메뉴 건너뛰기




Volumn 71, Issue 2, 2000, Pages

B vitamins, homocysteine, and neurocognitive function in the elderly

Author keywords

Aging; Alzheimer disease; B vitamins; Brain; Cognitive decline; Cognitive function; Dementia; Elderly; Folate; Folic acid; Homocysteine; Hyperhomocysteinemia; Vitamin B 6; Vitamin B 12

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; PYRIDOXINE; VITAMIN B GROUP;

EID: 0033983288     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/71.2.614s     Document Type: Conference Paper
Times cited : (391)

References (48)
  • 2
    • 0018654625 scopus 로고
    • Increased taste thresholds of amino acids with age
    • Schiffman SS, Hornack K, Reilly D. Increased taste thresholds of amino acids with age. Am J Clin Nutr 1979;32:1622-7.
    • (1979) Am J Clin Nutr , vol.32 , pp. 1622-1627
    • Schiffman, S.S.1    Hornack, K.2    Reilly, D.3
  • 3
    • 0030770405 scopus 로고    scopus 로고
    • Role of homocysteine in age-related vascular and non-vascular diseases
    • Milano
    • Parnetti L, Bottiglieri T, Lowenthal D. Role of homocysteine in age-related vascular and non-vascular diseases. Aging (Milano) 1997; 9:241-57.
    • (1997) Aging , vol.9 , pp. 241-257
    • Parnetti, L.1    Bottiglieri, T.2    Lowenthal, D.3
  • 4
    • 0030299046 scopus 로고    scopus 로고
    • Folate, vitamin B12, and neuropsychiatric disorders
    • Bottiglieri T. Folate, vitamin B12, and neuropsychiatric disorders. Nutr Rev 1996;54:382-90.
    • (1996) Nutr Rev , vol.54 , pp. 382-390
    • Bottiglieri, T.1
  • 7
    • 0023019331 scopus 로고
    • Fundic atrophic gastritis in an elderly population: Effect on hemoglobin and several serum nutritional indicators
    • Krasinski SD, Russell RM, Samloff IM, et al. Fundic atrophic gastritis in an elderly population: effect on hemoglobin and several serum nutritional indicators. J Am Geriatr Soc 1986;34:800-6.
    • (1986) J Am Geriatr Soc , vol.34 , pp. 800-806
    • Krasinski, S.D.1    Russell, R.M.2    Samloff, I.M.3
  • 9
    • 0018573105 scopus 로고
    • Influence of intraluminal pH on folate absorption: Studies in control subjects and in patients with pancreatic insufficiency
    • Russell RM, Dhar GJ, Dutta SK, Rosenberg IH. Influence of intraluminal pH on folate absorption: studies in control subjects and in patients with pancreatic insufficiency. J Lab Clin Med 1979;93: 428-36.
    • (1979) J Lab Clin Med , vol.93 , pp. 428-436
    • Russell, R.M.1    Dhar, G.J.2    Dutta, S.K.3    Rosenberg, I.H.4
  • 10
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Selhub J, Jacques PF, Wilson PWF, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993;270:2693-8.
    • (1993) JAMA , vol.270 , pp. 2693-2698
    • Selhub, J.1    Jacques, P.F.2    Wilson, P.W.F.3    Rush, D.4    Rosenberg, I.H.5
  • 11
    • 0020582844 scopus 로고
    • Association between nutritional status and cognitive functioning in a healthy elderly population
    • Goodwin JS, Goodwin JM, Garry PJ. Association between nutritional status and cognitive functioning in a healthy elderly population. JAMA 1983;249:2917-21.
    • (1983) JAMA , vol.249 , pp. 2917-2921
    • Goodwin, J.S.1    Goodwin, J.M.2    Garry, P.J.3
  • 12
    • 0023143179 scopus 로고
    • Low serum cobalamin levels in primary degenerative dementia
    • Karnaze DS, Carmel R. Low serum cobalamin levels in primary degenerative dementia. Arch Intern Med 1987;147:429-31.
    • (1987) Arch Intern Med , vol.147 , pp. 429-431
    • Karnaze, D.S.1    Carmel, R.2
  • 13
    • 0023946537 scopus 로고
    • Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis
    • Lindenbaum J, Healton EB, Savage DG, et al. Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med 1988;318:1720-8.
    • (1988) N Engl J Med , vol.318 , pp. 1720-1728
