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Volumn 73, Issue 11, 2007, Pages 1192-1194

Induction of apoptosis and regulation of the MAPK pathway by ursolic acid in human leukemia K562 cells

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL XL; STRESS ACTIVATED PROTEIN KINASE; URSOLIC ACID;

EID: 35348861389     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-981597     Document Type: Article
Times cited : (47)

References (23)
  • 1
    • 0023760949 scopus 로고
    • The cytotoxic principles of Prunella vulgaris, Psychotria serpens, and Hyptis capitata: Ursolic acid and related derivatives
    • Lee KH, Lin YM, Wu TS, Zhang DC, Yamagishi T, Hayashi T et al. The cytotoxic principles of Prunella vulgaris, Psychotria serpens, and Hyptis capitata: ursolic acid and related derivatives. Planta Med 1988; 54: 308-11.
    • (1988) Planta Med , vol.54 , pp. 308-311
    • Lee, K.H.1    Lin, Y.M.2    Wu, T.S.3    Zhang, D.C.4    Yamagishi, T.5    Hayashi, T.6
  • 2
    • 0034805595 scopus 로고    scopus 로고
    • Sterols, triterpenes and biflavonoids of Viburnum jucundum and cytotoxic activity of ursolic acid
    • Rios MY, Gonzalez-Morales A, Villarreal ML. Sterols, triterpenes and biflavonoids of Viburnum jucundum and cytotoxic activity of ursolic acid. Planta Med 2001; 67: 683-4.
    • (2001) Planta Med , vol.67 , pp. 683-684
    • Rios, M.Y.1    Gonzalez-Morales, A.2    Villarreal, M.L.3
  • 4
    • 0029960889 scopus 로고    scopus 로고
    • MCF-7 cell cycle arrested at G1 through ursolic acid, and increased reduction of tetrazolium salts
    • Es-Saady D, Simon A, Jayat-Vignoles C, Chulia AJ, Delage C. MCF-7 cell cycle arrested at G1 through ursolic acid, and increased reduction of tetrazolium salts. Anticancer Res 1996; 16: 481-6.
    • (1996) Anticancer Res , vol.16 , pp. 481-486
    • Es-Saady, D.1    Simon, A.2    Jayat-Vignoles, C.3    Chulia, A.J.4    Delage, C.5
  • 6
    • 27944489889 scopus 로고    scopus 로고
    • Glycyrrhetinic acid and related compounds induce G1 arrest and apoptosis in human hepatocellular carcinoma HepG2
    • Satomi Y, Nishino H, Shibata S. Glycyrrhetinic acid and related compounds induce G1 arrest and apoptosis in human hepatocellular carcinoma HepG2. Anticancer Res 2005; 25: 4043-7.
    • (2005) Anticancer Res , vol.25 , pp. 4043-4047
    • Satomi, Y.1    Nishino, H.2    Shibata, S.3
  • 7
    • 0034266625 scopus 로고    scopus 로고
    • Induction of apoptosis by ursolic acid through activation of caspases and downregulation of c-IAPs in human prostate epithelial cells
    • Choi YH, Baek JH, Yoo MA, Chung HY, Kim ND, Kim KW. Induction of apoptosis by ursolic acid through activation of caspases and downregulation of c-IAPs in human prostate epithelial cells. Int J Oncol 2000; 17:565-71.
    • (2000) Int J Oncol , vol.17 , pp. 565-571
    • Choi, Y.H.1    Baek, J.H.2    Yoo, M.A.3    Chung, H.Y.4    Kim, N.D.5    Kim, K.W.6
  • 8
    • 11144352711 scopus 로고    scopus 로고
    • Apoptosis inducing activity of viscin, a lipophilic extract from Viscum album L
    • Urech K, Scher JM, Hostanska K, Becker H. Apoptosis inducing activity of viscin, a lipophilic extract from Viscum album L. J Pharm Pharmacol 2005; 57: 101-9.
    • (2005) J Pharm Pharmacol , vol.57 , pp. 101-109
    • Urech, K.1    Scher, J.M.2    Hostanska, K.3    Becker, H.4
  • 9
    • 0035570087 scopus 로고    scopus 로고
    • Activation of caspase-3 protease during the process of ursolic acid and its derivative-induced apoptosis
    • Hollosy F, Idei M, Csorba G, Szabo E, Bokonyi G, Seprodi A et al. Activation of caspase-3 protease during the process of ursolic acid and its derivative-induced apoptosis. Anticancer Res 2001; 21: 3485-91.
    • (2001) Anticancer Res , vol.21 , pp. 3485-3491
    • Hollosy, F.1    Idei, M.2    Csorba, G.3    Szabo, E.4    Bokonyi, G.5    Seprodi, A.6
  • 10
    • 13244255330 scopus 로고    scopus 로고
    • Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells
    • Harmand PO, Duval R, Delage C, Simon A. Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells. Int J Cancer 2005; 114: 1-11.
    • (2005) Int J Cancer , vol.114 , pp. 1-11
    • Harmand, P.O.1    Duval, R.2    Delage, C.3    Simon, A.4
