Structural basis of disease-causing mutations in hepatocyte nuclear factor 1β

Biochemistry

Volumn 46, Issue 43, 2007, Pages 12071-12080

  Lu, Peng ^a   Geun, Bae Rha ^a   Chi, Young In ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CRYSTAL STRUCTURE; DNA; HIERARCHICAL SYSTEMS; MEDICAL PROBLEMS; TRANSCRIPTION;

DISEASE-CAUSING MUTATIONS; DNA BINDING DOMAIN; FUNCTIONAL DISRUPTION; HIERARCHICAL NETWORK;

DISEASES;

HEPATOCYTE NUCLEAR FACTOR 1BETA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIABETES MELLITUS; GENE; GENE MAPPING; GENE MUTATION; HELA CELL; HNF1BETA GENE; HUMAN; HUMAN CELL; KIDNEY DISEASE; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HELA CELLS; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 35648988438     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7010527     Document Type: Article

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