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Volumn 53, Issue 5, 2007, Pages 643-656

Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice

Author keywords

5 Hydroxy l tryptophan (5 HTP); Serotonin 1a receptors (5 HT1A, Htr1a); Serotonin 2a receptors (5 HT2A, Htr2a); Serotonin 7 receptors (5 HT7, Htr7); Serotonin syndrome; Serotonin transporter (SERT) knockout mice

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; 5 HYDROXYTRYPTOPHAN; CLORGYLINE; GLEMANSERIN; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE B INHIBITOR; MONOAMINE OXIDASE INHIBITOR; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; RECEPTOR; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN TRANSPORTER; TRANYLCYPROMINE;

EID: 34848871368     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2007.07.009     Document Type: Article
Times cited : (58)

References (59)
  • 1
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice
    • Bengel D., Murphy D.L., Andrews A.M., Wichems C.H., Feltner D., Heils A., Mossner R., Westphal H., and Lesch K.P. Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice. Mol. Pharmacol. 53 (1998) 649-655
    • (1998) Mol. Pharmacol. , vol.53 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3    Wichems, C.H.4    Feltner, D.5    Heils, A.6    Mossner, R.7    Westphal, H.8    Lesch, K.P.9
  • 2
    • 30744436816 scopus 로고    scopus 로고
    • Mice over-expressing the 5-HT(1A) receptor in cortex and dentate gyrus display exaggerated locomotor and hypothermic response to 8-OH-DPAT
    • Bert B., Fink H., Hortnagl H., Veh R.W., Davies B., Theuring F., and Kusserow H. Mice over-expressing the 5-HT(1A) receptor in cortex and dentate gyrus display exaggerated locomotor and hypothermic response to 8-OH-DPAT. Behav. Brain Res. 167 (2006) 328-341
    • (2006) Behav. Brain Res. , vol.167 , pp. 328-341
    • Bert, B.1    Fink, H.2    Hortnagl, H.3    Veh, R.W.4    Davies, B.5    Theuring, F.6    Kusserow, H.7
  • 3
    • 0025815784 scopus 로고
    • Direct evidence for an important species difference in the mechanism of 8-OH-DPAT-induced hypothermia
    • Bill D.J., Knight M., Forster E.A., and Fletcher A. Direct evidence for an important species difference in the mechanism of 8-OH-DPAT-induced hypothermia. Br. J. Pharmacol. 103 (1991) 1857-1864
    • (1991) Br. J. Pharmacol. , vol.103 , pp. 1857-1864
    • Bill, D.J.1    Knight, M.2    Forster, E.A.3    Fletcher, A.4
  • 4
    • 0032134522 scopus 로고    scopus 로고
    • 5-Hydroxytryptophan: a clinically-effective serotonin precursor
    • Birdsall T.C. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern. Med. Rev. 3 (1998) 271-280
    • (1998) Altern. Med. Rev. , vol.3 , pp. 271-280
    • Birdsall, T.C.1
  • 6
    • 34247270861 scopus 로고    scopus 로고
    • Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents
    • Bonaventure P., Kelly L., Aluisio L., Shelton J., Lord B., Galici R., Miller K., Atack J., Lovenberg T.W., and Dugovic C. Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents. J. Pharmacol. Exp. Ther. 321 (2007) 690-698
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 690-698
    • Bonaventure, P.1    Kelly, L.2    Aluisio, L.3    Shelton, J.4    Lord, B.5    Galici, R.6    Miller, K.7    Atack, J.8    Lovenberg, T.W.9    Dugovic, C.10
  • 7
    • 1642463529 scopus 로고    scopus 로고
    • Sex hormone-dependent desensitization of 5-HT1A autoreceptors in knockout mice deficient in the 5-HT transporter
    • Bouali S., Evrard A., Chastanet M., Lesch K.P., Hamon M., and Adrien J. Sex hormone-dependent desensitization of 5-HT1A autoreceptors in knockout mice deficient in the 5-HT transporter. Eur. J. Neurosci. 18 (2003) 2203-2212
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 2203-2212
