-
1
-
-
0028179236
-
A single species of A1 adenosine receptor expressed in Chinese hamster ovary cells not only inhibits cAMP accumulation but also stimulates phospholipase C and arachidonate release
-
Akbar M, Okajima F, Tomura H, Shimegi S, Kondo Y. A single species of A1 adenosine receptor expressed in Chinese hamster ovary cells not only inhibits cAMP accumulation but also stimulates phospholipase C and arachidonate release. Mol Pharmacol 45: 1036-1042, 1994.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 1036-1042
-
-
Akbar, M.1
Okajima, F.2
Tomura, H.3
Shimegi, S.4
Kondo, Y.5
-
2
-
-
0023925324
-
Occurrence and developmental pattern of neuromedin U-immunoreactive nerves in the gastrointestinal tract and brain of the rat
-
Ballesta J, Carlei F, Bishop AE, Steel JH, Gibson SJ, Fahey M, Hennessey R, Domin J, Bloom SR, Polak JM. Occurrence and developmental pattern of neuromedin U-immunoreactive nerves in the gastrointestinal tract and brain of the rat. Neuroscience 25: 797-816, 1988.
-
(1988)
Neuroscience
, vol.25
, pp. 797-816
-
-
Ballesta, J.1
Carlei, F.2
Bishop, A.E.3
Steel, J.H.4
Gibson, S.J.5
Fahey, M.6
Hennessey, R.7
Domin, J.8
Bloom, S.R.9
Polak, J.M.10
-
3
-
-
1842299315
-
Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit
-
Bence K, Ma W, Kozasa T, Huang XY. Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit. Nature 389: 296-299, 1997.
-
(1997)
Nature
, vol.389
, pp. 296-299
-
-
Bence, K.1
Ma, W.2
Kozasa, T.3
Huang, X.Y.4
-
4
-
-
0031815337
-
Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: Evidence for agonist-directed trafficking of receptor stimulus
-
Berg KA, Maayani S, Goldfarb J, Scaramellini C, Leff P, Clarke WP. Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus. Mol Pharmacol 54: 94-104, 1998.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 94-104
-
-
Berg, K.A.1
Maayani, S.2
Goldfarb, J.3
Scaramellini, C.4
Leff, P.5
Clarke, W.P.6
-
5
-
-
0033118334
-
Molecular tinkering of G protein-coupled receptors: An evolutionary success
-
Bockaert J, Pin JP. Molecular tinkering of G protein-coupled receptors: an evolutionary success. EMBO J 18: 1723-1729, 1999.
-
(1999)
EMBO J
, vol.18
, pp. 1723-1729
-
-
Bockaert, J.1
Pin, J.P.2
-
6
-
-
2642553111
-
Neuromedin U and its receptors: Structure, function, and physiological roles
-
Brighton PJ, Szekeres PG, Willars GB. Neuromedin U and its receptors: structure, function, and physiological roles. Pharmacol Rev 56: 231-248, 2004.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 231-248
-
-
Brighton, P.J.1
Szekeres, P.G.2
Willars, G.B.3
-
7
-
-
0347949548
-
Insights into G protein structure, function, and regulation
-
Cabrera-Vera TM, Vanhauwe J, Thomas TO, Medkova M, Preininger A, Mazzoni MR, Hamm HE. Insights into G protein structure, function, and regulation. Endocr Rev 24: 765-781, 2003.
-
(2003)
Endocr Rev
, vol.24
, pp. 765-781
-
-
Cabrera-Vera, T.M.1
Vanhauwe, J.2
Thomas, T.O.3
Medkova, M.4
Preininger, A.5
Mazzoni, M.R.6
Hamm, H.E.7
-
8
-
-
0027245830
-
Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha
-
Conklin BR, Farfel Z, Lustig KD, Julius D, Bourne HR. Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha. Nature 363: 274-276, 1993.
