Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

Proceedings of the National Academy of Sciences of the United States of America

Volumn 75, Issue 11, 1978, Pages 5358-5361

  Buening, M K ^a   Wislocki, P G ^a   Levin, H ^a   Yagi, H ^b   Thakker, D R ^b   Akagi, H ^b   Koreeda, M ^b   Jerina, D M ^b   Conney, A H ^b  

^a HOFFMANN LA ROCHE INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDROXYBENZO[A]PYRENE 9,10 OXIDE; BENZO[A]PYRENE;

ANIMAL EXPERIMENT; CARCINOGENESIS; CARCINOGENICITY; DOSE RESPONSE; DRUG COMPARISON; DRUG RESPONSE; DRUG SCREENING; ENANTIOMER; INTRAPERITONEAL DRUG ADMINISTRATION; LUNG TUMOR; MOUSE; NEWBORN; RESPIRATORY SYSTEM; STRUCTURE ACTIVITY RELATION;

EID: 0000933858     PISSN: 00278424     EISSN: None     Source Type: None    
DOI: 10.1073/pnas.75.11.5358     Document Type: Article

References (0)