    • Bouali, S.1    Evrard, A.2    Chastanet, M.3    Lesch, K.P.4    Hamon, M.5    Adrien, J.6
  • 8
    • 15044361698 scopus 로고    scopus 로고
    • The serotonin syndrome
    • Boyer E.W., and Shannon M. The serotonin syndrome. N. Engl. J. Med. 352 (2005) 1112-1120
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1112-1120
    • Boyer, E.W.1    Shannon, M.2
  • 9
    • 0036890097 scopus 로고    scopus 로고
    • Excess mortality in depression: a meta-analysis of community studies
    • Cuijpers P., and Smit F. Excess mortality in depression: a meta-analysis of community studies. J. Affect. Disord. 72 (2002) 227-236
    • (2002) J. Affect. Disord. , vol.72 , pp. 227-236
    • Cuijpers, P.1    Smit, F.2
  • 10
    • 0042377403 scopus 로고    scopus 로고
    • The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity
    • Dunkley E.J., Isbister G.K., Sibbritt D., Dawson A.H., and Whyte I.M. The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity. QJM 96 (2003) 635-642
    • (2003) QJM , vol.96 , pp. 635-642
    • Dunkley, E.J.1    Isbister, G.K.2    Sibbritt, D.3    Dawson, A.H.4    Whyte, I.M.5
  • 12
    • 34848851261 scopus 로고    scopus 로고
    • Mediation of exaggerated serotonin syndrome-like behaviors and temperature responses in serotonin transporter knockout mice by 5-HT1A and 5-HT7 serotonin receptors: a possible model and mechanism for differential human vulnerability to the serotonin syndrome
    • Fox M.A., Jensen C.L., and Murphy D.L. Mediation of exaggerated serotonin syndrome-like behaviors and temperature responses in serotonin transporter knockout mice by 5-HT1A and 5-HT7 serotonin receptors: a possible model and mechanism for differential human vulnerability to the serotonin syndrome. Neuropsychopharmacology 31 (2006) S221-S222
    • (2006) Neuropsychopharmacology , vol.31
    • Fox, M.A.1    Jensen, C.L.2    Murphy, D.L.3
  • 13
    • 34249040351 scopus 로고    scopus 로고
    • Exaggerated serotonin syndrome in serotonin transporter knockout mice
    • Fox M.A., and Murphy D.L. Exaggerated serotonin syndrome in serotonin transporter knockout mice. Int. J. Neuropsychopharmacol. 9 (2006) S174-S175
    • (2006) Int. J. Neuropsychopharmacol. , vol.9
    • Fox, M.A.1    Murphy, D.L.2
  • 14
    • 33744904175 scopus 로고    scopus 로고
    • A review of serotonin toxicity data: implications for the mechanisms of antidepressant drug action
    • Gillman P.K. A review of serotonin toxicity data: implications for the mechanisms of antidepressant drug action. Biol. Psychiatry. 59 (2006) 1046-1051
    • (2006) Biol. Psychiatry. , vol.59 , pp. 1046-1051
    • Gillman, P.K.1
  • 15
    • 0035122950 scopus 로고    scopus 로고
    • Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study
    • Gobbi G., Murphy D.L., Lesch K., and Blier P. Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. J. Pharmacol. Exp. Ther. 296 (2001) 987-995
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 987-995
    • Gobbi, G.1    Murphy, D.L.2    Lesch, K.3    Blier, P.4
  • 16
    • 0022346496 scopus 로고
    • The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). A model of presynaptic 5-HT1 function
    • Goodwin G.M., De Souza R.J., and Green A.R. The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). A model of presynaptic 5-HT1 function. Neuropharmacology 24 (1985) 1187-1194
    • (1985) Neuropharmacology , vol.24 , pp. 1187-1194
    • Goodwin, G.M.1    De Souza, R.J.2    Green, A.R.3
  • 17
    • 0023109436 scopus 로고
    • Attenuation by electroconvulsive shock and antidepressant drugs of the 5-HT1A receptor-mediated hypothermia and serotonin syndrome produced by 8-OH-DPAT in the rat
