-
1
-
-
0020643403
-
Initiation/promotion versus complete carcinogenicity in the rodent liver
-
Ashby J., Elliott B.M., Lefevre P.A., Styles J., Longstaff E. Initiation/promotion versus complete carcinogenicity in the rodent liver. Environ. Health Perspect. 50:1983;339-346.
-
(1983)
Environ. Health Perspect.
, vol.50
, pp. 339-346
-
-
Ashby, J.1
Elliott, B.M.2
Lefevre, P.A.3
Styles, J.4
Longstaff, E.5
-
2
-
-
84956941706
-
The role of croton oil applications, associated with a single painting of a carcinogen, in tumour induction of the mouse's skin
-
Berenblum I., Shubik P. The role of croton oil applications, associated with a single painting of a carcinogen, in tumour induction of the mouse's skin. Br. J. Cancer. 1:1947;378-382.
-
(1947)
Br. J. Cancer
, vol.1
, pp. 378-382
-
-
Berenblum, I.1
Shubik, P.2
-
3
-
-
0032846010
-
Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants
-
Cook L.S., Goldoft M., Schwartz S.M., Weiss N.S. Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants. J. Urol. 161:1999;152-155.
-
(1999)
J. Urol.
, vol.161
, pp. 152-155
-
-
Cook, L.S.1
Goldoft, M.2
Schwartz, S.M.3
Weiss, N.S.4
-
4
-
-
0034011917
-
Immunohistochemical detection of carcinogen-DNA adducts in normal human prostate tissues transplanted into the subcutis of athymic nude mice: Results with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 3,2′-dimethyl-4-aminobiphenyl (DMAB) and relation to cytochrome P450s and N-acetyltransferase activity
-
Cui L., Takahashi S., Tada M., Kato K., Yamada Y., Kohri K., Shirai T. Immunohistochemical detection of carcinogen-DNA adducts in normal human prostate tissues transplanted into the subcutis of athymic nude mice: results with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 3,2′-dimethyl-4-aminobiphenyl (DMAB) and relation to cytochrome P450s and N-acetyltransferase activity. Jpn. J. Cancer Res. 91:2000;52-58.
-
(2000)
Jpn. J. Cancer Res.
, vol.91
, pp. 52-58
-
-
Cui, L.1
Takahashi, S.2
Tada, M.3
Kato, K.4
Yamada, Y.5
Kohri, K.6
Shirai, T.7
-
5
-
-
0032521538
-
High frequency of β-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat
-
Dashwood R.H., Suzui M., Nakagama H., Sugimura T., Nagao M. High frequency of β-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat. Cancer Res. 58:1998;1127-1129.
-
(1998)
Cancer Res.
, vol.58
, pp. 1127-1129
-
-
Dashwood, R.H.1
Suzui, M.2
Nakagama, H.3
Sugimura, T.4
Nagao, M.5
-
6
-
-
0032970624
-
DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
Dingley K.H., Curtis K.D., Nowell S., Felton J.S., Lang N.P., Turteltaub K.W. DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Cancer Epidemiol. Biomarkers Prev. 8:1999;507-512.
-
(1999)
Cancer Epidemiol. Biomarkers Prev.
, vol.8
, pp. 507-512
-
-
Dingley, K.H.1
Curtis, K.D.2
Nowell, S.3
Felton, J.S.4
Lang, N.P.5
Turteltaub, K.W.6
-
7
-
-
0023017251
-
The isolation and identification of a new mutagen from fried ground beef: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
-
Felton J.S., Knize M.G., Shen N.H., Lewis P.R., Andresen B.D., Happe J., Hatch F.T. The isolation and identification of a new mutagen from fried ground beef: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis. 7:1986;1081-1086.
-
(1986)
Carcinogenesis
, vol.7
, pp. 1081-1086
-
-
Felton, J.S.1
Knize, M.G.2
Shen, N.H.3
Lewis, P.R.4
Andresen, B.D.5
Happe, J.6
Hatch, F.T.7
-
8
-
-
0036119631
-
Chemoprevention of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ) after initiation with 1,2-dimethylhydrazine (DMH) in F344 rats
-
Futakuchi M., Hirose M., Imaida K., Takahashi S., Ogawa K., Asamoto M., Miki T., Shirai T. Chemoprevention of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ) after initiation with 1,2-dimethylhydrazine (DMH) in F344 rats. Carcinogenesis. 23:2002;283-288.