    • Lindenbaum, J.1    Healton, E.B.2    Savage, D.G.3
  • 16
    • 0025093135 scopus 로고
    • Vitamin B12 and folate concentrations in serum and cerbrospinal fluid of neurological patients with special reference to multiple sclerosis and dementia
    • Nijst TQ, Wevers RA, Schoonderwaldt HC, Hommes OR, Haan AFJ. Vitamin B12 and folate concentrations in serum and cerbrospinal fluid of neurological patients with special reference to multiple sclerosis and dementia. J Neurol Neurosurg Psychiatry 1990;53:951-4.
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , pp. 951-954
    • Nijst, T.Q.1    Wevers, R.A.2    Schoonderwaldt, H.C.3    Hommes, O.R.4    Haan, A.F.J.5
  • 17
    • 0026443092 scopus 로고
    • Plasma homocysteine in vascular disease and in nonvascular dementia of depressed elderly people
    • Bell IR, Edman JS, Selhub J, et al. Plasma homocysteine in vascular disease and in nonvascular dementia of depressed elderly people. Acta Psychiatr Scand 1992;86:386-90.
    • (1992) Acta Psychiatr Scand , vol.86 , pp. 386-390
    • Bell, I.R.1    Edman, J.S.2    Selhub, J.3
  • 18
    • 0026613626 scopus 로고
    • Folate, vitamin B12 and cognitive impairment in patients with Alzheimer's disease
    • Levitt AJ, Karlinsky H. Folate, vitamin B12 and cognitive impairment in patients with Alzheimer's disease. Acta Psychiatr Scand 1992;86:301-5.
    • (1992) Acta Psychiatr Scand , vol.86 , pp. 301-305
    • Levitt, A.J.1    Karlinsky, H.2
  • 20
    • 0028170372 scopus 로고
    • Vitamin B12 levels and incidence of dementia in a healthy elderly population: A report from the Bronx Longitudinal Aging Study
    • Crystal HA, Ortof E, Frishman WH, Gruber A, Hershman D, Aronson M. Vitamin B12 levels and incidence of dementia in a healthy elderly population: a report from the Bronx Longitudinal Aging Study. J Am Geriatr Soc 1994;42:933-6.
    • (1994) J Am Geriatr Soc , vol.42 , pp. 933-936
    • Crystal, H.A.1    Ortof, E.2    Frishman, W.H.3    Gruber, A.4    Hershman, D.5    Aronson, M.6
  • 21
    • 0029827897 scopus 로고    scopus 로고
    • Hyperhomocysteinaemia - A common finding in psychogeriatric population
    • Nilsson K, Gustafson L, Faldt R, et al. Hyperhomocysteinaemia - a common finding in psychogeriatric population. Eur J Clin Invest 1996;26:853-9.
    • (1996) Eur J Clin Invest , vol.26 , pp. 853-859
    • Nilsson, K.1    Gustafson, L.2    Faldt, R.3
  • 22
    • 0029742098 scopus 로고    scopus 로고
    • Functional and psychic deterioration in elderly people may be aggravated by folate deficiency
    • Ortega RM, Manas LR, Andres P, et al. Functional and psychic deterioration in elderly people may be aggravated by folate deficiency. J Nutr 1996;126:1992-6.
    • (1996) J Nutr , vol.126 , pp. 1992-1996
    • Ortega, R.M.1    Manas, L.R.2    Andres, P.3
  • 23
    • 0029842566 scopus 로고    scopus 로고
    • Estimation of vitamin needsóriboflavin, vitamin B-6 and ascorbic acidóaccording to blood parameters and functional, cognitive and emotional indices in a selected well-established group of elderly in a home for the aged in Israel
    • Dror Y, Stern F, Nemesh L, Hart J, Grinblat J. Estimation of vitamin needsóriboflavin, vitamin B-6 and ascorbic acidóaccording to blood parameters and functional, cognitive and emotional indices in a selected well-established group of elderly in a home for the aged in Israel. J Am Coll Nutr 1996;15:481-8.
    • (1996) J Am Coll Nutr , vol.15 , pp. 481-488
    • Dror, Y.1    Stern, F.2    Nemesh, L.3    Hart, J.4    Grinblat, J.5
  • 24
    • 0029865065 scopus 로고    scopus 로고
    • Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study
    • Riggs KM, Spiro A III, Tucker K, Rush D. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. Am J Clin Nutr 1996; 63:306-14.