    • Goodwin G.M., De Souza R.J., and Green A.R. Attenuation by electroconvulsive shock and antidepressant drugs of the 5-HT1A receptor-mediated hypothermia and serotonin syndrome produced by 8-OH-DPAT in the rat. Psychopharmacology (Berlin) 91 (1987) 500-505
    • (1987) Psychopharmacology (Berlin) , vol.91 , pp. 500-505
    • Goodwin, G.M.1    De Souza, R.J.2    Green, A.R.3
  • 18
    • 0023117333 scopus 로고
    • The pharmacology of the behavioural and hypothermic responses of rats to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)
    • Goodwin G.M., De Souza R.J., Green A.R., and Heal D.J. The pharmacology of the behavioural and hypothermic responses of rats to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Psychopharmacology (Berlin) 91 (1987) 506-511
    • (1987) Psychopharmacology (Berlin) , vol.91 , pp. 506-511
    • Goodwin, G.M.1    De Souza, R.J.2    Green, A.R.3    Heal, D.J.4
  • 19
    • 0022991462 scopus 로고
    • The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism
    • Goodwin G.M., De Souza R.J., Wood A.J., and Green A.R. The enhancement by lithium of the 5-HT1A mediated serotonin syndrome produced by 8-OH-DPAT in the rat: evidence for a post-synaptic mechanism. Psychopharmacology (Berlin) 90 (1986) 488-493
    • (1986) Psychopharmacology (Berlin) , vol.90 , pp. 488-493
    • Goodwin, G.M.1    De Souza, R.J.2    Wood, A.J.3    Green, A.R.4
  • 21
    • 27944496843 scopus 로고    scopus 로고
    • 5-HT7 receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern
    • Hedlund P.B., Huitron-Resendiz S., Henriksen S.J., and Sutcliffe J.G. 5-HT7 receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern. Biol. Psychiatry 58 (2005) 831-837
    • (2005) Biol. Psychiatry , vol.58 , pp. 831-837
    • Hedlund, P.B.1    Huitron-Resendiz, S.2    Henriksen, S.J.3    Sutcliffe, J.G.4
  • 22
    • 0345305849 scopus 로고    scopus 로고
    • Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background
    • Holmes A., Li Q., Murphy D.L., Gold E., and Crawley J.N. Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background. Genes Brain Behav. 2 (2003) 365-380
    • (2003) Genes Brain Behav. , vol.2 , pp. 365-380
    • Holmes, A.1    Li, Q.2    Murphy, D.L.3    Gold, E.4    Crawley, J.N.5
  • 26
    • 27644562392 scopus 로고    scopus 로고
    • The pathophysiology of serotonin toxicity in animals and humans: implications for diagnosis and treatment
    • Isbister G.K., and Buckley N.A. The pathophysiology of serotonin toxicity in animals and humans: implications for diagnosis and treatment. Clin. Neuropharmacol. 28 (2005) 205-214
    • (2005) Clin. Neuropharmacol. , vol.28 , pp. 205-214
    • Isbister, G.K.1    Buckley, N.A.2
  • 27
    • 33644526575 scopus 로고    scopus 로고
    • Effects of co-administration of a selective serotonin reuptake inhibitor and monoamine oxidase inhibitors on 5-HT-related behavior in rats
    • Izumi T., Iwamoto N., Kitaichi Y., Kato A., Inoue T., and Koyama T. Effects of co-administration of a selective serotonin reuptake inhibitor and monoamine oxidase inhibitors on 5-HT-related behavior in rats. Eur. J. Pharmacol. 532 (2006) 258-264
    • (2006) Eur. J. Pharmacol. , vol.532 , pp. 258-264
    • Izumi, T.1    Iwamoto, N.2    Kitaichi, Y.3    Kato, A.4    Inoue, T.5    Koyama, T.6
  • 28
    • 0017086367 scopus 로고
    • An animal behavior model for studying central serotonergic synapses
    • Jacobs B.L. An animal behavior model for studying central serotonergic synapses. Life Sci. 19 (1976) 777-785
    • (1976) Life Sci. , vol.19 , pp. 777-785
    • Jacobs, B.L.1
  • 29
    • 34249065202 scopus 로고    scopus 로고
    • Hypolocomotion, anxiety and serotonin syndrome-like behavior contribute to the complex phenotype of serotonin transporter knockout mice
