-
1
-
-
0020505557
-
In vivo effects of DL-α-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei
-
Bacchi CJ, Garofalo J, Mockenhaupt D, McCann PP, Diekma KA, Pegg AA, Nathan HC, Mullaney EA, Chunosoff LT, Sjoerdsma A and Hutner SH, In vivo effects of DL-α-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei. Mol Biochem Parasitol 7: 209-225, 1983.
-
(1983)
Mol Biochem Parasitol
, vol.7
, pp. 209-225
-
-
Bacchi, C.J.1
Garofalo, J.2
Mockenhaupt, D.3
McCann, P.P.4
Diekma, K.A.5
Pegg, A.A.6
Nathan, H.C.7
Mullaney, E.A.8
Chunosoff, L.T.9
Sjoerdsma, A.10
Hutner, S.H.11
-
2
-
-
0031193927
-
Rapid methylation of cell proteins and lipids in Trypanosoma brucei
-
Goldberg B, Yarlett N, Rattendi D, Lloyd D and Bacchi CJ, Rapid methylation of cell proteins and lipids in Trypanosoma brucei. J Eukaryot Microbiol 44: 345-351, 1997.
-
(1997)
J Eukaryot Microbiol
, vol.44
, pp. 345-351
-
-
Goldberg, B.1
Yarlett, N.2
Rattendi, D.3
Lloyd, D.4
Bacchi, C.J.5
-
3
-
-
0027408676
-
S-Adenosylmethionine synthetase in bloodstream Trypanosoma brucei
-
Yarlett N, Garofalo J, Goldberg B, Ciminelli MA, Ruggiero V, Sufrin JR and Bacchi CJ, S-Adenosylmethionine synthetase in bloodstream Trypanosoma brucei. Biochim Biophys Acta 1181: 68-76, 1993.
-
(1993)
Biochim Biophys Acta
, vol.1181
, pp. 68-76
-
-
Yarlett, N.1
Garofalo, J.2
Goldberg, B.3
Ciminelli, M.A.4
Ruggiero, V.5
Sufrin, J.R.6
Bacchi, C.J.7
-
4
-
-
0029090729
-
Fate of soluble methionine in African trypanosomes: Effects of metabolic inhibitors
-
Bacchi CJ, Goldberg B, Garofalo-Hannan J, Rattendi D, Lyte P and Yarlett N, Fate of soluble methionine in African trypanosomes: Effects of metabolic inhibitors. Biochem J 309: 737-743, 1995.
-
(1995)
Biochem J
, vol.309
, pp. 737-743
-
-
Bacchi, C.J.1
Goldberg, B.2
Garofalo-Hannan, J.3
Rattendi, D.4
Lyte, P.5
Yarlett, N.6
-
5
-
-
0023776651
-
Effect of DL-α-difluoromethylornithine on methionine cycle intermediates in Trypanosoma brucei brucei
-
Yarlett N and Bacchi CJ, Effect of DL-α-difluoromethylornithine on methionine cycle intermediates in Trypanosoma brucei brucei. Mol Biochem Parasitol 27: 1-10, 1988.
-
(1988)
Mol Biochem Parasitol
, vol.27
, pp. 1-10
-
-
Yarlett, N.1
Bacchi, C.J.2
-
6
-
-
0026033857
-
Anti-trypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-L-methionine
-
Byers TL, Bush TL, McCann PP and Bitonti AJ, Anti-trypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-L-methionine. Biochem J 274: 527-533, 1991.
-
(1991)
Biochem J
, vol.274
, pp. 527-533
-
-
Byers, T.L.1
Bush, T.L.2
McCann, P.P.3
Bitonti, A.J.4
-
7
-
-
0030993577
-
A unique transporter of S-adenosylmethionine in African trypanosomes
-
Goldberg B, Yarlett N, Sufrin J, Lloyd D and Bacchi CJ, A unique transporter of S-adenosylmethionine in African trypanosomes. FASEB J 11: 256-260, 1997.
