Glutathione depletion down-regulates tumor necrosis factor α-induced NF-κB activity via IκB kinase-dependent and -independent mechanisms

Journal of Biological Chemistry

Volumn 282, Issue 40, 2007, Pages 29470-29481

  Lou, Huan ^a   Kaplowitz, Neil ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CELL CULTURE; CELL DEATH; ENZYME INHIBITION; GENE EXPRESSION; TUMORS;

HEPATOCYTE FUNCTION; INTERACTING PROTEINS; POLYUBIQUITINATION; REDUCED GLUTATHIONE (GSH);

ENZYME ACTIVITY;

DNA; GLUTATHIONE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRANSCRIPTION INITIATION; UBIQUITINATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIOXIDANTS; DOWN-REGULATION; GLUTATHIONE; I-KAPPA B KINASE; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHOSPHORYLATION; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; TUMOR NECROSIS FACTOR-ALPHA;

EID: 35748961980     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706145200     Document Type: Article

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