    • Kalueff A.V., Fox M.A., Gallagher P.S., and Murphy D.L. Hypolocomotion, anxiety and serotonin syndrome-like behavior contribute to the complex phenotype of serotonin transporter knockout mice. Genes Brain Behav. 6 (2007) 389-400
    • (2007) Genes Brain Behav. , vol.6 , pp. 389-400
    • Kalueff, A.V.1    Fox, M.A.2    Gallagher, P.S.3    Murphy, D.L.4
  • 30
    • 0022359434 scopus 로고
    • Central serotonergic responses and behavioural adaptation to repeated immobilisation: the effect of the corticosterone synthesis inhibitor metyrapone
    • Kennett G.A., Dickinson S.L., and Curzon G. Central serotonergic responses and behavioural adaptation to repeated immobilisation: the effect of the corticosterone synthesis inhibitor metyrapone. Eur. J. Pharmacol. 119 (1985) 143-152
    • (1985) Eur. J. Pharmacol. , vol.119 , pp. 143-152
    • Kennett, G.A.1    Dickinson, S.L.2    Curzon, G.3
  • 32
    • 33746191363 scopus 로고    scopus 로고
    • Contribution of spinal 5-HT1A and 5-HT7 receptors to locomotor-like movement induced by 8-OH-DPAT in spinal cord-transected mice
    • Landry E.S., Lapointe N.P., Rouillard C., Levesque D., Hedlund P.B., and Guertin P.A. Contribution of spinal 5-HT1A and 5-HT7 receptors to locomotor-like movement induced by 8-OH-DPAT in spinal cord-transected mice. Eur. J. Neurosci. 24 (2006) 535-546
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 535-546
    • Landry, E.S.1    Lapointe, N.P.2    Rouillard, C.3    Levesque, D.4    Hedlund, P.B.5    Guertin, P.A.6
  • 34
    • 0034331195 scopus 로고    scopus 로고
    • Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences
    • Li Q., Wichems C., Heils A., Lesch K.P., and Murphy D.L. Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences. J. Neurosci. 20 (2000) 7888-7895
    • (2000) J. Neurosci. , vol.20 , pp. 7888-7895
    • Li, Q.1    Wichems, C.2    Heils, A.3    Lesch, K.P.4    Murphy, D.L.5
  • 35
    • 0032706095 scopus 로고    scopus 로고
    • Reduction of 5-hydroxytryptamine (5-HT) (1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice
    • Li Q., Wichems C., Heils A., Van De Kar L.D., Lesch K.P., and Murphy D.L. Reduction of 5-hydroxytryptamine (5-HT) (1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice. J. Pharmacol. Exp. Ther. 291 (1999) 999-1007
    • (1999) J. Pharmacol. Exp. Ther. , vol.291 , pp. 999-1007
    • Li, Q.1    Wichems, C.2    Heils, A.3    Van De Kar, L.D.4    Lesch, K.P.5    Murphy, D.L.6
  • 36
    • 0037343950 scopus 로고    scopus 로고
    • Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice
    • Li Q., Wichems C.H., Ma L., Van de Kar L.D., Garcia F., and Murphy D.L. Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice. J. Neurochem. 84 (2003) 1256-1265
    • (2003) J. Neurochem. , vol.84 , pp. 1256-1265
    • Li, Q.1    Wichems, C.H.2    Ma, L.3    Van de Kar, L.D.4    Garcia, F.5    Murphy, D.L.6
  • 37
    • 0021336087 scopus 로고
    • Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the rat
    • Lucki I., Nobler M.S., and Frazer A. Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the rat. J. Pharmacol. Exp. Ther. 228 (1984) 133-139
    • (1984) J. Pharmacol. Exp. Ther. , vol.228 , pp. 133-139
    • Lucki, I.1    Nobler, M.S.2    Frazer, A.3
  • 38
    • 0035869610 scopus 로고    scopus 로고
    • Functional consequences of 5-HT transporter gene disruption on 5-HT(1a) receptor-mediated regulation of dorsal raphe and hippocampal cell activity
    • Mannoury la Cour C., Boni C., Hanoun N., Lesch K.P., Hamon M., and Lanfumey L. Functional consequences of 5-HT transporter gene disruption on 5-HT(1a) receptor-mediated regulation of dorsal raphe and hippocampal cell activity. J. Neurosci. 21 (2001) 2178-2185
    • (2001) J. Neurosci. , vol.21 , pp. 2178-2185
    • Mannoury la Cour, C.1    Boni, C.2    Hanoun, N.3    Lesch, K.P.4    Hamon, M.5    Lanfumey, L.6