-
(1997)
FASEB J
, vol.11
, pp. 256-260
-
-
Goldberg, B.1
Yarlett, N.2
Sufrin, J.3
Lloyd, D.4
Bacchi, C.J.5
-
8
-
-
0024492929
-
Transamination of methionine in humans
-
Blom HK, Boers GHJ, Van Den Elzen JPAM, Gahl WA and Tangerman A, Transamination of methionine in humans. Clin Sci 76: 43-49, 1989.
-
(1989)
Clin Sci
, vol.76
, pp. 43-49
-
-
Blom, H.K.1
Boers, G.H.J.2
Van Den Elzen, J.P.A.M.3
Gahl, W.A.4
Tangerman, A.5
-
9
-
-
0023630758
-
Pharmacologic aspects of S-adenosylmethionine: Pharmacokinetics and pharmacodynamics
-
Stramentinoli G, Pharmacologic aspects of S-adenosylmethionine: Pharmacokinetics and pharmacodynamics. Am J Med 83: 35-42, 1987.
-
(1987)
Am J Med
, vol.83
, pp. 35-42
-
-
Stramentinoli, G.1
-
10
-
-
0002957502
-
Purine and pyrimidine metabolism
-
Eds. Marr JJ and Müller M, Academic Press, New York
-
Berens RL, Krug EC and Marr JJ, Purine and pyrimidine metabolism. In: Biochemistry and Molecular Biology of Parasites (Eds. Marr JJ and Müller M), pp. 89-117. Academic Press, New York, 1995.
-
(1995)
Biochemistry and Molecular Biology of Parasites
, pp. 89-117
-
-
Berens, R.L.1
Krug, E.C.2
Marr, J.J.3
-
11
-
-
0028875686
-
2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei
-
2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei. J Biol Chem 270: 1-5, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 1-5
-
-
Carter, N.S.1
Berger, B.J.2
Fairlamb, A.H.3
-
12
-
-
0023151184
-
Two high affinity nucleoside transporters in Leishmania donovani
-
Aronow B, Kaur K, McCartan K and Ullman B, Two high affinity nucleoside transporters in Leishmania donovani. Mol Biochem Parasitol 22: 29-37, 1987.
-
(1987)
Mol Biochem Parasitol
, vol.22
, pp. 29-37
-
-
Aronow, B.1
Kaur, K.2
McCartan, K.3
Ullman, B.4
-
13
-
-
0026647850
-
Nucleoside transporters in Leishmania major: Diversity in adenosine transporter expression or function in different strains
-
Baer HP, Serignese V, Ogbunude POJ and Dzimiri M, Nucleoside transporters in Leishmania major: Diversity in adenosine transporter expression or function in different strains. Am J Trop Med Hyg 47: 87-91, 1992.
-
(1992)
Am J Trop Med Hyg
, vol.47
, pp. 87-91
-
-
Baer, H.P.1
Serignese, V.2
Ogbunude, P.O.J.3
Dzimiri, M.4
-
14
-
-
0019226852
-
Uptake of purine bases and nucleosides in African trypanosomes
-
James DM and Born GVR, Uptake of purine bases and nucleosides in African trypanosomes. Parasitology 81: 383-393, 1980.
-
(1980)
Parasitology
, vol.81
, pp. 383-393
-
-
James, D.M.1
Born, G.V.R.2
-
15
-
-
0027500261
-
Arsenical-resistant trypanosomes lack an unusual adenosine transporter
-
Carter NS and Fairlamb AH, Arsenical-resistant trypanosomes lack an unusual adenosine transporter. Nature 361: 173-176, 1993.
-
(1993)
Nature
, vol.361
, pp. 173-176
-
-
Carter, N.S.1
Fairlamb, A.H.2
-
16
-
-
0027457469
-
Active transport of L-proline in the protozoan parasite Trypanosoma brucei brucei
-
L'Hostis C, Geindre M and Deshusses J, Active transport of L-proline in the protozoan parasite Trypanosoma brucei brucei. Biochem J 291: 297-301, 1993.
