메뉴 건너뛰기




Volumn 32, Issue 10, 2007, Pages 871-882

The proteasome and intracellular redox status: Implications for apoptotic regulation in lens epithelial cells

Author keywords

Apoptosis; GSH GSSG; Lens epithelial cells; Oxidation; Proteasome

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; CHYMOTRYPSIN; DITHIOTHREITOL; ENZYME; GLUTATHIONE; HOE 33342; LACTACYSTIN; PEPTIDYLGLUTAMYL PEPTIDASE; PROTEASOME; REDUCING AGENT; SUPEROXIDE; TRYPSIN; UNCLASSIFIED DRUG;

EID: 35648950047     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.1080/02713680701642327     Document Type: Article
Times cited : (11)

References (45)
  • 1
    • 0030016595 scopus 로고    scopus 로고
    • Structure and functions of the 20s and 26s proteasomes
    • Coux O, et al. Structure and functions of the 20s and 26s proteasomes. Ann Rev Biochem. 1996;65:801-847.
    • (1996) Ann Rev Biochem , vol.65 , pp. 801-847
    • Coux, O.1
  • 2
    • 18244396127 scopus 로고    scopus 로고
    • Subcellular redistribution of components of the ubiquitin-proteasome pathway during lens differentiation and maturation
    • Girao H, et al. Subcellular redistribution of components of the ubiquitin-proteasome pathway during lens differentiation and maturation. IOVS. 2005;46(4):1386-1392.
    • (2005) IOVS , vol.46 , Issue.4 , pp. 1386-1392
    • Girao, H.1
  • 3
    • 33745675537 scopus 로고    scopus 로고
    • Ubiquitin-proteasome pathway function is required for lens cell proliferation and differentiation
    • Guo W, et al. Ubiquitin-proteasome pathway function is required for lens cell proliferation and differentiation. IOVS. 2006;47(6):2569-2575.
    • (2006) IOVS , vol.47 , Issue.6 , pp. 2569-2575
    • Guo, W.1
  • 4
    • 0023600801 scopus 로고
    • Protein oxidation and loss of protease activity may lead to cataract formation in the aged lens
    • Taylor A, Davies KJA. Protein oxidation and loss of protease activity may lead to cataract formation in the aged lens. Free Radic Biol Med. 1987;3:371-377.
    • (1987) Free Radic Biol Med , vol.3 , pp. 371-377
    • Taylor, A.1    Davies, K.J.A.2
  • 5
    • 0023813177 scopus 로고
    • Age-related increase in concentration and aggregation of degraded polypeptides in human lenses
    • Srivastava P. Age-related increase in concentration and aggregation of degraded polypeptides in human lenses. Exp Eye Res. 1988;47:525-543.
    • (1988) Exp Eye Res , vol.47 , pp. 525-543
    • Srivastava, P.1
  • 6
    • 0033197542 scopus 로고    scopus 로고
    • Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown
    • Kisselev AF, et al. Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown. Mol Cell. 1999;4(3):395-402.
    • (1999) Mol Cell , vol.4 , Issue.3 , pp. 395-402
    • Kisselev, A.F.1
  • 7
    • 0141704418 scopus 로고    scopus 로고
    • The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites
    • Kisselev AF, et al. The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. J Biol Chem. 2003;278(38):35869-35877.
    • (2003) J Biol Chem , vol.278 , Issue.38 , pp. 35869-35877
    • Kisselev, A.F.1
  • 8
    • 0021928777 scopus 로고
    • Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases
    • Rivett AJ. Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases. J Biol Chem. 1985;260(1):300-305.
    • (1985) J Biol Chem , vol.260 , Issue.1 , pp. 300-305
    • Rivett, A.J.1
  • 9
    • 0025262177 scopus 로고
    • Lens proteasome shows enhanced rates of degradation of hydroxyl radical modified alpha-crystallin
    • Murakami K, et al. Lens proteasome shows enhanced rates of degradation of hydroxyl radical modified alpha-crystallin. Free Radic Biol Med. 1990;8(3):217-222.
    • (1990) Free Radic Biol Med , vol.8 , Issue.3 , pp. 217-222
    • Murakami, K.1
  • 10
    • 4043127599 scopus 로고    scopus 로고
    • Crystallins in water soluble-high molecular weight protein fractions and water insoluble protein fractions in aging and cataractous human lenses
