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Volumn 27, Issue 6, 2007, Pages 992-1004

The MUC1 and Galectin-3 Oncoproteins Function in a MicroRNA-Dependent Regulatory Loop

Author keywords

CELLCYLCE; RNA

Indexed keywords

ASPARAGINE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GALECTIN 3; MESSENGER RNA; MICRORNA; MUCIN 1; ONCOPROTEIN;

EID: 34748902247     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2007.07.031     Document Type: Article
Times cited : (162)

References (53)
  • 1
    • 1642483757 scopus 로고    scopus 로고
    • Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes
    • Ahmad N., Gabius H.J., Andre S., Kaltner H., Sabesan S., Roy R., Liu B., Macaluso F., and Brewer C.F. Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes. J. Biol. Chem. 279 (2004) 10841-10847
    • (2004) J. Biol. Chem. , vol.279 , pp. 10841-10847
    • Ahmad, N.1    Gabius, H.J.2    Andre, S.3    Kaltner, H.4    Sabesan, S.5    Roy, R.6    Liu, B.7    Macaluso, F.8    Brewer, C.F.9
  • 2
    • 0030707480 scopus 로고    scopus 로고
    • Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family
    • Akahani S., Nangia-Makker P., Inohara H., Kim H.R., and Raz A. Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res. 57 (1997) 5272-5276
    • (1997) Cancer Res. , vol.57 , pp. 5272-5276
    • Akahani, S.1    Nangia-Makker, P.2    Inohara, H.3    Kim, H.R.4    Raz, A.5
  • 4
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2004) 281-297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 6
    • 0035825644 scopus 로고    scopus 로고
    • Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation
    • Demetriou M., Granovsky M., Quaggin S., and Dennis J.W. Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation. Nature 409 (2001) 733-739
    • (2001) Nature , vol.409 , pp. 733-739
    • Demetriou, M.1    Granovsky, M.2    Quaggin, S.3    Dennis, J.W.4
  • 8
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • Esquela-Kerscher A., and Slack F.J. Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer 6 (2006) 259-269
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 9
    • 28544448610 scopus 로고    scopus 로고
    • MUC1 oncoprotein blocks GSK3β-mediated phosphorylation and degradation of β-catenin
    • Huang L., Chen D., Liu D., Yin L., Kharbanda S., and Kufe D. MUC1 oncoprotein blocks GSK3β-mediated phosphorylation and degradation of β-catenin. Cancer Res. 65 (2005) 10413-10422
    • (2005) Cancer Res. , vol.65 , pp. 10413-10422
    • Huang, L.1    Chen, D.2    Liu, D.3    Yin, L.4    Kharbanda, S.5    Kufe, D.6
  • 11
  • 12
    • 0031819671 scopus 로고    scopus 로고
    • The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter
    • Kadrofske M.M., Openo K.P., and Wang J.L. The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter. Arch. Biochem. Biophys. 349 (1998) 7-20
    • (1998) Arch. Biochem. Biophys. , vol.349 , pp. 7-20
    • Kadrofske, M.M.1    Openo, K.P.2    Wang, J.L.3
  • 13
    • 6044244941 scopus 로고    scopus 로고
    • Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells
    • Kasashima K., Nakamura Y., and Kozu T. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. Biochem. Biophys. Res. Commun. 322 (2004) 403-410
    • (2004) Biochem. Biophys. Res. Commun. , vol.322 , pp. 403-410
    • Kasashima, K.1    Nakamura, Y.2    Kozu, T.3
  • 15
    • 0021740104 scopus 로고
    • Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
    • Kufe D., Inghirami G., Abe M., Hayes D., Justi-Wheeler H., and Schlom J. Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma 3 (1984) 223-232
    • (1984) Hybridoma , vol.3 , pp. 223-232
    • Kufe, D.1    Inghirami, G.2    Abe, M.3    Hayes, D.4    Justi-Wheeler, H.5    Schlom, J.6
  • 16
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee R.C., and Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 294 (2001) 862-864
