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Volumn 112, Issue 24, 2005, Pages 3777-3785

Nuclear factor-κB-mediated cell survival involves transcriptional silencing of the mitochondrial death gene BNIP3 in ventricular myocytes

Author keywords

Apoptosis; Cells; Heart failure; Hypoxia; Myocardial infarction

Indexed keywords

I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BNIP3; SYNAPTOTAGMIN; BNIP3 PROTEIN, RAT; CARRIER PROTEIN; I KAPPA B KINASE; ION CHANNEL; MEMBRANE PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; ONCOPROTEIN;

EID: 33644874937     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.105.573899     Document Type: Article
Times cited : (95)

References (39)
  • 1
    • 8844235617 scopus 로고    scopus 로고
    • The mitochondrial death pathway and cardiac myocyte apoptosis
    • Crow MT, Mani K, Nam YJ, Kitsis RN. The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res. 2004;95:957-970.
    • (2004) Circ Res , vol.95 , pp. 957-970
    • Crow, M.T.1    Mani, K.2    Nam, Y.J.3    Kitsis, R.N.4
  • 3
    • 0037047647 scopus 로고    scopus 로고
    • Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes
    • Regula KM, Ens K, Kirshenbaum LA. Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes. Circ Res. 2002;91:226-231.
    • (2002) Circ Res , vol.91 , pp. 226-231
    • Regula, K.M.1    Ens, K.2    Kirshenbaum, L.A.3
  • 4
    • 0036789917 scopus 로고    scopus 로고
    • Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3
    • 3a. Kubasiak LA, Hernandez OM, Bishopric NH, Webster KA. Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3. Proc Natl Acad Sci U S A. 2002;99:12825-12830.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12825-12830
    • Kubasiak, L.A.1    Hernandez, O.M.2    Bishopric, N.H.3    Webster, K.A.4
  • 5
    • 0035901575 scopus 로고    scopus 로고
    • Serpin protein CrmA suppresses hypoxia-mediated apoptosis of ventricular myocytes
    • Gurevich RM, Regula KM, Kirshenbaum LA. Serpin protein CrmA suppresses hypoxia-mediated apoptosis of ventricular myocytes. Circulation. 2001;103:1984-1991.
    • (2001) Circulation , vol.103 , pp. 1984-1991
    • Gurevich, R.M.1    Regula, K.M.2    Kirshenbaum, L.A.3
  • 6
    • 0034731365 scopus 로고    scopus 로고
    • Dynamic shuttling of nuclear factor kappa B between the nucleus and cytoplasm as a consequence of inhibitor dissociation
    • Carlotti F, Dower SK, Qwarnstrom EE. Dynamic shuttling of nuclear factor kappa B between the nucleus and cytoplasm as a consequence of inhibitor dissociation. J Biol Chem. 2000;275:41028-41034.
    • (2000) J Biol Chem , vol.275 , pp. 41028-41034
    • Carlotti, F.1    Dower, S.K.2    Qwarnstrom, E.E.3
  • 7
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 1998;281:1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 8
    • 0034802887 scopus 로고    scopus 로고
    • The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
    • Ashburner BP, Westerheide SD, Baldwin AS Jr. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol. 2001;21:7065-7077.
    • (2001) Mol Cell Biol , vol.21 , pp. 7065-7077
    • Ashburner, B.P.1    Westerheide, S.D.2    Baldwin Jr., A.S.3
  • 9
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol. 2001;21:1249-1259.
    • (2001) Mol Cell Biol , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 10
    • 11144291395 scopus 로고    scopus 로고
    • Nuclear factor-kappaB represses hypoxia-induced mitochondrial defects and cell death of ventricular myocytes
    • Regula KM, Baetz D, Kirshenbaum LA. Nuclear factor-kappaB represses hypoxia-induced mitochondrial defects and cell death of ventricular myocytes. Circulation. 2004;110:3795-3802.
    • (2004) Circulation , vol.110 , pp. 3795-3802
    • Regula, K.M.1    Baetz, D.2    Kirshenbaum, L.A.3
  • 11
    • 0028941640 scopus 로고
