosine nucleotide exchange factor with mouse cell-transforming potential
-
Yoshizuka N, Moriuchi R, Mori T, Yamada K, Hasegawa S, Maeda T, Shimada T, Yamada Y, Kamihira S, Tomonaga M, Katamine S. An alternative transcript derived from the trio locus encodes a guanosine nucleotide exchange factor with mouse cell-transforming potential. J Biol Chem 2004; 279:43998-4004.
-
(2004)
J Biol Chem
, vol.279
, pp. 43998-44004
-
-
Yoshizuka, N.1
Moriuchi, R.2
Mori, T.3
Yamada, K.4
Hasegawa, S.5
Maeda, T.6
Shimada, T.7
Yamada, Y.8
Kamihira, S.9
Tomonaga, M.10
Katamine, S.11
-
59
-
-
3042550779
-
TRIO amplification and abundant mRNA expression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer
-
Zheng M, Simon R, Mirlacher M, Maurer R, Gasser T, Forster T, Diener PA, Mihatsch MJ, Sauter G, Schraml P. TRIO amplification and abundant mRNA expression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer. Am J Pathol 2004; 165:63-9.
-
(2004)
Am J Pathol
, vol.165
, pp. 63-69
-
-
Zheng, M.1
Simon, R.2
Mirlacher, M.3
Maurer, R.4
Gasser, T.5
Forster, T.6
Diener, P.A.7
Mihatsch, M.J.8
Sauter, G.9
Schraml, P.10
-
60
-
-
0037855764
-
Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma
-
Ching YP, Wong CM, Chan SF, Leung TH, Ng DC, Jin DY, Ng IO. Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma. J Biol Chem 2003; 278:10824-30.
-
(2003)
J Biol Chem
, vol.278
, pp. 10824-10830
-
-
Ching, Y.P.1
Wong, C.M.2
Chan, S.F.3
Leung, T.H.4
Ng, D.C.5
Jin, D.Y.6
Ng, I.O.7
-
61
-
-
34347333532
-
Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors
-
Ullmannova V, Popescu NC. Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors. Int J Oncol 2006; 29:1127-32.
-
(2006)
Int J Oncol
, vol.29
, pp. 1127-1132
-
-
Ullmannova, V.1
Popescu, N.C.2
-
62
-
-
12944262403
-
Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: Evidence for its fusion with MLL in acute myeloid leukemia
-
Kourlas PJ, Strout MP, Becknell B, Veronese ML, Croce CM, Theil KS, Krahe R, Ruutu T, Knuutila S, Bloomfield CD, Caligiuri MA. Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: Evidence for its fusion with MLL in acute myeloid leukemia. Proc Natl Acad Sci USA 2000; 97:2145-50.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2145-2150
-
-
Kourlas, P.J.1
Strout, M.P.2
Becknell, B.3
Veronese, M.L.4
Croce, C.M.5
Theil, K.S.6
Krahe, R.7
Ruutu, T.8
Knuutila, S.9
Bloomfield, C.D.10
Caligiuri, M.A.11
-
63
-
-
0035920247
-
Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA
-
Reuther GW, Lambert QT, Booden MA, Wennerberg K, Becknell B, Marcucci G, Sondek J, Caligiuri MA, Der CJ. Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA. J Biol Chem 2001; 276:27145-51.
-
(2001)
J Biol Chem
, vol.276
, pp. 27145-27151
-
-
Reuther, G.W.1
Lambert, Q.T.2
Booden, M.A.3
Wennerberg, K.4
Becknell, B.5
Marcucci, G.6
Sondek, J.7
Caligiuri, M.A.8
Der, C.J.9
-
64
-
-
12944277168
-
The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q
-
Borkhardt A, Bojesen S, Haas OA, Fuchs U, Bartelheimer D, Loncarevic IF, Bohle RM, Harbott J, Repp R, Jaeger U, Viehmann S, Henn T, Korth P, Scharr D, Lampert F. The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q. Proc Natl Acad Sci USA 2000; 97:9168-73.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9168-9173
-
-
Borkhardt, A.1
Bojesen, S.2
Haas, O.A.3
Fuchs, U.4
Bartelheimer, D.5
Loncarevic, I.F.6
Bohle, R.M.7
Harbott, J.8
Repp, R.9
Jaeger, U.10
Viehmann, S.11
Henn, T.12
Korth, P.13
Scharr, D.14
Lampert, F.15
-
65
-
-
11144338205
-
Activation of gef-h1, a guanine nucleotide exchange factor for RhoA, by DNA transfection
-
Brecht M, Steenvoorden AC, Collard JG, Luf S, Erz D, Bartram CR, Janssen JW. Activation of gef-h1, a guanine nucleotide exchange factor for RhoA, by DNA transfection. Int J Cancer 2005; 113:533-40.
-
(2005)
Int J Cancer
, vol.113
, pp. 533-540
-
-
Brecht, M.1
Steenvoorden, A.C.2
Collard, J.G.3
Luf, S.4
Erz, D.5
Bartram, C.R.6
Janssen, J.W.7
-
66
-
-
33745700179
-
Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cells
-
Mizuarai S, Yamanaka K, Kotani H. Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cells. Cancer Res 2006; 66:6319-26.