  • 39
    • 0026784676 scopus 로고
    • Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants
    • Martin K.F., Phillips I., Hearson M., Prow M.R., and Heal D.J. Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants. Br. J. Pharmacol. 107 (1992) 15-21
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 15-21
    • Martin, K.F.1    Phillips, I.2    Hearson, M.3    Prow, M.R.4    Heal, D.J.5
  • 40
    • 10344221595 scopus 로고    scopus 로고
    • Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression
    • Mathews T.A., Fedele D.E., Coppelli F.M., Avila A.M., Murphy D.L., and Andrews A.M. Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. J. Neurosci. Methods 140 (2004) 169-181
    • (2004) J. Neurosci. Methods , vol.140 , pp. 169-181
    • Mathews, T.A.1    Fedele, D.E.2    Coppelli, F.M.3    Avila, A.M.4    Murphy, D.L.5    Andrews, A.M.6
  • 41
    • 17144466384 scopus 로고    scopus 로고
    • Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice
    • Montanez S., Owens W.A., Gould G.G., Murphy D.L., and Daws L.C. Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice. J. Neurochem. 86 (2003) 210-219
    • (2003) J. Neurochem. , vol.86 , pp. 210-219
    • Montanez, S.1    Owens, W.A.2    Gould, G.G.3    Murphy, D.L.4    Daws, L.C.5
  • 42
    • 0034119790 scopus 로고    scopus 로고
    • Risperidone counteracts lethality in an animal model of the serotonin syndrome
    • Nisijima K., Yoshino T., and Ishiguro T. Risperidone counteracts lethality in an animal model of the serotonin syndrome. Psychopharmacology (Berlin) 150 (2000) 9-14
    • (2000) Psychopharmacology (Berlin) , vol.150 , pp. 9-14
    • Nisijima, K.1    Yoshino, T.2    Ishiguro, T.3
  • 43
    • 0035951658 scopus 로고    scopus 로고
    • Potent serotonin (5-HT) (2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome
    • Nisijima K., Yoshino T., Yui K., and Katoh S. Potent serotonin (5-HT) (2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome. Brain Res. 890 (2001) 23-31
    • (2001) Brain Res. , vol.890 , pp. 23-31
    • Nisijima, K.1    Yoshino, T.2    Yui, K.3    Katoh, S.4
  • 44
    • 0035977577 scopus 로고    scopus 로고
    • Plasticity in serotonin uptake in primary neuronal cultures of serotonin transporter knockout mice
    • Pan Y., Gembom E., Peng W., Lesch K.P., Mossner R., and Simantov R. Plasticity in serotonin uptake in primary neuronal cultures of serotonin transporter knockout mice. Brain Res. Dev. Brain Res. 126 (2001) 125-129
    • (2001) Brain Res. Dev. Brain Res. , vol.126 , pp. 125-129
    • Pan, Y.1    Gembom, E.2    Peng, W.3    Lesch, K.P.4    Mossner, R.5    Simantov, R.6
  • 45
    • 13244289981 scopus 로고    scopus 로고
    • Chronoamperometry to determine differential reductions in uptake in brain synaptosomes from serotonin transporter knockout mice
    • Perez X.A., and Andrews A.M. Chronoamperometry to determine differential reductions in uptake in brain synaptosomes from serotonin transporter knockout mice. Anal. Chem. 77 (2005) 818-826
    • (2005) Anal. Chem. , vol.77 , pp. 818-826
    • Perez, X.A.1    Andrews, A.M.2
  • 47
    • 21244500509 scopus 로고    scopus 로고
    • 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter
    • Qu Y., Villacreses N., Murphy D.L., and Rapoport S.I. 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter. Psychopharmacology (Berlin) 180 (2005) 12-20
    • (2005) Psychopharmacology (Berlin) , vol.180 , pp. 12-20
    • Qu, Y.1    Villacreses, N.2    Murphy, D.L.3    Rapoport, S.I.4
  • 48
    • 0035059877 scopus 로고    scopus 로고
    • Abnormal trafficking and subcellular localization of an N-terminally truncated serotonin transporter protein
