-
1
-
-
0030614893
-
2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
-
2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med, 1997; 3: 177-82
-
(1997)
Nat Med
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Dellian, M.3
Jain, R.K.4
-
2
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
Vaupel P, Kallinowski F, Okunieff P: Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res, 1989; 49: 6449-65
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
3
-
-
8544271638
-
Hypoxia-inducible factors and hypoxic cell death in tumour physiology
-
Bacon AL, Harris AL: Hypoxia-inducible factors and hypoxic cell death in tumour physiology. Ann Med, 2004; 36: 530-39
-
(2004)
Ann Med
, vol.36
, pp. 530-539
-
-
Bacon, A.L.1
Harris, A.L.2
-
4
-
-
33947164399
-
Effect of hypoxia on the tumor phenotype: The neuroblastoma and breast cancer models
-
Holmquist L, Lofstedt T, Pahlman S: Effect of hypoxia on the tumor phenotype: the neuroblastoma and breast cancer models. Adv Exp Med Biol, 2006; 587: 179-93
-
(2006)
Adv Exp Med Biol
, vol.587
, pp. 179-193
-
-
Holmquist, L.1
Lofstedt, T.2
Pahlman, S.3
-
5
-
-
33645331832
-
Oxygenated and reoxygenated tumors show better local control in radiation therapy for cervical cancer
-
Suzuki Y, Nakano T, Ohno T et al: Oxygenated and reoxygenated tumors show better local control in radiation therapy for cervical cancer. Int J Gynecol Cancer, 2006; 16: 306-11
-
(2006)
Int J Gynecol Cancer
, vol.16
, pp. 306-311
-
-
Suzuki, Y.1
Nakano, T.2
Ohno, T.3
-
6
-
-
0036918282
-
Impact of tumor hypoxia and anemia on radiation therapy outcomes
-
Harrison LB, Chadha M, Hill RJ et al: Impact of tumor hypoxia and anemia on radiation therapy outcomes. Oncologist, 2002; 7: 492-508
-
(2002)
Oncologist
, vol.7
, pp. 492-508
-
-
Harrison, L.B.1
Chadha, M.2
Hill, R.J.3
-
7
-
-
0028632781
-
Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors
-
Overgaard J: Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors. Oncol Res, 1994; 6: 509-18
-
(1994)
Oncol Res
, vol.6
, pp. 509-518
-
-
Overgaard, J.1
-
8
-
-
35549007324
-
The genomic response of tumour cells to hypoxia and reoxygenation: Differential activation of transcription factors AP-1 and NF-kB
-
Rupec RA: The genomic response of tumour cells to hypoxia and reoxygenation: differential activation of transcription factors AP-1 and NF-kB. Med Sci Monit, 1996; 2: 6-13
-
(1996)
Med Sci Monit
, vol.2
, pp. 6-13
-
-
Rupec, R.A.1
-
9
-
-
24944456241
-
Hyperbaric oxygen and malignancies: A potential role in radiotherapy, chemotherapy, tumor surgery and phototherapy
-
Al-Waili NS, Butler GJ, Beale J et al: Hyperbaric oxygen and malignancies: a potential role in radiotherapy, chemotherapy, tumor surgery and phototherapy. Med Sci Monit, 2005; 11(9): RA279-89
-
(2005)
Med Sci Monit
, vol.11
, Issue.9
-
-
Al-Waili, N.S.1
Butler, G.J.2
Beale, J.3
-
10
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
Hockel M, Vaupel P: Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst, 2001; 93: 266-76
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 266-276
-
-
Hockel, M.1
Vaupel, P.2
-
11
-
-
16244399521
-
Tumor oxygenation status as a prognostic marker
-
Menon C, Fraker DL: Tumor oxygenation status as a prognostic marker. Cancer Lett, 2005; 221: 225-35
-
(2005)
Cancer Lett
, vol.221
, pp. 225-235
-
-
Menon, C.1
Fraker, D.L.2
-
12
-
-
10644270846
-
Tumor hypoxia: Causative factors, compensatory mechanisms, and cellular response
-
Vaupel P, Harrison L: Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response. Oncologist, 2004; 9(Suppl.5): 4-9
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL.5
, pp. 4-9
-
-
Vaupel, P.1
Harrison, L.2
-
13
-
-
4644283094
-
Assessment of tumor oxygenation by electron paramagnetic resonance: Principles and applications
-
Gallez B, Baudelet C, Jordan BF: Assessment of tumor oxygenation by electron paramagnetic resonance: principles and applications. NMR Biomed, 2004; 17: 240-62
-
