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Volumn 25, Issue 6 B, 2005, Pages 4043-4047

Glycyrrhetinic acid and related compounds induce G1 arrest and apoptosis in human hepatocellular carcinoma HepG2

Author keywords

Apoptosis; Bcl 2 family; G1 arrest; Glycyrrhetinic acid; Glycyrrhizin; Hepatocellular carcinoma

Indexed keywords

18BETA OLEAN 12 ENE 3BETA,23,28 TRIOL; ANTINEOPLASTIC AGENT; CASPASE 8; CASPASE 9; CONNEXIN 32; DNA; GAP JUNCTION PROTEIN; GLYCYRRHETINIC ACID; OLEANOLIC ACID; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; UNCLASSIFIED DRUG; URSOLIC ACID;

EID: 27944489889     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (113)

References (21)
  • 3
    • 0023431016 scopus 로고
    • Effects of glycyrrhizin and glycyrrhetinic acid on growth and melanogenesis in cultured B16 melanoma cells
    • Abe H, Ohya N, Fujikawa-Yamamoto K, Shibuya T, Arichi S and Odashima S: Effects of glycyrrhizin and glycyrrhetinic acid on growth and melanogenesis in cultured B16 melanoma cells. Eur J Cancer Clin Oncol 23: 1549-1555, 1987.
    • (1987) Eur J Cancer Clin Oncol , vol.23 , pp. 1549-1555
    • Abe, H.1    Ohya, N.2    Fujikawa-Yamamoto, K.3    Shibuya, T.4    Arichi, S.5    Odashima, S.6
  • 5
    • 0038649361 scopus 로고    scopus 로고
    • Effect of glycyrrhizin, an active component of licorice roots, on HIV replication in cultures of peripheral blood mononuclear cells from HIV-seropositive patients
    • Sasaki H, Takei M, Kobayashi M, Pollard RB and Suzuki F: Effect of glycyrrhizin, an active component of licorice roots, on HIV replication in cultures of peripheral blood mononuclear cells from HIV-seropositive patients. Pathobiology 70: 229-236, 2003.
    • (2003) Pathobiology , vol.70 , pp. 229-236
    • Sasaki, H.1    Takei, M.2    Kobayashi, M.3    Pollard, R.B.4    Suzuki, F.5
  • 6
    • 0020315403 scopus 로고
    • Interferon induction by glycyrrhizin and glycyrrhetinic acid in mice
    • Abe N, Ebina T and Ishida N: Interferon induction by glycyrrhizin and glycyrrhetinic acid in mice. Microbiol Immunol 26: 535-539, 1982.
    • (1982) Microbiol Immunol , vol.26 , pp. 535-539
    • Abe, N.1    Ebina, T.2    Ishida, N.3
  • 9
    • 0023732557 scopus 로고
    • Inhibition of the tumor-promoting action of 12-O-tetradecanoylphorbol-13- acetate by some oleanane-type triterpenoid compounds
    • Nishino H, Nishino A, Takayasu J, Hasegawa T, Iwashima A, Hirabayashi K, Iwata S and Shibata S: Inhibition of the tumor-promoting action of 12-O-tetradecanoylphorbol-13-acetate by some oleanane-type triterpenoid compounds. Cancer Res 48: 5210-5215, 1988.
    • (1988) Cancer Res , vol.48 , pp. 5210-5215
    • Nishino, H.1    Nishino, A.2    Takayasu, J.3    Hasegawa, T.4    Iwashima, A.5    Hirabayashi, K.6    Iwata, S.7    Shibata, S.8
  • 10
    • 0022620229 scopus 로고
    • Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid
    • Davidson JS, Baumgarten IM and Harley EH: Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid. Biochem Biophys Res Commun 134: 29-36, 1986.
    • (1986) Biochem Biophys Res Commun , vol.134 , pp. 29-36
    • Davidson, J.S.1    Baumgarten, I.M.2    Harley, E.H.3
  • 11
    • 0023795464 scopus 로고
    • Glycyrrhetinic acid derivatives: A novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships
    • Davidson JS and Baumgarten IM: Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships. J Pharm Exp Ther 246: 1104-1107, 1988.
    • (1988) J Pharm Exp Ther , vol.246 , pp. 1104-1107