    • Adenovirus E1A represses cardiac gene transcription and reactivates DNA synthesis in ventricular myocytes, via alternative pocket protein- And p300-binding domains
    • Kirshenbaum LA, Schneider MD. Adenovirus E1A represses cardiac gene transcription and reactivates DNA synthesis in ventricular myocytes, via alternative pocket protein- and p300-binding domains. J Biol Chem. 1995;270:7791-7794.
    • (1995) J Biol Chem , vol.270 , pp. 7791-7794
    • Kirshenbaum, L.A.1    Schneider, M.D.2
  • 13
    • 0032508486 scopus 로고    scopus 로고
    • Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha
    • de Moissac D, Mustapha S, Greenberg AH, Kirshenbaum LA. Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha. J Biol Chem. 1998;273:23946-23951.
    • (1998) J Biol Chem , vol.273 , pp. 23946-23951
    • De Moissac, D.1    Mustapha, S.2    Greenberg, A.H.3    Kirshenbaum, L.A.4
  • 14
    • 0142105387 scopus 로고    scopus 로고
    • Genetic analysis of NFkappaB/Rel transcription factors defines functional specificities
    • Hoffmann A, Leung TH, Baltimore D. Genetic analysis of NFkappaB/Rel transcription factors defines functional specificities. EMBO J. 2003;22:5530-5539.
    • (2003) EMBO J , vol.22 , pp. 5530-5539
    • Hoffmann, A.1    Leung, T.H.2    Baltimore, D.3
  • 15
    • 0035379555 scopus 로고    scopus 로고
    • Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38
    • Madrid LV, Mayo MW, Reuther JY, Baldwin AS Jr. Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38. J Biol Chem. 2001;276:18934-18940.
    • (2001) J Biol Chem , vol.276 , pp. 18934-18940
    • Madrid, L.V.1    Mayo, M.W.2    Reuther, J.Y.3    Baldwin Jr., A.S.4
  • 17
    • 0033621618 scopus 로고    scopus 로고
    • Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions
    • O'Mahony A, Lin X, Geleziunas R, Greene WC. Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions. Mol Cell Biol. 2000;20:1170-1178.
    • (2000) Mol Cell Biol , vol.20 , pp. 1170-1178
    • O'Mahony, A.1    Lin, X.2    Geleziunas, R.3    Greene, W.C.4
  • 18
    • 0037064129 scopus 로고    scopus 로고
    • IKK beta is required for Bcl-2-mediated NF-kappa B activation in ventricular myocytes
    • Regula KM, Ens K, Kirshenbaum LA. IKK beta is required for Bcl-2-mediated NF-kappa B activation in ventricular myocytes. J Biol Chem. 2002;277:38676-38682.
    • (2002) J Biol Chem , vol.277 , pp. 38676-38682
    • Regula, K.M.1    Ens, K.2    Kirshenbaum, L.A.3
  • 19
    • 0037047647 scopus 로고    scopus 로고
    • Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes
    • Regula KM, Ens K, Kirshenbaum LA. Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes. Circ Res. 2002;91:226-231.
    • (2002) Circ Res , vol.91 , pp. 226-231
    • Regula, K.M.1    Ens, K.2    Kirshenbaum, L.A.3
  • 21
    • 0033959317 scopus 로고    scopus 로고
    • Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes
    • Moissac D, Gurevich RM, Zheng H, Singal PK, Kirshenbaum LA. Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes. J Mol Cell Cardiol. 2000;32:53-63.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 53-63
    • Moissac, D.1    Gurevich, R.M.2    Zheng, H.3    Singal, P.K.4    Kirshenbaum, L.A.5
  • 23
    • 0034913650 scopus 로고    scopus 로고
    • p53 activates the mitochondrial death pathway and apoptosis of ventricular myocytes independent of de novo gene transcription
    • Regula KM, Kirshenbaum LA. p53 activates the mitochondrial death pathway and apoptosis of ventricular myocytes independent of de novo gene transcription. J Mol Cell Cardiol. 2000;33:1435-1445.
    • (2000) J Mol Cell Cardiol , vol.33 , pp. 1435-1445
    • Regula, K.M.1    Kirshenbaum, L.A.2
  • 24
    • 0033831027 scopus 로고    scopus 로고
    • A direct requirement of nuclear factor-kappa B for suppression of apoptosis in ventricular myocytes
    • Mustapha S, Kirshner A, de Moissac D, Kirshenbaum LA. A direct requirement of nuclear factor-kappa B for suppression of apoptosis in ventricular myocytes. Am J Physiol. 2000;279:H939-H945.