-
(2002)
Carcinogenesis
, vol.23
, pp. 283-288
-
-
Futakuchi, M.1
Hirose, M.2
Imaida, K.3
Takahashi, S.4
Ogawa, K.5
Asamoto, M.6
Miki, T.7
Shirai, T.8
-
9
-
-
0027515243
-
Heterocyclic aromatic amine formation in grilled bacon, beef and fish and grill scrapings
-
Gross G.A., Turesky R.J., Fay L.B., Stillwell W.G., Skipper P.L., Tannenbaum S.R. Heterocyclic aromatic amine formation in grilled bacon, beef and fish and grill scrapings. Carcinogenesis. 14:1993;2313-2318.
-
(1993)
Carcinogenesis
, vol.14
, pp. 2313-2318
-
-
Gross, G.A.1
Turesky, R.J.2
Fay, L.B.3
Stillwell, W.G.4
Skipper, P.L.5
Tannenbaum, S.R.6
-
10
-
-
0027787536
-
Dose dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis in rats
-
Hasegawa R., Sano M., Tamano S., Imaida K., Shirai T., Nagao M., Sugimura T., Ito N. Dose dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis in rats. Carcinogenesis. 14:1993;2553-2557.
-
(1993)
Carcinogenesis
, vol.14
, pp. 2553-2557
-
-
Hasegawa, R.1
Sano, M.2
Tamano, S.3
Imaida, K.4
Shirai, T.5
Nagao, M.6
Sugimura, T.7
Ito, N.8
-
11
-
-
0029857906
-
Dose-dependent induction of mammary carcinomas in female Sprague-Dawley rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
Imaida K., Hagiwara A., Yada H., Masui T., Hasegawa R., Hirose M., Sugimura T., Ito N., Shirai T. Dose-dependent induction of mammary carcinomas in female Sprague-Dawley rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Jpn. J. Cancer Res. 87:1996;1116-1120.
-
(1996)
Jpn. J. Cancer Res.
, vol.87
, pp. 1116-1120
-
-
Imaida, K.1
Hagiwara, A.2
Yada, H.3
Masui, T.4
Hasegawa, R.5
Hirose, M.6
Sugimura, T.7
Ito, N.8
Shirai, T.9
-
12
-
-
0034908168
-
Organ-dependent enhancement of rat 3,2′-dimethyl-4-aminobiphenyl (DMAB) carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Positive effects on the intestine but not the prostate
-
Imaida K., Sano M., Tamano S., Asamoto M., Ogawa K., Futakuchi M., Shirai T. Organ-dependent enhancement of rat 3,2′-dimethyl-4-aminobiphenyl (DMAB) carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): positive effects on the intestine but not the prostate. Carcinogenesis. 22:2001;1295-1299.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1295-1299
-
-
Imaida, K.1
Sano, M.2
Tamano, S.3
Asamoto, M.4
Ogawa, K.5
Futakuchi, M.6
Shirai, T.7
-
13
-
-
15444351785
-
Medium-term rat liver bioassay for rapid detection of hepatocarcinogenic substances
-
Ito N., Hasegawa R., Imaida K., Hirose M., Shirai T., Tamano S., Hagiwara A. Medium-term rat liver bioassay for rapid detection of hepatocarcinogenic substances. J. Toxicol. Pathol. 10:1997;1-11.
-
(1997)
J. Toxicol. Pathol.
, vol.10
, pp. 1-11
-
-
Ito, N.1
Hasegawa, R.2
Imaida, K.3
Hirose, M.4
Shirai, T.5
Tamano, S.6
Hagiwara, A.7
-
14
-
-
0025768966
-
A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
-
Ito N., Hasegawa R., Sano M., Tamano S., Esumi H., Takayama S., Sugimura T. A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis. 12:1991;1503-1506.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1503-1506
-
-
Ito, N.1
Hasegawa, R.2
Sano, M.3
Tamano, S.4
Esumi, H.5
Takayama, S.6
Sugimura, T.7
-
15
-
-
0023730851
-
Variation in tumor yield in the prostate and other target organs of the rat in response to varied dosage and duration of administration of 3,2′-dimethyl-4-aminobiphenyl
-
Ito N., Shirai T., Tagawa Y., Nakamura A., Fukushima S. Variation in tumor yield in the prostate and other target organs of the rat in response to varied dosage and duration of administration of 3,2′-dimethyl-4-aminobiphenyl. Cancer Res. 48:1988;4629-4632.