    • Harrington V, et al. Crystallins in water soluble-high molecular weight protein fractions and water insoluble protein fractions in aging and cataractous human lenses. Mol Vis. 2004;10:476-489.
    • (2004) Mol Vis , vol.10 , pp. 476-489
    • Harrington, V.1
  • 11
    • 0042198801 scopus 로고    scopus 로고
    • Redox regulation in the lens
    • Lou MF. Redox regulation in the lens. Prog Retin Eye Res. 2003;22(5):657-682.
    • (2003) Prog Retin Eye Res , vol.22 , Issue.5 , pp. 657-682
    • Lou, M.F.1
  • 12
    • 0033230043 scopus 로고    scopus 로고
    • Glutathione and its role in cellular functions
    • Sies H. Glutathione and its role in cellular functions. Free Radic Biol Med. 1999;27(9-10):916-921.
    • (1999) Free Radic Biol Med , vol.27 , Issue.9-10 , pp. 916-921
    • Sies, H.1
  • 13
    • 0033231162 scopus 로고    scopus 로고
    • Biologic and pharmacologic regulation of mammalian glutathione synthesis
    • Griffith OW. Biologic and pharmacologic regulation of mammalian glutathione synthesis. Free Radic Biol Med. 1999;27(9-10):922-935.
    • (1999) Free Radic Biol Med , vol.27 , Issue.9-10 , pp. 922-935
    • Griffith, O.W.1
  • 14
    • 1542376929 scopus 로고    scopus 로고
    • Glutathione metabolism and its implications for health
    • Wu G, et al. Glutathione metabolism and its implications for health. J Nutr. 2004;134(3):489-492.
    • (2004) J Nutr , vol.134 , Issue.3 , pp. 489-492
    • Wu, G.1
  • 15
    • 0142089055 scopus 로고    scopus 로고
    • Oxidative signaling and glutathione synthesis
    • Forman HJ, Dickinson DA. Oxidative signaling and glutathione synthesis. Biofactors. 2003;17(1-4):1-12.
    • (2003) Biofactors , vol.17 , Issue.1-4 , pp. 1-12
    • Forman, H.J.1    Dickinson, D.A.2
  • 16
    • 0038635950 scopus 로고    scopus 로고
    • Cytoprotection against oxidative stress and the regulation of glutathione synthesis
    • Dickinson DA, et al. Cytoprotection against oxidative stress and the regulation of glutathione synthesis. Biol Chem. 2003;384(4):527-537.
    • (2003) Biol Chem , vol.384 , Issue.4 , pp. 527-537
    • Dickinson, D.A.1
  • 17
    • 0037728958 scopus 로고    scopus 로고
    • Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism
    • Demasi M, Davies KJ. Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism. FEBS Lett. 2003;542(1-3):89-94.
    • (2003) FEBS Lett , vol.542 , Issue.1-3 , pp. 89-94
    • Demasi, M.1    Davies, K.J.2
  • 18
    • 27244462417 scopus 로고    scopus 로고
    • Glutathiolation of the proteasome is enhanced by proteolytic inhibitors
    • Demasi M, et al. Glutathiolation of the proteasome is enhanced by proteolytic inhibitors. Arch Biochem Biophys. 2001;389(2):254-263.
    • (2001) Arch Biochem Biophys , vol.389 , Issue.2 , pp. 254-263
    • Demasi, M.1
  • 19
    • 33748105296 scopus 로고    scopus 로고
    • Glutathiolation enhances the degradation of gammac-crystallin in lens and reticulocyte lysates, partially via the ubiquitin-proteasome pathway
    • Zetterberg M, et al. Glutathiolation enhances the degradation of gammac-crystallin in lens and reticulocyte lysates, partially via the ubiquitin-proteasome pathway. IOVS. 2006;47(8):3467-3473.
    • (2006) IOVS , vol.47 , Issue.8 , pp. 3467-3473
    • Zetterberg, M.1
  • 20
    • 27344460622 scopus 로고    scopus 로고
    • Potential protective effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells and intact mouse lenses in culture
    • Petersen A, et al. Potential protective effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells and intact mouse lenses in culture. Ophthalmic Res. 2005;37(6):318-327.
    • (2005) Ophthalmic Res , vol.37 , Issue.6 , pp. 318-327
    • Petersen, A.1
  • 21
    • 0032144578 scopus 로고    scopus 로고
    • Proteolytic cleavage of n-succ-leu-leu-val-tyramc by the proteasome in lens epithelium fromclear and cataractous human lenses
    • Andersson M, et al. Proteolytic cleavage of n-succ-leu-leu-val-tyramc by the proteasome in lens epithelium fromclear and cataractous human lenses. Exp Eye Res. 1998;67(2):231-236.