-
(1993)
Nature
, vol.363
, pp. 274-276
-
-
Conklin, B.R.1
Farfel, Z.2
Lustig, K.D.3
Julius, D.4
Bourne, H.R.5
-
9
-
-
0029957669
-
Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation
-
Conklin BR, Herzmark P, Ishida S, Voyno-Yasenetskaya TA, Sun Y, Farfel Z, Bourne HR. Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation. Mol Pharmacol 50: 885-890, 1996.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 885-890
-
-
Conklin, B.R.1
Herzmark, P.2
Ishida, S.3
Voyno-Yasenetskaya, T.A.4
Sun, Y.5
Farfel, Z.6
Bourne, H.R.7
-
10
-
-
34247615526
-
A1 adenosine receptor partial agonist lowers plasma FFA and improves insulin resistance induced by high-fat diet in rodents
-
Dhalla AK, Wong MY, Voshol PJ, Belardinelli L, Reaven GM. A1 adenosine receptor partial agonist lowers plasma FFA and improves insulin resistance induced by high-fat diet in rodents. Am J Physiol Endocrinol Metab 292: E1358-E1363, 2007.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Dhalla, A.K.1
Wong, M.Y.2
Voshol, P.J.3
Belardinelli, L.4
Reaven, G.M.5
-
11
-
-
18744376919
-
Real-time monitoring of receptor and G-protein interactions in living cells
-
Gales C, Rebois RV, Hogue M, Trieu P, Breit A, Hebert TE, Bouvier M. Real-time monitoring of receptor and G-protein interactions in living cells. Nat Methods 2: 177-184, 2005.
-
(2005)
Nat Methods
, vol.2
, pp. 177-184
-
-
Gales, C.1
Rebois, R.V.2
Hogue, M.3
Trieu, P.4
Breit, A.5
Hebert, T.E.6
Bouvier, M.7
-
12
-
-
0037154571
-
Regulation of glycogen metabolism in hepatocytes through adenosine receptors. Role of Ca2+ and cAMP
-
Gonzalez-Benitez E, Guinzberg R, Diaz-Cruz A, Pina E. Regulation of glycogen metabolism in hepatocytes through adenosine receptors. Role of Ca2+ and cAMP. Eur J Pharmacol 437: 105-111, 2002.
-
(2002)
Eur J Pharmacol
, vol.437
, pp. 105-111
-
-
Gonzalez-Benitez, E.1
Guinzberg, R.2
Diaz-Cruz, A.3
Pina, E.4
-
14
-
-
20844434337
-
A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells
-
Hoffmann C, Gaietta G, Bunemann M, Adams SR, Oberdorff-Maass S, Behr B, Vilardaga JP, Tsien RY, Ellisman MH, Lohse MJ. A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells. Nat Methods 2: 171-176, 2005.
-
(2005)
Nat Methods
, vol.2
, pp. 171-176
-
-
Hoffmann, C.1
Gaietta, G.2
Bunemann, M.3
Adams, S.R.4
Oberdorff-Maass, S.5
Behr, B.6
Vilardaga, J.P.7
Tsien, R.Y.8
Ellisman, M.H.9
Lohse, M.J.10
-
15
-
-
0023607068
-
Topographic localization of neuromedin U-like structures in the rat brain: An immunohistochemical study
-
Honzawa M, Sudoh T, Minamino N, Tohyama M, Matsuo H. Topographic localization of neuromedin U-like structures in the rat brain: an immunohistochemical study. Neuroscience 23: 1103-1122, 1987.
-
(1987)
Neuroscience
, vol.23
, pp. 1103-1122
-
-
Honzawa, M.1
Sudoh, T.2
Minamino, N.3
Tohyama, M.4
Matsuo, H.5
-
16
-
-
0034612519
-
Identification of receptors for neuromedin U and its role in feeding
-
Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, Williams DL Jr, Feighner SD, Nunes CN, Murphy B, Stair JN, Yu H, Jiang Q, Clements MK, Tan CP, McKee KK, Hreniuk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q. Identification of receptors for neuromedin U and its role in feeding. Nature 406: 70-74, 2000.