-
(2006)
Cancer Res
, vol.66
, pp. 6319-6326
-
-
Mizuarai, S.1
Yamanaka, K.2
Kotani, H.3
-
67
-
-
2542489234
-
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis
-
Lu KH, Patterson AP, Wang L, Marquez RT, Atkinson EN, Baggerly KA, Ramoth LR, Rosen DG, Liu J, Hellstrom I, Smith D, Hartmann L, Fishman D, Berchuck A, Schmandt R, Whitaker R, Gershenson DM, Mills GB, Bast Jr RC. Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. Clin Cancer Res 2004; 10:3291-300.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3291-3300
-
-
Lu, K.H.1
Patterson, A.P.2
Wang, L.3
Marquez, R.T.4
Atkinson, E.N.5
Baggerly, K.A.6
Ramoth, L.R.7
Rosen, D.G.8
Liu, J.9
Hellstrom, I.10
Smith, D.11
Hartmann, L.12
Fishman, D.13
Berchuck, A.14
Schmandt, R.15
Whitaker, R.16
Gershenson, D.M.17
Mills, G.B.18
Bast Jr, R.C.19
-
68
-
-
0026000012
-
Preferential expression of the dbl protooncogene in some tumors of neuroectodermal origin
-
de Franciscis V, Rosati R, Colucci-D'Amato GL, Eva A, Vecchio G. Preferential expression of the dbl protooncogene in some tumors of neuroectodermal origin. Cancer Res 1991; 51:4234-7.
-
(1991)
Cancer Res
, vol.51
, pp. 4234-4237
-
-
de Franciscis, V.1
Rosati, R.2
Colucci-D'Amato, G.L.3
Eva, A.4
Vecchio, G.5
-
69
-
-
0023635261
-
Independently activated dbl oncogenes exhibit similar yet distinct structural alterations
-
Eva A, Vecchio G, Diamond M, Tronick SR, Ron D, Cooper GM, Aaronson SA. Independently activated dbl oncogenes exhibit similar yet distinct structural alterations. Oncogene 1987; 1:355-60.
-
(1987)
Oncogene
, vol.1
, pp. 355-360
-
-
Eva, A.1
Vecchio, G.2
Diamond, M.3
Tronick, S.R.4
Ron, D.5
Cooper, G.M.6
Aaronson, S.A.7
-
70
-
-
33645026574
-
Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display
-
Carles A, Millon R, Cromer A, Ganguli G, Lemaire F, Young J, Wasylyk C, Muller D, Schultz I, Rabouel Y, Dembele D, Zhao C, Marchal P, Ducray C, Bracco L, Abecassis J, Poch O, Wasylyk B. Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display. Oncogene 2006; 25:1821-31.
-
(2006)
Oncogene
, vol.25
, pp. 1821-1831
-
-
Carles, A.1
Millon, R.2
Cromer, A.3
Ganguli, G.4
Lemaire, F.5
Young, J.6
Wasylyk, C.7
Muller, D.8
Schultz, I.9
Rabouel, Y.10
Dembele, D.11
Zhao, C.12
Marchal, P.13
Ducray, C.14
Bracco, L.15
Abecassis, J.16
Poch, O.17
Wasylyk, B.18
-
71
-
-
0027502565
-
Oncogene ect2 is related to regulators of small GTP-binding proteins
-
Miki T, Smith CL, Long JE, Eva A, Fleming TP. Oncogene ect2 is related to regulators of small GTP-binding proteins. Nature 1993; 362:462-5.
-
(1993)
Nature
, vol.362
, pp. 462-465
-
-
Miki, T.1
Smith, C.L.2
Long, J.E.3
Eva, A.4
Fleming, T.P.5
-
72
-
-
35848937194
-
Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients
-
Sano M, Genkai N, Yajima N, Tsuchiya N, Homma J, Tanaka R, Miki T, Yamanaka R. Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients. Oncol Rep 2006; 16:1093-8.
-
(2006)
Oncol Rep
, vol.16
, pp. 1093-1098
-
-
Sano, M.1
Genkai, N.2
Yajima, N.3
Tsuchiya, N.4
Homma, J.5
Tanaka, R.6
Miki, T.7
Yamanaka, R.8
-
73
-
-
0033862387
-
P190-B, a Rho-GTPase-activating protein, is differentially expressed in terminal end buds and breast cancer
-
Chakravarty G, Roy D, Gonzales M, Gay J, Contreras A, Rosen JM. P190-B, a Rho-GTPase-activating protein, is differentially expressed in terminal end buds and breast cancer. Cell Growth Differ 2000; 11:343-54.
-
(2000)
Cell Growth Differ
, vol.11
, pp. 343-354
-
-
Chakravarty, G.1
Roy, D.2
Gonzales, M.3
Gay, J.4
Contreras, A.5
Rosen, J.M.6
-
75
-
-
0028110120
-
A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways
-
Horii Y, Beeler JF, Sakaguchi K, Tachibana M, Miki T. A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways. Embo J 1994; 13:4776-86.
-
(1994)
Embo J
, vol.13
, pp. 4776-4786
-
-
Horii, Y.1
Beeler, J.F.2
Sakaguchi, K.3
Tachibana, M.4
Miki, T.5
-
76
-
-
0033815830
-
Tiam1 mutations in human renal-cell carcinomas
-
Engers R, Zwaka TP, Gohr L, Weber A, Gerharz CD, Gabbert HE. Tiam1 mutations in human renal-cell carcinomas. Int J Cancer 2000; 88:369-76.
-
(2000)
Int J Cancer
, vol.88
, pp. 369-376
-
-
Engers, R.1
Zwaka, T.P.2
Gohr, L.3
Weber, A.4
Gerharz, C.D.5
Gabbert, H.E.6
-
77
-
-
1642343506
-
The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression
-
Minard ME, Kim LS, Price JE, Gallick GE. The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression. Breast Cancer Res Treat 2004; 84:21-32.
-
(2004)
Breast Cancer Res Treat
, vol.84
, pp. 21-32
-
-
Minard, M.E.1
Kim, L.S.2
Price, J.E.3
Gallick, G.E.4
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