    • (1998) Exp Eye Res , vol.67 , Issue.2 , pp. 231-236
    • Andersson, M.1
  • 22
    • 0033956489 scopus 로고    scopus 로고
    • Estimation of submicrogram quantities of protein using the dye eosin Y
    • Waheed AA and Gupta PD. Estimation of submicrogram quantities of protein using the dye eosin Y. J Biochem Biophys Methods. 2000;42(3):125-132.
    • (2000) J Biochem Biophys Methods , vol.42 , Issue.3 , pp. 125-132
    • Waheed, A.A.1    Gupta, P.D.2
  • 23
    • 1542297664 scopus 로고    scopus 로고
    • A new model for assessing proteolysis in the intact mouse lens in organ culture
    • Petersen A, et al. A new model for assessing proteolysis in the intact mouse lens in organ culture. Ophthalmic Res. 2004;36(1):25-30.
    • (2004) Ophthalmic Res , vol.36 , Issue.1 , pp. 25-30
    • Petersen, A.1
  • 24
    • 0035577283 scopus 로고    scopus 로고
    • Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane
    • Keelan J, et al. Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane. J Neurosci Res. 2001;66(5):873-884.
    • (2001) J Neurosci Res , vol.66 , Issue.5 , pp. 873-884
    • Keelan, J.1
  • 25
    • 0030447280 scopus 로고    scopus 로고
    • Human senescence
    • Kirkwood TB. Human senescence. Bioessays. 1996;18(12):1009-1016.
    • (1996) Bioessays , vol.18 , Issue.12 , pp. 1009-1016
    • Kirkwood, T.B.1
  • 26
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 1996;273(5271):59-63.
    • (1996) Science , vol.273 , Issue.5271 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 27
    • 0031081488 scopus 로고    scopus 로고
    • Deleterious network hypothesis of aging
    • Ying W. Deleterious network hypothesis of aging. Med Hypotheses. 1997;48(2):143-148.
    • (1997) Med Hypotheses , vol.48 , Issue.2 , pp. 143-148
    • Ying, W.1
  • 28
    • 0002711549 scopus 로고
    • The lens and oxidative stress
    • H Siesed, Düsseldorf: Academic Press;
    • Spector A. The lens and oxidative stress. In: H Siesed. Oxidative Stress: Oxidants and Antioxidants. Düsseldorf: Academic Press; 1991:529-558.
    • (1991) Oxidative Stress: Oxidants and Antioxidants , pp. 529-558
    • Spector, A.1
  • 29
    • 0022444186 scopus 로고
    • Lipid peroxidation in cataract of the human
    • Bhuyan KC, et al. Lipid peroxidation in cataract of the human. Life Sci. 1986;38:1463-1471.
    • (1986) Life Sci , vol.38 , pp. 1463-1471
    • Bhuyan, K.C.1
  • 30
    • 0019843761 scopus 로고
    • Hydrogen peroxide and human cataract
    • Spector A, Garner WH. Hydrogen peroxide and human cataract. Exp Eye Res. 1981;33(6):673-681.
    • (1981) Exp Eye Res , vol.33 , Issue.6 , pp. 673-681
    • Spector, A.1    Garner, W.H.2
  • 31
    • 0030823263 scopus 로고    scopus 로고
    • Long-term vitamin c supplement use and prevalence of early age-related lens opacities
    • Jacques PF, et al. Long-term vitamin c supplement use and prevalence of early age-related lens opacities. Am J Clin Nutr. 1997;66(4):911-916.
    • (1997) Am J Clin Nutr , vol.66 , Issue.4 , pp. 911-916
    • Jacques, P.F.1
  • 32
    • 0031968378 scopus 로고    scopus 로고
    • Antioxidant vitamins and nuclear opacities: The longitudinal study of cataract
    • Leske MC, et al. Antioxidant vitamins and nuclear opacities: The longitudinal study of cataract. Ophthalmology. 1998;105(5):831-836.
    • (1998) Ophthalmology , vol.105 , Issue.5 , pp. 831-836
    • Leske, M.C.1
  • 33
    • 18044388716 scopus 로고    scopus 로고
    • Age-related nuclear cataract-oxidation is the key
    • Truscott RJ. Age-related nuclear cataract-oxidation is the key. Exp Eye Res. 2005;80(5):709-725.
    • (2005) Exp Eye Res , vol.80 , Issue.5 , pp. 709-725
    • Truscott, R.J.1
  • 34
    • 0034012636 scopus 로고    scopus 로고
    • Glutathione: A vital lens antioxidant
    • Giblin FJ. Glutathione: a vital lens antioxidant. J Ocul Pharmacol Ther. 2000;16(2):121-135.
    • (2000) J Ocul Pharmacol Ther , vol.16 , Issue.2 , pp. 121-135
    • Giblin, F.J.1
  • 35
    • 0022469901 scopus 로고