-
(1993)
Biochem J
, vol.291
, pp. 297-301
-
-
L'Hostis, C.1
Geindre, M.2
Deshusses, J.3
-
17
-
-
0029937062
-
In vitro trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors
-
Brun R, Buhler Y, Sandmeier U, Kaminsky R, Bacchi CJ, Rattendi D, Lane S, Croft SL, Snowdon D, Yardley V, Carvavatti G, Frei J, Stanke J and Mett H, In vitro trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors. Antimicrob Agents Chemother 40: 1442-1447, 1996.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 1442-1447
-
-
Brun, R.1
Buhler, Y.2
Sandmeier, U.3
Kaminsky, R.4
Bacchi, C.J.5
Rattendi, D.6
Lane, S.7
Croft, S.L.8
Snowdon, D.9
Yardley, V.10
Carvavatti, G.11
Frei, J.12
Stanke, J.13
Mett, H.14
-
18
-
-
0029937062
-
In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors
-
Bacchi CJ, Brun R, Croft SL, Alicea K and Buhler Y, In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors. Antimicrob Agents Chemother 40: 1448-1453, 1996.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 1448-1453
-
-
Bacchi, C.J.1
Brun, R.2
Croft, S.L.3
Alicea, K.4
Buhler, Y.5
-
19
-
-
0026109699
-
Differential sensitivity of Trypanosoma brucei rhodesiense isolates to in vitro lysis by arsenicals
-
Yarlett N, Goldberg B, Nathan HC, Garofalo J and Bacchi CJ, Differential sensitivity of Trypanosoma brucei rhodesiense isolates to in vitro lysis by arsenicals. Exp Parasitol 72: 205-215, 1991.
-
(1991)
Exp Parasitol
, vol.72
, pp. 205-215
-
-
Yarlett, N.1
Goldberg, B.2
Nathan, H.C.3
Garofalo, J.4
Bacchi, C.J.5
-
20
-
-
0026056623
-
Targeting 5′-deoxy-5′-(methylthio)adenosine phosphorylase by 5′-haloalkyl analogues of 5′-deoxy-5′-(methylthio)adenosine
-
Sufrin JR, Spiess AJ, Kramer DL, Libby PR, Miller JT, Bernacki RJ, Lee YH, Borchardt RT and Porter CW, Targeting 5′-deoxy-5′-(methylthio)adenosine phosphorylase by 5′-haloalkyl analogues of 5′-deoxy-5′-(methylthio)adenosine. J Med Chem 34: 2600-2606, 1991.
-
(1991)
J Med Chem
, vol.34
, pp. 2600-2606
-
-
Sufrin, J.R.1
Spiess, A.J.2
Kramer, D.L.3
Libby, P.R.4
Miller, J.T.5
Bernacki, R.J.6
Lee, Y.H.7
Borchardt, R.T.8
Porter, C.W.9
-
22
-
-
0022405635
-
Differential effect of sinefungin and its analogs on the multiplication of three Leishmania species
-
Paolantonacci P, Lawrence F and Robert-Gero M, Differential effect of sinefungin and its analogs on the multiplication of three Leishmania species. Antimicrob Agents Chemother 28: 528-531, 1985.
-
(1985)
Antimicrob Agents Chemother
, vol.28
, pp. 528-531
-
-
Paolantonacci, P.1
Lawrence, F.2
Robert-Gero, M.3
-
23
-
-
0021235148
-
Biochemical genetic analysis of formycin B action in Leishmania donovani
-
Robinson N, Kaur K, Emmett K, lovannisci DM and Ullman B, Biochemical genetic analysis of formycin B action in Leishmania donovani. J Biol Chem 259: 7637-7643, 1984.
-
(1984)
J Biol Chem
, vol.259
, pp. 7637-7643
-
-
Robinson, N.1
Kaur, K.2
Emmett, K.3
Lovannisci, D.M.4
Ullman, B.5
-
24
-
-
0025775689
-
5′-Alkyl-substituted analogs of 5′-methylthioadenosine as trypanocides
-
Bacchi CJ, Sufrin JR, Nathan HC, Spiess AJ, Hannan T, Garofalo J, Alicea K, Katz L and Yarlett N, 5′-Alkyl-substituted analogs of 5′-methylthioadenosine as trypanocides. Antimicrob Agents Chemother 35: 1315-1320, 1991.