    • (1996) Am J Clin Nutr , vol.63 , pp. 306-314
    • Riggs, K.M.1    Spiro A. III2    Tucker, K.3    Rush, D.4
  • 26
    • 0031003514 scopus 로고    scopus 로고
    • Is metabolic evidence for vitamin B12 and folate deficiency more frequent in elderly patients with Alzheimer's disease?
    • Joosten E, Lesaffre E, Riezler R, et al. Is metabolic evidence for vitamin B12 and folate deficiency more frequent in elderly patients with Alzheimer's disease? J Gerontol A Biol Sci Med Sci 1997;52: M76-9.
    • (1997) J Gerontol A Biol Sci Med Sci , vol.52
    • Joosten, E.1    Lesaffre, E.2    Riezler, R.3
  • 27
    • 0031597388 scopus 로고    scopus 로고
    • Folate, vitamin B12 and serum total homocysteine in confirmed Alzheimer's disease
    • Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM. Folate, vitamin B12 and serum total homocysteine in confirmed Alzheimer's disease. Arch Neurol 1998;55:1449-55.
    • (1998) Arch Neurol , vol.55 , pp. 1449-1455
    • Clarke, R.1    Smith, A.D.2    Jobst, K.A.3    Refsum, H.4    Sutton, L.5    Ueland, P.M.6
  • 28
    • 0030971062 scopus 로고    scopus 로고
    • Homocysteine and thrombotic disease
    • D'Angelo A, Selhub J. Homocysteine and thrombotic disease. Blood 1997;90:1-11.
    • (1997) Blood , vol.90 , pp. 1-11
    • D'Angelo, A.1    Selhub, J.2
  • 29
    • 0030917545 scopus 로고    scopus 로고
    • Putative mechanisms for vascular damage by homocysteine
    • Bellamy MF, McDowell IF. Putative mechanisms for vascular damage by homocysteine. J Inherit Metab Dis 1997;20:307-15.
    • (1997) J Inherit Metab Dis , vol.20 , pp. 307-315
    • Bellamy, M.F.1    McDowell, I.F.2
  • 30
    • 0026445841 scopus 로고
    • Vitamin B-6 supplementation in elderly men: Effects on mood, memory, performance and mental effort
    • Deifen JB, Beek EJ, Orlebeke JF, Berg H. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort. Psychopharmacology 1992;109:489-96.
    • (1992) Psychopharmacology , vol.109 , pp. 489-496
    • Deifen, J.B.1    Beek, E.J.2    Orlebeke, J.F.3    Berg, H.4
  • 31
    • 0026559270 scopus 로고
    • Time dependency of cognitive recovery with cobalamin replacement: Report of a pilot study
    • Martin DC, Francis J, Protetch J, Huff FJ. Time dependency of cognitive recovery with cobalamin replacement: report of a pilot study. J Am Geriatr Soc 1992;40:168-72.
    • (1992) J Am Geriatr Soc , vol.40 , pp. 168-172
    • Martin, D.C.1    Francis, J.2    Protetch, J.3    Huff, F.J.4
  • 32
    • 0018241209 scopus 로고
    • Beta adrenergic stimulation of protein carboxymethylation and amylase secretion in rat parotid gland
    • Strittmatter WJ, Gagnon C, Axelrod J. Beta adrenergic stimulation of protein carboxymethylation and amylase secretion in rat parotid gland. J Pharmacol Exp Ther 1978;207:419-24.
    • (1978) J Pharmacol Exp Ther , vol.207 , pp. 419-424
    • Strittmatter, W.J.1    Gagnon, C.2    Axelrod, J.3
  • 33
    • 0013886618 scopus 로고
    • Methylation reactions in the formation and metabolism of catecholamines and other biogenic amines
    • Axelrod J. Methylation reactions in the formation and metabolism of catecholamines and other biogenic amines. Pharmacol Rev 1966;18:95-113.
    • (1966) Pharmacol Rev , vol.18 , pp. 95-113
    • Axelrod, J.1
  • 34
    • 0020491032 scopus 로고
    • Enzymatic methylation of the membrane-bound nicotinic acetylcholine receptor
    • Flynn DD, Kloog Y, Potter LT, Axelrod J. Enzymatic methylation of the membrane-bound nicotinic acetylcholine receptor. J Biol Chem 1982;257:9513-7.
    • (1982) J Biol Chem , vol.257 , pp. 9513-9517
    • Flynn, D.D.1    Kloog, Y.2    Potter, L.T.3    Axelrod, J.4
  • 35
    • 0019732323 scopus 로고
    • Phospholipid methylation and membrane function
    • Axelrod J, Hirata F. Phospholipid methylation and membrane function. Ann N Y Acad Sci 1981;373:51-3.