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 18
    • 0031723707 scopus 로고    scopus 로고
    • Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin
    • Li Y., Bharti A., Chen D., Gong J., and Kufe D. Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin. Mol. Cell. Biol. 18 (1998) 7216-7224
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7216-7224
    • Li, Y.1    Bharti, A.2    Chen, D.3    Gong, J.4    Kufe, D.5
  • 19
    • 0035794215 scopus 로고    scopus 로고
    • The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin
    • Li Y., Kuwahara H., Ren J., Wen G., and Kufe D. The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin. J. Biol. Chem. 276 (2001) 6061-6064
    • (2001) J. Biol. Chem. , vol.276 , pp. 6061-6064
    • Li, Y.1    Kuwahara, H.2    Ren, J.3    Wen, G.4    Kufe, D.5
  • 20
    • 0035929643 scopus 로고    scopus 로고
    • The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin
    • Li Y., Ren J., Yu W.-H., Li G., Kuwahara H., Yin L., Carraway K.L., and Kufe D. The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin. J. Biol. Chem. 276 (2001) 35239-35242
    • (2001) J. Biol. Chem. , vol.276 , pp. 35239-35242
    • Li, Y.1    Ren, J.2    Yu, W.-H.3    Li, G.4    Kuwahara, H.5    Yin, L.6    Carraway, K.L.7    Kufe, D.8
  • 21
    • 11144240877 scopus 로고    scopus 로고
    • DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7
    • Li Y., Chen W., Ren J., Yu W., Li Q., Yoshida K., and Kufe D. DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7. Cancer Biol. Ther. 2 (2003) 187-193
    • (2003) Cancer Biol. Ther. , vol.2 , pp. 187-193
    • Li, Y.1    Chen, W.2    Ren, J.3    Yu, W.4    Li, Q.5    Yoshida, K.6    Kufe, D.7
  • 22
    • 0041850346 scopus 로고    scopus 로고
    • Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
    • Li Y., Liu D., Chen D., Kharbanda S., and Kufe D. Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 22 (2003) 6107-6110
    • (2003) Oncogene , vol.22 , pp. 6107-6110
    • Li, Y.1    Liu, D.2    Chen, D.3    Kharbanda, S.4    Kufe, D.5
  • 23
    • 0041828907 scopus 로고    scopus 로고
    • Heregulin targets γ-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 protein
    • Li Y., Yu W.-H., Ren J., Huang L., Kharbanda S., Loda M., and Kufe D. Heregulin targets γ-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 protein. Mol. Cancer Res. 1 (2003) 765-775
    • (2003) Mol. Cancer Res. , vol.1 , pp. 765-775
    • Li, Y.1    Yu, W.-H.2    Ren, J.3    Huang, L.4    Kharbanda, S.5    Loda, M.6    Kufe, D.7
  • 25
    • 18744394603 scopus 로고    scopus 로고
    • Galectin-3 enhances cyclin D(1) promoter activity through SP1 and a cAMP-responsive element in human breast epithelial cells
    • Lin H.M., Pestell R.G., Raz A., and Kim H.R. Galectin-3 enhances cyclin D(1) promoter activity through SP1 and a cAMP-responsive element in human breast epithelial cells. Oncogene 21 (2002) 8001-8010
    • (2002) Oncogene , vol.21 , pp. 8001-8010
    • Lin, H.M.1    Pestell, R.G.2    Raz, A.3    Kim, H.R.4
  • 26
    • 11144241063 scopus 로고    scopus 로고
    • Galectins as modulators of tumour progression
    • Liu F.T., and Rabinovich G.A. Galectins as modulators of tumour progression. Nat. Rev. Cancer 5 (2005) 29-41
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 29-41
    • Liu, F.T.1    Rabinovich, G.A.2
  • 27
    • 30044448792 scopus 로고    scopus 로고
    • Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin
    • Macao B., Johansson D.G., Hansson G.C., and Hard T. Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin. Nat. Struct. Mol. Biol. 13 (2006) 71-76
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 71-76
    • Macao, B.1    Johansson, D.G.2    Hansson, G.C.3    Hard, T.4
  • 28
    • 0034685681 scopus 로고    scopus 로고
    • Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis
    • Matarrese P., Tinari N., Semeraro M.L., Natoli C., Iacobelli S., and Malorni W. Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis. FEBS Lett. 473 (2000) 311-315
    • (2000) FEBS Lett. , vol.473 , pp. 311-315
    • Matarrese, P.1    Tinari, N.2    Semeraro, M.L.3    Natoli, C.4    Iacobelli, S.5    Malorni, W.6
  • 29
    • 0029557241 scopus 로고
    • Induction of tumorigenicity by gelectin-3 in a non-tumorigenic human breast carcinoma cell line
    • Nangia-Makker P., Thompson E., Ochieng J., and Raz A. Induction of tumorigenicity by gelectin-3 in a non-tumorigenic human breast carcinoma cell line. Int. J. Oncol. 7 (1995) 1079-1087
    • (1995) Int. J. Oncol. , vol.7 , pp. 1079-1087
    • Nangia-Makker, P.1    Thompson, E.2    Ochieng, J.3    Raz, A.4
  • 30
    • 1542343883 scopus 로고    scopus 로고
    • Extracellular functions of galectin-3
    • Ochieng J., Furtak V., and Lukyanov P. Extracellular functions of galectin-3. Glycoconj. J. 19 (2004) 527-535
    • (2004) Glycoconj. J. , vol.19 , pp. 527-535
    • Ochieng, J.1    Furtak, V.2    Lukyanov, P.3
  • 32
    • 1542343886 scopus 로고    scopus 로고
    • Understanding the biochemical activities of galectin-1 and galectin-3 in the nucleus
    • Patterson R.J., Wang W., and Wang J.L. Understanding the biochemical activities of galectin-1 and galectin-3 in the nucleus. Glycoconj. J. 19 (2004) 499-506
    • (2004) Glycoconj. J. , vol.19 , pp. 499-506
    • Patterson, R.J.1    Wang, W.2    Wang, J.L.3
  • 33
    • 2442693937 scopus 로고    scopus 로고
    • The MUC1 oncoprotein activates the anti-apoptotic PI3K/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts
    • Raina D., Kharbanda S., and Kufe D. The MUC1 oncoprotein activates the anti-apoptotic PI3K/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. J. Biol. Chem. 279 (2004) 20607-20612
    • (2004) J. Biol. Chem. , vol.279 , pp. 20607-20612
    • Raina, D.1    Kharbanda, S.2    Kufe, D.3
  • 34
    • 33748055445 scopus 로고    scopus 로고
    • MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage
    • Raina D., Ahmad R., Kumar S., Ren J., Yoshida K., Kharbanda S., and Kufe D. MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage. EMBO J. 25 (2006) 3774-3783
    • (2006) EMBO J. , vol.25 , pp. 3774-3783
    • Raina, D.1    Ahmad, R.2    Kumar, S.3    Ren, J.4    Yoshida, K.5    Kharbanda, S.6    Kufe, D.7
  • 35
    • 0037124099 scopus 로고    scopus 로고
    • Protein kinase C δ regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling
    • Ren J., Li Y., and Kufe D. Protein kinase C δ regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling. J. Biol. Chem. 277 (2002) 17616-17622
    • (2002) J. Biol. Chem. , vol.277 , pp. 17616-17622
    • Ren, J.1    Li, Y.2    Kufe, D.3
  • 37
    • 30044445260 scopus 로고    scopus 로고
    • MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90
    • Ren J., Bharti A., Raina D., Chen W., Ahmad R., and Kufe D. MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90. Oncogene 25 (2006) 20-31
    • (2006) Oncogene , vol.25 , pp. 20-31
    • Ren, J.1    Bharti, A.2    Raina, D.3    Chen, W.4    Ahmad, R.5    Kufe, D.6
  • 38
    • 0035918199 scopus 로고    scopus 로고
    • Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
    • Schroeder J., Thompson M., Gardner M., and Gendler S. Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J. Biol. Chem. 276 (2001) 13057-13064
    • (2001) J. Biol. Chem. , vol.276 , pp. 13057-13064
    • Schroeder, J.1    Thompson, M.2    Gardner, M.3    Gendler, S.4
  • 39
    • 0032557645 scopus 로고    scopus 로고
    • X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution
    • Seetharaman J., Kanigsberg A., Slaaby R., Leffler H., Barondes S.H., and Rini J.M. X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution. J. Biol. Chem. 273 (1998) 13047-13052
    • (1998) J. Biol. Chem. , vol.273 , pp. 13047-13052
    • Seetharaman, J.1    Kanigsberg, A.2    Slaaby, R.3    Leffler, H.4    Barondes, S.H.5    Rini, J.M.6
