-
1
-
-
1942485807
-
Sigma-1 receptor ligands: Potential in the treatment of neuropsychiatric disorders
-
Hayashi T, Su TP. Sigma-1 receptor ligands: potential in the treatment of neuropsychiatric disorders. CNS Drugs. 2004;18:269-284.
-
(2004)
CNS Drugs
, vol.18
, pp. 269-284
-
-
Hayashi, T.1
Su, T.P.2
-
2
-
-
0026567933
-
A proposal for the classification of sigma binding sites
-
Quirion R, Bowen WD, Itzhak JL, et al. A proposal for the classification of sigma binding sites. Trends Pharmacol Sci. 1992;13:85-86.
-
(1992)
Trends Pharmacol Sci
, vol.13
, pp. 85-86
-
-
Quirion, R.1
Bowen, W.D.2
Itzhak, J.L.3
-
3
-
-
0029797712
-
Purification, molecular cloning, and expression of the mammalian sigma 1-binding site
-
Hanner M, Moebius FF, Flandorfer A, et al. Purification, molecular cloning, and expression of the mammalian sigma 1-binding site. Proc Natl Acad Sci USA. 1996;93:8072-8077.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8072-8077
-
-
Hanner, M.1
Moebius, F.F.2
Flandorfer, A.3
-
4
-
-
0030582657
-
Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1)
-
Kekuda R, Prasad PD, Fei YJ, et al. Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1). Biochem Biophys Res Commun. 1996;229:553-558.
-
(1996)
Biochem Biophys Res Commun
, vol.229
, pp. 553-558
-
-
Kekuda, R.1
Prasad, P.D.2
Fei, Y.J.3
-
5
-
-
0031913686
-
Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene
-
Prasad PD, Li HW, Fei YJ, et al. Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene. J Neurochem. 1998;70:443-451.
-
(1998)
J Neurochem
, vol.70
, pp. 443-451
-
-
Prasad, P.D.1
Li, H.W.2
Fei, Y.J.3
-
6
-
-
0031577794
-
Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor
-
Seth P, Leibach FH, Ganapathy V. Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor. Biochem Biophys Res Commun. 1997;241:535-540.
-
(1997)
Biochem Biophys Res Commun
, vol.241
, pp. 535-540
-
-
Seth, P.1
Leibach, F.H.2
Ganapathy, V.3
-
7
-
-
0031892683
-
Cloning and functional characterization σ from rat brain
-
Seth P, Fei YJ, Li HW, et al. Cloning and functional characterization σ from rat brain. J Neurochem. 1998;70:922-931.
-
(1998)
J Neurochem
, vol.70
, pp. 922-931
-
-
Seth, P.1
Fei, Y.J.2
Li, H.W.3
-
8
-
-
0028861513
-
Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site
-
Yamamoto H, Yamamoto T, Sagi N, et al. Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site. J Neurosci. 1995;15:731-736.
-
(1995)
J Neurosci
, vol.15
, pp. 731-736
-
-
Yamamoto, H.1
Yamamoto, T.2
Sagi, N.3
-
9
-
-
0031787840
-
Potent σ1-receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine modulates basal and N-methyl-D- aspartate-evoked nitric oxide production in vivo
-
Bhardwaj A, Sawada M, London ED, et al. Potent σ1-receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine modulates basal and N-methyl-D- aspartate-evoked nitric oxide production in vivo. Stroke. 1998;29:2404-2411.
-
(1998)
Stroke
, vol.29
, pp. 2404-2411
-
-
Bhardwaj, A.1
Sawada, M.2
London, E.D.3
-
10
-
-
0028884779
-
Role of calcium in sigma-mediated neuroprotection in rat primary cortical cultures
-
Klette KL, DeCoster MA, Moreton JE, et al. Role of calcium in sigma-mediated neuroprotection in rat primary cortical cultures. Brain Res. 1995;704:31-41.
-
(1995)
Brain Res
, vol.704
, pp. 31-41
-
-
Klette, K.L.1
DeCoster, M.A.2
Moreton, J.E.3
-
11
-
-
33751186935
-
Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia
-
Katnik C, Guerrero WR, Pennypacker KR, et al. Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia. J Pharmacol Exp Ther. 2006;319:1355-1365.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 1355-1365
-
-
Katnik, C.1
Guerrero, W.R.2
Pennypacker, K.R.3
-
12
-
-
0025197009
-
σ-Ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia
-
Lobner D, Lipton P. σ-Ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia. Neurosci Lett. 1990;117:169-174.