    • Near-total glutathione depletion and age-specific cataracts induced by buthionine sulfoximine in mice
    • Calvin HI, et al. Near-total glutathione depletion and age-specific cataracts induced by buthionine sulfoximine in mice. Science. 1986;233(4763):553-555.
    • (1986) Science , vol.233 , Issue.4763 , pp. 553-555
    • Calvin, H.I.1
  • 36
    • 0021251947 scopus 로고
    • State of sulfhydryl in selenite cataract
    • David LL, Shearer TR. State of sulfhydryl in selenite cataract. Toxicol Appl Pharmacol. 1984;74(1):109-115.
    • (1984) Toxicol Appl Pharmacol , vol.74 , Issue.1 , pp. 109-115
    • David, L.L.1    Shearer, T.R.2
  • 37
    • 0024314190 scopus 로고
    • Disulfide cross-linking of urea-insoluble proteins in rabbit lenses treated with hyperbaric oxygen
    • Padgaonkar V, et al. Disulfide cross-linking of urea-insoluble proteins in rabbit lenses treated with hyperbaric oxygen. Exp Eye Res. 1989;49(5):887-899.
    • (1989) Exp Eye Res , vol.49 , Issue.5 , pp. 887-899
    • Padgaonkar, V.1
  • 38
    • 0027087293 scopus 로고
    • Protein-thiol mixed disulfides in humanlens
    • Lou MF, Dickerson JE, Jr. Protein-thiol mixed disulfides in humanlens. Exp Eye Res. 1992;55(6):889-896.
    • (1992) Exp Eye Res , vol.55 , Issue.6 , pp. 889-896
    • Lou, M.F.1    Dickerson Jr., J.E.2
  • 39
    • 0024459737 scopus 로고
    • Effect of opacification and pigmentation on human lens protein thiol/disulfide and solubility
    • Lou MF, et al. Effect of opacification and pigmentation on human lens protein thiol/disulfide and solubility. Curr Eye Res. 1989;8(9):883-890.
    • (1989) Curr Eye Res , vol.8 , Issue.9 , pp. 883-890
    • Lou, M.F.1
  • 40
    • 0030724889 scopus 로고    scopus 로고
    • Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress
    • Jahngen-Hodge J, et al. Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress. J Biol Chem. 1997;272(45):28218- 28226.
    • (1997) J Biol Chem , vol.272 , Issue.45 , pp. 28218-28226
    • Jahngen-Hodge, J.1
  • 41
    • 0031893232 scopus 로고    scopus 로고
    • Redox regulation of ubiquitin-conjugating enzymes: Mechanistic insights using the thiol-specific oxidant diamide
    • Obin M, et al. Redox regulation of ubiquitin-conjugating enzymes: Mechanistic insights using the thiol-specific oxidant diamide. FASEB J. 1998;12(7):561-569.
    • (1998) FASEB J , vol.12 , Issue.7 , pp. 561-569
    • Obin, M.1
  • 42
    • 35649006914 scopus 로고    scopus 로고
    • Intracellular effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells in culture
    • Accepted 12 July
    • Petersen A, et al. Intracellular effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells in culture. Ophthalmic Res. Accepted 12 July 2007.
    • (2007) Ophthalmic Res
    • Petersen, A.1
  • 43
    • 0032513215 scopus 로고    scopus 로고
    • Proteasome inhibitors activate stress kinases and induce hsp72. Diverse effects on apoptosis
    • Meriin AB, et al. Proteasome inhibitors activate stress kinases and induce hsp72. Diverse effects on apoptosis. J Biol Chem. 1998;273(11):6373-6379.
    • (1998) J Biol Chem , vol.273 , Issue.11 , pp. 6373-6379
    • Meriin, A.B.1
  • 44
    • 0033863365 scopus 로고    scopus 로고
    • Caspase and proteasome activity during staurosporin-induced apoptosis in lens epithelial cells
    • Andersson M, et al. Caspase and proteasome activity during staurosporin-induced apoptosis in lens epithelial cells. IOVS. 2000;41(9):2623-2632.
    • (2000) IOVS , vol.41 , Issue.9 , pp. 2623-2632
    • Andersson, M.1
  • 45
    • 0347358034 scopus 로고    scopus 로고
    • Interferon-gamma induces apoptosis of lens alphatn4-1 cells and proteasome inhibition has an antiapoptotic effect
    • Awasthi N Wagner BJ. Interferon-gamma induces apoptosis of lens alphatn4-1 cells and proteasome inhibition has an antiapoptotic effect. IOVS. 2004;45(1):222-229.
    • (2004) IOVS , vol.45 , Issue.1 , pp. 222-229
    • Awasthi, N.1    Wagner, B.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.