    • (1981) Ann N Y Acad Sci , vol.373 , pp. 51-53
    • Axelrod, J.1    Hirata, F.2
  • 36
    • 0018973408 scopus 로고
    • Reversible dementia and neuropathy associated with folate deficiency 16 years after partial gastrectomy
    • Enk D, Hougaard K, Hippe E. Reversible dementia and neuropathy associated with folate deficiency 16 years after partial gastrectomy. Scand J Haematol 1980;25:63-6.
    • (1980) Scand J Haematol , vol.25 , pp. 63-66
    • Enk, D.1    Hougaard, K.2    Hippe, E.3
  • 37
    • 0026720760 scopus 로고
    • Nutritional factors in physical and cognitive functions of elderly people
    • Rosenberg IH, Miller JW. Nutritional factors in physical and cognitive functions of elderly people. Am J Clin Nutr 1992;55: 1237S-43S.
    • (1992) Am J Clin Nutr , vol.55
    • Rosenberg, I.H.1    Miller, J.W.2
  • 39
    • 0024231990 scopus 로고
    • Methylation deficiency causes vitamin B12 associated neuropathy in the pig
    • Weir DG, Keating S, Molloy A, et al. Methylation deficiency causes vitamin B12 associated neuropathy in the pig. J Neurochem 1988; 51:1949-52.
    • (1988) J Neurochem , vol.51 , pp. 1949-1952
    • Weir, D.G.1    Keating, S.2    Molloy, A.3
  • 40
    • 0028102526 scopus 로고
    • The clinical potential of ademetionine (Sadenosylmethionine) in neurological disorders
    • Bottiglieri T, Hyland K, Reynolds EH. The clinical potential of ademetionine (Sadenosylmethionine) in neurological disorders. Drugs 1994;48:137-52.
    • (1994) Drugs , vol.48 , pp. 137-152
    • Bottiglieri, T.1    Hyland, K.2    Reynolds, E.H.3
  • 42
    • 0021342568 scopus 로고
    • Open trial of S-adenosylmethionine for treatment of depression
    • Lipinski JF, Cohen BM, Frankenberg F, et al. Open trial of S-adenosylmethionine for treatment of depression. Am J Psychiatry 1984;141:448-50.
    • (1984) Am J Psychiatry , vol.141 , pp. 448-450
    • Lipinski, J.F.1    Cohen, B.M.2    Frankenberg, F.3
  • 43
  • 44
    • 0023877612 scopus 로고
    • An open-label pilot study of oral S-adenosyl-l-methionine in major depression: Interim results
    • Rosenbaum JF, Fava M, Falk WE, et al. An open-label pilot study of oral S-adenosyl-l-methionine in major depression: interim results. Psychopharmacol Bull 1988;24:189-94.
    • (1988) Psychopharmacol Bull , vol.24 , pp. 189-194
    • Rosenbaum, J.F.1    Fava, M.2    Falk, W.E.3
  • 45
    • 0024042418 scopus 로고
    • S-adenosylmethionine in depression. A literature review and preliminary report
    • Janicak PG, Lipinski J, Davis JM, et al. S-adenosylmethionine in depression. A literature review and preliminary report. Ala J Med Sci 1988;25:306-13.
    • (1988) Ala J Med Sci , vol.25 , pp. 306-313
    • Janicak, P.G.1    Lipinski, J.2    Davis, J.M.3
  • 46
    • 0028189416 scopus 로고
    • S-adenosyl-l-methionine (SAMe) as antidepressant: Metaanalysis of clinical studies
    • Bressa GM. S-adenosyl-l-methionine (SAMe) as antidepressant: metaanalysis of clinical studies. Acta Neurol Scand Suppl 1994;154:7-14.
    • (1994) Acta Neurol Scand Suppl , vol.154 , pp. 7-14
    • Bressa, G.M.1
  • 47
    • 0026533906 scopus 로고
    • The pathogenesis of homocysteinemia: Interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine
    • Selhub J, Miller JW. The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine. Am J Clin Nutr 1992;55:131-8.
    • (1992) Am J Clin Nutr , vol.55 , pp. 131-138
    • Selhub, J.1    Miller, J.W.2
  • 48
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease
    • Boushey CJ, Beresford SAA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. JAMA 1995;274:1049-57.
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.A.2    Omenn, G.S.3    Motulsky, A.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.