The cooked meat-derived genotoxic carcinogen 2-amino-3-methylimidazo[4,5-b] pyridine has potent hormone-like activity: Mechanistic support for a role in breast cancer

Cancer Research

Volumn 67, Issue 19, 2007, Pages 9597-9602

  Lauber, Sandra N ^a   Gooderham, Nigel J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 AMINO 3 METHYLIMIDAZO[4,5 B]PYRIDINE; ACYLTRANSFERASE; CARCINOGEN; CYTOCHROME P450 1A1; ESTROGEN; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; HETEROCYCLIC AMINE; MITOGEN ACTIVATED PROTEIN KINASE; PROGESTERONE RECEPTOR; PROLACTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CARCINOGENICITY; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; ENZYME IMMUNOASSAY; ESTROGEN ACTIVITY; GENOTOXICITY; HYPOPHYSIS CELL; IMMUNOBLOTTING; LYMPHOMA; MEAT; MOUSE; MUTATION; NONHUMAN; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; PROLACTIN RELEASE; PROSTATE CANCER; RAT; SIGNAL TRANSDUCTION; XENOBIOTIC METABOLISM;

ANIMALS; BREAST NEOPLASMS; CARCINOGENS; CELL GROWTH PROCESSES; ESTRADIOL; FLAVONOIDS; IMIDAZOLES; PITUITARY GLAND; PROLACTIN; RATS;

EID: 35148840117     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-1661     Document Type: Article

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