-
(1988)
Cancer Res.
, vol.48
, pp. 4629-4632
-
-
Ito, N.1
Shirai, T.2
Tagawa, Y.3
Nakamura, A.4
Fukushima, S.5
-
16
-
-
85047691659
-
Sequential observation of pathomorphologic alterations in preneoplastic lesions during the promoting stage of hepatocarcinogenesis and the development of short-term test system for hepatopromoters and hepatocarcinogens
-
Ito N., Tsuda H., Hasegawa R., Imaida K. Sequential observation of pathomorphologic alterations in preneoplastic lesions during the promoting stage of hepatocarcinogenesis and the development of short-term test system for hepatopromoters and hepatocarcinogens. Toxicol. Pathol. 10:1982;37-49.
-
(1982)
Toxicol. Pathol.
, vol.10
, pp. 37-49
-
-
Ito, N.1
Tsuda, H.2
Hasegawa, R.3
Imaida, K.4
-
17
-
-
0020606326
-
Absence of a complete carcinogenic effect of phenacetin on the quiescent
-
Kunze E., Woltjen H.H., Albrecht H. Absence of a complete carcinogenic effect of phenacetin on the quiescent. Urol. Int. 38:1983;223-228.
-
(1983)
Urol. Int.
, vol.38
, pp. 223-228
-
-
Kunze, E.1
Woltjen, H.H.2
Albrecht, H.3
-
18
-
-
0034695041
-
Analysis of DNA adducts by accelerator mass spectrometry in human breast tissue after administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and benzo[a]pyrene
-
Lightfoot T.J., Coxhead J.M., Cupid B.C., Nicholson S., Garner R.C. Analysis of DNA adducts by accelerator mass spectrometry in human breast tissue after administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and benzo[a]pyrene. Mutat. Res. 472:2000;119-127.
-
(2000)
Mutat. Res.
, vol.472
, pp. 119-127
-
-
Lightfoot, T.J.1
Coxhead, J.M.2
Cupid, B.C.3
Nicholson, S.4
Garner, R.C.5
-
19
-
-
0034695188
-
Increased susceptibility of adult rats to azoxymethane-induced aberrant crypt foci
-
Magnuson B.A., South E.H., Exon J.H., Dashwood R.H., Xu M., Hendrix K., Hubele S. Increased susceptibility of adult rats to azoxymethane-induced aberrant crypt foci. Cancer Lett. 161:2000;185-193.
-
(2000)
Cancer Lett.
, vol.161
, pp. 185-193
-
-
Magnuson, B.A.1
South, E.H.2
Exon, J.H.3
Dashwood, R.H.4
Xu, M.5
Hendrix, K.6
Hubele, S.7
-
20
-
-
0032512693
-
Modification by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) of 3,2′-dimethyl-4-aminobiphenyl (DMAB)-induced rat pancreatic and intestinal tumorigenesis
-
Ogawa K., Iwasaki S., Esumi H., Fukushima S., Shirai T. Modification by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) of 3,2′-dimethyl-4-aminobiphenyl (DMAB)-induced rat pancreatic and intestinal tumorigenesis. Cancer Lett. 124:1998;31-37.
-
(1998)
Cancer Lett.
, vol.124
, pp. 31-37
-
-
Ogawa, K.1
Iwasaki, S.2
Esumi, H.3
Fukushima, S.4
Shirai, T.5
-
21
-
-
0032783506
-
Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat prostate and induction of invasive carcinomas by subsequent treatment with testosterone propionate
-
Shirai T., Cui L., Takahashi S., Futakuchi M., Asamoto M., Kato K., Ito N. Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat prostate and induction of invasive carcinomas by subsequent treatment with testosterone propionate. Cancer Lett. 143:1999;217-221.