(2004)
NMR Biomed
, vol.17
, pp. 240-262
-
-
Gallez, B.1
Baudelet, C.2
Jordan, B.F.3
-
14
-
-
33646190926
-
PET and PET/CT studies of tumor tissue oxygenation. Q
-
Krause BJ, Beck R, Souvatzoglou M, Piert M: PET and PET/CT studies of tumor tissue oxygenation. Q J Nucl Med Mol Imaging, 2006; 50: 28-43
-
(2006)
J Nucl Med Mol Imaging
, vol.50
, pp. 28-43
-
-
Krause, B.J.1
Beck, R.2
Souvatzoglou, M.3
Piert, M.4
-
15
-
-
33947100334
-
A Quantitative review of the use of FDG-PET in the axillary staging of breast cancer
-
Sloka JS, Hollett PD, Mathews M: A Quantitative review of the use of FDG-PET in the axillary staging of breast cancer. Med Sci Monit, 2007; 13(3): RA37-46
-
(2007)
Med Sci Monit
, vol.13
, Issue.3
-
-
Sloka, J.S.1
Hollett, P.D.2
Mathews, M.3
-
16
-
-
34548155736
-
Determination of tumour hypoxia with the PET tracer [(18)F]EF3: Improvement of the tumour-to-background ratio in a mouse tumour model
-
Mar 3; [Epub ahead of print
-
Christian N, Bol A, De Bast M et al: Determination of tumour hypoxia with the PET tracer [(18)F]EF3: improvement of the tumour-to-background ratio in a mouse tumour model. Eur J Nucl Med Mol Imaging, 2007 Mar 3; [Epub ahead of print]
-
(2007)
Eur J Nucl Med Mol Imaging
-
-
Christian, N.1
Bol, A.2
De Bast, M.3
-
17
-
-
34247890108
-
The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography
-
Matsumoto K, Szajek L, Krishna MC et al: The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography. Int J Oncol, 2007; 30: 873-81
-
(2007)
Int J Oncol
, vol.30
, pp. 873-881
-
-
Matsumoto, K.1
Szajek, L.2
Krishna, M.C.3
-
18
-
-
33750738550
-
Novel noninvasive probes for measuring tumor-hypoxia by 19F-magnetic resonance spectroscopy (19F-MRS). Studies in the SCCVII/C3H murine model
-
Papadopoulou MV, Pouremad R, Bloomer WD, Wyrwicz A: Novel noninvasive probes for measuring tumor-hypoxia by 19F-magnetic resonance spectroscopy (19F-MRS). Studies in the SCCVII/C3H murine model. Anticancer Res, 2006; 26: 3259-63
-
(2006)
Anticancer Res
, vol.26
, pp. 3259-3263
-
-
Papadopoulou, M.V.1
Pouremad, R.2
Bloomer, W.D.3
Wyrwicz, A.4
-
19
-
-
3142552508
-
Measurement of tumor hypoxia using single-cell methods
-
Olive PL, Aquino-Parsons C: Measurement of tumor hypoxia using single-cell methods. Semin Radiat Oncol, 2004; 14: 241-48
-
(2004)
Semin Radiat Oncol
, vol.14
, pp. 241-248
-
-
Olive, P.L.1
Aquino-Parsons, C.2
-
20
-
-
0031981258
-
Measuring hypoxia and predicting tumor radioresistance with nuclear medicine assays
-
Chapman JD, Engelhardt EL, Stobbe CC et al: Measuring hypoxia and predicting tumor radioresistance with nuclear medicine assays. Radiother Oncol, 1998; 46: 229-37
-
(1998)
Radiother Oncol
, vol.46
, pp. 229-237
-
-
Chapman, J.D.1
Engelhardt, E.L.2
Stobbe, C.C.3
-
21
-
-
23844485492
-
Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors
-
Sobhanifar S, Aquino-Parsons C, Stanbridge EJ, Olive P: Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors. Cancer Res, 2005; 65: 7259-66
-
(2005)
Cancer Res
, vol.65
, pp. 7259-7266
-
-
Sobhanifar, S.1
Aquino-Parsons, C.2
Stanbridge, E.J.3
Olive, P.4
-
22
-
-
0031656984
-
Use of 2-nitroimidazoles as bioreductive markers for tumour hypoxia
-
Hodgkiss RJ: Use of 2-nitroimidazoles as bioreductive markers for tumour hypoxia. Anticancer Drug Des, 1998; 13: 687-702
-
(1998)
Anticancer Drug Des
, vol.13
, pp. 687-702
-
-
Hodgkiss, R.J.1
-
23
-
-
18244431401
-
Expression of carbonic anhydrase IX in human pancreatic cancer
-
Juhasz M, Chen J, Lendeckel U et al: Expression of carbonic anhydrase IX in human pancreatic cancer. Aliment Pharmacol Ther, 2003; 18: 837-46
-
(2003)
Aliment Pharmacol Ther
, vol.18
, pp. 837-846
-
-
Juhasz, M.1
Chen, J.2
Lendeckel, U.3
-
24
-
-
33751162608
-
Immunohistochemical detection of osteopontin in advanced head-and-neck cancer: Prognostic role and correlation with oxygen electrode measurements, hypoxia-inducible-factor-1alpha-related markers, and hemoglobin levels
-
