Estrogen modulation of prolactin gene expression requires an intact mitogen-activated protein kinase signal transduction pathway in cultured rat pituitary cells

Molecular Endocrinology

Volumn 14, Issue 11, 2000, Pages 1872-1881

  Watters, J J ^a   Chun, T Y ^a   Kim, Y N ^a   Bertics, P J ^a   Gorski, J ^a  

^a Department of Biochemistry ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; MITOGEN ACTIVATED PROTEIN KINASE; PROLACTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; ENZYME ACTIVITY; FEMALE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HORMONAL REGULATION; HYPOPHYSIS CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0033651438     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.14.11.0551     Document Type: Article

References (46)

1. Estradiol regulates the transcription of the prolactin gene
2. Analysis of 5' flanking sequences and intron-exon boundaries of the rat prolactin gene
3. Selective binding of the estradiol receptor to a region at least one kilobase upstream from the rat prolactin gene
4. Identification of an estrogen-responsive element from the 5'-flanking region of the rat prolactin gene
5. A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene
6. A protein kinase inhibitor gene reduces both basal and multihormone-stimulated prolactin gene transcription
7. Thyroid hormone-responsive elements of the prolactin gene: Evidence for both positive and negative regulation
8. Estrogen receptor selectively binds the 'coding strand' of an estrogen responsive element
9. Estrogen receptor binding to a DNA response element in vitro is not dependent upon estradiol
10. The distal enhancer region of the rat prolactin gene contains elements conferring response to multiple hormones
11. Both Pit-1 and the estrogen receptor are required for estrogen responsiveness of the rat prolactin gene
12. A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways
13. Multiple Pit-1-binding sites facilitate estrogen responsiveness of the prolactin gene
14. Increase in Pit-1 mRNA is not required for the estrogen-induced expression of prolactin gene and lactotroph proliferation
15. A Pit-1 phosphorylation mutant can mediate both basal and induced prolactin and growth hormone promoter activity
16. Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells
17. Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor
18. Non-transcriptional action of oestradiol and progestin triggers DNA synthesis
19. Differential effects of 17β-estradiol on mitogen-activated protein kinase pathways in rat cardiomyocytes
20. Rapid activation of MAP kinase by estrogen in the bone cell line
21. Estradiol activation of human colon carcinoma-derived Caco-2 cell growth
22. Differential regulation by estrogens of growth and prolactin synthesis in pituitary cells suggests that only a small pool of estrogen receptors is required for growth
23. Role of transforming growth factor (TGF)-β type I and TGF-β type II receptors in the TGF-β1-regulated gene expression in pituitary prolactin-secreting lactotropes
24. Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
25. 17β-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation, and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells
26. Estrogen-induced cyclin D1 and D3 gene expressions during mouse uterine cell proliferation in vivo: Differential induction mechanism of cyclin D1 and D3
27. Immediate and transient stimulation of protein tyrosine phosphorylation by estradiol in MCF-7 cells
28. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
29. c-Src, receptor tyrosine kinases, and human cancer
30. Src family tyrosine kinases and growth factor signaling
31. Estradiol stimulates prolactin gene transcription in primary cultures of rat anterior pituitary cells
32. Estrogen regulates the transcription of the rat prolactin gene in vivo through at least two independent mechanisms
33. Estrogen stimulates prolactin gene transcription by a mechanism independent of pituitary protein synthesis
34. Estradiol membrane binding sites on human breast cancer cell lines. Use of a fluorescent estradiol conjugate to demonstrate plasma membrane binding systems
35. Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand binding
36. Rapid membrane effects of steroids in neuroblastoma cells: Effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription
37. Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERα and ERβ expressed in Chinese hamster ovary cells
38. Estrogen receptor-α detected on the plasma membrane of aldehyde-fixed GH3/B6/F10 rat pituitary tumor cells by enzyme-linked immunocytochemistry
39. Rapid actions of estrogens in GH3/B6 pituitary tumor cells via a plasma membrane version of estrogen receptor-α
40. Interaction between estrogen receptor and Pit-1 protein is influenced by estrogen in pituitary cells
41. Estradiol-induced phosphorylation of serine 118 in the estrogen receptor is independent of p42/p44 mitogen-activated protein kinase
42. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
43. Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor α
44. MCF-7: A human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors
45. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
46. Epidermal growth factor-stimulated tyrosine phosphorylation of caveolin-1