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 1315-1320
-
-
Bacchi, C.J.1
Sufrin, J.R.2
Nathan, H.C.3
Spiess, A.J.4
Hannan, T.5
Garofalo, J.6
Alicea, K.7
Katz, L.8
Yarlett, N.9
-
25
-
-
0029861736
-
Antitrypanosomal activity of purine nucleosides can be enhanced by their conversion to O-acetylated derivatives
-
Sufrin JR, Rattendi D, Spiess AJ, Lane S, Marasco CJ Jr and Bacchi CJ, Antitrypanosomal activity of purine nucleosides can be enhanced by their conversion to O-acetylated derivatives. Antimicrob Agents Chemother 40: 2567-2572, 1996.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 2567-2572
-
-
Sufrin, J.R.1
Rattendi, D.2
Spiess, A.J.3
Lane, S.4
Marasco C.J., Jr.5
Bacchi, C.J.6
-
26
-
-
0030812873
-
In vivo efficacies of 5′-methylthioadenosine analogs as trypanocides
-
Bacchi CJ, Sanabria K, Spiess AJ, Vargas M, Marasco C Jr, Jiminez LM, Goldberg B and Sufrin JR, In vivo efficacies of 5′-methylthioadenosine analogs as trypanocides. Antimicrob Agents Chemother 42: 2108-2112, 1997.
-
(1997)
Antimicrob Agents Chemother
, vol.42
, pp. 2108-2112
-
-
Bacchi, C.J.1
Sanabria, K.2
Spiess, A.J.3
Vargas, M.4
Marasco C., Jr.5
Jiminez, L.M.6
Goldberg, B.7
Sufrin, J.R.8
-
27
-
-
0025180260
-
Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine
-
Bitonti AJ, Byers TL, Bush TL, Casara PJ, Bacchi CJ, Clarkson AB Jr, McCann PP and Sjoerdsma A, Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine. Antimicrob Agents Chemother 34: 1485-1490, 1990.
-
(1990)
Antimicrob Agents Chemother
, vol.34
, pp. 1485-1490
-
-
Bitonti, A.J.1
Byers, T.L.2
Bush, T.L.3
Casara, P.J.4
Bacchi, C.J.5
Clarkson A.B., Jr.6
McCann, P.P.7
Sjoerdsma, A.8
-
28
-
-
0027510003
-
S-Adenosylmethionine decarboxylase inhibitors: New aryl and heteroaryl analogues of methylglyoxal bis(guanylhydrazone)
-
Stanek J, Caravatti G, Capraro H-G, Furet P, Mett H, Schneider P and Regenass U, S-Adenosylmethionine decarboxylase inhibitors: New aryl and heteroaryl analogues of methylglyoxal bis(guanylhydrazone). J Med Chem 36: 46-54, 1993.
-
(1993)
J Med Chem
, vol.36
, pp. 46-54
-
-
Stanek, J.1
Caravatti, G.2
Capraro, H.-G.3
Furet, P.4
Mett, H.5
Schneider, P.6
Regenass, U.7
-
29
-
-
0022454288
-
Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone)
-
Bitonti AJ, Dumont JA and McCann PP, Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone). Biochem J 237: 685-689, 1986.
-
(1986)
Biochem J
, vol.237
, pp. 685-689
-
-
Bitonti, A.J.1
Dumont, J.A.2
McCann, P.P.3
-
30
-
-
0031194486
-
Effects of carboxylmethylation and polyamine synthesis inhibitors on methylation of Trypanosoma brucei cellular proteins and lipids
-
Goldberg B, Rattendi D, Yarlett N, Lloyd D and Bacchi CJ, Effects of carboxylmethylation and polyamine synthesis inhibitors on methylation of Trypanosoma brucei cellular proteins and lipids. J Eukaryot Microbiol 44: 352-358, 1997.
-
(1997)
J Eukaryot Microbiol
, vol.44
, pp. 352-358
-
-
Goldberg, B.1
Rattendi, D.2
Yarlett, N.3
Lloyd, D.4
Bacchi, C.J.5
-
31
-
-
0027510274
-
Uptake and metabolism of S-adenosyl-L-methionine by Leishmania mexicana and Leishmania braziliensis promastigotes
-
Avila JL and Polegre MA, Uptake and metabolism of S-adenosyl-L-methionine by Leishmania mexicana and Leishmania braziliensis promastigotes. Mol Biochem Parasitol 58: 123-134, 1993.