-
(1990)
Neurosci Lett
, vol.117
, pp. 169-174
-
-
Lobner, D.1
Lipton, P.2
-
13
-
-
0028950943
-
Distinct neuroprotective profiles for σ-ligands against N-methyl-D-aspartate (NMDA), and hypoxia-mediated neurotoxicity in neuronal culture toxicity studies
-
Lockhart BP, Soulard P, Benicourt C, et al. Distinct neuroprotective profiles for σ-ligands against N-methyl-D-aspartate (NMDA), and hypoxia-mediated neurotoxicity in neuronal culture toxicity studies. Brain Res. 1995;675:110-120.
-
(1995)
Brain Res
, vol.675
, pp. 110-120
-
-
Lockhart, B.P.1
Soulard, P.2
Benicourt, C.3
-
14
-
-
33746480370
-
Sigma 1 receptor agonists act as neuroprotective drugs through inhibition of inducible nitric oxide synthase
-
Vagnerova K, Hurn PD, Bhardwaj A, et al. Sigma 1 receptor agonists act as neuroprotective drugs through inhibition of inducible nitric oxide synthase. Anesth Analg. 2006;103:430-434.
-
(2006)
Anesth Analg
, vol.103
, pp. 430-434
-
-
Vagnerova, K.1
Hurn, P.D.2
Bhardwaj, A.3
-
16
-
-
0032589265
-
Sigma 1 recognition sites in rabbit iris-ciliary body: Topical sigma 1-site ligands lower intraocular pressure
-
Bucolo C, Campana C, Di Toro R, et al. Sigma 1 recognition sites in rabbit iris-ciliary body: topical sigma 1-site ligands lower intraocular pressure. J Pharmacol Exp Ther. 1999;289:1362-1369.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 1362-1369
-
-
Bucolo, C.1
Campana, C.2
Di Toro, R.3
-
17
-
-
0035500397
-
Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina
-
Ola MS, Moore PM, El-Sherbeny A, et al. Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina. Mol Brain Res. 2001;95:86-95.
-
(2001)
Mol Brain Res
, vol.95
, pp. 86-95
-
-
Ola, M.S.1
Moore, P.M.2
El-Sherbeny, A.3
-
18
-
-
33646021588
-
Silencing of sigma-1 receptor induces cell death in human lens cells
-
Wang L, Duncan G. Silencing of sigma-1 receptor induces cell death in human lens cells. Exp Cell Res. 2006;312:1439-1446.
-
(2006)
Exp Cell Res
, vol.312
, pp. 1439-1446
-
-
Wang, L.1
Duncan, G.2
-
19
-
-
0031011056
-
The presence of sigma receptor subtypes in bovine retinal membranes
-
Senda T, Matsuno K, Mita S. The presence of sigma receptor subtypes in bovine retinal membranes. Exp Eye Res. 1997;64:857-860.
-
(1997)
Exp Eye Res
, vol.64
, pp. 857-860
-
-
Senda, T.1
Matsuno, K.2
Mita, S.3
-
20
-
-
0037111911
-
Analysis of sigma receptor (σR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice
-
Ola MS, Martin PM, Maddox D, et al. Analysis of sigma receptor (σR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice. Brain Res Mol Brain Res. 2002;107:97-107.
-
(2002)
Brain Res Mol Brain Res
, vol.107
, pp. 97-107
-
-
Ola, M.S.1
Martin, P.M.2
Maddox, D.3
-
21
-
-
34248198347
-
Expression, subcellular localization and regulation of sigma receptor in retinal Müller cells
-
Jiang G, Mysona B, Dun Y, et al. Expression, subcellular localization and regulation of sigma receptor in retinal Müller cells. Invest Ophthamol Vis Sci. 2006;47:5576-558.
-
(2006)
Invest Ophthamol Vis Sci
, vol.47
, pp. 5576-6558
-
-
Jiang, G.1
Mysona, B.2
Dun, Y.3
-
23
-
-
0036710971
-
Retinal ganglion cell disorders: Types and treatments
-
Levin LA, Gordon LK. Retinal ganglion cell disorders: types and treatments. Prog Retin Eye Res. 2002;21:465-484.
-
(2002)
Prog Retin Eye Res
, vol.21
, pp. 465-484
-
-
Levin, L.A.1
Gordon, L.K.2
-
24
-
-
0024385291
-
Synthesis and evaluation of optically pure [3H]-(+)-pentazocine, a highly potent and selective radioligand for sigma receptors
-
de Costa BR, Bowen WD, Hellewell SB, et al. Synthesis and evaluation of optically pure [3H]-(+)-pentazocine, a highly potent and selective radioligand for sigma receptors. FEBS Lett. 1989;251:53-58.
