Interferon-γ Induces Apoptosis of Lens αTN4-1 Cells and Proteasome Inhibition Has an Antiapoptotic Effect

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 1, 2004, Pages 222-229

  Awasthi, Niranjan ^a   Wagner, B J ^a,b  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b INSTITUTE OF OPHTHALMOLOGY AND VISUAL SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE; CASPASE 3; CASPASE 8; DNA FRAGMENT; FLUORESCEIN ISOTHIOCYANATE; GAMMA INTERFERON; IMMUNOPROTEASOME; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTACYSTIN; LIPOCORTIN 5; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROPIDIUM IODIDE; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; STAT1 PROTEIN; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIAPOPTOTIC ACTIVITY; APOPTOSIS; ARTICLE; CATARACT; CELL LINE; CELL PROTECTION; CELL STRUCTURE; COLORIMETRY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; LENS EPITHELIUM; LENS EPITHELIUM ALPHATN4 1 CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; TISSUE DIFFERENTIATION; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; ANNEXIN A5; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE; CELL SURVIVAL; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; CYTOPROTECTION; DNA-BINDING PROTEINS; EPITHELIAL CELLS; INTERFERON REGULATORY FACTOR-1; INTERFERON REGULATORY FACTORS; INTERFERON-GAMMA, RECOMBINANT; LENS, CRYSTALLINE; LEUPEPTINS; MICE; MULTIENZYME COMPLEXES; PHOSPHOPROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; UP-REGULATION;

EID: 0347358034     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.03-0571     Document Type: Article

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