DNA vaccination encoding glutamic acid decarboxylase can enhance insulitis and diabetes in correlation with a specific Th2/3 CD4 T cell response in non-obese diabetic mice

Clinical and Experimental Immunology

Volumn 137, Issue 2, 2004, Pages 253-262

  Gauvrit, A ^a   Debailleul, M ^a   Vu, A T ^a   Sai P ^a   Bach, J M ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

DNA vaccination; Glutamate decarboxylase; Insulitis; Th2 3 T cells; Type I diabetes

Indexed keywords

BETA GALACTOSIDASE; CD4 ANTIGEN; DNA VACCINE; GLUTAMATE DECARBOXYLASE; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; INTERLEUKIN 4; PLASMID DNA; TRANSFORMING GROWTH FACTOR BETA;

ALLERGY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DIABETES MELLITUS; FEMALE; IMMUNIZATION; INSULITIS; LYMPH NODE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PANCREAS DISEASE; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE; TH2 CELL; TIBIALIS ANTERIOR MUSCLE; VACCINATION;

ANIMALS; BETA-GALACTOSIDASE; CELL DIVISION; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DNA-BINDING PROTEINS; FEMALE; GLUTAMATE DECARBOXYLASE; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED NOD; MUSCLE, SKELETAL; PLASMIDS; T-LYMPHOCYTE SUBSETS; TH2 CELLS; VACCINES, DNA;

EID: 3543046812     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02546.x     Document Type: Article

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