-
(1989)
FEBS Lett
, vol.251
, pp. 53-58
-
-
de Costa, B.R.1
Bowen, W.D.2
Hellewell, S.B.3
-
25
-
-
1642279907
-
The sigma receptor (σR) Iigand (+)-pentazocine prevents retinal ganglion cell death induced in vitro by homocysteine and glutamate
-
Martin PM, Ola MS, Agarwal N, et al. The sigma receptor (σR) Iigand (+)-pentazocine prevents retinal ganglion cell death induced in vitro by homocysteine and glutamate. Brain Res Mol Brain Res. 2004;123:66-75.
-
(2004)
Brain Res Mol Brain Res
, vol.123
, pp. 66-75
-
-
Martin, P.M.1
Ola, M.S.2
Agarwal, N.3
-
26
-
-
0034775253
-
Apoptotic retinal ganglion cell death is induced in vivo by the excitatory amino acid homocysteine
-
Moore P, El-Sherbeny A, Roon P, et al. Apoptotic retinal ganglion cell death is induced in vivo by the excitatory amino acid homocysteine. Exp Eye Res. 2001;73:45-57.
-
(2001)
Exp Eye Res
, vol.73
, pp. 45-57
-
-
Moore, P.1
El-Sherbeny, A.2
Roon, P.3
-
27
-
-
33645821925
-
-) exchanger in cultured retinal ganglion cells and regulation by nitric oxide and oxidative stress
-
-) exchanger in cultured retinal ganglion cells and regulation by nitric oxide and oxidative stress. Cell Tiss Res. 2006;324:189-202.
-
(2006)
Cell Tiss Res
, vol.324
, pp. 189-202
-
-
Dun, Y.1
Mysona, B.2
Van Ells, T.K.3
-
28
-
-
0033983288
-
B vitamins, homocysteine, and neurocognitive function in the elderly
-
Selhub J, Bagley LC, Miller J, et al. B vitamins, homocysteine, and neurocognitive function in the elderly. Am J Clin Nutr. 2000;71(suppl):614S-620S.
-
(2000)
Am J Clin Nutr
, vol.71
, Issue.SUPPL.
-
-
Selhub, J.1
Bagley, L.C.2
Miller, J.3
-
29
-
-
4344575903
-
Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease
-
Austin RC, Lentz SR, Werstuck GH. Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease. Cell Death Differ. 2004;(suppl 1):S56-S64.
-
(2004)
Cell Death Differ
, Issue.SUPPL. 1
-
-
Austin, R.C.1
Lentz, S.R.2
Werstuck, G.H.3
-
30
-
-
0037364417
-
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders
-
Mattson MP, Shea TB. Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders. Trends Neurosci. 2003;26:137-146.
-
(2003)
Trends Neurosci
, vol.26
, pp. 137-146
-
-
Mattson, M.P.1
Shea, T.B.2
-
31
-
-
0036784055
-
Relation of blood homocysteine and its nutritional determinants to age-related maculopathy in the third National Health and Nutrition Examination Survey
-
Heuberger RA, Fisher AI, Jacques PF, et al. Relation of blood homocysteine and its nutritional determinants to age-related maculopathy in the third National Health and Nutrition Examination Survey. Am J Clin Nutr. 2002;76:897-902.
-
(2002)
Am J Clin Nutr
, vol.76
, pp. 897-902
-
-
Heuberger, R.A.1
Fisher, A.I.2
Jacques, P.F.3
-
32
-
-
0346099260
-
Association of neovascular age-related macular degeneration and hyperhomocysteinemia
-
Axer-Siegel R, Bouria D, Ehrlich R, et al. Association of neovascular age-related macular degeneration and hyperhomocysteinemia. Am J Ophthalmol. 2004;137:84-89.
-
(2004)
Am J Ophthalmol
, vol.137
, pp. 84-89
-
-
Axer-Siegel, R.1
Bouria, D.2
Ehrlich, R.3
-
33
-
-
0036108627
-
Hyperhomocyst(e)inemia, but not methylenetetrahydrofolate reductase C677T mutation, as a risk factor in branch retinal vein occlusion
-
Weger M, Stanger O, Deutschmann H, et al. Hyperhomocyst(e)inemia, but not methylenetetrahydrofolate reductase C677T mutation, as a risk factor in branch retinal vein occlusion. Ophthalmolmology. 2002;109:1105-1109.