  • 44
    • 2942591023 scopus 로고    scopus 로고
    • Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs
    • Takenaka Y., Fukumori T., Yoshii T., Oka N., Inohara H., Kim H.R., Bresalier R.S., and Raz A. Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs. Mol. Cell. Biol. 24 (2004) 4395-4406
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4395-4406
    • Takenaka, Y.1    Fukumori, T.2    Yoshii, T.3    Oka, N.4    Inohara, H.5    Kim, H.R.6    Bresalier, R.S.7    Raz, A.8
  • 45
    • 1542373593 scopus 로고    scopus 로고
    • Expression of galectins in cancer: a critical review
    • van den Brule F., Califice S., and Castronovo V. Expression of galectins in cancer: a critical review. Glycoconj. J. 19 (2004) 537-542
    • (2004) Glycoconj. J. , vol.19 , pp. 537-542
    • van den Brule, F.1    Califice, S.2    Castronovo, V.3
  • 46
    • 0035996593 scopus 로고    scopus 로고
    • Galectin-induced activation of the transcription factors NFAT and AP-1 in human Jurkat T-lymphocytes
    • Walzel H., Blach M., Hirabayashi J., Arata Y., Kasai K., and Brock J. Galectin-induced activation of the transcription factors NFAT and AP-1 in human Jurkat T-lymphocytes. Cell. Signal. 14 (2002) 861-868
    • (2002) Cell. Signal. , vol.14 , pp. 861-868
    • Walzel, H.1    Blach, M.2    Hirabayashi, J.3    Arata, Y.4    Kasai, K.5    Brock, J.6
  • 47
    • 13844262819 scopus 로고    scopus 로고
    • Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response
    • Wei X., Xu H., and Kufe D. Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. Cancer Cell 7 (2005) 167-178
    • (2005) Cancer Cell , vol.7 , pp. 167-178
    • Wei, X.1    Xu, H.2    Kufe, D.3
  • 48
    • 30744474431 scopus 로고    scopus 로고
    • MUC1 oncoprotein stabilizes and activates estrogen receptor alpha
    • Wei X., Xu H., and Kufe D. MUC1 oncoprotein stabilizes and activates estrogen receptor alpha. Mol. Cell 21 (2006) 295-305
    • (2006) Mol. Cell , vol.21 , pp. 295-305
    • Wei, X.1    Xu, H.2    Kufe, D.3
  • 49
    • 27144475302 scopus 로고    scopus 로고
    • Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells
    • Wu L., and Belasco J.G. Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Mol. Cell. Biol. 25 (2005) 9198-9208
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 9198-9208
    • Wu, L.1    Belasco, J.G.2
  • 50
    • 33645119514 scopus 로고    scopus 로고
    • MicroRNAs direct rapid deadenylation of mRNA
    • Wu L., Fan J., and Belasco J.G. MicroRNAs direct rapid deadenylation of mRNA. Proc. Natl. Acad. Sci. USA 103 (2006) 4034-4039
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 4034-4039
    • Wu, L.1    Fan, J.2    Belasco, J.G.3
  • 51
    • 0042818006 scopus 로고    scopus 로고
    • Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress
    • Yin L., and Kufe D. Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress. J. Biol. Chem. 278 (2003) 35458-35464
    • (2003) J. Biol. Chem. , vol.278 , pp. 35458-35464
    • Yin, L.1    Kufe, D.2
  • 52
    • 0036510564 scopus 로고    scopus 로고
    • Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest
    • Yoshii T., Fukumori T., Honjo Y., Inohara H., Kim H.R., and Raz A. Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest. J. Biol. Chem. 277 (2002) 6852-6857
    • (2002) J. Biol. Chem. , vol.277 , pp. 6852-6857
    • Yoshii, T.1    Fukumori, T.2    Honjo, Y.3    Inohara, H.4    Kim, H.R.5    Raz, A.6
  • 53
    • 0037013214 scopus 로고    scopus 로고
    • Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation
    • Yu F., Finley Jr. R.L., Raz A., and Kim H.R. Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. J. Biol. Chem. 277 (2002) 15819-15827
    • (2002) J. Biol. Chem. , vol.277 , pp. 15819-15827
    • Yu, F.1    Finley Jr., R.L.2    Raz, A.3    Kim, H.R.4


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