-
(1999)
Cancer Lett.
, vol.143
, pp. 217-221
-
-
Shirai, T.1
Cui, L.2
Takahashi, S.3
Futakuchi, M.4
Asamoto, M.5
Kato, K.6
Ito, N.7
-
22
-
-
0025875813
-
Selective induction of rat urinary bladder tumors by simultaneous administration of 3,2′-dimethyl-4-aminobiphenyl (DMAB) and butylated hydroxyanisole or butylated hydroxytoluene is associated with increased DMAB-DNA adduct formation
-
Shirai T., Fukushima S., Kawabe M., Shibata M.-A., Iwasaki S., Tada M., Ito N. Selective induction of rat urinary bladder tumors by simultaneous administration of 3,2′-dimethyl-4-aminobiphenyl (DMAB) and butylated hydroxyanisole or butylated hydroxytoluene is associated with increased DMAB-DNA adduct formation. Carcinogenesis. 12:1991;1335-1339.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1335-1339
-
-
Shirai, T.1
Fukushima, S.2
Kawabe, M.3
Shibata, M.-A.4
Iwasaki, S.5
Tada, M.6
Ito, N.7
-
23
-
-
0025230787
-
Immunohistochemical demonstration of carcinogen-DNA adducts in target and non-target tissues of rats given a prostate carcinogen, 3,2′-dimethyl-4-aminobiphenyl
-
Shirai T., Nakamura A., Fukushima S., Tada M., Morita T., Ito N. Immunohistochemical demonstration of carcinogen-DNA adducts in target and non-target tissues of rats given a prostate carcinogen, 3,2′-dimethyl-4-aminobiphenyl. Carcinogenesis. 11:1990;653-657.
-
(1990)
Carcinogenesis
, vol.11
, pp. 653-657
-
-
Shirai, T.1
Nakamura, A.2
Fukushima, S.3
Tada, M.4
Morita, T.5
Ito, N.6
-
24
-
-
0022385995
-
Rat prostate as one of the target organs for 3,2′-dimethyl-4-aminobiphenyl-induced carcinogenesis: Effects of dietary ethinyl estradiol and methyltestosterone
-
Shirai T., Sakata T., Fukushima S., Ikawa E., Ito N. Rat prostate as one of the target organs for 3,2′-dimethyl-4-aminobiphenyl-induced carcinogenesis: effects of dietary ethinyl estradiol and methyltestosterone. Jpn. J. Cancer Res. (Gann). 76:1985;803-808.
-
(1985)
Jpn. J. Cancer Res. (Gann)
, vol.76
, pp. 803-808
-
-
Shirai, T.1
Sakata, T.2
Fukushima, S.3
Ikawa, E.4
Ito, N.5
-
25
-
-
14444288520
-
The prostate: A target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods
-
Shirai T., Sano M., Tamano S., Takahashi S., Hirose M., Futakuchi M., Hasegawa R., Imaida K., Matsumoto K., Wakabayashi K., Sugimura T., Ito N. The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods. Cancer Res. 57:1997;195-198.
-
(1997)
Cancer Res.
, vol.57
, pp. 195-198
-
-
Shirai, T.1
Sano, M.2
Tamano, S.3
Takahashi, S.4
Hirose, M.5
Futakuchi, M.6
Hasegawa, R.7
Imaida, K.8
Matsumoto, K.9
Wakabayashi, K.10
Sugimura, T.11
Ito, N.12
-
26
-
-
0027970027
-
DNA adducts in target and non-target tissues of 3,2′-dimethyl-4-aminobiphenyl in rats
-
Shirai T., Tada M., Kojima M., Hasegawa R., Masui T., Ito N. DNA adducts in target and non-target tissues of 3,2′-dimethyl-4-aminobiphenyl in rats. Environ. Health Perspect. 102:1994;167-172.
-
(1994)
Environ. Health Perspect.