    • Davidson, J.S.1    Baumgarten, I.M.2
  • 12
    • 0029757386 scopus 로고    scopus 로고
    • Gap-junction disassembly and connexin 43 dephosphorylation induced by 18β-glycyrrhetinic acid
    • Guan X, Wilson S, Schlender KK and Ruch RJ: Gap-junction disassembly and connexin 43 dephosphorylation induced by 18β-glycyrrhetinic acid. Mol Carcinogenesis 16: 157-164, 1996.
    • (1996) Mol Carcinogenesis , vol.16 , pp. 157-164
    • Guan, X.1    Wilson, S.2    Schlender, K.K.3    Ruch, R.J.4
  • 13
    • 1442286330 scopus 로고    scopus 로고
    • The role of Bcl-2 family members in tumorigenesis
    • Kirkin V, Joos S and Zörnig M: The role of Bcl-2 family members in tumorigenesis. Biochem Biophys Acta 1644: 229-249, 2004.
    • (2004) Biochem Biophys Acta , vol.1644 , pp. 229-249
    • Kirkin, V.1    Joos, S.2    Zörnig, M.3
  • 14
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: Roles in cell survival and oncogenesis
    • Cory S, Huang DCS and Adams JM: The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22: 8590-8607, 2003.
    • (2003) Oncogene , vol.22 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.S.2    Adams, J.M.3
  • 15
    • 0035150543 scopus 로고    scopus 로고
    • Glycyrrhetinic acid induced apoptosis in murine splenocytes
    • Horigome H, Homma M, Hirano T and Oka K: Glycyrrhetinic acid induced apoptosis in murine splenocytes. Biol Pharm Bull 24: 54-58, 2001.
    • (2001) Biol Pharm Bull , vol.24 , pp. 54-58
    • Horigome, H.1    Homma, M.2    Hirano, T.3    Oka, K.4
  • 16
    • 0344585889 scopus 로고    scopus 로고
    • Glycyrrhetinic acid-induced permeability transition in rat liver mitochondria
    • Salvi M, Fiore C, Armanini D and Toninello A: Glycyrrhetinic acid-induced permeability transition in rat liver mitochondria. Biochem Pharm 66: 2375-2379, 2003.
    • (2003) Biochem Pharm , vol.66 , pp. 2375-2379
    • Salvi, M.1    Fiore, C.2    Armanini, D.3    Toninello, A.4
  • 17
    • 0035902794 scopus 로고    scopus 로고
    • The Chinese medicine Bu-Zhong-Yi-Qi-Tang inhibited proliferation of hepatoma cell lines by inducing apoptosis via G0/G1 arrest
    • Kao ST, Yeh CC, Hsieh CC, Yang MD, Lee MR, Liu HS and Lin JG: The Chinese medicine Bu-Zhong-Yi-Qi-Tang inhibited proliferation of hepatoma cell lines by inducing apoptosis via G0/G1 arrest. Life Sci 69: 1485-1496, 2001.
    • (2001) Life Sci , vol.69 , pp. 1485-1496
    • Kao, S.T.1    Yeh, C.C.2    Hsieh, C.C.3    Yang, M.D.4    Lee, M.R.5    Liu, H.S.6    Lin, J.G.7
  • 19
    • 0035991948 scopus 로고    scopus 로고
    • Gap junctions: Structure and function
    • Evans WH and Martin PEM: Gap junctions: structure and function (Review). Mol Membr Biol 19: 121-136, 2002.
    • (2002) Mol Membr Biol , vol.19 , pp. 121-136
    • Evans, W.H.1    Martin, P.E.M.2
  • 20
    • 0025374396 scopus 로고
    • Gap junctional intercellular communication and carcinogenesis
    • Yamasaki H: Gap junctional intercellular communication and carcinogenesis. Carcinogenesis 11: 1051-1058, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 1051-1058
    • Yamasaki, H.1
  • 21
    • 4344691959 scopus 로고    scopus 로고
    • Caspases, IAPs and Smac/DIABLO: Mechanisms from structural biology
    • Shiozaki EN and Shi Y: Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology. TRENDS Biochem Sci 39: 486-494, 2004.
    • (2004) TRENDS Biochem Sci , vol.39 , pp. 486-494
    • Shiozaki, E.N.1    Shi, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.