    • Ravary A., Muzerelle A., Darmon M., Murphy D.L., Moessner R., Lesch K.P., and Gaspar P. Abnormal trafficking and subcellular localization of an N-terminally truncated serotonin transporter protein. Eur. J. Neurosci. 13 (2001) 1349-1362
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 1349-1362
    • Ravary, A.1    Muzerelle, A.2    Darmon, M.3    Murphy, D.L.4    Moessner, R.5    Lesch, K.P.6    Gaspar, P.7
  • 50
    • 3342965212 scopus 로고    scopus 로고
    • Extracellular serotonin, dopamine and glutamate levels are elevated in the hypothalamus in a serotonin syndrome animal model induced by tranylcypromine and fluoxetine
    • Shioda K., Nisijima K., Yoshino T., and Kato S. Extracellular serotonin, dopamine and glutamate levels are elevated in the hypothalamus in a serotonin syndrome animal model induced by tranylcypromine and fluoxetine. Prog. Neuropsychopharmacol. Biol. Psychiatry. 28 (2004) 633-640
    • (2004) Prog. Neuropsychopharmacol. Biol. Psychiatry. , vol.28 , pp. 633-640
    • Shioda, K.1    Nisijima, K.2    Yoshino, T.3    Kato, S.4
  • 51
    • 0022457933 scopus 로고
    • Differential effects of 5-hydroxytryptamine1a selective drugs on the 5-HT behavioral syndrome
    • Smith L.M., and Peroutka S.J. Differential effects of 5-hydroxytryptamine1a selective drugs on the 5-HT behavioral syndrome. Pharmacol. Biochem. Behav. 24 (1986) 1513-1519
    • (1986) Pharmacol. Biochem. Behav. , vol.24 , pp. 1513-1519
    • Smith, L.M.1    Peroutka, S.J.2
  • 52
    • 0025869797 scopus 로고
    • The serotonin syndrome
    • Sternbach H. The serotonin syndrome. Am. J. Psychiatry. 148 (1991) 705-713
    • (1991) Am. J. Psychiatry. , vol.148 , pp. 705-713
    • Sternbach, H.1
  • 56
    • 33751175401 scopus 로고    scopus 로고
    • Potential anxiolytic and antidepressant effects of the selective 5-HT7 receptor antagonist SB 269970 after intrahippocampal administration to rats
    • Wesolowska A., Nikiforuk A., and Stachowicz K. Potential anxiolytic and antidepressant effects of the selective 5-HT7 receptor antagonist SB 269970 after intrahippocampal administration to rats. Eur. J. Pharmacol. 553 (2006) 185-190
    • (2006) Eur. J. Pharmacol. , vol.553 , pp. 185-190
    • Wesolowska, A.1    Nikiforuk, A.2    Stachowicz, K.3
  • 57
    • 33747075753 scopus 로고    scopus 로고
    • Effect of the selective 5-HT7 receptor antagonist SB 269970 in animal models of anxiety and depression
    • Wesolowska A., Nikiforuk A., Stachowicz K., and Tatarczynska E. Effect of the selective 5-HT7 receptor antagonist SB 269970 in animal models of anxiety and depression. Neuropharmacology 51 (2006) 578-586
    • (2006) Neuropharmacology , vol.51 , pp. 578-586
    • Wesolowska, A.1    Nikiforuk, A.2    Stachowicz, K.3    Tatarczynska, E.4
  • 58
    • 33845741592 scopus 로고    scopus 로고
    • Enhancement of the anti-immobility action of antidepressants by a selective 5-HT(7) receptor antagonist in the forced swimming test in mice
    • Wesolowska A., Tatarczynska E., Nikiforuk A., and Chojnacka-Wojcik E. Enhancement of the anti-immobility action of antidepressants by a selective 5-HT(7) receptor antagonist in the forced swimming test in mice. Eur. J. Pharmacol. 555 (2007) 43-47
    • (2007) Eur. J. Pharmacol. , vol.555 , pp. 43-47
    • Wesolowska, A.1    Tatarczynska, E.2    Nikiforuk, A.3    Chojnacka-Wojcik, E.4
  • 59
    • 0023788434 scopus 로고
    • The behavioural effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in mice
    • Yamada J., Sugimoto Y., and Horisaka K. The behavioural effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in mice. Eur. J. Pharmacol. 154 (1988) 299-304
    • (1988) Eur. J. Pharmacol. , vol.154 , pp. 299-304
    • Yamada, J.1    Sugimoto, Y.2    Horisaka, K.3


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