Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster

PLoS ONE

Volumn 2, Issue 5, 2007, Pages

  Przewloka, Marcin R ^a   Zhang, Wei ^a   Costa, Patricia ^a,c   Archambault, Vincent ^a   D'Avino, Pier Paolo ^a   Lilley, Kathryn S ^a   Laue, Ernest D ^a   McAinsh, Andrew D ^b   Glover, David M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MARIE CURIE RESEARCH INSTITUTE   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA PROTEIN; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; KNL 1 PROTEIN; MIND PROTEIN; MIS12 PROTEIN; NDC80 COMPLEX; NUF2 PROTEIN; SPC105 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BIOINFORMATICS; CENTROMERE; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA MELANOGASTER; INTERPHASE; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PROTEIN ANALYSIS; PROTEOMICS; SEQUENCE ANALYSIS; STRUCTURAL PROTEOMICS; AFFINITY CHROMATOGRAPHY; ANIMAL; CELL CULTURE; CHEMISTRY; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; SEQUENCE HOMOLOGY;

DROSOPHILA MELANOGASTER; EUKARYOTA;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; CHROMATOGRAPHY, AFFINITY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETOCHORES; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PROTEOMICS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 35649025423     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000478     Document Type: Article

References (56)

1. Chan GK, Liu ST, Yen TJ (2005) Kinetochore structure and function. Trends Cell Biol 15: 589-598.
2. Maiato H, DeLuca J, Salmon ED, Earnshaw WC (2004) The dynamic kinetochore-microtubule interface. J Cell Sci 117: 5461-5477.
3. De Wulf P, McAinsh AD, Sorger PK (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17: 2902-2921.
4. McAinsh AD, Tytell JD, Sorger PK (2003) Structure, function, and regulation of budding yeast kinetochores. Annu Rev Cell Dev Biol 19: 519-539.
5. Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A (2006) The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell 127: 983-997.
6. Cheeseman IM, Niessen S, Anderson S, Hyndman F, Yates JR 3rd, et al. (2004) A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev 18: 2255-2268.
7. Desai A, Rybina S, Muller-Reichert T, Shevchenko A, Shevchenko A, et al. (2003) KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans. Genes Dev 17: 2421-2435.
8. McAinsh AD, Meraldi P, Draviam VM, Toso A, Sorger PK (2006) The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation. EMBO J 25: 4033-4049.
9. Liu X, McLeod I, Anderson S, Yates JR 3rd, He X (2005) Molecular analysis of kinetochore architecture in fission yeast. EMBO J 24: 2919-3029.
10. Dawe RK, Henikoff S (2006) Centromeres put epigenetics in the driver's seat. Trends Biochem Sci 31: 662-669.
11. Vos LJ, Famulski JK, Chan GK (2006) How to build a centromere: from centromeric and pericentromeric chromatin to kinetochore assembly. Biochem Cell Biol 84: 619-639.
12. Carroll CW, Straight AF (2006) Centromere formation: from epigenetics to self-assembly. Trends Cell Biol 16: 70-78.
13. Pidoux AL, Allshire RC (2005) The role of heterochromatin in centromere function. Philos Trans R Soc Lond B Biol Sci 360: 569-579.
14. Heit R, Underhill DA, Chan G, Hendzel MJ (2006) Epigenetic regulation of centromere formation and kinetochore function. Biochem Cell Biol 84: 605-618.
15. Morris CA, Moazed D (2007) Centromere assembly and propagation. Cell 128: 647-650.
16. Blower MD, Karpen GH (2001) The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions. Nat Cell Biol 3: 730-739.
17. Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR 3rd, et al. (2006) The human CENP-A centromeric nucleosome-associated complex. Nat Cell Biol 8: 458-469.
18. Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, et al. (2006) The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. Nat Cell Biol 8: 446-457.
19. Furuyama T, Dalal Y, Henikoff S (2006) Chaperone-mediated assembly of centromeric chromatin in vitro. Proc Natl Acad Sci U S A 103: 6172-6177.
20. Fujita Y, Hayashi T, Kiyomitsu T, Toyoda Y, Kokubu A, et al. (2007) Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BPI. Dev Cell 12: 17-30.
21. Meraldi P, McAinsh AD, Rheinbay E, Sorger PK (2006) Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins. Genome Biol 7: R23.
22. Kline SL, Cheeseman IM, Hori T, Fukagawa T, Desai A (2006) The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. J Cell Biol 173: 9-17.
23. DeLuca JG, Dong Y, Hergert P, Strauss J, Hickey JM, et al. (2005) Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites. Mol Biol Cell 16: 519-531.
24. Ciferri C, De Luca J, Monzani S, Ferrari KJ, Ristic D, et al. (2005) Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore. J Biol Chem 280: 29088-29095.