Bache M, Reddemann R, Said HM et al: Immunohistochemical detection of osteopontin in advanced head-and-neck cancer: prognostic role and correlation with oxygen electrode measurements, hypoxia-inducible-factor-1alpha-related markers, and hemoglobin levels. Int J Radiat Oncol Biol Phys, 2006; 66: 1481-87
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.66
, pp. 1481-1487
-
-
Bache, M.1
Reddemann, R.2
Said, H.M.3
-
25
-
-
4944244259
-
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
-
Murdoch C, Giannoudis A, Lewis CE: Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood, 2004; 104: 2224-34
-
(2004)
Blood
, vol.104
, pp. 2224-2234
-
-
Murdoch, C.1
Giannoudis, A.2
Lewis, C.E.3
-
26
-
-
0038827528
-
Inhibitory effect of high molecular weight water-soluble chitosan on hypoxia-induced inflammatory cytokine production
-
Seo SB, Jeong HJ, Chung HS et al: Inhibitory effect of high molecular weight water-soluble chitosan on hypoxia-induced inflammatory cytokine production. Biol Pharm Bull, 2003; 26: 717-21
-
(2003)
Biol Pharm Bull
, vol.26
, pp. 717-721
-
-
Seo, S.B.1
Jeong, H.J.2
Chung, H.S.3
-
27
-
-
17744366566
-
Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: A possible promotion mechanism of carcinogenesis
-
Garayoa M, Martinez A, Lee S et al: Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis. Mol Endocrinol, 2000; 14: 848-62
-
(2000)
Mol Endocrinol
, vol.14
, pp. 848-862
-
-
Garayoa, M.1
Martinez, A.2
Lee, S.3
-
28
-
-
1842868935
-
Molecular responses to hypoxia in tumor cells
-
Kunz M, Ibrahim SM: Molecular responses to hypoxia in tumor cells. Mol Cancer, 2003; 2: 23-35
-
(2003)
Mol Cancer
, vol.2
, pp. 23-35
-
-
Kunz, M.1
Ibrahim, S.M.2
-
29
-
-
0032749463
-
Hypoxia-induced activation of HIF-1: Role of HIF-1alpha-Hsp90 interaction
-
Minet E, Mottet D, Michel G et al: Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction. FEBS Lett, 1999; 460: 251-56
-
(1999)
FEBS Lett
, vol.460
, pp. 251-256
-
-
Minet, E.1
Mottet, D.2
Michel, G.3
-
30
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
Semenza GL: Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology (Bethesda), 2004; 19: 176-82
-
(2004)
Physiology (Bethesda)
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
31
-
-
33645730274
-
Regulation of BNIP3 in normal and cancer cells
-
Lee H, Paik SG: Regulation of BNIP3 in normal and cancer cells. Mol Cells, 2006; 21: 1-6
-
(2006)
Mol Cells
, vol.21
, pp. 1-6
-
-
Lee, H.1
Paik, S.G.2
-
32
-
-
0034050050
-
Loss of PTEN facilitates HIF-1-mediated gene expression
-
Zundel W, Schindler C, Haas-Kogan D et al: Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev, 2000; 14: 391-96
-
(2000)
Genes Dev
, vol.14
, pp. 391-396
-
-
Zundel, W.1
Schindler, C.2
Haas-Kogan, D.3
-
33
-
-
0037404443
-
Genetic models in applied physiology: Invited review: effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest
-
Douglas RM, Haddad GG: Genetic models in applied physiology: invited review: effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest. J Appl Physiol, 2003; 94: 2068-83
-
(2003)
J Appl Physiol
, vol.94
, pp. 2068-2083
-
-
Douglas, R.M.1
Haddad, G.G.2
-
34
-
-
0036206130
-
Protean PTEN: Form and function
-
Waite KA, Eng C: Protean PTEN: form and function. Am J Hum Genet, 2002; 70: 829-44
-
(2002)
Am J Hum Genet
, vol.70
, pp. 829-844
-
-
Waite, K.A.1
Eng, C.2
-
35
-
-
16644363476
-
HIF-1 and p53: Communication of transcription factors under hypoxia
-
Schmid T, Zhou J, Brune B: HIF-1 and p53: communication of transcription factors under hypoxia. J Cell Mol Med, 2004; 8: 423-31
-
(2004)
J Cell Mol Med
, vol.8
, pp. 423-431
-
-
Schmid, T.1
Zhou, J.2
Brune, B.3
-
36
-
-
4444311880
-
Hypoxia inducible factor-1alpha as a cancer drug target
-
Powis G, Kirkpatrick L: Hypoxia inducible factor-1alpha as a cancer drug target. Mol Cancer Ther, 2004; 3: 647-54
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 647-654
-
-
Powis, G.1
Kirkpatrick, L.2
-
37
-
-
0030512608