-
(2000)
Nature
, vol.406
, pp. 70-74
-
-
Howard, A.D.1
Wang, R.2
Pong, S.S.3
Mellin, T.N.4
Strack, A.5
Guan, X.M.6
Zeng, Z.7
Williams Jr, D.L.8
Feighner, S.D.9
Nunes, C.N.10
Murphy, B.11
Stair, J.N.12
Yu, H.13
Jiang, Q.14
Clements, M.K.15
Tan, C.P.16
McKee, K.K.17
Hreniuk, D.L.18
McDonald, T.P.19
Lynch, K.R.20
Evans, J.F.21
Austin, C.P.22
Caskey, C.T.23
Van der Ploeg, L.H.24
Liu, Q.25
more..
-
17
-
-
3042648805
-
A(1) adenosine receptor agonists: Medicinal chemistry and therapeutic potential
-
Hutchinson SA, Scammells PJ. A(1) adenosine receptor agonists: medicinal chemistry and therapeutic potential. Curr Pharm Des 10: 2021-2039, 2004.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 2021-2039
-
-
Hutchinson, S.A.1
Scammells, P.J.2
-
18
-
-
0029054965
-
Agonist-receptor efficacy. II. Agonist trafficking of receptor signals
-
Kenakin T. Agonist-receptor efficacy. II. Agonist trafficking of receptor signals. Trends Pharmacol Sci 16: 232-238, 1995.
-
(1995)
Trends Pharmacol Sci
, vol.16
, pp. 232-238
-
-
Kenakin, T.1
-
19
-
-
27144434813
-
Techniques: Promiscuous Galpha proteins in basic research and drug discovery
-
Kostenis E, Waelbroeck M, Milligan G. Techniques: promiscuous Galpha proteins in basic research and drug discovery. Trends Pharmacol Sci 26: 595-602, 2005.
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 595-602
-
-
Kostenis, E.1
Waelbroeck, M.2
Milligan, G.3
-
20
-
-
0025765580
-
The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor
-
Libert F, Schiffmann SN, Lefort A, Parmentier M, Gerard C, Dumont JE, Vanderhaeghen JJ, Vassart G. The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor. EMBO J 10: 1677-1682, 1991.
-
(1991)
EMBO J
, vol.10
, pp. 1677-1682
-
-
Libert, F.1
Schiffmann, S.N.2
Lefort, A.3
Parmentier, M.4
Gerard, C.5
Dumont, J.E.6
Vanderhaeghen, J.J.7
Vassart, G.8
-
21
-
-
11144230328
-
G16-mediated activation of nuclear factor kappaB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling
-
Liu AM, Wong YH. G16-mediated activation of nuclear factor kappaB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling. J Biol Chem 279: 53196-53204, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 53196-53204
-
-
Liu, A.M.1
Wong, Y.H.2
-
22
-
-
0031741567
-
Activation of various subtypes of G-protein alpha subunits by partial agonists of the adenosine A1 receptor
-
Lorenzen A, Lang H, Schwabe U. Activation of various subtypes of G-protein alpha subunits by partial agonists of the adenosine A1 receptor. Biochem Pharmacol 56: 1287-1293, 1998.
-
(1998)
Biochem Pharmacol
, vol.56
, pp. 1287-1293
-
-
Lorenzen, A.1
Lang, H.2
Schwabe, U.3
-
23
-
-
3442882187
-
Paracrine regulation of ovarian granulosa cell differentiation by stanniocalcin (STC) 1: Mediation through specific STC1 receptors
-
Luo CW, Kawamura K, Klein C, Hsueh AJ. Paracrine regulation of ovarian granulosa cell differentiation by stanniocalcin (STC) 1: mediation through specific STC1 receptors. Mol Endocrinol 18: 2085-2096, 2004.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2085-2096
-
-
Luo, C.W.1
Kawamura, K.2
Klein, C.3
Hsueh, A.J.4
-
24
-
-
21644449969
-
Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1
-
McLaughlin JN, Shen L, Holinstat M, Brooks JD, Dibenedetto E, Hamm HE. Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1. J Biol Chem 280: 25048-25059, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 25048-25059
-
-
McLaughlin, J.N.1
Shen, L.2
Holinstat, M.3
Brooks, J.D.4
Dibenedetto, E.5
Hamm, H.E.6
-
25
-
-
0022392038
-
Neuromedins: Novel smooth-muscle stimulating peptides identified in porcine spinal cord
-
Minamino N, Sudoh T, Kangawa K, Matsuo H. Neuromedins: novel smooth-muscle stimulating peptides identified in porcine spinal cord. Peptides 6, Suppl 3: 245-248, 1985.
