Cell division cycle 25B phosphatase is essential for benzo(a)pyrene-7,8- diol-9,10-epoxide-induced neoplastic transformation

Cancer Research

Volumn 67, Issue 19, 2007, Pages 9150-9157

  Srivastava, Sanjay K ^a,b   Bansal, Pallavi ^a   Oguri, Tetsuya ^a   Lazo, John S ^a,b   Singh, Shivendra V ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CDC25B PHOSPHATASE; HYDROCARBON; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG; VINCULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DIVISION; COLONY FORMATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ANALYSIS; FEMALE; FIBROBLAST; GENE OVEREXPRESSION; IONIZING RADIATION; LUNG PARENCHYMA; MALIGNANT TRANSFORMATION; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; CARCINOGENS; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; DNA DAMAGE; ENZYME INDUCTION; FEMALE; FIBROBLASTS; HUMANS; LUNG; MALE; MICE; MICE, INBRED A; MICE, NUDE; PROTEIN KINASES;

EID: 35148852662     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-0025     Document Type: Article

References (39)

1. Monographs on the evaluation of the carcinogenic risk of chemicals to man. Chemical, environment, and experimental data. International Agency for Research on Cancer (IARC); 1983; Lyon, France; 1983.
2. Sims P, Glover PL Epoxides of polycyclic aromatic hydrocarbons: metabolism and carcinogenesis. Adv Cancer Res 1974;20:165-274.
3. Buening M, Wislocki PG, Levin W, et al. Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene-7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7β,8α-dihydroxy- 9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Proc Natl Acad Sci USA 1978;75:5358-61.
4. Slaga T, Bracken WJ, Gleason G, et al. Marked differences in the skin tumor-initiating activities of the optical enantiomers of the diastereomeric benzo[a]pyrene-7,8-diol-9,10-epoxide. Cancer Res 1979;39:67-71.
5. Thakker D, Yagi H, Levin W, Wood AW, Jerina DM. Bioactivation of foreign compounds. In: Anders MW, editor. New York (NY): Academic Press; 1985. p. 177-242.
6. Dipple AIHR, editor. Washington DC polycyclic hydrocarbons and carcinogenesis: an introduction. In: Harvey RG, editor. ACS Symposium Series. Washington (DC); 1991. p. 1-17.
7. Hu X, Srivastava SK, Xia H, Awasthi YC, Singh SV. An a class mouse glutathione S-transferase with exceptional catalytic efficiency in the conjugation of glutathione with 7β,8α-dihydroxy-9α,10α- oxy-7,8,9,10-tetrahydrobenzo( a)pyrene. J Biol Chem 1996;271:32684-8.
8. Boutros R, Dozier C, Ducommun B. The when and wheres of CDC25 phosphatases. Curr Opin Cell Biol 2006;18:185-91.
9. 2 DNA damage-induced arrest in mammalian cells. Mol Cell 2004;15:799-811.
10. 2-M checkpoint exit is dependent on CDC25B phosphatase expression. Mol Cancer Ther 2006;5:1446-51.
11. Galaktionov K, Lee AK, Eckstein J, et al. CDC25 phosphatases as potential human oncogenes. Science 1995;269:1575-7.
12. Gasparotto D, Maestro R, Piccinin S, et al. Overexpression of CDC25A and CDC25B in head and neck cancers. Cancer Res 1997;57:2366-8.
13. Takemasa I, Yamamoto H, Sekimoto M, et al. Overexpression of CDC25B phosphatase as a novel marker of poor prognosis of human colorectal carcinoma. Cancer Res 2000;60:3043-50.
14. Sasaki H, Yukiue H, Kobayashi Y, et al. Expression of the cdc25B gene as a prognosis marker in non-small cell lung cancer. Cancer Lett 2001;173:187-92.
15. Ma Z, Liu Z, Ngan ESW, Tsai SY. Cdc25B functions as a novel coactivator for the steroid receptors. Mol Cell Biol 2001;21:8056-67.
16. Ma Z, Chua SS, DeMayo FJ, Tsai SY. Induction of mammary gland hyperplasia in transgenic mice overexpressing human Cdc25B. Oncogene 1999;18:4564-76.
17. Yao Y, Slosberg ED, Wang L, et al. Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice. Oncogene 1999;18:5159-66.
18. Oguri T, Singh SV, Nemoto K, Lazo JS. The carcinogen (7R,8S)-dihydroxy- (9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[ a]pyrene induces Cdc25B expression in human bronchial and lung cancer cells. Cancer Res 2003;63:771-5.
19. Lincoln A, Wickramasinghe D, Stein P, et al. Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation. Nat Genet 2002;30:446-9.
20. Bansal P, Lazo JS. Induction of Cdc25B regulates cell cycle resumption after genotoxic stress. Cancer Res 2007;67:3356-63.
21. Singh A, Xiao D, Lew KL, Dhir R, Singh SV. Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo. Carcinogenesis 2004;25:83-90.
22. Sparnins V, Barany G, Wattenberg L. Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse. Carcinogenesis 1988;9:131-4.
23. Bi X, Barkley LR, Slater DM, et al. Rad18 regulates DNA polymerase κ and is required for recovery from S-phase checkpoint-mediated arrest. Mol Cell Biol 2006;26:3527-40.
24. Liu P, Barkley LR, Day T, et al. The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism. J Biol Chem 2006;281:30631-44.
25. Leung-Pineda V, Ryan CE, Piwnica-Worms H. Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit. Mol Cell Biol 2006;26:7529-38.
26. Bartkova J, Horejsi Z, Koed K, et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005;434:864-70.
27. Gorgoulis VG, Vassiliou LV, Karakaidos P, et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005;434:907-13.
28. Mailand N, Falck J, Lukas C, et al. Rapid destruction of human Cdc25A in response to DNA damage. Science 2000;288:1425-9.
29. Falck J, Mailand N, Syljuasen RG, Bartek J, Lukas J. The ATM-Chk2-25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 2001;410:842-7.
30. Bartek J, Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003;3:421-9.
31. Busino L, Chiesa M, Draetta GF, Donzelli M. Cdc25A phosphatase: combinatorial phosphorylation, ubiquitylation, and proteolysis. Oncogene 2004;23:2050-6.
32. 2/M arrest in human bronchoalveolar carcinoma H358 cells. Mol Pharmacol 2007;71:744-50.
33. 2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and polo-like kinase 1 kinases. Cancer Res 2006;66:10253-7.
34. Knecht R, Elez R, Oechler M, Solbach C, von Ilberg C, Strebhardt K. Prognostic significance of polo-like kinase (PLK) expression in squamous cell carcinomas of the head and neck. Cancer Res 1999;59:2794-7.
35. Wolf G, Elez R, Doermer A, et al. Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer. Oncogene 1997;14:543-9.
36. Yamada S, Ohira M, Horie H, et al. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. Oncogene 2004;23:5901-11.
37. Lam MH, Liu Q, Elledge SJ, Rosen JM. Chk1 is haploinsufficient for multiple functions critical to tumor suppression. Cancer Cell 2004;6:45-59.
38. Wani MA, Zhu Q, El-Mahdy M, Venkatachalam S, Wani AA. Enhanced sensitivity to anti-benzo(a)pyrenediol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells. Cancer Res 2000;60:2273-80.
39. Kang CM, Cho HN, Ahn JM, et al. Alteration of gene expression during radiation-induced resistance and tumorigenesis in NIH3T3 cells revealed by cDNA microarrays: involvement of MDM2 and CDC25B. Carcinogenesis 2004;25:123-32.