The role of fluorine in the stereoselective tandem aza-Michael addition to acrylamide acceptors: An experimental and theoretical mechanistic study

Chemistry - A European Journal

Volumn 13, Issue 30, 2007, Pages 8530-8542

  Fustero, Santos ^a,b   Chiva, Gema ^a,b   Piera, Julio ^a,b   Volonterio, Alessandro ^c   Zanda, Matteo ^d   González, Javier ^e   Ramallal, Antonio Morán ^e  

^a UNIVERSITY OF VALENCIA   (Spain)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^c POLITECNICO DI MILANO   (Italy)

^d CNR   (Italy)

^e UNIVERSITY OF OVIEDO   (Spain)

Author keywords

Density functional calculations; Diastereoselectivity; Fluorine chemistry; Michael reaction; Peptides

Indexed keywords

ACRYLAMIDE ACCEPTORS; DIASTEREOSELECTIVITY; MICHAEL REACTIONS; RETROPEPTIDES; TANDEM AZA;

AMIDES; AMINO ACIDS; DENSITY FUNCTIONAL THEORY; ESTERS; FLUORINE; PEPTIDES; STEREOSELECTIVITY;

AROMATIC COMPOUNDS;

ACRYLAMIDE; FLUORINE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM;

ACRYLAMIDE; FLUORINE; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, MOLECULAR; STEREOISOMERISM;

EID: 35349019315     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200700393     Document Type: Article

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