Lactoferrin: Industrial production and applications;Lactoferrina: Producción industrial y aplicaciones

Revista Mexicana de Ciencias Farmaceuticas

Volumn 38, Issue 3, 2007, Pages 30-38

  Serrano, Maria Elisa Drago ^a  

^a DEPARTAMENTO DE SISTEMAS BIOLÓGICOS   (Mexico)

Author keywords

Antimicrobial and anti inflammatory agents; Nutraceuticals; Recombinant lactoferrin

Indexed keywords

AGENNIX; GLYCOPROTEIN; IRON BINDING PROTEIN; LACTOFERRIN; RECOMBINANT LACTOFERRIN; RECOMBINANT PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG;

CANCER RESEARCH; CLINICAL RESEARCH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DIABETIC FOOT; FOOD PRESERVATION; HUMAN; KIDNEY CARCINOMA; PROTEIN BINDING; PROTEIN EXPRESSION; REVIEW; SEPSIS;

EID: 34948900976     PISSN: 10273956     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (60)

1. Lönnerdal B., Iyer S. 1995. Lactoferrin: molecular structure and biological function. Annual Reviews of Nutrition, 15(7): 93-110.
2. Baker H. M., Baker E.N. 2004. Lactoferrin and iron: structural and dynamic aspects of binding and release. Biometals, 17(3):209-216.
3. Levay P.F., Viljoen M. 1995. Lactoferrin: A general review. Haematologica, 80(3): 252-267.
4. Orsi N. 2004. The antimicrobial activity of lactoferrin: current status and perspectives. Biometals, 17(3):189-196.
5. Yamauchi K., Wakabayashi H., Shin K., Takase M. 2006. Bovine lactoferrin: benefits and mechanisms of action against infections. Biochemistry and Cell Biology, 84(3): 291-296.
6. Legrand D., Elass E., Carpentier M., Mazurier J. 2005. Lactoferrin: a modulator of immune and inflammatory responses. Cellular Molecular Life Sciences, 62 (22): 2549-2559.
7. Naidu A.S. 2000. Lactoferrin: natural, multifunctional, antimicrobial. Boca Ratón, Florida, CRC Press.
8. Cornish J., Palmano K., Callon K.E., Watson M., Lin J.M., Valenti P., Naot D., Grey A.B., Reid I.R. 2006. Lactoferrin and bone; structure-activity relationships. Biochemistry and Cell Biology, 84(3): 297-302.
9. Zhang P., Sawicki V., Lewis A., Hanson L., Nuijens J.H., Neville M.C. 2001. Human lactoferrin in milk of transgenic mice increases growth in ten day old suckling neonates. Advances in Experimental Medicine and Biology, 501: 107-113.
10. Weinberg E.D. 2006. Therapeutic potential of iron chelators in diseases associates with iron mismanagement. Journal of Pharmacy and Pharmacology, 58(5):575-584.
11. Weinberg E.D. 2001. Human lactoferrin: a novel therapeutic with broad spectrum potential. Journal of Pharmacy and Pharmacology, 53(10): 1303-1310.
12. Ward P.P., Cunningham G.A., Conneely O.M. 1997. Commercial production of lactoferrin, a multifunctional iron-binding glycoprotein. Biotechnology and Genetic Engeenering Reviews, 14:303-319.
13. Severin S., Wenshui X. 2005. Milk biologically active components as nutraceuticals: review. Critical Reviews in Food Science and Nutrition, 45(7-8):645-656.
14. Ling J.M., Schryvers A.B. 2006. Perspectives on interactions between lactoferrin and bacteria. Biochemistry and Cell Biology, 84(3): 275-281.
15. Singh P.K, Parsek M.R., Greenberg E.P., Welsh M.J. 2002. A component of innate immunity prevents bacterial biofilm development. Nature, 417(6888): 552-555.
16. Berlutti F., Ajello M., Bosso P., Morea C., Petrucca A., Antonini G., Valenti P. 2004. Both lactoferrin and iron influence aggregation and biofilm formation in Streptococcus mutans. Biometals, 17(3): 271-278.
17. Rogan M.P., Taggart C.C., Greene C.M., Murphy P.G., O'Neill S.J., McElvaney N.G. 2004. Loss of microbicidal activity and increased formation of biolm due to decreased lactoferrin activity in patients with cystic fibrosis. The Journal of Infectious Diseases, 190 (7): 1245.1253.
18. Pierre J.L., Fontecave M., Crichton R.R. 2002. Chemistry for an essential biological process: the reduction of ferric ion. Biometals, 15(4):341-346.
19. Raghuveer T.S., McGuire E.M., Martin S.M., Wagner B.A., Rebouche C.J., Buettner G.R., Widness J.A. 2002. Lactoferrin in the preterm infants' diet attenuates iron induced oxidation products. Pediatric Research, 52(6): 964-972.