  • 12
    • 0033983015 scopus 로고    scopus 로고
    • Cyclic adenosine monophosphate inhibits ursolic acid-induced apoptosis via activation of protein kinase A in human leukaemic HL-60 cells
    • Choi BM, Park R, Pae HO, Yoo JC, Kim YC, Jun CD et al. Cyclic adenosine monophosphate inhibits ursolic acid-induced apoptosis via activation of protein kinase A in human leukaemic HL-60 cells. Pharmacol Toxicol 2000; 86: 53-8.
    • (2000) Pharmacol Toxicol , vol.86 , pp. 53-58
    • Choi, B.M.1    Park, R.2    Pae, H.O.3    Yoo, J.C.4    Kim, Y.C.5    Jun, C.D.6
  • 13
    • 4444356923 scopus 로고    scopus 로고
    • Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells
    • Hsu YL, Kuo PL, Lin CC. Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells. Life Sci 2004; 75: 303-16.
    • (2004) Life Sci , vol.75 , pp. 303-316
    • Hsu, Y.L.1    Kuo, P.L.2    Lin, C.C.3
  • 14
    • 33846509838 scopus 로고    scopus 로고
    • Regulation of the phosphatidylinositol 3-kinase-Akt and the mitogen-activated protein kinase pathways by ursolic acid in human endometrial cancer cells
    • Achiwa Y, Hasegawa K, Udagawa Y. Regulation of the phosphatidylinositol 3-kinase-Akt and the mitogen-activated protein kinase pathways by ursolic acid in human endometrial cancer cells. Biosci Biotechnol Biochem 2007; 71: 31-7.
    • (2007) Biosci Biotechnol Biochem , vol.71 , pp. 31-37
    • Achiwa, Y.1    Hasegawa, K.2    Udagawa, Y.3
  • 15
    • 0034477152 scopus 로고    scopus 로고
    • Cytostatic, cytotoxic and protein tyrosine kinase inhibitory activity of ursolic acid in A431 human tumor cells
    • Hollosy F, Meszaros G, Bokonyi G, Idei M, Seprodi A, Szende B et al. Cytostatic, cytotoxic and protein tyrosine kinase inhibitory activity of ursolic acid in A431 human tumor cells. Anticancer Res 2000; 20: 4563-70.
    • (2000) Anticancer Res , vol.20 , pp. 4563-4570
    • Hollosy, F.1    Meszaros, G.2    Bokonyi, G.3    Idei, M.4    Seprodi, A.5    Szende, B.6
  • 16
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000; 103: 239-52.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 17
    • 0037230304 scopus 로고    scopus 로고
    • Activation of the JNK signaling pathway: Breaking the brake on apoptosis
    • Lin A. Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 2003; 25: 17-24.
    • (2003) Bioessays , vol.25 , pp. 17-24
    • Lin, A.1
  • 18
    • 34247562264 scopus 로고    scopus 로고
    • Arsenic trioxide represses NF-kappaB activation and increases apoptosis in ATRA-treated APL cells
    • Mathieu J, Besancon F. Arsenic trioxide represses NF-kappaB activation and increases apoptosis in ATRA-treated APL cells. Ann N Y Acad Sci 2006; 1090: 203-8.
    • (2006) Ann N Y Acad Sci , vol.1090 , pp. 203-208
    • Mathieu, J.1    Besancon, F.2
  • 21
    • 0042090509 scopus 로고    scopus 로고
    • Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: Correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1
    • Shishodia S, Majumdar S, Banerjee S, Aggarwal BB. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1. Cancer Res 2003; 63: 4375-83.
    • (2003) Cancer Res , vol.63 , pp. 4375-4383
    • Shishodia, S.1    Majumdar, S.2    Banerjee, S.3    Aggarwal, B.B.4
  • 22
    • 0345561544 scopus 로고    scopus 로고
    • Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons
    • Tamatani M, Che YH, Matsuzaki H, Ogawa S, Okado H, Miyake S. Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons. J Biol Chem 1999; 274: 8531-8.
    • (1999) J Biol Chem , vol.274 , pp. 8531-8538
    • Tamatani, M.1    Che, Y.H.2    Matsuzaki, H.3    Ogawa, S.4    Okado, H.5    Miyake, S.6
  • 23
    • 33744899623 scopus 로고    scopus 로고
    • Matrine-induced apoptosis in leukemia U937 cells: Involvement of caspases activation and MAPK-independent pathways
    • Liu XS, Jiang J, Jiao XY, Wu YE, Lin JH. Matrine-induced apoptosis in leukemia U937 cells: involvement of caspases activation and MAPK-independent pathways. Planta Med 2006; 72: 501-6.
    • (2006) Planta Med , vol.72 , pp. 501-506
    • Liu, X.S.1    Jiang, J.2    Jiao, X.Y.3    Wu, Y.E.4    Lin, J.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.