-
(1993)
Mol Biochem Parasitol
, vol.58
, pp. 123-134
-
-
Avila, J.L.1
Polegre, M.A.2
-
32
-
-
0027661598
-
Distribution of macromolecular methylations in promastigotes Leishmania donovani and impact of sinefungin
-
Lawrence F and Robert-Gero M, Distribution of macromolecular methylations in promastigotes Leishmania donovani and impact of sinefungin. J Eukaryot Microbiol 40: 581-589, 1993.
-
(1993)
J Eukaryot Microbiol
, vol.40
, pp. 581-589
-
-
Lawrence, F.1
Robert-Gero, M.2
-
33
-
-
0022483087
-
Interference with polyamine biosynthesis and/or function by analogs of polyamines or methionine as a potent anticancer chemotherapeutic strategy
-
Porter CW and Sufrin JR, Interference with polyamine biosynthesis and/or function by analogs of polyamines or methionine as a potent anticancer chemotherapeutic strategy. Anticancer Res 6: 525-542, 1986.
-
(1986)
Anticancer Res
, vol.6
, pp. 525-542
-
-
Porter, C.W.1
Sufrin, J.R.2
-
34
-
-
0025362827
-
Methionine metabolism in mammals
-
Finkelstein JD, Methionine metabolism in mammals. J Nutr Biochem 1: 228-236, 1990.
-
(1990)
J Nutr Biochem
, vol.1
, pp. 228-236
-
-
Finkelstein, J.D.1
-
35
-
-
0027340303
-
Nucleoside transport in parasites - Current status and methodological aspects
-
Ogbunude POJ and Baer HP, Nucleoside transport in parasites - Current status and methodological aspects. Int J Biochem 25: 471-477, 1993.
-
(1993)
Int J Biochem
, vol.25
, pp. 471-477
-
-
Ogbunude, P.O.J.1
Baer, H.P.2
-
36
-
-
0025324294
-
Differential susceptibility of DL-α-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense
-
Bacchi CJ, Nathan HC, Livingston T, Valladares G, Saric M, Sayer PD, Njogu AR and Clarkson AB Jr, Differential susceptibility of DL-α-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense. Antimicrob Agents Chemother 34: 1183-1188, 1990.
-
(1990)
Antimicrob Agents Chemother
, vol.34
, pp. 1183-1188
-
-
Bacchi, C.J.1
Nathan, H.C.2
Livingston, T.3
Valladares, G.4
Saric, M.5
Sayer, P.D.6
Njogu, A.R.7
Clarkson A.B., Jr.8
-
37
-
-
0017259974
-
Pentamidine transport in Trypanosoma brucei - Kinetics and specificity
-
Damper D and Patton CL, Pentamidine transport in Trypanosoma brucei - Kinetics and specificity. Biochem Pharmacol 25: 271-276, 1976.
-
(1976)
Biochem Pharmacol
, vol.25
, pp. 271-276
-
-
Damper, D.1
Patton, C.L.2
-
38
-
-
0345479418
-
Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense
-
Frommel TO and Balber AE, Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense. Mol Biochem Parasitol 26: 183-191, 1987.
-
(1987)
Mol Biochem Parasitol
, vol.26
, pp. 183-191
-
-
Frommel, T.O.1
Balber, A.E.2
-
39
-
-
0030009650
-
Pentamidine uptake in Leishmania donovani and Leishmania amazonensis promastigotes and axenic mastigotes
-
Basselin M, Lawrence F and Robert-Gero M, Pentamidine uptake in Leishmania donovani and Leishmania amazonensis promastigotes and axenic mastigotes. Biochem J 315: 631-634, 1996.
-
(1996)
Biochem J
, vol.315
, pp. 631-634
-
-
Basselin, M.1
Lawrence, F.2
Robert-Gero, M.3
-
40
-
-
0030906370
-
The acquisition of purines by trypanosomatids
-
Cohn CS and Gottleib M, The acquisition of purines by trypanosomatids. Parasitol Today 13: 231-235, 1997.
-
(1997)
Parasitol Today
, vol.13
, pp. 231-235
-
-
Cohn, C.S.1
Gottleib, M.2
|