    • (2000) Am J Physiol , vol.279
    • Mustapha, S.1    Kirshner, A.2    De Moissac, D.3    Kirshenbaum, L.A.4
  • 25
    • 0033532386 scopus 로고    scopus 로고
    • The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
    • Li ZW, Chu W, Hu Y, Delhase M, Deerinck T, Ellisman M, Johnson R, Karin M. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J Exp Med. 1999;189:1839-1845.
    • (1999) J Exp Med , vol.189 , pp. 1839-1845
    • Li, Z.W.1    Chu, W.2    Hu, Y.3    Delhase, M.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 26
    • 0032848297 scopus 로고    scopus 로고
    • Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis
    • de Moissac D, Zheng H, Kirshenbaum LA. Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis. J Biol Chem. 1999;274:29505-29509.
    • (1999) J Biol Chem , vol.274 , pp. 29505-29509
    • De Moissac, D.1    Zheng, H.2    Kirshenbaum, L.A.3
  • 30
    • 0034255036 scopus 로고    scopus 로고
    • Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
    • Bruick RK. Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci U S A. 2000;97:9082-9087.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 9082-9087
    • Bruick, R.K.1
  • 31
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang CY, Mayo MW, Baldwin AS Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science. 1996;274:784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 32
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
    • Beg AA, Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science. 1996;274:782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 33
    • 0023143707 scopus 로고
    • In vitro transcription of immunoglobulin genes in a B-cell extract: Effects of enhancer and promoter sequences
    • Sen R, Baltimore D. In vitro transcription of immunoglobulin genes in a B-cell extract: effects of enhancer and promoter sequences. Mol Cell Biol. 1987;7:1989-1994.
    • (1987) Mol Cell Biol , vol.7 , pp. 1989-1994
    • Sen, R.1    Baltimore, D.2
  • 34
    • 0022644806 scopus 로고
    • A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes
    • Singh H, Sen R, Baltimore D, Sharp PA. A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature. 1986;319:154-158.
    • (1986) Nature , vol.319 , pp. 154-158
    • Singh, H.1    Sen, R.2    Baltimore, D.3    Sharp, P.A.4
  • 36
    • 0027316201 scopus 로고
    • Functional and physical associations between NF-kappa B and C/EBP family members: A Rel domain-bZIP interaction
    • Stein B, Cogswell PC, Baldwin AS Jr. Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction. Mol Cell Biol. 1993;13:3964-3974.
    • (1993) Mol Cell Biol , vol.13 , pp. 3964-3974
    • Stein, B.1    Cogswell, P.C.2    Baldwin Jr., A.S.3
  • 37
    • 0036838539 scopus 로고    scopus 로고
    • NF-kappaB inhibits transcription of the H(+)-K(+)-ATPase alpha(2)-subunit gene: Role of histone deacetylases
    • Zhang W, Kone BC. NF-kappaB inhibits transcription of the H(+)-K(+)-ATPase alpha(2)-subunit gene: role of histone deacetylases. Am J Physiol. 2002;283:F904-F911.
    • (2002) Am J Physiol , vol.283
    • Zhang, W.1    Kone, B.C.2
  • 38
    • 0035912094 scopus 로고    scopus 로고
    • Repression of GADD153/CHOP by NF-kappaB: A possible cellular defense against endoplasmic reticulum stress-induced cell death
    • Nozaki S, Sledge GW Jr, Nakshatri H. Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death. Oncogene. 2001;20:2178-2185.
    • (2001) Oncogene , vol.20 , pp. 2178-2185
    • Nozaki, S.1    Sledge Jr., G.W.2    Nakshatri, H.3
  • 39
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
    • Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature. 1995;376:167-170.
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5


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