-
(1985)
Peptides
, vol.6
, Issue.SUPPL. 3
, pp. 245-248
-
-
Minamino, N.1
Sudoh, T.2
Kangawa, K.3
Matsuo, H.4
-
26
-
-
0033621596
-
Incorporation of Galpha(z)-specific sequence at the carboxyl terminus increases the promiscuity of Galpha(16) toward G(i)-coupled receptors
-
Mody SM, Ho MK, Joshi SA, Wong YH. Incorporation of Galpha(z)-specific sequence at the carboxyl terminus increases the promiscuity of Galpha(16) toward G(i)-coupled receptors. Mol Pharmacol 57: 13-23, 2000.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 13-23
-
-
Mody, S.M.1
Ho, M.K.2
Joshi, S.A.3
Wong, Y.H.4
-
27
-
-
13444303901
-
Identification of neuromedin S and its possible role in the mammalian circadian oscillator system
-
Mori K, Miyazato M, Ida T, Murakami N, Serino R, Ueta Y, Kojima M, Kangawa K. Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J 24: 325-335, 2005.
-
(2005)
EMBO J
, vol.24
, pp. 325-335
-
-
Mori, K.1
Miyazato, M.2
Ida, T.3
Murakami, N.4
Serino, R.5
Ueta, Y.6
Kojima, M.7
Kangawa, K.8
-
28
-
-
0028983403
-
Adenosine A1 receptor-mediated activation of phospholipase C-beta 3 in intestinal muscle: Dual requirement for alpha and beta gamma subunits of Gi3
-
Murthy KS, Makhlouf GM. Adenosine A1 receptor-mediated activation of phospholipase C-beta 3 in intestinal muscle: dual requirement for alpha and beta gamma subunits of Gi3. Mol Pharmacol 47: 1172-1179, 1995.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1172-1179
-
-
Murthy, K.S.1
Makhlouf, G.M.2
-
30
-
-
0028179510
-
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets
-
Offermanns S, Laugwitz KL, Spicher K, Schultz G. G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proc Natl Acad Sci USA 91: 504-508, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 504-508
-
-
Offermanns, S.1
Laugwitz, K.L.2
Spicher, K.3
Schultz, G.4
-
32
-
-
1542320537
-
G protein signaling: Insights from new structures
-
Preininger AM, Hamm HE. G protein signaling: insights from new structures. Sci STKE 2004: re3, 2004.
-
(2004)
Sci STKE
, vol.2004
-
-
Preininger, A.M.1
Hamm, H.E.2
-
33
-
-
0034693142
-
Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system
-
Raddatz R, Wilson AE, Artymyshyn R, Bonini JA, Borowsky B, Boteju LW, Zhou S, Kouranova EV, Nagorny R, Guevarra MS, Dai M, Lerman GS, Vaysse PJ, Branchek TA, Gerald C, Forray C, Adham N. Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system. J Biol Chem 275: 32452-32459, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 32452-32459
-
-
Raddatz, R.1
Wilson, A.E.2
Artymyshyn, R.3
Bonini, J.A.4
Borowsky, B.5
Boteju, L.W.6
Zhou, S.7
Kouranova, E.V.8
Nagorny, R.9
Guevarra, M.S.10
Dai, M.11
Lerman, G.S.12
Vaysse, P.J.13
Branchek, T.A.14
Gerald, C.15
Forray, C.16
Adham, N.17
-
34
-
-
0028786343
-
Purinergic inhibition of neurotransmitter release in the central nervous system
-
Ribeiro JA. Purinergic inhibition of neurotransmitter release in the central nervous system. Pharmacol Toxicol 77: 299-305, 1995.