, vol.102
, pp. 167-172
-
-
Shirai, T.1
Tada, M.2
Kojima, M.3
Hasegawa, R.4
Masui, T.5
Ito, N.6
-
27
-
-
17444448902
-
Use of polyclonal antibodies against carcinogen-DNA adducts in analysis of carcinogenesis
-
Shirai T., Takahashi S., Cui L., Yamada Y., Tada M., Kadlubar F.F., Ito N. Use of polyclonal antibodies against carcinogen-DNA adducts in analysis of carcinogenesis. Toxicol. Lett. 102/103:1998;441-446.
-
(1998)
Toxicol. Lett.
, vol.102-103
, pp. 441-446
-
-
Shirai, T.1
Takahashi, S.2
Cui, L.3
Yamada, Y.4
Tada, M.5
Kadlubar, F.F.6
Ito, N.7
-
28
-
-
0034674913
-
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk
-
Sinha R., Gustafson D.R., Kulldorff M., Wen W.Q., Cerhan J.R., Zheng W. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk. J. Natl. Cancer Inst. 92:2000;1352-1354.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1352-1354
-
-
Sinha, R.1
Gustafson, D.R.2
Kulldorff, M.3
Wen, W.Q.4
Cerhan, J.R.5
Zheng, W.6
-
29
-
-
0026049512
-
Heterocyclic amines: New mutagens and carcinogens in cooked foods
-
Sugimura T., Wakabayashi K. Heterocyclic amines: new mutagens and carcinogens in cooked foods. Adv. Exp. Med. Biol. 283:1991;569-578.
-
(1991)
Adv. Exp. Med. Biol.
, vol.283
, pp. 569-578
-
-
Sugimura, T.1
Wakabayashi, K.2
-
30
-
-
17044456908
-
Immunohistochemical demonstration of carcinogen-DNA adducts in tissues of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Detection in paraffin-embedded sections and tissue distribution
-
Takahashi S., Tamano S., Hirose M., Kimoto N., Ikeda Y., Sakakibara M., Tada M., Kadlubar F.F., Ito N., Shirai T. Immunohistochemical demonstration of carcinogen-DNA adducts in tissues of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): detection in paraffin-embedded sections and tissue distribution. Cancer Res. 58:1998;4307-4313.
-
(1998)
Cancer Res.
, vol.58
, pp. 4307-4313
-
-
Takahashi, S.1
Tamano, S.2
Hirose, M.3
Kimoto, N.4
Ikeda, Y.5
Sakakibara, M.6
Tada, M.7
Kadlubar, F.F.8
Ito, N.9
Shirai, T.10
-
31
-
-
0033860988
-
More frequent β-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats
-
Tsukamoto T., Tanaka H., Fukami H., Inoue M., Takahashi M., Wakabayashi K., Tatematsu M. More frequent β-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats. Jpn. J. Cancer Res. 91:2000;792-796.
-
(2000)
Jpn. J. Cancer Res.
, vol.91
, pp. 792-796
-
-
Tsukamoto, T.1
Tanaka, H.2
Fukami, H.3
Inoue, M.4
Takahashi, M.5
Wakabayashi, K.6
Tatematsu, M.7
-
32
-
-
0025739669
-
Presence of carcinogenic heterocyclic amines in urine of healthy volunteers eating normal diet, but not in patients receiving parenteral alimentation
-
Ushiyama H., Wakabayashi K., Hirose M., Itoh H., Sugimura T., Nagao M. Presence of carcinogenic heterocyclic amines in urine of healthy volunteers eating normal diet, but not in patients receiving parenteral alimentation. Carcinogenesis. 12:1991;1417-1422.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1417-1422
-
-
Ushiyama, H.1
Wakabayashi, K.2
Hirose, M.3
Itoh, H.4
Sugimura, T.5
Nagao, M.6
-
33
-
-
0027193044
-
Exposure to heterocyclic amines
-
Wakabayashi K., Ushijima H., Takahashi M., Nukaya H., Kim S.-B., Hirose M., Ochiai M., Sugimura T., Nagao M. Exposure to heterocyclic amines. Environ. Health Perspect. 99:1993;129-133.
-
(1993)
Environ. Health Perspect.
, vol.99
, pp. 129-133
-
-
Wakabayashi, K.1
Ushijima, H.2
Takahashi, M.3
Nukaya, H.4
Kim, S.-B.5
Hirose, M.6
Ochiai, M.7
Sugimura, T.8
Nagao, M.9
|