Calcium ionophore A23187 specifically decreases the secretion of β-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures

Journal of Neuroscience Research

Volumn 63, Issue 5, 2001, Pages 429-437

  Sennvik, Kristina ^a   Benedikz, Eirikur ^a   Fastbom, Johan ^a   Sundström, Erik ^a   Winblad, Bengt ^a   Ankarcrona, Maria ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Apoptosis; Primary cultures

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; CALCIMYCIN; COLCHICINE; GAMMA SECRETASE; LIPOCORTIN 5; PROPIDIUM IODIDE;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CELL VIABILITY; CONTROLLED STUDY; ENZYME RELEASE; FETUS; NERVE CELL CULTURE; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SENILE PLAQUE;

AMINO ACID CHLOROMETHYL KETONES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANNEXIN A5; APOPTOSIS; ASPARTIC ENDOPEPTIDASES; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CALCIMYCIN; CALCIUM; CELLS, CULTURED; CEREBRAL CORTEX; COLCHICINE; CULTURE MEDIA, CONDITIONED; CYSTEINE PROTEINASE INHIBITORS; CYTOSKELETON; ENDOPEPTIDASES; IONOPHORES; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035283128     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4547(20010301)63:5<429::AID-JNR1038>3.0.CO;2-U     Document Type: Article

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