-
(2002)
Ophthalmolmology
, vol.109
, pp. 1105-1109
-
-
Weger, M.1
Stanger, O.2
Deutschmann, H.3
-
34
-
-
0036926376
-
Homocysteine and risk of open-angle glaucoma
-
Bleich S, Junemann A, von Ahsen N, et al. Homocysteine and risk of open-angle glaucoma. J Neural Transnt. 2002;109:1499-1504.
-
(2002)
J Neural Transnt
, vol.109
, pp. 1499-1504
-
-
Bleich, S.1
Junemann, A.2
von Ahsen, N.3
-
35
-
-
3042826856
-
Elevated homocysteine levels in aqueous humor of patients with Pseudoexfoliation glaucoma
-
Bleich S, Roedl J, Von Ahsen N, et al. Elevated homocysteine levels in aqueous humor of patients with Pseudoexfoliation glaucoma. Am J Ophthalmol. 2004;138:162-164.
-
(2004)
Am J Ophthalmol
, vol.138
, pp. 162-164
-
-
Bleich, S.1
Roedl, J.2
Von Ahsen, N.3
-
36
-
-
0036372477
-
The impact of plasma homocysteine level on development of retinopathy in type 2 diabetes mellitus
-
Yang G, Lu J, Pan C. The impact of plasma homocysteine level on development of retinopathy in type 2 diabetes mellitus. Zhonghua Net Ke Za Zhi. 2002;41:34-38.
-
(2002)
Zhonghua Net Ke Za Zhi
, vol.41
, pp. 34-38
-
-
Yang, G.1
Lu, J.2
Pan, C.3
-
37
-
-
0344441344
-
Meta-analysis of plasma homocysteine, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease
-
Cahill MT, Stinnett SS, Fekrat S. Meta-analysis of plasma homocysteine, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease. Am J Ophthalmol. 2003;136:1136-1150.
-
(2003)
Am J Ophthalmol
, vol.136
, pp. 1136-1150
-
-
Cahill, M.T.1
Stinnett, S.S.2
Fekrat, S.3
-
38
-
-
29544443447
-
Evaluation of plasma homocysteine and risk of age-related macular degeneration
-
Seddon JM, Gensler G, Klein ML, et al. Evaluation of plasma homocysteine and risk of age-related macular degeneration. Am J Ophthalmol. 2006;141:201-203.
-
(2006)
Am J Ophthalmol
, vol.141
, pp. 201-203
-
-
Seddon, J.M.1
Gensler, G.2
Klein, M.L.3
-
39
-
-
26844523529
-
Branch retinal artery occlusion in a young man with hyperhomocysteinemia
-
Wang NC, Lai CC, Chen TL, et al. Branch retinal artery occlusion in a young man with hyperhomocysteinemia. Retina. 2005;25:940-942.
-
(2005)
Retina
, vol.25
, pp. 940-942
-
-
Wang, N.C.1
Lai, C.C.2
Chen, T.L.3
-
40
-
-
20444483337
-
Disturbed visual system function in methionine synthase deficiency
-
Poloschek CM, Fowler B, Unsold R, et al. Disturbed visual system function in methionine synthase deficiency. Graefe's Arch Ophthalmol. 2005;243:497-500.
-
(2005)
Graefe's Arch Ophthalmol
, vol.243
, pp. 497-500
-
-
Poloschek, C.M.1
Fowler, B.2
Unsold, R.3
-
41
-
-
0029868452
-
Peroxynitrite inhibits glutamate transporter subtypes
-
Trotti D, Rossi D, Gjesdal O, et al. Peroxynitrite inhibits glutamate transporter subtypes. J Biol Chem. 1996;271:5976-5979.
-
(1996)
J Biol Chem
, vol.271
, pp. 5976-5979
-
-
Trotti, D.1
Rossi, D.2
Gjesdal, O.3
-
42
-
-
33751399402
-
Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli
-
Ramachandran S, Lu H, Prabhu U, Ruoho AE. Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli. Protein Expr Purif. 2007;51:283-392.
-
(2007)
Protein Expr Purif
, vol.51
, pp. 283-392
-
-
Ramachandran, S.1
Lu, H.2
Prabhu, U.3
Ruoho, A.E.4
-
44
-
-
0037960938
-
Intracellular dynamics of sigma-1 receptors (sigma(1) binding sites) in NG108-15 cells
-
Hayashi T, Su TP. Intracellular dynamics of sigma-1 receptors (sigma(1) binding sites) in NG108-15 cells. J Pharmacol Exp Ther. 2003;306:726-733.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 726-733
-
-
Hayashi, T.1
Su, T.P.2
|