25. Wei RR, Sorger PK, Harrison SC (2005) Molecular organization of the Ndc80 complex, an essential kinetochore component. Proc Natl Acad Sci U S A 102: 5363-5367.
26. Goshima G, Kiyomitsu T, Yoda K, Yanagida M (2003) Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. J Cell Biol 160: 25-39.
27. McCleland ML, Gardner RD, Kallio MJ, Daum JR, Gorbsky GJ, et al. (2003) The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes Dev 17: 101-114.
28. Morrison EE (2007) Action and interactions at microtubule ends. Cell Mol Life Sci 64: 307-317.
29. Karess R (2005) Rod-Zw10-Zwilch: a key player in the spindle checkpoint. Trends Cell Biol 15: 386-392.
30. May KM, Hardwick KG (2006) The spindle checkpoint. J Cell Sci 119: 4139-4142.
31. Rieder CL, Maiato H (2004) Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint. Dev Cell 7: 637-651.
32. Maiato H, Hergert PJ, Moutinho-Pereira S, Dong Y, Vandenbeldt KJ, et al. (2006) The ultrastructure of the kinetochore and kinetochore fiber in Drosophila somatic cells. Chromosoma 115: 469-480.
33. Yucel JK, Marszalek JD, McIntosh JR, Goldstein LS, Cleveland DW, et al. (2000) CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. J Cell Biol 150: 1-11.
34. Glover DM (2005) Polo kinase and progression through M phase in Drosophila: a perspective from the spindle poles. Oncogene 24: 230-237.
35. Arnaud L, Pines J, Nigg EA (1998) GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes. Chromosoma 107: 424-429.
36. Heeger S, Leismann O, Schittenhelm R, Schraidt O, Heidmann S, et al. (2005) Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog. Genes Dev 19: 2041-2053.
37. McCleland ML, Kallio MJ, Barrett-Wilt GA, Kestner CA, Shabanowitz J, et al. (2004) The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Curr Biol 14: 131-137.
38. Ciferri C, De Luca J, Monzani S, Ferrari KJ, Ristic D, et al. (2005) Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore. J Biol Chem 280: 29088-29095.
39. Starr DA, Williams BC, Hays TS, Goldberg ML (1998) ZW10 helps recruit dynactin and dynein to the kinetochore. J Cell Biol 142: 763-774.
40. Rattner JB, Hendzel MJ, Furbee CS, Muller MT, Bazett-Jones DP (1996) Topoisomerase II alpha is associated with the mammalian centromere in a cell cycle- and species-specific manner and is required for proper centromere/kinetochore structure. J Cell Biol 134: 1097-1107.
41. Porter AC, Farr CJ (2004) Topoisomerase II: untangling its contribution at the centromere. Chromosome Res 12: 569-583.
42. Tirnauer JS, Canman JC, Salmon ED, Mitchison TJ (2002) EB1 targets to kinetochores with attached, polymerizing microtubules. Mol Biol Cell 13: 4308-4316.
43. Obuse C, Yang H, Nozaki N, Goto S, Okazaki T, et al. (2004) Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-I) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase. Genes Cells 9: 105-120.
44. Salina D, Enarson P, Rattner JB, Burke B (2003) Nup358 integrates nuclear envelope breakdown with kinetochore assembly. J Cell Biol 162: 991-1001.
45. King JM, Hays TS, Nicklas RB (2000) Dynein is a transient kinetochore component whose binding is regulated by microtubule attachment, not tension. J Cell Biol 13: 739-748.
46. Cortes A, Azorin F (2000) DDPI, a heterochromatin-associated multi-KH-domain protein of Drosophila melanogaster, interacts specifically with centromeric satellite DNA sequences. Mol Cell Biol 20: 3860-3869.
47. Huertas D, Cortes A, Casanova J, Azorin F (2004) Drosophila DDPI, a multi-KH-domain protein, contributes to centromeric silencing and chromosome segregation. Curr Biol 14: 1611-1620.
48. Goshima G, Saitoh S, Yanagida M (1999) Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation. Genes Dev 13: 1664-1677.
49. Liu ST, Rattner JB, Jablonski SA, Yen TJ (2006) Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells. J Cell Biol 175: 41-53.
50. Chen F, Archambault V, Kar A, Lio' P, D'Avino PP, et al. (2007) Multiple protein phosphatases are required for mitosis in Drosophila. Curr Biol 17: 293-303.
51. Puig O, Caspary F, Rigaut G, Rutz B, Bouveret E, et al. (2001) The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods 24: 218-229.
52. Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
53. Lupas A, Vala Dyke M, Stock J (1991) Predicting coiled coils from protein sequences. Science 252: 1162-1164.
54. Worby CA, Simonson-Leff N, Dixon JE (2001) RNA interference of gene expression (RNAi) in cultured Drosophila cells. Sci STKE 95: PL1.
55. Tai CY, Dujardin DL, Faulkner NE, Vallee RB (2002) Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function. J Cell Biol 156: 959-968.
56. Obuse C, Iwasaki O, Kiyomitsu T, Goshima G, Toyoda Y, Yanagida M (2004) A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. Nat Cell Biol 6: 1135-1141.