Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor-null mice

Circulation

Volumn 116, Issue 19, 2007, Pages 2182-2190

  Thorp, Edward ^a   Kuriakose, George ^a   Shah, Yatrik M ^b   Gonzalez, Frank J ^b   Tabas, Ira ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Apoptosis; Atherosclerosis; Drugs; Macrophages; Plaque

Indexed keywords

GLITAZONE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; ROSIGLITAZONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; AORTA ROOT; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL SURVIVAL; CHOLESTEROL DIET; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; FEMALE; MACROPHAGE; MOUSE; NONHUMAN; NULL ALLELE; PHAGOCYTOSIS; PRIORITY JOURNAL; TREATMENT OUTCOME; WILD TYPE;

ANIMALS; APOPTOSIS; ATHEROSCLEROSIS; CELL SURVIVAL; CHOLESTEROL; DIABETES MELLITUS, TYPE 2; FEMALE; HYPOGLYCEMIC AGENTS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NECROSIS; PPAR GAMMA; RECEPTORS, LDL; THIAZOLIDINEDIONES; TRANSCRIPTION FACTOR RELA;

EID: 35848933241     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.698852     Document Type: Article

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