-
(1995)
Pharmacol Toxicol
, vol.77
, pp. 299-305
-
-
Ribeiro, J.A.1
-
35
-
-
0028348690
-
Agonist-specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messenger systems
-
Robb S, Cheek TR, Hannan FL, Hall LM, Midgley JM, Evans PD. Agonist-specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messenger systems. EMBO J 13: 1325-1330, 1994.
-
(1994)
EMBO J
, vol.13
, pp. 1325-1330
-
-
Robb, S.1
Cheek, T.R.2
Hannan, F.L.3
Hall, L.M.4
Midgley, J.M.5
Evans, P.D.6
-
36
-
-
0034035477
-
The role of Rho in G protein-coupled receptor signal transduction
-
Sah VP, Seasholtz TM, Sagi SA, Brown JH. The role of Rho in G protein-coupled receptor signal transduction. Annu Rev Pharmacol Toxicol 40: 459-489, 2000.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 459-489
-
-
Sah, V.P.1
Seasholtz, T.M.2
Sagi, S.A.3
Brown, J.H.4
-
37
-
-
0028027596
-
GTPase mechanism of G proteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4
-
Sondek J, Lambright DG, Noel JP, Hamm HE, Sigler PB. GTPase mechanism of G proteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4. Nature 372: 276-279, 1994.
-
(1994)
Nature
, vol.372
, pp. 276-279
-
-
Sondek, J.1
Lambright, D.G.2
Noel, J.P.3
Hamm, H.E.4
Sigler, P.B.5
-
38
-
-
0035828982
-
A1 adenosine receptor activation inhibits neurite process formation by Rho kinase-mediated pathways
-
Thevananther S, Rivera A, Rivkees SA. A1 adenosine receptor activation inhibits neurite process formation by Rho kinase-mediated pathways. Neuroreport 12: 3057-3063, 2001.
-
(2001)
Neuroreport
, vol.12
, pp. 3057-3063
-
-
Thevananther, S.1
Rivera, A.2
Rivkees, S.A.3
-
39
-
-
0037446894
-
The G protein-coupled receptor repertoires of human and mouse
-
Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA. The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci USA 100: 4903-4908, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4903-4908
-
-
Vassilatis, D.K.1
Hohmann, J.G.2
Zeng, H.3
Li, F.4
Ranchalis, J.E.5
Mortrud, M.T.6
Brown, A.7
Rodriguez, S.S.8
Weller, J.R.9
Wright, A.C.10
Bergmann, J.E.11
Gaitanaris, G.A.12
-
40
-
-
0022347238
-
Pertussis toxin-catalyzed ADP-ribosylation of transducin cysteine 347 is the ADP-ribose acceptor site
-
West RE Jr, Moss J, Vaughan M, Liu T, Liu TY. Pertussis toxin-catalyzed ADP-ribosylation of transducin cysteine 347 is the ADP-ribose acceptor site. J Biol Chem 260: 14428-14430, 1985.
-
(1985)
J Biol Chem
, vol.260
, pp. 14428-14430
-
-
West Jr, R.E.1
Moss, J.2
Vaughan, M.3
Liu, T.4
Liu, T.Y.5
-
41
-
-
0038697483
-
Development of a high-throughput bioassay to screen melatonin receptor agonists using human melatonin receptor expressing CHO cells
-
Yokoyama T, Kato N, Yamada N. Development of a high-throughput bioassay to screen melatonin receptor agonists using human melatonin receptor expressing CHO cells. Neurosci Lett 344: 45-48, 2003.
-
(2003)
Neurosci Lett
, vol.344
, pp. 45-48
-
-
Yokoyama, T.1
Kato, N.2
Yamada, N.3
-
42
-
-
27744600963
-
Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake
-
Zhang VJ, Ren PG, Avsian-Kretchmer O, Luo CW, Rauch R, Klein C, Hsueh AJ. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 310: 996-999, 2005.
-
(2005)
Science
, vol.310
, pp. 996-999
-
-
Zhang, V.J.1
Ren, P.G.2
Avsian-Kretchmer, O.3
Luo, C.W.4
Rauch, R.5
Klein, C.6
Hsueh, A.J.7
|