-
Transgenic mouse models of tumour angiogenesis: The angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models
-
Hanahan D, Christofori G, Naik P, Arbeit J: Transgenic mouse models of tumour angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models. Eur J Cancer, 1996; 32A: 2386-93
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 2386-2393
-
-
Hanahan, D.1
Christofori, G.2
Naik, P.3
Arbeit, J.4
-
38
-
-
0029842459
-
Oxygen sensing and molecular adaptation to hypoxia
-
Bunn HF, Poyton RO: Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev, 1996; 76: 839-85
-
(1996)
Physiol Rev
, vol.76
, pp. 839-885
-
-
Bunn, H.F.1
Poyton, R.O.2
-
39
-
-
24044437159
-
Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): Possible link between angiogenesis and immune tolerance
-
Strauss L, Volland D, Kunkel M, Reichert TE: Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): possible link between angiogenesis and immune tolerance. Med Sci Monit, 2005; 11(8): BR280-92
-
(2005)
Med Sci Monit
, vol.11
, Issue.8
-
-
Strauss, L.1
Volland, D.2
Kunkel, M.3
Reichert, T.E.4
-
40
-
-
3042855669
-
Expression of vascular endothelial growth factor-A and vascular endothelial growth factor-C as prognostic factors for non-small cell lung cancer
-
Nakashima T, Huang CL, Liu D et al: Expression of vascular endothelial growth factor-A and vascular endothelial growth factor-C as prognostic factors for non-small cell lung cancer. Med Sci Monit, 2004; 10(6): BR157-65
-
(2004)
Med Sci Monit
, vol.10
, Issue.6
-
-
Nakashima, T.1
Huang, C.L.2
Liu, D.3
-
41
-
-
0032568448
-
Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha
-
An WG, Kanekal M, Simon MC et al: Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha. Nature, 1998; 392: 405-8
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
-
42
-
-
0032907687
-
Vascular endothelial growth factor (VEGF) and its receptors
-
Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z: Vascular endothelial growth factor (VEGF) and its receptors. Faseb J, 1999; 13: 9-22
-
(1999)
Faseb J
, vol.13
, pp. 9-22
-
-
Neufeld, G.1
Cohen, T.2
Gengrinovitch, S.3
Poltorak, Z.4
-
43
-
-
0037872699
-
Angiogenesis in ischemic and neoplastic disorders
-
Semenza GL: Angiogenesis in ischemic and neoplastic disorders. Annu Rev Med, 2003; 54: 17-28
-
(2003)
Annu Rev Med
, vol.54
, pp. 17-28
-
-
Semenza, G.L.1
-
44
-
-
0029849637
-
In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor/vascular endothelial growth factor
-
Cao Y, Linden P, Shima D et al: In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor/vascular endothelial growth factor. J Clin Invest, 1996; 98: 2507-11
-
(1996)
J Clin Invest
, vol.98
, pp. 2507-2511
-
-
Cao, Y.1
Linden, P.2
Shima, D.3
-
45
-
-
0028843411
-
Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents
-
Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ: Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. Am J Physiol, 1995; 268: C1362-68
-
(1995)
Am J Physiol
, vol.268
-
-
Gleadle, J.M.1
Ebert, B.L.2
Firth, J.D.3
Ratcliffe, P.J.4
-
46
-
-
2942615346
-
Influence of hypoxia and neoangiogenesis on the growth of pancreatic cancer
-
Duffy JP, Eibl G, Reber HA, Hines OJ: Influence of hypoxia and neoangiogenesis on the growth of pancreatic cancer. Mol Cancer, 2003; 2: 12-21
-
(2003)
Mol Cancer
, vol.2
, pp. 12-21
-
-
Duffy, J.P.1
Eibl, G.2
Reber, H.A.3
Hines, O.J.4
-
47
-
-
33747128652
-
Hypoxia and angiogenesis in pancreatic cancer
-
Garcea G, Doucas H, Steward WP et al: Hypoxia and angiogenesis in pancreatic cancer. ANZ J Surg, 2006; 76: 830-42
-
(2006)
ANZ J Surg
, vol.76
, pp. 830-842
-
-
Garcea, G.1
Doucas, H.2
Steward, W.P.3
-
48
-
-
24044461733
-
Macrophage responses to hypoxia: Implications for tumor progression and anti-cancer therapies
-
Lewis C, Murdoch C: Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies. Am J Pathol, 2005; 167: 627-35
-
(2005)
Am J Pathol
, vol.167
, pp. 627-635
-
-
Lewis, C.1
Murdoch, C.2
|