20. Satué-Gracia M.T., Frankel E.N., Rangavajhyala N., German B. 2000. Lactoferrin in infant formulas: effect of oxidation. Journal of Agriculture and Food Chemistry, 48(10):4984-4990.
21. Nibbering P.H., Ravensbergen E., Welling M.M., van Berkel L.A., van Berkel P.H.C., Pauwels E.K.J., Nuijens J.H. 2001. Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic resistant bacteria. Infection and Immunity, 69(3): 1469-1476.
22. Ohashi A., Murata E., Yamamoto K., Majima E., Sano E., Le Q.T., Katunuma N. 2003. New functions of lactoferrin and β-casein in mammalian milk as cysteine protease inhibitors. Biochemical and Biophysical Research Communications, 306(1): 98-103.
23. Gifford J.L., Hunter H.N., Vogel H.J. 2005. Lactoferricin: a lactoferrin derived peptide with antimicrobial, antiviral, antitumor and immunological properties. Cellular and Molecular Life Sciences, 62(22): 2588-2598.
24. Vorland L.H., Ulvatne H., Andersen J., Haukland H., Rekdal O., Svendsen J.S., Gutteberg T.J. 1998. Lactoferricin of bovine origin is more active than lactoferricins of human, murine and caprine origin. Scandinavian Journal of Infectious Diseases, 30(5): 513-517.
25. Conneely O.M. 2001. Anti-inflammatory activities of lactoferrin. Journal of the American College of Nutrition, 20 (Suppl 5): 389S-395S.
26. Legrand D., Elass E., Carpentier M., Mazurier J. 2006. Interactions of lactoferrin with cells involved in immune function. Biochemistry and Cell Biology, 84(3):282-290.
27. Tsuda H., Sekine K., Fujita K., Iigo M. 2002. Cancer prevention by bovine lactoferrin and underlying mechanisms, a review of experimental and clinical studies. Biochemistry and Cell Biology, 80(1): 131-136.
28. Roberts A.K., Chierici R., Sawatzki G., Hill M.J., Volpato S., Vigi V. 1992. Supplementation of an adapted formula with bovine lactoferrin: 1. Effect on the infant faecal flora. Acta Paediatrica, 81(2): 119-124.
29. Chierici R., Sawatzki G., Tamisari L., Volpato S., Vigi V. 1992. Supplementation of an adapted formula with bovine lactoferrin. 2. Effects on serum iron, ferritin and zinc levels. Acta Paediatrica, 81(6-7): 475-479.
30. Schulz-Lell G., Dorner K., Oldigs H.D., Sievers E., Schaub J. 1991. Iron availability from an infant formula supplemented with bovine lactoferrin. Acta Paediatrica Scandinavica, 80(2):155-158.
31. Hernell O., Lönnerdal B. 2002. Iron status of infants fed low iron formula: no effect of added bovine lactoferrin or nucleotides. The American Journal of Clinical Nutrition, 76(4):858-864.
32. Davidsson L., Kastenmayer P., Yuen M., Lönnerdal B., Hurrel R.F. 1994. Influence of lactoferrin on iron absorption from human milk in infants. Pediatric Research, 35(1):117-124.
33. Brock J.H. 2002. The physiology of lactoferrin. Biochemistry and Cell Biology, 80(1):1-6.
34. Bethell D.R., Huang J. 2004. Recombinant human lactoferrin treatment for global health issues: iron deficiency and acute diarrhea. Biometals, 17(3):337-342.
35. Tomita M., Wakabayashi H., Yamauchi K., Teraguchi S., Hayasawa H. 2002. Bovine lactoferrin and lactoferricin derived from milk: production and applications. Biochemistry and Cell Biology, 80(1):109-112.
36. Kuwata H., Yip T.T., Tomita M., Hutchens T.W. 1998. Direct evidence of the generación in human stomach of an antimicrobial peptide domain (lactoferricin) from ingested lactoferrin. Biochimica et Biophysica Acta, 1429(1):129-141.
37. Smithers G.W., Ballard F.J., Copeland A.D., De Silva K.J., Dionysius D.A., Francis G.L., Goddard C., Grieve P.A., McInthosh G.H., Mitchell I.R., Pearce R.J., Regester G.O. 1996. New opportunities from the isolation and utilization of whey proteins. Journal of Diary Science, 79(8):1454-1459.
38. Marshall K. 2004. Therapeutic applications of whey protein. Alternative Medicine Review, 9(2): 136-156.
39. Taylor S.L. Determine the potential allergenicity of bovine milk derived lactoferrin. 2004. Abstract 91-5. International Food Technologist Annual Meeting, Jul 12-16, Las Vegas Nevada.
40. Fisher R., Stoger E., Schillberg S., Christou P., Twyman R.M. 2004. Plant based production of biopharmaceuticals. Current Opinion in Plant Biology, 7(2):152-158.
41. Nandi S., Yalda D., Lu S., Nikolov Z., Misaki R., Fujiyama K., Huang N. 2005. Process development and economic evaluation of recombinant human lactoferrin expressed in rice grain. Transgenic Research, 14(3):237-249.
42. Freese B., Hansen M., Gurian-Sherman D. 2004. Potential risks to consumers, the environment, and the California rice industry. Pharmaceutical Rice in California. Rice Report. Fuente: www.centerforfoodsafety.org/pubs/ CARiceReport7.
43. Stowell K.M., Rado T.A., Funk W.D., Tweedie J.W. 1991. Expression of cloned human lactoferrin in baby hamster kidney cells. The Biochemical Journal, 276 (Pt 2): 349-355.
44. Elbehri A. 2005. Biopharming and the food system: examining the potential benefits and risks. Agbioforum, 8(1):18-25.
45. Dyck M.K., Lacroix D., Pothier F., Sirard M.A. 2003. Making recombinant proteins in animals, different systems, different applications. Trends in Biotechnology, 21(9):394-399.
46. van Berkel P.H., Welling M.M., Geerts M., van Veen H.A., Ravensbergen B., Salaheddine M., Pauwels E.K., Pieper F., Nuijens J.H., Nibbering P.H. 2002. Large scale production of recombinant human lactoferrin in the milk of transgenic cows. Nature Biotechnology, 20(5): 484-487.
47. Liu T., Zhang Y.Z., Wu X.F. 2005. High level expression of functionally active human lactoferrin in silkworn larvae. Journal of Biotechnology, 118(3): 246-256.
48. Ward P.P., Piddington C.S., Cunningham G.A., Zhou X., Wyatt R.D., Conneely O.M. 1995. A system for production of commercial quantities of human lactoferrin: a broad spectrum natural antibiotic. Biotechnology, 13(5): 498-503.
49. Lönnerdal B. 2002. Expression of human milk proteins in plants. Journal of the American College of Nutrition, 21(Suppl 3): 218S-221S.
50. Kwon S.Y., Jo S.H., Lee O.S., Choi S.M., Kwak S.S., Lee H.S. 2003. Transgenic ginseng cell lines that produce high levels of a human lactoferrin. Planta Medica, 69(11):1005-1008.
51. Choi S.M., Lee O.S., Kwon S.Y., Kwak S.S., Yu D.Y., Lee H.S. 2003. High expression of a human lactoferrin in transgenic tobacco cell cultures. Biotechnology Letters, 25 (3):213-218.
52. Kruger C.L.Establishing the GRAS status of bovine milk derived lactoferrin. 2004. Abstract 91-3, International Food Technologist Annual Meeting, Jul 12-16, Las Vegas Nevada.
53. Jovaní M., Barberá R., Farré R. 2001. Lactoferrin and its possible role in enrichment of infant formulas. Food Science and Technology International, 7(2):97-103.
54. Ishikado A., Imanaka H., Takeuchi T., Harada E., Makino T. 2005. Liposomalization of lactoferrin enhanced it's anti inflammatory effects via oral administration. Biological and Pharmaceutical Bulletin, 28(9): 1717-1721.
55. DiMario F., Cavallaro L.G., Scarpignato C. 2006. "Rescue" therapies for management of Helicobacter pylori infection. Digestive Diseases, 24(1-2):113-130.
56. Fujihara T., Nagano T., Endo K., Nakamura M., Nakata K. 2000. Lactoferrin protects against UV-B irradiation induced corneal epithelial damage in rats. Cornea, 19(2): 207-211.
57. Fujihara T., Nagano T., Nakamura M., Shirasawa.E. 1998. Lactoferrin suppresses loss of corneal epithelial integrity in a rabbit short-term dry eye model. Journal of Ocular Pharmacology and Therapeutics, 14(2):99-107.
58. Pizzo G., Guiglia R., La Cara M., Giuliana G., D'Angelo M. 2004. The effects of an amine fluoride/stannous fluoride and an antimicrobial host protein mouth rinse on supragingival plaque regrowth. Journal of Periodontology, 75(6):852-857.
59. Kirstila V, Lenander-Lumikari M., Soderling E., Tenovuo J. 1996. Effects of oral hygiene products containing lactoperoxidase, lysozyme, and lactoferrin on the composition of whole saliva and on subjective oral symptoms in patients with xerostomia. Acta Odontologica Scandinavica, 54(6): 391-397.
60. Williams T.J. Willcox M.D., Schneider R.P. 1998. Interactions of bacteria with contact lenses: the effect of soluble protein and carbohydrate on bacterial adhesion to contact lenses. Optometry and Vision Science, 75(4): 266-271.